LOCUS       NM_001134858            7432 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus synemin (Synm), mRNA.
ACCESSION   NM_001134858 XM_001055657
VERSION     NM_001134858.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7432)
  AUTHORS   Zhou,J.
  TITLE     Synemin promotes pulmonary artery smooth muscle cell phenotypic
            switch in shunt-induced pulmonary arterial hypertension
  JOURNAL   ESC Heart Fail 9 (5), 3221-3231 (2022)
   PUBMED   35769011
  REMARK    GeneRIF: Synemin promotes pulmonary artery smooth muscle cell
            phenotypic switch in shunt-induced pulmonary arterial hypertension.
REFERENCE   2  (bases 1 to 7432)
  AUTHORS   Garcia-Pelagio,K.P., Muriel,J., O'Neill,A., Desmond,P.F.,
            Lovering,R.M., Lund,L., Bond,M. and Bloch,R.J.
  TITLE     Myopathic changes in murine skeletal muscle lacking synemin
  JOURNAL   Am J Physiol Cell Physiol 308 (6), C448-C462 (2015)
   PUBMED   25567810
REFERENCE   3  (bases 1 to 7432)
  AUTHORS   Lund,L.M., Kerr,J.P., Lupinetti,J., Zhang,Y., Russell,M.A.,
            Bloch,R.J. and Bond,M.
  TITLE     Synemin isoforms differentially organize cell junctions and desmin
            filaments in neonatal cardiomyocytes
  JOURNAL   FASEB J 26 (1), 137-148 (2012)
   PUBMED   21982947
  REMARK    GeneRIF: We conclude that beta-synemin mediates the association of
            desmin intermediate filaments with Z disks, whereas alpha-synemin
            stabilizes junctional complexes between cardiomyocytes.
REFERENCE   4  (bases 1 to 7432)
  AUTHORS   Luna,G., Lewis,G.P., Banna,C.D., Skalli,O. and Fisher,S.K.
  TITLE     Expression profiles of nestin and synemin in reactive astrocytes
            and Muller cells following retinal injury: a comparison with glial
            fibrillar acidic protein and vimentin
  JOURNAL   Mol Vis 16, 2511-2523 (2010)
   PUBMED   21139996
  REMARK    GeneRIF: Retinal injury induces an upregulation of a complement of
            four intermediate filament proteins, including synemin and nestin,
            in Muller cells.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7432)
  AUTHORS   Sun,N., Critchley,D.R., Paulin,D., Li,Z. and Robson,R.M.
  TITLE     Identification of a repeated domain within mammalian alpha-synemin
            that interacts directly with talin
  JOURNAL   Exp Cell Res 314 (8), 1839-1849 (2008)
   PUBMED   18342854
REFERENCE   6  (bases 1 to 7432)
  AUTHORS   Izmiryan,A., Cheraud,Y., Khanamiryan,L., Leterrier,J.F.,
            Federici,T., Peltekian,E., Moura-Neto,V., Paulin,D., Li,Z. and
            Xue,Z.G.
  TITLE     Different expression of synemin isoforms in glia and neurons during
            nervous system development
  JOURNAL   Glia 54 (3), 204-213 (2006)
   PUBMED   16817202
REFERENCE   7  (bases 1 to 7432)
  AUTHORS   Bhosle,R.C., Michele,D.E., Campbell,K.P., Li,Z. and Robson,R.M.
  TITLE     Interactions of intermediate filament protein synemin with
            dystrophin and utrophin
  JOURNAL   Biochem Biophys Res Commun 346 (3), 768-777 (2006)
   PUBMED   16777071
REFERENCE   8  (bases 1 to 7432)
  AUTHORS   Xue,Z.G., Cheraud,Y., Brocheriou,V., Izmiryan,A., Titeux,M.,
            Paulin,D. and Li,Z.
  TITLE     The mouse synemin gene encodes three intermediate filament proteins
            generated by alternative exon usage and different open reading
            frames
  JOURNAL   Exp Cell Res 298 (2), 431-444 (2004)
   PUBMED   15265691
REFERENCE   9  (bases 1 to 7432)
  AUTHORS   Titeux,M., Brocheriou,V., Xue,Z., Gao,J., Pellissier,J.F.,
            Guicheney,P., Paulin,D. and Li,Z.
  TITLE     Human synemin gene generates splice variants encoding two distinct
            intermediate filament proteins
  JOURNAL   Eur J Biochem 268 (24), 6435-6449 (2001)
   PUBMED   11737198
REFERENCE   10 (bases 1 to 7432)
  AUTHORS   Mizuno,Y., Thompson,T.G., Guyon,J.R., Lidov,H.G., Brosius,M.,
            Imamura,M., Ozawa,E., Watkins,S.C. and Kunkel,L.M.
  TITLE     Desmuslin, an intermediate filament protein that interacts with
            alpha -dystrobrevin and desmin
  JOURNAL   Proc Natl Acad Sci U S A 98 (11), 6156-6161 (2001)
   PUBMED   11353857
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Sep 4, 2014 this sequence version replaced NM_001134858.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.2725.1,
                                           SRR26643291.1827.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840108, SAMN16676806
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1037              JAXUCZ010000001.1  130772788-130773824 c
            1038-1162           JAXUCZ010000001.1  130765941-130766065 c
            1163-1233           JAXUCZ010000001.1  130753076-130753146 c
            1234-7432           JAXUCZ010000001.1  130743891-130750089 c
FEATURES             Location/Qualifiers
     source          1..7432
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..7432
                     /gene="Synm"
                     /gene_synonym="Dmn"
                     /note="synemin"
                     /db_xref="GeneID:308709"
                     /db_xref="RGD:727872"
     exon            1..1037
                     /gene="Synm"
                     /gene_synonym="Dmn"
                     /inference="alignment:Splign:2.1.0"
     CDS             228..4901
                     /gene="Synm"
                     /gene_synonym="Dmn"
                     /note="desmuslin; synemin, intermediate filament protein"
                     /codon_start=1
                     /product="synemin"
                     /protein_id="NP_001128330.1"
                     /db_xref="GeneID:308709"
                     /db_xref="RGD:727872"
                     /translation="MLSWRLQTSSEKAELQELNARLYEYVCRVRELERENLLLEEELR
                     SRLSREDRWAEDQALYAEEARSLRQQLDELSWSTALAEGERDALRRELLDLQREGLEA
                     STARGRLDAELEAQRRELEEALGARAALEALLGRLEAERRDLDAAHERQVRELRARAS
                     SLTMHFRARATGPAAPPPRLRDVHDSYALLVAESWRESMQLYEDEVRELEQALRRGQE
                     SRLQAEDEARLCAQEADALRNQALELEQLRARLEDELLRMREEYGMQAEERQRVIDSL
                     EDEKDALTLAMADRLREYQELLQVKTGLSLEVATYRALLEGESNPEILIWTENIENVP
                     RESRNTSYRYTDSVLQRKNEKNLFPRRKTPWAAVNHSSTLYSNGPGHLDSQTTTAVGN
                     AARRGFLTSCYSSSATTSQQKPLEKTVSSQASLRPVIPTHGFLRNTDAQVKTFSHGPK
                     AEGMGDTLTRRATESVITRESYRGHQGNVAAGAVNSTQSNERTVILGKKLETQATKEQ
                     ERDRSGVVKLKPEEKMFDSKEKASEERNLRWEELTKLDARERESQHLRNEAKGKETLT
                     GRSRKEREVPISLEVSRGSKSEVSTIHLQSSGRKDSANSREREVKTKETKFHLDGKDT
                     AGSLQSDSTTETIAENIVTTILKQFTQSPGAEENVSSLPDTKVTYLDRKEFPGDRKTK
                     TEIVMESKLTEDVDVSDEAGLDYLLSKDVKEVGLKGKSTETVIGEMINLGLKGREGRA
                     KVVNVEIVEEPMSYVGGGKVEFSTPFQVEEVDDVSPSPKGFIEEEEGEGETHMAFSMH
                     QRQRTNQPQVNVPHVEEVTEAGDSEGEQSYFVSTPDEYPGGHDREDDGSVYGQIHIEE
                     ESTIRYSWQDEIAQGTWRRKARGDTGEEKHMKVLEVPSASLGGAFGSAHVKEEASGEL
                     HAEPTIIEKEIKIPHEFHTSIKGVFSSEPRHQLVEVIGQLEETLPERMKEELSALTRQ
                     SQGEPGSVSVDVKKVQSSAGGSVTLMAEVNLSQTVDADQLDLEELSRDEAGEIEKAVE
                     SVVRESLTKRSSPVPRSPDREDGEEAPAGGFLFKRWATRELYSPSGEKDDTDRVFHSS
                     DQRVTQGPVSATVEVTSPTGFVQSHVLEDVSQSVRHVKLGPTEMWRTEQVSYGGPTSP
                     VVEVSEDFSEAVSSEGASRSVRHVTLGPRQNRVSTEVIFRGSVPTGQETGDTGEPDPA
                     ALSVEADISGSGRMPGSQQAHNEKETPFPGPISGAAQVGSNFSTEGSVGTQTFVRHLQ
                     LGSREGFREEIQFIAPIPDRAEWGEEDSGYTRVSLGRSTSIQHIDIVPQRYQASKQVA
                     PQTLGFRDSEGVVLVERSAGMTQATHNFTSDREILKKEENTFQRVISGSPPDSVGDTG
                     AEVTENISRSFRHIQIGPTEEDPSEYIVTSGPLSKTFVLDSSVASPGPGGGADGSSTP
                     CHIALGPKETSFTFQMGVSDTRAIRSWTRDTGSEVEAHSVSHHGGWRVAHSRDEQSAS
                     TSSQASAGDAHQARGEKGTEQAGFDKTVQLQRMVDQRSVASDEKKVALLYLDNEEEEE
                     GEGWF"
     exon            1038..1162
                     /gene="Synm"
                     /gene_synonym="Dmn"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1233
                     /gene="Synm"
                     /gene_synonym="Dmn"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..7432
                     /gene="Synm"
                     /gene_synonym="Dmn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgcagt ggccgcgcgg gccgcgtcct gattggctgg aggctgtggc caagtccacg
       61 gccgcgcaac ccggccacta agtcgggaag ctggccagtc ggtgcgccag tccgtggacc
      121 tccaaggcag cggcaaggcg ggcgcggcgc ggcgcggcgg gacggaggga acaagatcag
      181 ggcaggaggc aagcggttaa tcgaaagggc cccgcacacc cagcaagatg ctgtcctggc
      241 ggctgcagac cagctccgaa aaggccgagc tccaggagct caatgcccgg ctttatgagt
      301 acgtgtgccg ggtgcgagag ctggagcgcg agaacctgct gctggaggag gagctgcgca
      361 gccggctgag ccgggaggac cgctgggccg aagatcaagc gctctacgcc gaggaggcgc
      421 gcagcttgcg acagcagctc gacgaactga gctggtccac ggcgctggcc gagggcgagc
      481 gcgacgcgct gcggagggaa ctgctggacc tgcagcggga aggtttggaa gccagcactg
      541 cccgcggccg cctggatgcc gagctagaag cgcagcggcg ggagctggag gaggcgctgg
      601 gcgcgcgcgc cgccctcgag gcgctgctgg gccggctgga ggcagagcga cgagacctgg
      661 atgcggccca cgagcgccaa gtgcgagagc tacgcgcccg tgccagcagc ctcaccatgc
      721 acttccgagc ccgcgccacc ggccccgccg cgcccccgcc gcgcctgcgg gacgtgcacg
      781 acagctacgc cctgctagtg gccgagtcgt ggagggagag catgcagctg tacgaggacg
      841 aggtgcgcga gctggagcag gcgctgcgcc gcggtcaaga gagccggctc caggcggagg
      901 acgaggcgcg gctgtgcgcg caggaggcgg acgcgctgcg gaaccaggcg ctggagttgg
      961 agcagctgcg tgcgaggctg gaggatgagc tgcttcggat gcgcgaggag tacgggatgc
     1021 aggcggagga gcggcagaga gtgatcgaca gcctggagga tgagaaggat gcccttacct
     1081 tggccatggc tgacaggctg cgggagtacc aggagctcct acaggtgaag acgggcctca
     1141 gcttggaggt agctacctac agggccttgt tggaaggaga aagcaatccg gagatattga
     1201 tctggaccga gaacattgaa aacgtgccac gagagtccag aaacacatcc tatcgctata
     1261 ccgactcagt attacagagg aagaatgaga agaatctctt tccaaggcga aaaacacctt
     1321 gggcagctgt aaatcacagc tcgactttgt attccaacgg gccagggcac cttgactcac
     1381 agacaaccac agctgttgga aatgctgccc gaaggggctt cctgacctcc tgctattctt
     1441 cctcagctac aacctcacag cagaagcccc tggagaaaac tgtcagcagt caagccagtt
     1501 taagaccagt cataccaacc catggctttc taagaaacac tgatgctcaa gtgaaaacat
     1561 tctcccatgg acccaaagct gaaggcatgg gggacaccct cacacggcgg gccacagagt
     1621 ccgttattac cagagagtca tacagaggtc accagggcaa cgtggcggca ggtgctgtga
     1681 acagcactca gtcaaatgag aggactgtca ttctgggaaa gaaattagaa acgcaggcca
     1741 ctaaggagca agagagggac aggtcagggg tggtcaaatt aaagccagag gagaaaatgt
     1801 ttgattctaa agagaaggct tcggaggaaa gaaacttgag gtgggaagag ctgaccaagt
     1861 tagatgcaag agagagggaa agccagcatt taaggaacga ggccaaaggg aaggaaacac
     1921 tgacggggag aagtagaaaa gaaagagaag tgcccatcag tctagaagta tctcggggca
     1981 gcaaatcaga ggtgtccaca atacacttgc agtcatccgg aaggaaggat tctgccaaca
     2041 gtagggaaag agaggtaaag accaaagaga caaagttcca cttggacggc aaggacactg
     2101 ctggctctct gcagagtgac tctacgacag agaccatagc agaaaacatc gtcaccacca
     2161 tccttaagca gtttacccag tctccaggtg ctgaagagaa tgtcagttct ttgccagaca
     2221 caaaggtcac ctacctggac cggaaagagt ttcctggtga caggaaaacc aagacggaaa
     2281 tcgtcatgga gtcgaagctg acagaagacg tcgatgtttc tgatgaagct ggcctggact
     2341 accttctaag caaggatgtc aaggaagtag gactgaaagg gaagtcaaca gagacagtga
     2401 ttggagagat gatcaacctc ggtctaaaag gaagggaggg gagagccaaa gtcgtaaatg
     2461 tggagattgt ggaagagccc atgagctacg taggtggtgg gaaagtagag ttttctaccc
     2521 ccttccaggt ggaagaagtc gatgatgtgt ctcccagccc caaggggttc attgaggaag
     2581 aggagggcga aggagaaacc cacatggcat tctcaatgca tcaacgtcag aggaccaacc
     2641 agccccaggt gaacgtccct catgtggaag aagtgacgga ggcgggcgac tcggaggggg
     2701 agcagagtta tttcgtgtct accccagatg agtaccctgg gggacatgac agagaagatg
     2761 atggctctgt gtatgggcag atccacattg aggaagagtc caccatccgg tactcatggc
     2821 aagacgagat tgcacagggg acttggagaa ggaaagcgag aggtgacacg ggggaagaga
     2881 agcacatgaa ggtcctggag gttccatcgg cttccctggg tggtgccttt ggatctgctc
     2941 acgtgaagga agaagctagt ggtgaactcc acgctgaacc cacaatcatt gagaaagaga
     3001 tcaaaatacc gcatgaattc cacacctcca taaagggcgt cttctccagt gagcctcggc
     3061 atcagttggt ggaggtcatt gggcagctgg aggaaacgtt gcctgagcgc atgaaggaag
     3121 agctgtctgc cctgaccaga cagagtcaag gagagccagg gagtgtctca gtggatgtaa
     3181 agaaagtcca gagctctgct ggcggttctg tgaccttaat ggctgaggtc aacctctcgc
     3241 agactgtaga tgctgatcag ttagacctgg aggagttgag cagggacgaa gctggggaaa
     3301 tagagaaggc tgtggagtca gtggtaagag agagcttgac caagcgctcc agcccagtgc
     3361 ctagaagccc agacagggaa gatggagagg aggcgcctgc cggtggcttt ctcttcaagc
     3421 gctgggccac cagggagctg tatagcccgt ctggtgagaa ggatgatact gaccgggtct
     3481 ttcacagctc ggatcagcgt gttacccagg gcccagtgtc agccaccgtg gaagtgacca
     3541 gcccaacggg ttttgtgcag tctcatgtgc tggaggatgt aagccagtct gtaaggcacg
     3601 ttaaactagg ccccactgag atgtggagga cggaacaggt gtcctacgga ggacccacct
     3661 caccggtggt ggaggtaagt gaagacttca gcgaggcagt cagctccgag ggagccagcc
     3721 gctccgtgag gcacgttaca ctgggtcccc gtcaaaaccg agtgtccaca gaagtcattt
     3781 tccgaggctc tgtgcctacc gggcaggaga caggagacac aggagagcct gaccctgcag
     3841 cactgtctgt ggaagctgac atctcaggga gtggcaggat gcccggctct cagcaggctc
     3901 acaatgaaaa ggaaactcct tttccgggtc ctatttctgg ggcagcccag gttggtagta
     3961 acttttcaac tgaagggtca gtgggtaccc agacttttgt taggcatctc cagttaggct
     4021 ccagagaagg gttcagagaa gaaatccagt tcatagctcc catcccagac agggcagagt
     4081 ggggagaaga ggattctggg tacaccagag tgtctctagg gaggagcacc tccatccagc
     4141 acattgacat cgtgcctcag aggtaccagg cttccaagca ggtggcccca cagacattgg
     4201 gatttaggga ctcagaaggc gtagtcctgg tggagaggtc agcaggtatg acccaggcca
     4261 ctcacaattt cacctcagat agagaaatcc tcaagaagga agagaacaca ttccagaggg
     4321 tcatttctgg gtcccctcca gacagtgtgg gcgacacagg agcagaggtg acagaaaaca
     4381 tcagcagatc cttcaggcac attcaaatag gtcctacaga ggaggacccc tctgaataca
     4441 ttgtcaccag tggacccttg tctaaaacat ttgttcttga cagttccgtg gcatcccctg
     4501 ggccgggtgg gggagcagac ggcagtagca caccatgtca cattgcactg gggcccaaag
     4561 aaacttcatt tacctttcag atgggtgtaa gtgacacgag agccatccgc agctggaccc
     4621 gagacacagg gtcagaagtg gaagctcaca gtgtgtctca ccacggtggc tggagagttg
     4681 ctcacagtag ggatgagcaa tcagccagca ccagctctca ggcctctgct ggggatgcac
     4741 accaggcccg tggagagaaa ggcacggagc aggctggatt tgacaagacg gtgcagctgc
     4801 aaagaatggt agaccaaagg tctgtggctt cagatgagaa gaaagtggcc cttctctatc
     4861 tagacaatga ggaggaagag gagggcgagg gatggttttg ataaccagaa actgtcttgt
     4921 cctgaatggc gctctggaga catatccatg tacaaagcct tcaaaatacc aacatacaag
     4981 cccttcacta agtgttaagt gggggtgtgg ggagggctgg ttatcaatac ctttgtttag
     5041 agaagcctag gccgaagtag tttgcttcag aacttgtatg taaaggttgg agattttaca
     5101 tttgagttgg aactccccta ggctcctttt atctttccta gtcttaagaa gttctttcct
     5161 ctaaactttt ctctccacgc gtggagacag tttatacgag ttttgcacag gtcacaggcg
     5221 tggctcgtat ctgttctact gtctatccta taggcaagac actttaacat tagccaggtt
     5281 aaaataatat attcaaggta ggttttgttg catgtgctaa tatcaaacag gaagctaaca
     5341 ctggaaagga gcataggtgg gcttttctct ctccaaagtc tttttttaaa ttaagaaatt
     5401 tttaaatttt taatttaaga aattatagaa agtaagcaag actgtatggg aaaaaatcta
     5461 ctagatgatt taagaaaaag ttacttatca gagatttaaa gttatgttaa aatggaatga
     5521 attgctttct atgtacagga ctgaaaagag agggcttaga gttatttatg gaaagacagc
     5581 tgtggttcgt tgttggtgcc tcagattcat gtatctgtcc tgattgctca gatttgctgt
     5641 ctctggccac aggcattggc agccaagaat gagaattgct cacagcatcc tttcaaatct
     5701 ttactaggct gggaggtagc agatacattg tgtcctgatc taagctggag cactggttct
     5761 caacctgtgg gtcgaggcga ccctttcaag gcatcgccta agaccatcgg aaaacaccaa
     5821 tgtttacact acgattcgta acagtggaga aattagttat gaagtggcaa ggatgtgatt
     5881 ttacgattgg gggtcaccac gacttgagaa actatattaa agggccgcag cctttggagg
     5941 gttaaggacc actgctctag aagaatgagt cagtgctcct aacaacagaa ccatttctct
     6001 acccggtaca gattgccttg gtaggatttt ctgagctcct agaattaagg acaaaagtgg
     6061 caagagccgt atacgaacct cacaaacact tttgcacttt ggatagaaat catgatggtg
     6121 gtggcattta agttgaatgt aggtagtgtt taggagaggg aaccaggtgc ttccaatgta
     6181 accagcatct gggcccccag agcagactga cagacgacaa aggcctcacc cttgtgggcc
     6241 acacatcatg gaccggaagc tgtgtgccac tgaatttaat gggtgtgttc atttggaatg
     6301 gctcttttac acatggacgt tgtttttaaa gcttccgtct ctgaaggttt ggcatcacat
     6361 aaaaaagcaa aaaggcctct acagtgcagc ggtctgtgag tgcagaatag tagcttccat
     6421 gggtccgaac tgtgcttttg aacccaggcc acaaacctgc ctgtggggct ctgaggaaga
     6481 aggatccgag gtggtgtcat cttcaggtag gggaggagca cggtacagga gggcctccct
     6541 ccccatgtgt cccacaggac gcattcccca ctccggttcc agcaggtggg tgaaagagag
     6601 gttcttcctt gctaagggaa ggagaaatgc agaatggttt aaggtatttc caaagcctgg
     6661 catcggggta caggaagaaa gcaggtttga acagaaagcc catgttacct acctgccagc
     6721 tgaactcagg ggtgtcagac taagacagga gttactgctg tggcttgtcc tctctgacac
     6781 tgtctgagat gccctgattt attcttacca tagtcagaag acctgagtga ttcgttagag
     6841 tgtggctgag gtggtacagc ctgggtataa caatgcaaga cacagttaca atgtcgagtt
     6901 tattatgagt ctaagtgggc ttagctggac gcccttgtcc tggttcctga acttgtccat
     6961 gcatggtggt gtgagcagct tataaatatc tgggcacttc ttctcacttt gaaaaataag
     7021 tgtcttggag tgaaatatta attgtcatct ctaagttgga atcaccatca aggcaatccc
     7081 aggaaggagg agtcctcagc tgtcatcggt tactatgtct ctaggtcact aagggcagag
     7141 cttttaccct tgacattgta gcagctccct gaggtttttg gaatcagtca ctctggagtc
     7201 aaatggacac tgtggtaggg cagggagggt gggggtgcac ccagtctctc ccagtttgtt
     7261 attgagacta caagatactg aatgtttctt agccttccac tggttgtttt gatagtttgc
     7321 tttgacgtgt ttatttagaa ttatctaaga agcttatttt tgctaacctc ctgttcccta
     7381 caaagtgaac tgtcacaaga atatgtagaa ataaagatct gaggggaaaa aa
//
