LOCUS       NM_019166                910 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus synaptogyrin 1 (Syngr1), mRNA.
ACCESSION   NM_019166
VERSION     NM_019166.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Wilhelm,B.G., Mandad,S., Truckenbrodt,S., Krohnert,K., Schafer,C.,
            Rammner,B., Koo,S.J., Classen,G.A., Krauss,M., Haucke,V., Urlaub,H.
            and Rizzoli,S.O.
  TITLE     Composition of isolated synaptic boutons reveals the amounts of
            vesicle trafficking proteins
  JOURNAL   Science 344 (6187), 1023-1028 (2014)
   PUBMED   24876496
REFERENCE   2  (bases 1 to 910)
  AUTHORS   Kotani,T., Toyono,T., Seta,Y., Kitou,A., Kataoka,S. and
            Toyoshima,K.
  TITLE     Expression of synaptogyrin-1 in T1R2-expressing type II taste cells
            and type III taste cells of rat circumvallate taste buds
  JOURNAL   Cell Tissue Res 353 (3), 391-398 (2013)
   PUBMED   23636420
  REMARK    GeneRIF: synaptogyrin-1 plays a regulatory role in transmission at
            the synapses of type III cells and is involved in exocytic function
            with synaptobrevin-2 in a subset of type II cells in rat taste
            buds.
REFERENCE   3  (bases 1 to 910)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   4  (bases 1 to 910)
  AUTHORS   Takamori,S., Holt,M., Stenius,K., Lemke,E.A., Gronborg,M.,
            Riedel,D., Urlaub,H., Schenck,S., Brugger,B., Ringler,P.,
            Muller,S.A., Rammner,B., Grater,F., Hub,J.S., De Groot,B.L.,
            Mieskes,G., Moriyama,Y., Klingauf,J., Grubmuller,H., Heuser,J.,
            Wieland,F. and Jahn,R.
  TITLE     Molecular anatomy of a trafficking organelle
  JOURNAL   Cell 127 (4), 831-846 (2006)
   PUBMED   17110340
REFERENCE   5  (bases 1 to 910)
  AUTHORS   Belfort,G.M., Bakirtzi,K. and Kandror,K.V.
  TITLE     Cellugyrin induces biogenesis of synaptic-like microvesicles in
            PC12 cells
  JOURNAL   J Biol Chem 280 (8), 7262-7272 (2005)
   PUBMED   15590695
REFERENCE   6  (bases 1 to 910)
  AUTHORS   Belfort,G.M. and Kandror,K.V.
  TITLE     Cellugyrin and synaptogyrin facilitate targeting of synaptophysin
            to a ubiquitous synaptic vesicle-sized compartment in PC12 cells
  JOURNAL   J Biol Chem 278 (48), 47971-47978 (2003)
   PUBMED   12928441
  REMARK    GeneRIF: Cellugyrin and synaptogyrin have roles in facilitating
            targeting of synaptophysin to a ubiquitous synaptic vesicle-sized
            compartment
REFERENCE   7  (bases 1 to 910)
  AUTHORS   Janz,R., Sudhof,T.C., Hammer,R.E., Unni,V., Siegelbaum,S.A. and
            Bolshakov,V.Y.
  TITLE     Essential roles in synaptic plasticity for synaptogyrin I and
            synaptophysin I
  JOURNAL   Neuron 24 (3), 687-700 (1999)
   PUBMED   10595519
REFERENCE   8  (bases 1 to 910)
  AUTHORS   Sugita,S., Janz,R. and Sudhof,T.C.
  TITLE     Synaptogyrins regulate Ca2+-dependent exocytosis in PC12 cells
  JOURNAL   J Biol Chem 274 (27), 18893-18901 (1999)
   PUBMED   10383386
REFERENCE   9  (bases 1 to 910)
  AUTHORS   Stenius,K., Janz,R., Sudhof,T.C. and Jahn,R.
  TITLE     Structure of synaptogyrin (p29) defines novel synaptic vesicle
            protein
  JOURNAL   J Cell Biol 131 (6 Pt 2), 1801-1809 (1995)
   PUBMED   8557746
REFERENCE   10 (bases 1 to 910)
  AUTHORS   Baumert,M., Takei,K., Hartinger,J., Burger,P.M., Fischer von
            Mollard,G., Maycox,P.R., De Camilli,P. and Jahn,R.
  TITLE     P29: a novel tyrosine-phosphorylated membrane protein present in
            small clear vesicles of neurons and endocrine cells
  JOURNAL   J Cell Biol 110 (4), 1285-1294 (1990)
   PUBMED   2182650
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB729785.1, DN932005.1, DV724604.1 and U39549.1.
            
            On Oct 17, 2007 this sequence version replaced NM_019166.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U39549.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                CB729785.1         75-146
            73-239              DN932005.1         35-201
            240-534             DV724604.1         46-340
            535-910             U39549.1           504-879
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..910
                     /gene="Syngr1"
                     /note="synaptogyrin 1"
                     /db_xref="GeneID:29205"
                     /db_xref="RGD:3801"
     exon            1..150
                     /gene="Syngr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..756
                     /gene="Syngr1"
                     /note="p29"
                     /codon_start=1
                     /product="synaptogyrin-1"
                     /protein_id="NP_062039.1"
                     /db_xref="GeneID:29205"
                     /db_xref="RGD:3801"
                     /translation="MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIV
                     NEGYLNNPEEEEEFCIYNRNPNACSYGVTVGVLAFLTCLVYLALDVYFPQISSVKDRK
                     KAVLSDIGVSAFWAFFWFVGFCFLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFT
                     WAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMPYAPYVEPSAGSDPTGMGGTYQHP
                     ANAFDAEPQGYQSQGY"
     exon            151..388
                     /gene="Syngr1"
                     /inference="alignment:Splign:2.1.0"
     exon            389..534
                     /gene="Syngr1"
                     /inference="alignment:Splign:2.1.0"
     exon            535..910
                     /gene="Syngr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacgggccgg tggcgcgcgc cgagcggggg gcgccgcgcg gtgcagccac gatggaaggg
       61 ggtgcgtacg gagcgggcaa agccgggggc gccttcgacc cctacaccct ggtgcgacag
      121 ccacatacca tcctgcgcgt cgtgtcttgg gtcttctcca ttgtggtctt cggctccatt
      181 gtgaatgagg gctacctgaa caacccggag gaggaggagg agttctgcat ctacaaccga
      241 aaccccaatg cctgcagcta cggcgtgacc gtgggcgtgt tggccttcct cacctgcctg
      301 gtctacctgg cgcttgatgt gtacttcccg cagatcagca gtgtcaagga ccgcaagaaa
      361 gccgtgctgt ctgacatcgg tgtctcggcc ttctgggcct tcttctggtt cgtgggtttc
      421 tgcttcctgg ccaaccagtg gcaagtctcc aagcccaagg acaaccctct gaacgaaggg
      481 acagacgcag cccgggctgc catcgccttt tcgttcttct ccattttcac gtgggcgggt
      541 caggccgtgc tagccttcca gcggtatcag attggcgccg actcggccct cttctcccag
      601 gactacatgg atcccagcca ggactccagc atgccttatg caccctacgt ggagcccagt
      661 gctgggtcgg accctactgg catgggtggc acctaccagc atccagccaa cgccttcgat
      721 gctgagcccc agggctacca gtcgcagggc tactgagccc cccctgatgg tggtgacagt
      781 gaccgcctac cctgcccctg cccttacatc ctagctcccc tcccaagcac cctgctccct
      841 cccaggtgac cctgcctcgc acatgctcag cctccaagtg attccactga ggcccagtgc
      901 agctggggtg
//
