LOCUS       NM_017109               8608 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus synapsin III (Syn3), mRNA.
ACCESSION   NM_017109
VERSION     NM_017109.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8608)
  AUTHORS   Perlini,L.E., Szczurkowska,J., Ballif,B.A., Piccini,A.,
            Sacchetti,S., Giovedi,S., Benfenati,F. and Cancedda,L.
  TITLE     Synapsin III acts downstream of semaphorin 3A/CDK5 signaling to
            regulate radial migration and orientation of pyramidal neurons in
            vivo
  JOURNAL   Cell Rep 11 (2), 234-248 (2015)
   PUBMED   25843720
  REMARK    GeneRIF: we show that SynIII phosphorylation at the CDK5 site is
            induced by activation of the semaphorin-3A (Sema3A) pathway, which
            is implicated in migration and orientation of cortical pyramidal
            neurons
REFERENCE   2  (bases 1 to 8608)
  AUTHORS   Boyken,J., Gronborg,M., Riedel,D., Urlaub,H., Jahn,R. and Chua,J.J.
  TITLE     Molecular profiling of synaptic vesicle docking sites reveals novel
            proteins but few differences between glutamatergic and GABAergic
            synapses
  JOURNAL   Neuron 78 (2), 285-297 (2013)
   PUBMED   23622064
REFERENCE   3  (bases 1 to 8608)
  AUTHORS   Lam,P.P., Hyvarinen,K., Kauppi,M., Cosen-Binker,L., Laitinen,S.,
            Keranen,S., Gaisano,H.Y. and Olkkonen,V.M.
  TITLE     A cytosolic splice variant of Cab45 interacts with Munc18b and
            impacts on amylase secretion by pancreatic acini
  JOURNAL   Mol Biol Cell 18 (7), 2473-2480 (2007)
   PUBMED   17442889
REFERENCE   4  (bases 1 to 8608)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   5  (bases 1 to 8608)
  AUTHORS   Gitler,D., Xu,Y., Kao,H.T., Lin,D., Lim,S., Feng,J., Greengard,P.
            and Augustine,G.J.
  TITLE     Molecular determinants of synapsin targeting to presynaptic
            terminals
  JOURNAL   J Neurosci 24 (14), 3711-3720 (2004)
   PUBMED   15071120
REFERENCE   6  (bases 1 to 8608)
  AUTHORS   Feng,J., Chi,P., Blanpied,T.A., Xu,Y., Magarinos,A.M., Ferreira,A.,
            Takahashi,R.H., Kao,H.T., McEwen,B.S., Ryan,T.A., Augustine,G.J.
            and Greengard,P.
  TITLE     Regulation of neurotransmitter release by synapsin III
  JOURNAL   J Neurosci 22 (11), 4372-4380 (2002)
   PUBMED   12040043
REFERENCE   7  (bases 1 to 8608)
  AUTHORS   Jaffrey,S.R., Benfenati,F., Snowman,A.M., Czernik,A.J. and
            Snyder,S.H.
  TITLE     Neuronal nitric-oxide synthase localization mediated by a ternary
            complex with synapsin and CAPON
  JOURNAL   Proc Natl Acad Sci U S A 99 (5), 3199-3204 (2002)
   PUBMED   11867766
REFERENCE   8  (bases 1 to 8608)
  AUTHORS   Hosaka,M. and Sudhof,T.C.
  TITLE     Homo- and heterodimerization of synapsins
  JOURNAL   J Biol Chem 274 (24), 16747-16753 (1999)
   PUBMED   10358015
REFERENCE   9  (bases 1 to 8608)
  AUTHORS   Hosaka,M. and Sudhof,T.C.
  TITLE     Synapsin III, a novel synapsin with an unusual regulation by Ca2+
  JOURNAL   J Biol Chem 273 (22), 13371-13374 (1998)
   PUBMED   9593663
REFERENCE   10 (bases 1 to 8608)
  AUTHORS   Kao,H.T., Porton,B., Czernik,A.J., Feng,J., Yiu,G., Haring,M.,
            Benfenati,F. and Greengard,P.
  TITLE     A third member of the synapsin gene family
  JOURNAL   Proc Natl Acad Sci U S A 95 (8), 4667-4672 (1998)
   PUBMED   9539796
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 20, 2020 this sequence version replaced NM_017109.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN12840105,
                              SAMN12840117 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               JAXUCZ010000007.1  19264086-19264227
            143-605             JAXUCZ010000007.1  19277860-19278322
            606-663             JAXUCZ010000007.1  19295443-19295500
            664-755             JAXUCZ010000007.1  19344667-19344758
            756-912             JAXUCZ010000007.1  19403553-19403709
            913-1002            JAXUCZ010000007.1  19406471-19406560
            1003-1065           JAXUCZ010000007.1  19617367-19617429
            1066-1208           JAXUCZ010000007.1  19664868-19665010
            1209-1283           JAXUCZ010000007.1  19671848-19671922
            1284-1386           JAXUCZ010000007.1  19675965-19676067
            1387-1521           JAXUCZ010000007.1  19680339-19680473
            1522-1609           JAXUCZ010000007.1  19681065-19681152
            1610-1901           JAXUCZ010000007.1  19687851-19688142
            1902-8608           JAXUCZ010000007.1  19689804-19696510
FEATURES             Location/Qualifiers
     source          1..8608
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..8608
                     /gene="Syn3"
                     /note="synapsin III"
                     /db_xref="GeneID:29130"
                     /db_xref="RGD:3799"
     exon            1..142
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            143..605
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     CDS             295..2034
                     /gene="Syn3"
                     /note="regulated by Ca+2; synapsin-3-like"
                     /codon_start=1
                     /product="synapsin-3"
                     /protein_id="NP_058805.1"
                     /db_xref="GeneID:29130"
                     /db_xref="RGD:3799"
                     /translation="MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPASPATERRH
                     PQPLAASFSSPGSSLFSSFSSAMKQTPQAPTGLMEPPTPVTPVVQRPRILLVIDDAHT
                     DWSKYFHGKKVNGDIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKIVRSFKPDF
                     ILVRQHAYSMALAEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLG
                     PEKFPLVEQTFFPNHKPMLTAPNFPVVIKLGHAHAGMGKIKVENQHDYQDITSVVAMA
                     KTYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLW
                     VDSCSEMFGGLDICAVKAVHSKNGRDYIIEVMDSSMPLIGEHVEEDKQLMADLVVSKM
                     SQLLVPGASVPSPLRPWGPQTKSAKSPGQGQLGPLLGQPQPRPPPQGGPRQAQSPQPP
                     RSRSPSQQRLSPQGQQPVSPQSGSPQQQRSPGSPQLSRASGGSSPNQASKPTASLSSH
                     TRPPVQGRSTSQQGEEPQKTASPHPHLNKSQSLTNSLSTSDTSHRGTPSEDEAKAETI
                     RNLRKSFASLFSD"
     exon            606..663
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            664..755
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            756..912
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1002
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1065
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1208
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1283
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1386
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1387..1521
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1609
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1901
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
     exon            1902..8608
                     /gene="Syn3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctttttttaa catgcacatt cccgtattac tctatccagc tacaaggagt gtccccagct
       61 tcctactaag gctagaggtc caggcagctc ctcgtctgac ccccagaggt gctgtttctg
      121 aggaacgaca gcagagcaag aggtaaacag agtcctgtga agcccacttc tggtggtgca
      181 gaagccctgg gatcctctga ccccaagcct ccagcttcct gtagctggca acctgcactt
      241 caaacctcat ctagctgatt ttgtgtggaa ggaggcttcc catccatcgc agccatgaac
      301 ttcctccgga ggcggctgtc agacagcagc tttgtggcca acctgcccaa tggctacatg
      361 ccggacctgc agcgcccaga gagctccagt agctccccag catccccagc cacagagaga
      421 aggcatcccc agcccctggc tgcctccttc tcttctccag gatccagcct gttcagctcc
      481 ttctccagtg ccatgaaaca gaccccacag gccccgacag ggctaatgga accaccaact
      541 cctgtcacac ctgtggttca aagacccagg atcttgttgg tcattgatga tgcccacaca
      601 gactggtcga aatattttca tgggaagaaa gtgaatggcg acattgagat ccgggtggaa
      661 caggctgagt tctctgagct gaacctggct gcttatgtca ccggaggctg catggtggac
      721 atgcaagttg tgagaaatgg caccaaaatt gtgcggtcct tcaaacctga cttcattctg
      781 gttagacagc atgcctatag catggccctg gctgaggact accgaagcct ggtcatcggc
      841 ctccagtatg gagggcttcc tgctgtcaac tctctctact ccgtatacaa cttctgcagc
      901 aagccttggg tgttctctca gctcattaag atcttccatt ccttgggtcc tgagaagttt
      961 ccactagtgg agcaaacatt tttccccaac cacaagccaa tgctcacagc cccgaacttc
     1021 cctgtggtga tcaagctggg acacgctcat gctggcatgg gaaagatcaa agtagaaaac
     1081 cagcacgact accaggacat caccagcgtg gtggccatgg ccaaaaccta tgccaccacg
     1141 gaggccttta ttgactccaa gtatgacatc cgcatacaga agatcggatc caactacaag
     1201 gcatacatga gaacctccat ctctggaaac tggaaggcca acacaggctc tgctatgctg
     1261 gagcaggtgg ccatgacgga aaggtacagg ctgtgggtgg acagctgctc agaaatgttc
     1321 ggcggcctag acatctgtgc tgtcaaggcc gttcacagca agaatggcag agattatatc
     1381 attgaggtca tggacagttc aatgccactg attggagaac atgtggagga ggacaagcag
     1441 ttaatggctg accttgttgt ttccaagatg agccaactcc tggtgccagg ggcctcggtg
     1501 ccctcccccc tgagaccttg gggtccacag actaaatctg caaaatctcc agggcaaggc
     1561 cagctaggac ctctgctcgg acagccccag ccaaggccac ctccacaagg gggccctcgt
     1621 caggctcagt ctcctcagcc tcccagatct agaagtccat cccagcagag gctctcccca
     1681 caaggtcagc agcctgtgag tccccagtca ggatccccac agcagcaaag gtcaccaggt
     1741 tctccacagc tatcccgggc atctggcggc agttctccaa accaggcctc caagccaact
     1801 gccagtctca gttcacatac ccggcctcct gtgcagggac gcagcacctc ccagcagggt
     1861 gaagaacccc aaaagacagc atcacctcac ccccacctca acaaatctca gtccctgact
     1921 aacagcctca gcacgtcaga tacctcccat cgaggaaccc caagtgaaga tgaggccaag
     1981 gctgagacaa tccgcaacct gaggaagtcc tttgccagcc tcttctccga ctagcctcta
     2041 tccaggctgg aggacaggag ggcaagaaga ctcagtgact ggagccctgt ctggttccct
     2101 ccttctcagc cttggttcct gatggaaata tgcttcctaa atacatctgt cccaggaact
     2161 ggtgatctac attcccacct ccttgaccat gacattctaa tgctgtctga ctgagcggta
     2221 gccttgagag cccctaggtt cctcaacacg gaccttctag acagacaagg catcactaca
     2281 tccaccatac gcttgctccc tgccgccggt accacgtgag atgtctgtgt ggcttgtttt
     2341 tgcagtctta ttagtatttt gcttgccttt gggctgaggc ccccttctaa gctgtgactc
     2401 acctccatca aatgcatact ttatagtcgg acctcagcaa cacaagaggc aattattttt
     2461 taatggtgtt tttgcaaaca gaaaaaggga agcccagcct gggagcccac tatgcaccca
     2521 aagcaaactc gtgccatcgt tactgggagt aggctggcaa aggccccatc acagctggcc
     2581 ctcatgatga ccttgatgca acagaaagaa gctagaccct atgcaacatg tgggaccttt
     2641 cagaacagag ggaaacccac agagccaaca gcaggaatcc agaagacaga gcctgtgttc
     2701 cctggggaga gggttacagg atgattgtgc ttgtctgacc tcacacagaa agagaatgtg
     2761 gatggctccc tgtcacagga tcagaagaca cagtgatggt tcagcatttt acctgctctg
     2821 aaaaaaggag tcagtaggcc actcaattta cagtggagaa gccttcaaaa gcagtgtgtg
     2881 tgtttttttt ctttaggaga ccttgaagcc ttttggaatt tcttccagaa aaagttccac
     2941 tccaaccttg tttcagtgtt gccatgatga ctacaatggt ttgctgcaga gctaggcaga
     3001 atggtcctaa ttccctttcc agtggccatt cccctgcact agacggcctc ccaggatcac
     3061 atcaccaagt acctggtgct agaaacattg taggtgccag aagcagcctc ttggtccaac
     3121 ccaagacatc agaacagagc aatgtttctc agtacagccg tggccacata aggtgtgccc
     3181 tccctgcact gtgtgaggga gggaagttat taactgaagc agcttctggt tatacctgag
     3241 ttctgcatct gaggcttcct tgaatctcca gaagcacaga agcagtcact ataaggagtc
     3301 tcattcagca actcaggctg gcatagaata tattatgtag cccacgaaag tctcaaactc
     3361 acagtaattc tcctgttttc ttaagtctcc caagtgctga gattacattt acgaaccgcc
     3421 acacccagca agtaattact ttttggtcag ctcagcccag acgagtggca gagacaaagg
     3481 tagagaccct ctcctgcctt ggttcactta gaaccctgta tttctgcaga atgcacctcc
     3541 aggctggttt ccagcaggga tcggctcaat atcaaaagtg gtagctttgc cactgactgc
     3601 tagagatcca gttagccatc aaggtcatcc tctttctcct tccctcttcc ctctttcaag
     3661 atgaagcggt attgagagca agcatactag agttactgca gaagctctcc tttggcctct
     3721 cttcccatat ccttggttag agtggtaagt agcaactgtg acataagatc acgtaggttc
     3781 agtggccact gaggccatag tttggagctg gagatgcagg gtttaggcct aactggaaat
     3841 gaccagaatc aacagcaaat tggctgtggt atgaagtgag gagtgaactg ctgaaggcct
     3901 agaagccctc ccagtaccaa gaagattgca aacttccatg acttcagtgt gaggacagtc
     3961 cgtgagcatg cttgcccaca tctccccaac tcaactgctc ttctatccca ggatgagcat
     4021 ggcagaggct tccagaatgc ttctttaggc taatggggtg gcccagcatg tggtgaggca
     4081 catggcacaa ctgtcagtgc attctcctag acacatccgc tctctggtaa gggaagaggt
     4141 cttgaggcca gcatccacaa gtcatgcttt aggtgggtta tctaaataag aaaagcgatc
     4201 agtctgtgag ttcaagaatg ttgcttcttc ctcctgccct tcccctactc ttagttcttg
     4261 caccttgctc tagaacctct gaagaaaggt ataggtgagg cagaaggaag gaagtgtggg
     4321 aggtaagatt tgaaatatca aaagtagtct gtgaagtgag ttctacagaa gaggatgtgg
     4381 actttaatgc ctggctaatg acccgaatga gtacgttagt acataacatc ttaaagcccc
     4441 attacctcat ttcagactgt agtcctcgtt ctagggagtt cctggtattt gcttcaataa
     4501 cacactgctt ccccaccaga ccttgagaag ccaggcctcc ctcactcatg aggcacatgt
     4561 gcagggaaat cagaagctcc tgacactgat agttgaagtt gctcctttag gaacaacttt
     4621 ctacagaaag ctctgcccca gtcagtaaga tcaagcagag acagagatag gcaggcagac
     4681 aggcaggcag gcaggcaggc aggcaggcag gcaggcaggc aggcagacag acagacagac
     4741 agacagacag acagacagac agacagagac acagagggac agggggtggg gggcaatgga
     4801 cagatggatg cagggacaag aaaccttgca ttctggaaaa ggatgagagg tatcacagaa
     4861 cgccatgcat tgagtggtca agaacacagg tggcagtcat tactttacag cagtttcaac
     4921 ctagtctcaa tactaaaaca gctcctgaca cagtggagta aaaaccagca gcaggaagtt
     4981 tctcaaaatg tgggtcatgg ccctggacta cttataaagg cccaggaaac tttgcttcag
     5041 agcactgaac tgtgaacttg cagttagaag gctcagagcc tgcagcttga tcagcccgct
     5101 gagattcaat ctgaagcaga gcttcaatca ccagccttgc tgaggaccca ctcctttgat
     5161 gggcagaacc agtggctcca taaatgacct tgtggccaaa atattctcac attctgccct
     5221 taaaaacatc tcagcaatca atgacatccc tccaggatcc caatgacagt agcacaaatg
     5281 tctttcacaa tcttaatcag gccaggcatc ctgattttta taaccatgca aggacgtcta
     5341 gattgatgat gtaacactag actatagcca gcacttttaa tttccaactg cctgggaatg
     5401 aaacagaagc caagaatata aatacaggtc ctatggagct cacacatccc tccagtggat
     5461 cgtttttccc ataggctagt ccatgttgct cctgaaactt taaccttcaa taactgtgac
     5521 attcagaggt gggaagggca aaggaacagg gtagggccgt tgtaaatgga acctgaaagg
     5581 ttttatttat tgggttctgc ccttttacac aatcttgacc caagcaagag cattttcttt
     5641 ccaagctgac ctagtgaagc tgagacacaa caaagaccta ttcaatttgt acacaacgac
     5701 cagggactcc aaacacgacc ccaaagaata tctcaaagca gtcagagcag gcttcctcca
     5761 gacctgtcct gtgatcagac ggtgctggat ggactctggc tggtggagaa tcaactttcc
     5821 aggcatagaa tacccacatc atttctcttt ccccaaggct tccagactgc tgcatcccct
     5881 ctagcatgca gttggtctac tccccgagta tcaggtgtgg caattcttca gactcattta
     5941 aataaaaaaa cacaaaccaa acctccatgt aactgggtag ccactgcccg caggaagttc
     6001 tcatgtgaat aggcgtaaaa gcagcaccag caagacgagc ttcctgggca cctgggacgt
     6061 ggcacaggag attggagcag ctgctcagcg gcagctaggt attcaggact cttctgaggt
     6121 tgctccccta gaaaattagg aagtaaatga cacatatatg acagatcaag actggagaac
     6181 ggatggtttc ctaagcctct atcagttgga gtcacctgga gttaaaccaa cagaaatatc
     6241 agtaaaaaga gaaaatagaa aaaccgctcc cagacccagg aaaggaagca gccctcgaca
     6301 tgagagcctt gcacactgta ctgatcaaac atggcttggc tttgtaaaca aggccccagg
     6361 acggcgagca ccagctccca agggcaggcc aatctcgtct gctttgttca gcttcataaa
     6421 atagcttggt ggttcatttt gtgtattcag aagtggtgaa cggctgcagg ttagtcacag
     6481 gcactggtta agccagcctt gcacatacaa gtggtaacat aattatcacc aggaccgcca
     6541 ttctcttcaa gagagcttgc atatgtatct ctaggttcct catcccagag ccaagccggc
     6601 tgatagaatt aacctggtgt cagacgctgt cctagaccag tagctgatta aactgtttta
     6661 tatttagact ttaacaggag gcagcacttt gggcctgact gaagacaaag gggaaggctg
     6721 ggtgacaagc aagccaaatg ggtccattta ggagcataaa ggacacaagc tcttttgtgt
     6781 tgttcccaca aggcatgagc ccagattgat aaaacatgca cacccaggct tcatattcag
     6841 atctaactgg cagacctaga gaagagaaca aaagcaccca aaggtttttt catcaagtct
     6901 cggggttaac actttttata cccaatgctt ttactttgga atatcagaaa caagtgctaa
     6961 cacctcacgt ggggtttcca gtagaggaaa caagaagtca aatcaaatga aatctttaga
     7021 acctggagag ttcagtcaga gtttgcagta caagacctac atttgattct gagaacccac
     7081 gttgacaagc taggcatggc ggtgaacatt tgtaatctca acactgggaa cagagagata
     7141 ggtagagtcc aacagctcac tggctagtcg gcctatcaga gttcctccag gccaagggag
     7201 acacatgtgc acacacagct ttgcatttgc ctagcacact gcaataccct tatccatatt
     7261 tacgtagccc tgccagcatt ggagcacagc agagcacccg tccagctctt ctccaaggct
     7321 caaataggaa gagcacagac cttggaacca actctgaaca caggaaggga ggggaatatc
     7381 caactccgcc agttaggaat ttcagagata tgtatgaagc aatggcctca gcaactgaga
     7441 agaactagaa gaaaaaaagc tacagaattc gaggagtcac aagttggaaa aggttcctcc
     7501 caagactgaa ttaccagcca tgtcaaatgg gtattttgca cttatagtgg ttaaggggag
     7561 gaaaatcaag atcctattac caaaaagtaa ctactggaga atgtaggggc tgagaaagat
     7621 gtgaggctac tgcaacccag tgcactgggg ctggaccact gtcaagtgct tgccgtgggc
     7681 ttctaggctg tcctgctccc gttacagtgc atggaggtga cgtcacaaag ccatgcagtg
     7741 acaagctgct gccaagccat gattccactc attatgctat tagcaataca caaaagctca
     7801 aacacccagt gacaaggacg cacgactctc taagcttctc aaaataaaat gagctgctag
     7861 tcaagaggaa atgctttgag gacactttaa tacaggttgt tgagaggtgc ctaagtctag
     7921 gtttagagca ctctgccact atcttaaact caagacttgc aacatctgcc agttaagccc
     7981 agtgaggctg gacaccagca ccatcaggac ctcccagggc ccatttggaa atgacttatg
     8041 ttctgaaaac ttgtatttgg tgctctggtc atcactgttt cccacgccta cttgtgcgca
     8101 cgcgcacact acatggggca acctaacatt cagccacaag aacatgttct gaaatacaat
     8161 ctagatcaat caaaacttca gggtgacccc tttagccaca cctgaatgaa gcctatggca
     8221 ttcggtggac attaagactg tcctgtagag catagaaaca taatgttaaa ggtcatatag
     8281 cctcgagcct ctagaatatc aactttcttc actgtgatgc aaagactcac aatacatgta
     8341 gcaaaccctc agtacacagt ccgcacacag gactcagtat ctctgcagca catatgccaa
     8401 gccatttcct aatatgcaaa cgtgtttaga acaggaagac gctggcactg tccctatttc
     8461 ctgcagatgc taacagcgtt ttcccctgtg cggcagcagt tgcagcttga atgtgtcact
     8521 acagcatgtt ccaatagtta tttatattaa gtcatttgtg tttgggcttt ctcttgttgt
     8581 agaatgaata aatgttgaat tttgagta
//
