LOCUS       NM_013041               1122 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus synaptonemal complex protein 3 (Sycp3), mRNA.
ACCESSION   NM_013041 XM_001079975
VERSION     NM_013041.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Soh,Y.Q.S., Mikedis,M.M., Kojima,M., Godfrey,A.K., de Rooij,D.G.
            and Page,D.C.
  TITLE     Meioc maintains an extended meiotic prophase I in mice
  JOURNAL   PLoS Genet 13 (4), e1006704 (2017)
   PUBMED   28380054
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1122)
  AUTHORS   Barau,J., Teissandier,A., Zamudio,N., Roy,S., Nalesso,V.,
            Herault,Y., Guillou,F. and Bourc'his,D.
  TITLE     The DNA methyltransferase DNMT3C protects male germ cells from
            transposon activity
  JOURNAL   Science 354 (6314), 909-912 (2016)
   PUBMED   27856912
REFERENCE   3  (bases 1 to 1122)
  AUTHORS   Finsterbusch,F., Ravindranathan,R., Dereli,I., Stanzione,M.,
            Trankner,D. and Toth,A.
  TITLE     Alignment of Homologous Chromosomes and Effective Repair of
            Programmed DNA Double-Strand Breaks during Mouse Meiosis Require
            the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein
  JOURNAL   PLoS Genet 12 (10), e1006393 (2016)
   PUBMED   27760146
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1122)
  AUTHORS   Inoue,H., Ogonuki,N., Hirose,M., Hatanaka,Y., Matoba,S., Chuma,S.,
            Kobayashi,K., Wakana,S., Noguchi,J., Inoue,K., Tanemura,K. and
            Ogura,A.
  TITLE     Mouse D1Pas1, a DEAD-box RNA helicase, is required for the
            completion of first meiotic prophase in male germ cells
  JOURNAL   Biochem Biophys Res Commun 478 (2), 592-598 (2016)
   PUBMED   27473657
REFERENCE   5  (bases 1 to 1122)
  AUTHORS   Sun,X., Brieno-Enriquez,M.A., Cornelius,A., Modzelewski,A.J.,
            Maley,T.T., Campbell-Peterson,K.M., Holloway,J.K. and Cohen,P.E.
  TITLE     FancJ (Brip1) loss-of-function allele results in spermatogonial
            cell depletion during embryogenesis and altered processing of
            crossover sites during meiotic prophase I in mice
  JOURNAL   Chromosoma 125 (2), 237-252 (2016)
   PUBMED   26490168
REFERENCE   6  (bases 1 to 1122)
  AUTHORS   Eijpe,M., Heyting,C., Gross,B. and Jessberger,R.
  TITLE     Association of mammalian SMC1 and SMC3 proteins with meiotic
            chromosomes and synaptonemal complexes
  JOURNAL   J Cell Sci 113 (Pt 4), 673-682 (2000)
   PUBMED   10652260
REFERENCE   7  (bases 1 to 1122)
  AUTHORS   Yuan,L., Liu,J.G., Zhao,J., Brundell,E., Daneholt,B. and Hoog,C.
  TITLE     The murine SCP3 gene is required for synaptonemal complex assembly,
            chromosome synapsis, and male fertility
  JOURNAL   Mol Cell 5 (1), 73-83 (2000)
   PUBMED   10678170
REFERENCE   8  (bases 1 to 1122)
  AUTHORS   Schalk,J.A., Dietrich,A.J., Vink,A.C., Offenberg,H.H., van
            Aalderen,M. and Heyting,C.
  TITLE     Localization of SCP2 and SCP3 protein molecules within synaptonemal
            complexes of the rat
  JOURNAL   Chromosoma 107 (8), 540-548 (1998)
   PUBMED   9933407
REFERENCE   9  (bases 1 to 1122)
  AUTHORS   Chen,J., Silver,D.P., Walpita,D., Cantor,S.B., Gazdar,A.F.,
            Tomlinson,G., Couch,F.J., Weber,B.L., Ashley,T., Livingston,D.M.
            and Scully,R.
  TITLE     Stable interaction between the products of the BRCA1 and BRCA2
            tumor suppressor genes in mitotic and meiotic cells
  JOURNAL   Mol Cell 2 (3), 317-328 (1998)
   PUBMED   9774970
REFERENCE   10 (bases 1 to 1122)
  AUTHORS   Lammers,J.H., Offenberg,H.H., van Aalderen,M., Vink,A.C.,
            Dietrich,A.J. and Heyting,C.
  TITLE     The gene encoding a major component of the lateral elements of
            synaptonemal complexes of the rat is related to X-linked
            lymphocyte-regulated genes
  JOURNAL   Mol Cell Biol 14 (2), 1137-1146 (1994)
   PUBMED   8289794
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 26, 2020 this sequence version replaced NM_013041.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X75785.1, SRR26360181.1847954.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               JAXUCZ010000007.1  24761476-24761588
            114-256             JAXUCZ010000007.1  24765103-24765245
            257-320             JAXUCZ010000007.1  24765802-24765865
            321-355             JAXUCZ010000007.1  24766324-24766358
            356-473             JAXUCZ010000007.1  24768677-24768794
            474-573             JAXUCZ010000007.1  24769834-24769933
            574-672             JAXUCZ010000007.1  24772477-24772575
            673-777             JAXUCZ010000007.1  24775360-24775464
            778-1122            JAXUCZ010000007.1  24775589-24775933
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..1122
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /note="synaptonemal complex protein 3"
                     /db_xref="GeneID:25561"
                     /db_xref="RGD:3795"
     exon            1..113
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..831
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /note="SCP-3"
                     /codon_start=1
                     /product="synaptonemal complex protein 3"
                     /protein_id="NP_037173.1"
                     /db_xref="GeneID:25561"
                     /db_xref="RGD:3795"
                     /translation="MLRGCGEVGAVDCSPEQLNKHLKMVPGGRKHSGKSGKPPLIDQP
                     KKAFDFEKEDKDLSGSEEDAVDEKTQVFDKHGKKRSAGIIEDVGGEVQNMLEKFGADI
                     NKALLAKKKRIEMYTKASFKASNQKIEQIWKTQQEEIQKLNNEYSQQFLSVLQQWELD
                     MQKFEEQGEKLTNLFRQQQKIFQQTRIVQSQRMKAIKQLHEQFIKSLEDVEKNNDNLF
                     TGTQSELKKEMAMLQKKVMMETQQQEMANVRKSLQSMLF"
     exon            114..256
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            257..320
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            321..355
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            356..473
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            474..573
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            574..672
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            673..777
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
     exon            778..1122
                     /gene="Sycp3"
                     /gene_synonym="RNASCP3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagcttggc cagggccagg ctttattttc tcccgcccaa aggctaggct tcgtcagatg
       61 cttcgaggct gcggagaagt cggagcagtc gactgctcac cggagcagct gaacaaacat
      121 ctaaagatgg tgcctggtgg aagaaagcat tctgggaaat ctgggaaacc accattgatt
      181 gatcagccta aaaaagcctt tgactttgag aaagaagata aagatctatc tggttcagaa
      241 gaagatgctg ttgatgaaaa gactcaagta tttgataaac atggaaagaa aagatctgca
      301 ggaataattg aagatgtggg aggtgaagta cagaatatgc tggaaaaatt tggagctgac
      361 atcaacaaag ctcttctggc caagaagaaa agaatagaaa tgtataccaa agcttctttc
      421 aaagccagta accagaaaat tgaacaaatt tggaaaacac aacaagagga aatacagaag
      481 cttaacaatg aatattctca gcaatttttg agtgtgttgc agcagtggga actggatatg
      541 cagaaatttg aggaacaagg agaaaaacta actaatcttt ttcgacaaca gcaaaagatt
      601 tttcagcaga ctagaattgt tcagagccag agaatgaaag caatcaaaca gctacatgag
      661 cagttcataa agagtttgga ggatgtggag aagaacaatg ataatctatt tactggcaca
      721 caaagtgaac ttaaaaaaga aatggctatg ttgcaaaaaa aagttatgat ggaaactcag
      781 cagcaagaga tggcaaatgt tcgaaagtct cttcaatcca tgttattctg atgagtcttt
      841 gaagaaagaa cttgaaccta tgtaatatga tacaattaaa acattagcta agaggcatgc
      901 ctttagtaat tagtttaaac tataacatcg gaagtcatta gcttgtttaa gtggaaggtt
      961 tttgttcctg tcaacttcta aataaatcta agtaactgtg taagtagcag ctattccaat
     1021 gtatcaagct ttctggggtt tgtttgtttg tttgtttgtt tgtttgtttg tttgaatagt
     1081 tgttctctcc actattgtgt caataaagat gatttaaatt ta
//
