LOCUS       NM_172068                982 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus SURF1, cytochrome c oxidase assembly factor
            (Surf1), mRNA.
ACCESSION   NM_172068
VERSION     NM_172068.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 982)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 982)
  AUTHORS   Echaniz-Laguna,A., Ghezzi,D., Chassagne,M., Mayencon,M., Padet,S.,
            Melchionda,L., Rouvet,I., Lannes,B., Bozon,D., Latour,P.,
            Zeviani,M. and Mousson de Camaret,B.
  TITLE     SURF1 deficiency causes demyelinating Charcot-Marie-Tooth disease
  JOURNAL   Neurology 81 (17), 1523-1530 (2013)
   PUBMED   24027061
REFERENCE   3  (bases 1 to 982)
  AUTHORS   Lin,A.L., Pulliam,D.A., Deepa,S.S., Halloran,J.J., Hussong,S.A.,
            Burbank,R.R., Bresnen,A., Liu,Y., Podlutskaya,N., Soundararajan,A.,
            Muir,E., Duong,T.Q., Bokov,A.F., Viscomi,C., Zeviani,M.,
            Richardson,A.G., Van Remmen,H., Fox,P.T. and Galvan,V.
  TITLE     Decreased in vitro mitochondrial function is associated with
            enhanced brain metabolism, blood flow, and memory in
            Surf1-deficient mice
  JOURNAL   J Cereb Blood Flow Metab 33 (10), 1605-1611 (2013)
   PUBMED   23838831
REFERENCE   4  (bases 1 to 982)
  AUTHORS   Martherus,R.S., Sluiter,W., Timmer,E.D., VanHerle,S.J., Smeets,H.J.
            and Ayoubi,T.A.
  TITLE     Functional annotation of heart enriched mitochondrial genes GBAS
            and CHCHD10 through guilt by association
  JOURNAL   Biochem Biophys Res Commun 402 (2), 203-208 (2010)
   PUBMED   20888800
REFERENCE   5  (bases 1 to 982)
  AUTHORS   Agostino,A., Invernizzi,F., Tiveron,C., Fagiolari,G., Prelle,A.,
            Lamantea,E., Giavazzi,A., Battaglia,G., Tatangelo,L., Tiranti,V.
            and Zeviani,M.
  TITLE     Constitutive knockout of Surf1 is associated with high embryonic
            lethality, mitochondrial disease and cytochrome c oxidase
            deficiency in mice
  JOURNAL   Hum Mol Genet 12 (4), 399-413 (2003)
   PUBMED   12566387
REFERENCE   6  (bases 1 to 982)
  AUTHORS   Poyau,A., Buchet,K., Bouzidi,M.F., Zabot,M.T., Echenne,B., Yao,J.,
            Shoubridge,E.A. and Godinot,C.
  TITLE     Missense mutations in SURF1 associated with deficient cytochrome c
            oxidase assembly in Leigh syndrome patients
  JOURNAL   Hum Genet 106 (2), 194-205 (2000)
   PUBMED   10746561
REFERENCE   7  (bases 1 to 982)
  AUTHORS   Poyau,A., Buchet,K. and Godinot,C.
  TITLE     Sequence conservation from human to prokaryotes of Surf1, a protein
            involved in cytochrome c oxidase assembly, deficient in Leigh
            syndrome
  JOURNAL   FEBS Lett 462 (3), 416-420 (1999)
   PUBMED   10622737
REFERENCE   8  (bases 1 to 982)
  AUTHORS   Zhu,Z., Yao,J., Johns,T., Fu,K., De Bie,I., Macmillan,C.,
            Cuthbert,A.P., Newbold,R.F., Wang,J., Chevrette,M., Brown,G.K.,
            Brown,R.M. and Shoubridge,E.A.
  TITLE     SURF1, encoding a factor involved in the biogenesis of cytochrome c
            oxidase, is mutated in Leigh syndrome
  JOURNAL   Nat Genet 20 (4), 337-343 (1998)
   PUBMED   9843204
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 27, 2020 this sequence version replaced NM_172068.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF182952.1, SRR26643298.14618.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840105,
                                           SAMN12840111 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                JAXUCZ010000003.1  30642620-30642710   c
            92-143              JAXUCZ010000003.1  30642371-30642422   c
            144-277             JAXUCZ010000003.1  30642004-30642137   c
            278-360             JAXUCZ010000003.1  30641842-30641924   c
            361-549             JAXUCZ010000003.1  30640921-30641109   c
            550-622             JAXUCZ010000003.1  30640546-30640618   c
            623-785             JAXUCZ010000003.1  30640294-30640456   c
            786-867             JAXUCZ010000003.1  30640065-30640146   c
            868-982             JAXUCZ010000003.1  30639873-30639987   c
FEATURES             Location/Qualifiers
     source          1..982
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..982
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /note="SURF1, cytochrome c oxidase assembly factor"
                     /db_xref="GeneID:64463"
                     /db_xref="RGD:620527"
     exon            1..91
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..937
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /EC_number="7.1.1.9"
                     /note="surfeit 1"
                     /codon_start=1
                     /product="surfeit locus protein 1"
                     /protein_id="NP_742065.1"
                     /db_xref="GeneID:64463"
                     /db_xref="RGD:620527"
                     /translation="MAAVMALTVLRSRITRWPQWACAGPAPFCAVRRSVFGFSVRSGM
                     VCRPHRCCSSTAETAAAKAEDDSFLQWFLLFIPATAFGLGTWQVQRRKWKLKLIAELE
                     SRVMAEPIPLPADPMELKNLEYRPVKVRGHFDHSKELYIMPRTMVDPVREARDAGRLS
                     STESGAYVVTPFHCSDLGVTILVNRGFVPRKKVNPETRQQGQVLGEVDLVGIVRLTEN
                     RKPFVPENNPERSLWYYRDLDAMAKRTGTDPIFIDADFNSTTPGGPIGGQTRVTLRNE
                     HMQYIITWYGLCAATSYLWFRKFVRRTPGV"
     exon            92..143
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
     exon            144..277
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
     exon            278..360
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
     exon            361..549
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
     exon            550..622
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
     exon            623..785
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
     exon            786..867
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
     exon            868..982
                     /gene="Surf1"
                     /gene_synonym="Ab1-205"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggaagtgt tcaaagatgg ctgctgtaat ggctttgact gtcctgcgaa gtcggataac
       61 gcgatggccg cagtgggcct gcgcggggcc ggccccgttc tgcgcggtca gaaggagcgt
      121 ctttgggttt tctgttcgct cagggatggt ctgtaggcca cacaggtgtt gcagttctac
      181 tgctgaaaca gccgccgcta aagcagagga cgactctttt ctccagtggt tcctgctttt
      241 catccctgct actgcttttg gtctggggac ttggcaggtc cagcgccgga aatggaagct
      301 gaaactgatt gcagaattag agtcgcgagt catggctgag cccatccctc tacctgcaga
      361 cccaatggaa ctgaaaaatt tggagtacag gccagtgaag gtcagggggc actttgacca
      421 ctccaaggag ttgtacataa tgcctcggac catggtggac cctgtccgag aggcacgtga
      481 tgctggcaga ttatcctcaa ctgaaagtgg ggcctatgtt gttactcctt tccattgctc
      541 tgacttggga gtcaccatcc tggtcaatag agggtttgtt cccaggaaga aagtgaatcc
      601 ggagaccagg cagcaaggcc aggttctggg agaagtagac ctagtaggca tagtgaggct
      661 gacagaaaac aggaagccct ttgttcctga gaacaaccca gagaggagtc tctggtatta
      721 ccgggacctg gacgctatgg ccaagagaac aggaacggac cccatcttca ttgatgcaga
      781 cttcaatagc acaacacccg gagggcccat tggaggtcaa accagagtaa cccttcggaa
      841 tgagcacatg cagtacatca ttacctggta tggactttgt gcagctacat catacttgtg
      901 gttccgaaaa tttgtgcgtc ggacaccagg tgtgtgaaaa taatgaacct gttcctaacc
      961 actataaaat attttgattt at
//
