LOCUS       NM_001191820            6432 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus SPT6 homolog, histone chaperone and transcription
            elongation factor (Supt6h), mRNA.
ACCESSION   NM_001191820 XM_239258
VERSION     NM_001191820.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6432)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6432)
  AUTHORS   Wang,A.H., Zare,H., Mousavi,K., Wang,C., Moravec,C.E.,
            Sirotkin,H.I., Ge,K., Gutierrez-Cruz,G. and Sartorelli,V.
  TITLE     The histone chaperone Spt6 coordinates histone H3K27 demethylation
            and myogenesis
  JOURNAL   EMBO J 32 (8), 1075-1086 (2013)
   PUBMED   23503590
REFERENCE   3  (bases 1 to 6432)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 6432)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 6432)
  AUTHORS   Okazaki,I.M., Okawa,K., Kobayashi,M., Yoshikawa,K., Kawamoto,S.,
            Nagaoka,H., Shinkura,R., Kitawaki,Y., Taniguchi,H., Natsume,T.,
            Iemura,S. and Honjo,T.
  TITLE     Histone chaperone Spt6 is required for class switch recombination
            but not somatic hypermutation
  JOURNAL   Proc Natl Acad Sci U S A 108 (19), 7920-7925 (2011)
   PUBMED   21518874
REFERENCE   6  (bases 1 to 6432)
  AUTHORS   Yoh,S.M., Cho,H., Pickle,L., Evans,R.M. and Jones,K.A.
  TITLE     The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent
            mRNA splicing and export
  JOURNAL   Genes Dev 21 (2), 160-174 (2007)
   PUBMED   17234882
REFERENCE   7  (bases 1 to 6432)
  AUTHORS   Winkler,M., aus Dem Siepen,T. and Stamminger,T.
  TITLE     Functional interaction between pleiotropic transactivator pUL69 of
            human cytomegalovirus and the human homolog of yeast chromatin
            regulatory protein SPT6
  JOURNAL   J Virol 74 (17), 8053-8064 (2000)
   PUBMED   10933715
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001191820.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760386
                              [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-390               JAXUCZ010000010.1  63638462-63638851   c
            391-537             JAXUCZ010000010.1  63627891-63628037   c
            538-688             JAXUCZ010000010.1  63626724-63626874   c
            689-765             JAXUCZ010000010.1  63626556-63626632   c
            766-958             JAXUCZ010000010.1  63626072-63626264   c
            959-1043            JAXUCZ010000010.1  63625845-63625929   c
            1044-1317           JAXUCZ010000010.1  63624917-63625190   c
            1318-1419           JAXUCZ010000010.1  63624141-63624242   c
            1420-1536           JAXUCZ010000010.1  63623385-63623501   c
            1537-1626           JAXUCZ010000010.1  63622992-63623081   c
            1627-1769           JAXUCZ010000010.1  63622667-63622809   c
            1770-1918           JAXUCZ010000010.1  63620700-63620848   c
            1919-2017           JAXUCZ010000010.1  63620482-63620580   c
            2018-2147           JAXUCZ010000010.1  63619978-63620107   c
            2148-2298           JAXUCZ010000010.1  63619743-63619893   c
            2299-2453           JAXUCZ010000010.1  63619455-63619609   c
            2454-2649           JAXUCZ010000010.1  63619103-63619298   c
            2650-2789           JAXUCZ010000010.1  63618533-63618672   c
            2790-2907           JAXUCZ010000010.1  63618317-63618434   c
            2908-2984           JAXUCZ010000010.1  63617100-63617176   c
            2985-3120           JAXUCZ010000010.1  63616740-63616875   c
            3121-3258           JAXUCZ010000010.1  63616318-63616455   c
            3259-3426           JAXUCZ010000010.1  63616079-63616246   c
            3427-3554           JAXUCZ010000010.1  63615097-63615224   c
            3555-3762           JAXUCZ010000010.1  63613862-63614069   c
            3763-3910           JAXUCZ010000010.1  63613091-63613238   c
            3911-4053           JAXUCZ010000010.1  63612365-63612507   c
            4054-4194           JAXUCZ010000010.1  63610988-63611128   c
            4195-4390           JAXUCZ010000010.1  63608614-63608809   c
            4391-4629           JAXUCZ010000010.1  63608034-63608272   c
            4630-4743           JAXUCZ010000010.1  63607423-63607536   c
            4744-4868           JAXUCZ010000010.1  63607140-63607264   c
            4869-4981           JAXUCZ010000010.1  63604800-63604912   c
            4982-5059           JAXUCZ010000010.1  63604316-63604393   c
            5060-5226           JAXUCZ010000010.1  63604066-63604232   c
            5227-5414           JAXUCZ010000010.1  63603256-63603443   c
            5415-6432           JAXUCZ010000010.1  63601993-63603010   c
FEATURES             Location/Qualifiers
     source          1..6432
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q25"
     gene            1..6432
                     /gene="Supt6h"
                     /note="SPT6 homolog, histone chaperone and transcription
                     elongation factor"
                     /db_xref="GeneID:303281"
                     /db_xref="RGD:1309290"
     exon            1..390
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            391..537
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     CDS             421..5601
                     /gene="Supt6h"
                     /codon_start=1
                     /product="transcription elongation factor SPT6"
                     /protein_id="NP_001178749.1"
                     /db_xref="GeneID:303281"
                     /db_xref="RGD:1309290"
                     /translation="MSDFVESEAEESEEEYNHEGEVVPRVTKKFVEEEDDGEEEEEEN
                     LDDQDERGNLKDFINDDDDEEEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFD
                     LIEENLGVKVKRGQKYRRVKKMSDDDEDDEEEYGKEEHEKEAIAGEIFQDEEGEEGQE
                     AVEAPMAPPDEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFG
                     VDFDYDEFEKYNEYDEELEEDYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSE
                     LESSHLTDQDNEIRATDLPERFQLRSIPVKAAEDDELEEEADWIYRNAFATPTISLQD
                     SCDYLDRGQPTSSFSRKGPSTVQKIKEALGFMRNQHFEVPFIAFYRKEYVEPELHIND
                     LWRVWQWDEKWTQLRIRKENLTRLFEKMQAYQYEQISADPDKPLADGIRALDTTDMER
                     LKDVQSMDELKDVYNHFLLYYGRDIPKMQNAAKASRKKLKRIKEDGDEEGEGEEAEDE
                     EQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTPEQFGENLRDSYQRHETEQFPAEP
                     LELAKDYVCSQFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKG
                     RKDVDEAHYAYSFKYLKNKPVKELRDDQFLKIGLAEDEGLLTIDISIDMKGVEGYGND
                     QTYFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEARES
                     VVKACSRKLYNWLRVAPYRPDQQVEEDDDFMDENQGKGIRVLGIAFSSARDHPVFCAL
                     VNGEGEVTDFLRLPHFTKRRTAWREEEREKKAQDIETLKKFLVNKKPHVVTVAGENRD
                     AQMLIEDVKRIVHELDQGQQLSSIGVELVDNELAILYMNSKKSEAEFRDYPPVLRQAV
                     SLARRIQDPLIEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYCEFINRVNEVGVD
                     VNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTMCHMGPKVFMN
                     CAGFLKIDTASLGDSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESAEDANPAGA
                     LEEILENPERLKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTAYRSPNT
                     EEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQAIRNDETGLWQCPFCQQD
                     NFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVGMT
                     VHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMKRKQ
                     QRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIY
                     QHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCS
                     GGDRKKLEELLIKTKKEKPTFIPYFICACKELPGKFLLGYQPRGKPRIEYVTVTPEGF
                     RYRGQIFPTVNGLFRWFKDHYQDPVPGITPSSSSRTRTPASINATPANINLADLTRAV
                     NALPQNMTSQMFSAIAAVTGQGQNPNATPAQWASSQYGYGGSGGGSSAYHVFPTPAQQ
                     PVATPLMTPSYSYTTPSQPITTPQYHQLQASTTPQSTQAQPQPSSSSRQRQQQPKSNS
                     HAAIDWGKMAEQWLQEKEAERRKQKQRLTPRPSPSPMIESTPMSIAGDATPLLDEMDR
                     "
     exon            538..688
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            689..765
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            766..958
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1043
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1317
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..1419
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1536
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1626
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1769
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1918
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2017
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2018..2147
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2148..2298
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2299..2453
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2454..2649
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2650..2789
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2790..2907
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2908..2984
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3120
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3121..3258
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3259..3426
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3427..3554
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3555..3762
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3763..3910
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3911..4053
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4054..4194
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4195..4390
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4391..4629
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4630..4743
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4744..4868
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4869..4981
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4982..5059
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            5060..5226
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            5227..5414
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            5415..6432
                     /gene="Supt6h"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctacgccaag atggaagtga agactcctta acctgaatct ttatggttcc tttggctaga
       61 gcggcttaag gaacacgctg gccccgcttt gttctgggtg ctctgtggca gctgcgttcc
      121 ttatgtgtct tcagtctgcg ttcgcggact cggaaccaaa gccctagaca ccggagagaa
      181 aaagatcagg aaatgaccct cccactccta gtgacaggga gccggaggtg acgtaggacg
      241 ttaacgcagc agcggcgacg gtggtggtgg cggcggctgc ggagggccct tgcggtgggt
      301 ccgggctacc cttttgcagt ctcggatcgg cgactccatt ttcttccgcg ggggcttagc
      361 gcagcggaga aacagcggcc ttccaagcag ccttcaagga ggctgtgaga agtagcaacc
      421 atgtctgatt ttgtggaaag tgaggctgaa gagtcagaag aagaatacaa tcatgaaggc
      481 gaggtggtac ctagagtcac caagaagttt gtggaagagg aggatgatgg tgaggaggag
      541 gaagaggaga atctagatga tcaagacgag cgaggcaacc tgaaagactt tattaatgat
      601 gatgatgatg aagaggaagg agaggaggat gaaggcagtg actctggtga ctcagaagat
      661 gatgttggcc acaagaagag aaaacgcaca tcctttgatg accgcctgga agatgatgat
      721 tttgacctca ttgaggagaa tttgggtgtt aaagtcaaac gaggacaaaa ataccgacgt
      781 gtcaaaaaaa tgtctgatga tgatgaagat gatgaagagg aatatggcaa agaggaacac
      841 gagaaggagg ccattgcagg ggaaatcttc caagatgaag aaggggaaga agggcaggag
      901 gctgtagagg cccctatggc tcctccagac gaggaggagg aagatgatga agagtcagat
      961 attgatgatt tcattgtgga tgatgatgga cagcctctga aaaaaccgaa atggcgaaaa
     1021 aagcttcctg gatatacaga tgcagccctg caggaagccc aggagatctt cggtgtggac
     1081 tttgactatg atgaatttga gaaatacaat gaatatgatg aagaactgga ggaagactat
     1141 gagtatgagg atgacgaggc tgaaggtgag atccgagtgc gccccaagaa gaccaccaag
     1201 aagcgcgtaa gtcgcaggag catctttgag atgtatgagc caagtgaact ggagagcagt
     1261 cacctcacag accaggacaa tgaaatccga gccactgacc tgcctgagag gttccagctc
     1321 cgctccatcc cagtcaaggc agctgaagat gatgagctag aagaagaagc tgactggatc
     1381 tatagaaatg cctttgcgac accaaccatc tccctccagg acagctgtga ttacctggac
     1441 cgtgggcagc caactagtag cttcagtcgg aaagggccca gcacagttca gaagatcaaa
     1501 gaggccctgg gcttcatgcg gaatcagcat tttgaggtac ctttcattgc cttctaccga
     1561 aaggagtacg tggagcccga gttgcacatc aatgacctgt ggagggtgtg gcagtgggat
     1621 gagaagtgga ctcagctgag aatccgcaaa gagaacctaa cacggctgtt tgagaagatg
     1681 caggcttatc agtatgagca aatttctgct gaccctgata aacctcttgc tgatggcatc
     1741 cgggctttag atactactga catggagagg ctcaaagatg tgcagtcaat ggatgaactg
     1801 aaagatgtct acaaccattt cttactttac tatggccgtg acatccccaa gatgcagaat
     1861 gccgccaagg ctagccggaa aaagctaaaa cgcataaagg aggatggcga tgaagaaggt
     1921 gaaggtgagg aggctgaaga tgaggagcag aggggaccag agctcaagca agcctcccgc
     1981 cgagacatgt acaccatctg ccagagtgcc ggactagatg gcctagccaa aaagtttggc
     2041 ctcacacctg agcagtttgg ggagaacctc cgtgacagct accaacggca tgagacagag
     2101 cagttccctg cagaaccttt ggagctggcc aaggattacg tttgcagcca gttccctaca
     2161 ccagaagctg tgcttgaagg tgcccgatac atggttgctc tacagattgc ccgggagccc
     2221 cttgtcagac aggtgctgag acaaaccttt caggagagag ctaagctaaa cataacccca
     2281 accaagaaag gtagaaagga tgtggatgag gcccactatg cttattcttt taagtactta
     2341 aagaacaagc ctgttaaaga gctaagagac gaccaattcc tcaagatagg cctggctgaa
     2401 gatgaaggcc tgctcaccat tgacatcagc atagacatga agggagtgga agggtatggt
     2461 aatgaccaga catactttga ggagatcaag cagttttact accgggatga gttcagccat
     2521 caagtccagg aatggaaccg gcagcgcact atggccattg agcgagctct gcagcagttc
     2581 ctctatgtgc aaatggccaa agaacttaag aacaaactgc tcgctgaggc cagggagagt
     2641 gttgtaaagg cctgtagccg aaagctctac aactggctgc gagtggcgcc ctaccgacca
     2701 gatcagcagg tagaggagga tgacgacttt atggatgaaa accaggggaa gggcattcga
     2761 gtcttaggca ttgctttctc ctctgccaga gaccaccctg tgttctgtgc cctagtcaat
     2821 ggtgaaggag aagtgactga tttcctccgt ctgccccatt ttaccaaacg gcgaactgcc
     2881 tggagggaag aggagcggga aaagaaggct caagatattg agactctaaa gaagtttctt
     2941 gtgaataaga agcctcatgt agttactgtt gcaggagaaa acagggatgc ccagatgttg
     3001 attgaggatg tgaagcgcat agtgcatgag ctggaccaag gccaacagct ttcttctatt
     3061 ggggtggagc tggttgacaa tgagttggcc attctgtata tgaacagcaa aaaatcagag
     3121 gcagagttcc gtgattatcc accagttttg agacaagcgg tttctctagc ccggcgcatt
     3181 caagaccctc tgatagaatt tgcccaggtg tgcagctctg atgaagacat cctatgtctc
     3241 aagtttcatc ccttgcagga gcatgttgtg aaagaggagc tgctcaacgc cttgtactgt
     3301 gaattcatca atcgggtcaa tgaggttggg gtcgatgtca accgtgccat tgcccatcct
     3361 tacagccagg ccttgatcca gtacgtctgt ggcctgggac ctcgaaaagg gacccacctg
     3421 ctgaagattt tgaaacagaa caacactcga ctcgagagcc ggactcagct ggtcaccatg
     3481 tgtcacatgg gtcccaaagt cttcatgaat tgtgctggct tcctcaagat cgacactgcc
     3541 tctctggggg acagcactga ctcatacatt gaagttcttg atggttctcg agtccaccct
     3601 gaaacatatg agtgggccag aaagatggca gtagatgcct tggaatatga cgagtctgca
     3661 gaggacgcca atcctgcagg agcccttgag gaaatcttgg aaaacccgga gcgactaaag
     3721 gatttagacc ttgatgcctt tgcagaagaa ctagagagac agggctatgg tgacaaacac
     3781 atcacactct atgacatccg agcagagctc agttgtagat ataaggacct ccggacggcc
     3841 taccgctctc ctaacacaga ggagatcttc aatatgctaa ccaaagagac accagagacc
     3901 ttctacattg gaaagctcat catctgtaat gtcacgggca tcgctcacag gcgcccacag
     3961 ggtgagagct atgaccaggc catccgaaat gacgagacag ggctgtggca gtgccccttc
     4021 tgtcaacagg acaacttccc tgagctgagt gaggtctgga accattttga cagtggatcg
     4081 tgccctggcc aggccattgg cgtgaaaaca cggctagaca acggcgtcac tggcttcatc
     4141 cctaccaaat tcctcagtga caaggtggtg aagaggccag aggagcgtgt gaaggtgggg
     4201 atgactgttc actgccgcat catgaagatc gatattgaaa agttcagtgc agacctgacc
     4261 tgccggacct cagacctcat ggacaggaac aatgagtgga aactgcccaa ggacacctac
     4321 tacgacttcg atgccgaagc cgcagaccac aagcaggagg aggacatgaa gcgaaagcag
     4381 cagcggacca catacatcaa gcgagtgatt gcacacccgt ccttccataa cataaatttt
     4441 aagcaagcag aaaagatgat ggagacaatg gaccaagggg acgttatcat tcggccgagc
     4501 agcaaggggg agaaccacct gacagtgacc tggaaagtca gtgacggcat ctaccagcat
     4561 gtggatgtgc gagaggaggg caaggaaaat gccttcagcc tgggagccac tctgtggatc
     4621 aacagtgagg aattcgaaga cttggatgag attgttgccc gctacgtcca gcccatggct
     4681 tcctttgctc gagaccttct gaaccacaag tattaccagg actgtagtgg tggggaccga
     4741 aagaaattag aggagctgct catcaaaact aagaaggaga agcccacctt catcccttac
     4801 ttcatctgtg cctgcaagga actgcccggc aagttcctcc tgggatacca gccccggggt
     4861 aaacccagga tagagtatgt aacagtgact cctgaaggat tccggtaccg gggccagatt
     4921 ttcccaactg tgaatggact cttccggtgg tttaaggatc attatcagga tcctgtacca
     4981 ggcattactc ccagtagcag cagcagaaca cggacccccg cttctatcaa tgctacccca
     5041 gccaacatca atcttgcaga tctgacacgg gctgtgaatg ccttgcctca gaacatgact
     5101 tcacagatgt tcagtgccat tgctgctgtg acaggccaag gacagaaccc caatgctacc
     5161 ccagcccagt gggcatccag ccagtatggc tacggtggca gtggaggagg cagtagcgcc
     5221 taccatgtgt tcccaacgcc agcccaacag ccagtggcca caccactaat gaccccgagc
     5281 tactcctata caaccccgag ccagcccatt accaccccac aataccacca gctccaggcc
     5341 agcactaccc cacagtctac ccaggcccag ccccagcctt cctccagctc ccgacaacgg
     5401 caacagcagc caaagtccaa cagccatgca gctatcgatt ggggcaagat ggccgagcag
     5461 tggctacagg aaaaggaggc agaacgacgg aaacagaaac agcggctgac cccaagaccc
     5521 tctcccagcc ccatgatcga gagcaccccc atgtccattg ctggcgatgc gaccccactc
     5581 ctggacgaga tggatcgata gggggcctgt tcctcggact ctggttacct ttgaagctcc
     5641 aagaggcctg gccacgaata gcctcactcc ctgcccctct ttctttgtcc ataaagtggc
     5701 gtgaaatgac atttcttttt agtggtcagc ctggctggat ggcaggctgg gtggccttgt
     5761 gagcctggtg tgcaccaaac agcagttgtc ccattccagg cctatgctaa ccacctgccc
     5821 tggggccaga ctgggaaagg aatgcagcag ggaggagagc aaaggtggag tagtctggaa
     5881 tgtccccgga agccatttga gtttctgccc ttacctgata caggctacaa tgaggtatca
     5941 agctcaactt gtatatttcc ccagcctgtg tggggagacc gatgctattt attcagtttg
     6001 gaacaggaag gagagggaaa gtgtttctgg tcctgatgtc aataccttgg tggctgtcaa
     6061 agcaggactg tgagggccat gtggagcagt gctgacctgc cagcccctgc ctgccttccc
     6121 tcatcaccta actgcgcctg cttctcacct gtcatttgaa taaacagtgt ttgtacagag
     6181 cacttgccca ggcctctcca gctccctcgc tctgcagggc tgcttcagag cggtttggaa
     6241 ttccaaaaac ttcctctcat aatctaccag agtccaggac tcatattgcc tggggtcacc
     6301 tccctgcctg ctctgagccc ctgaccctgc gtgggcttct tcagttgttg gccatgttga
     6361 gatggagtct ctaacccagg ctggccttgg atctactgaa tgctggaatt acataaataa
     6421 cacacgtgca ct
//
