LOCUS       NM_001107261            4455 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus SPT16 homolog, facilitates chromatin remodeling
            subunit (Supt16h), mRNA.
ACCESSION   NM_001107261 XM_001075690 XM_223981
VERSION     NM_001107261.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4455)
  AUTHORS   Burgess RJ and Zhang Z.
  TITLE     Histone chaperones in nucleosome assembly and human disease
  JOURNAL   Nat Struct Mol Biol 20 (1), 14-22 (2013)
   PUBMED   23288364
  REMARK    Review article
REFERENCE   2  (bases 1 to 4455)
  AUTHORS   Kwak H and Lis JT.
  TITLE     Control of transcriptional elongation
  JOURNAL   Annu Rev Genet 47, 483-508 (2013)
   PUBMED   24050178
  REMARK    Review article
REFERENCE   3  (bases 1 to 4455)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 4455)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 4455)
  AUTHORS   Winkler DD and Luger K.
  TITLE     The histone chaperone FACT: structural insights and mechanisms for
            nucleosome reorganization
  JOURNAL   J Biol Chem 286 (21), 18369-18374 (2011)
   PUBMED   21454601
  REMARK    Review article
REFERENCE   6  (bases 1 to 4455)
  AUTHORS   Pogribny IP, Ross SA, Tryndyak VP, Pogribna M, Poirier LA and
            Karpinets TV.
  TITLE     Histone H3 lysine 9 and H4 lysine 20 trimethylation and the
            expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in
            hepatocarcinogenesis induced by methyl deficiency in rats
  JOURNAL   Carcinogenesis 27 (6), 1180-1186 (2006)
   PUBMED   16497704
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474040.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001075690.1, XM_223981.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4455
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..4455
                     /gene="Supt16h"
                     /note="SPT16 homolog, facilitates chromatin remodeling
                     subunit"
                     /db_xref="GeneID:305851"
                     /db_xref="RGD:1310032"
     exon            1..130
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..3208
                     /gene="Supt16h"
                     /note="suppressor of Ty 16 homolog"
                     /codon_start=1
                     /product="FACT complex subunit SPT16"
                     /protein_id="NP_001100731.1"
                     /db_xref="GeneID:305851"
                     /db_xref="RGD:1310032"
                     /translation="MAVTLDKDAYYRRVKRLYSNWRKGEDEYASIDAIVVSVGVDEEI
                     VYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPA
                     ITLLVREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWSDCLNKEGFD
                     KVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLA
                     ESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMG
                     IRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLKELRHGVKICDVYNSVMDVVK
                     KQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGK
                     KPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDDEEEEEEKDEAEDL
                     LGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKS
                     NVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYT
                     YLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRI
                     IKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEA
                     HVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQF
                     YTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFE
                     VPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFD
                     MVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPE
                     GFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEE
                     SDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRG
                     SNRGSRHSSAPPKKKRK"
     exon            131..223
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            224..394
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            395..547
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            548..694
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            695..846
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            847..1019
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1110
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1184
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1297
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1363
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1459
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1575
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1729
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1857
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..1993
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            1994..2120
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            2121..2239
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            2240..2365
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            2366..2478
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            2479..2554
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            2555..2724
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            2725..2854
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            2855..2984
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3062
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
     exon            3063..4455
                     /gene="Supt16h"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgggtggcg gagctgggac ctcgcgtgat tctcggagcc cgacggaaag cggcgtccag
       61 ggctatggct gtgactctgg acaaagacgc gtactaccgg cgagttaaga gactgtacag
      121 taactggcgg aaaggagaag atgagtatgc cagtattgat gccattgttg tatcggtggg
      181 tgttgatgaa gaaattgtat atgccaagtc aactgcctta cagacgtggc tctttggtta
      241 tgaactaact gatacaatca tggtcttctg tgatgacaaa atcatcttca tggccagcaa
      301 aaagaaggtg gagtttctga aacagattgc caatactaaa ggcaatgaga atgctaatgg
      361 agctcctgcc atcacactgc ttgtcagaga aaagaatgaa agtaataaga gcagctttga
      421 caaaatgatt gaagccatta aagaaagcaa gaacggcaag aaaattggag tgttcagcaa
      481 agacaagttc cctggagaat tcatgaagag ctggagtgac tgtcttaaca aggagggctt
      541 tgacaaagta gacatcagcg ctgttgtggc atacactatt gctgtgaaag aggatggtga
      601 gctcaacctg atgaagaaag cagccagcat tacctctgag gtcttcaaca agttcttcaa
      661 ggaaagagtc atggaaatag tggatgcaga tgagaaagtt cggcatagca aattggctga
      721 gtctgtggaa aaggccatcg aagagaaaaa atacctagcc ggggcagacc cttctactgt
      781 ggaaatgtgt taccctccta tcattcagag tggtggcaac tacaatctca agttcagtgt
      841 ggtgagtgat aaaaatcata tgcattttgg agccattact tgtgccatgg gcattcgctt
      901 taaatcatac tgctccaacc ttgttcgcac tctgatggtt gaccctactc aggaagttca
      961 agaaaattac aactttttac ttcaacttca agaggagttg ctaaaggaat taagacatgg
     1021 tgtgaagata tgtgatgtgt ataactctgt catggatgtg gttaagaagc agaagccaga
     1081 actgctgaac aaaattacaa aaaacctagg atttgggatg ggaattgaat tccgtgaagg
     1141 ctctctagtg atcaatagta aaaatcagta caagctaaag aaagggatgg ttttcagcat
     1201 caacctagga ttttcagacc tgactaacaa agaagggaaa aaaccagaag agaaaaccta
     1261 tgccctgttt attggtgaca ctgtgcttgt agatgaggat ggtccagcca ctgtccttac
     1321 atctgtgaag aagaaggtaa agaacgtggg cattttcctc aagaatgagg acgatgagga
     1381 ggaggaggag gagaaagatg aggcggagga ccttttggga agaggttcta gagcagcgtt
     1441 acttactgaa agaacacgga atgagatgac tgcagaagag aagcgaagag cccatcagaa
     1501 ggaactggca gcacagctca acgaggaagc gaagaggagg ctgacagagc agaaagggga
     1561 acagcagatt cagaaggctc gaaaatctaa tgtgtcctat aaaaacccat ctctgatgcc
     1621 taaggaacca catattcggg aaatgaagat ctatattgat aagaaatacg agactgtgat
     1681 aatgcctgtg tttggcattg ccacaccctt ccatattgcc acaatcaaga acataagtat
     1741 gtctgtcgaa ggagactata cttacttgcg aatcaacttc tattgtccag gaagtgctct
     1801 gggcaggaac gagggcaaca tctttcctaa ccctgaagct acttttgtca aggaaattac
     1861 ataccgagct tcaaatatga aagcacctgg ggagcagact gtacccgcct taaatcttca
     1921 gaatgctttt cgaattataa aagaagtgca gaaacgttac aagaccagag aagctgaaga
     1981 gaaagaaaaa gagggcattg taaaacaaga ctcactggtg atcaacctaa acagaagtaa
     2041 tccaaagctg aaagatctat acattcgccc aaacattgcc caaaagagaa tgcaaggctc
     2101 cctggaggct cacgtcaatg gtttccgctt cacatctgtt cgaggagaca aggtggatat
     2161 tttgtacaat aatatcaagc acgcactctt ccagccctgt gatggcgaga tgattattgt
     2221 tttgcacttt cacctcaaga atgctatcat gttcgggaag aagcggcaca cagacgtaca
     2281 gttctacaca gaagttggag agatcactac agatttgggg aaacatcaac acatgcatga
     2341 ccgagatgac ctatatgctg agcagatgga aagagagatg agacacaaac tgaaaacagc
     2401 ctttaagaac ttcattgaaa aagtagaggc tctaacaaag gaggaactgg agtttgaagt
     2461 accattcagg gatctggggt ttaatggggc tccctacagg agtacctgcc tccttcagcc
     2521 cactagtagt gcactggtaa atgctacaga gtggccaccc tttgtggtga cactggatga
     2581 agtggagctg atccactttg agagggtcca atttcacctg aagaactttg acatggtgat
     2641 tgtctacaag gattacagca agaaagtcac gatgatcaac gccattcctg ttgcctctct
     2701 agaccccatc aaggagtggc taaattcctg tgacctaaag tacacagaag gtgttcagtc
     2761 cctcaactgg actaaaatca tgaagaccat cgttgacgac cctgaaggct tctttgaaca
     2821 aggtggctgg tctttcctgg aacctgaggg tgagggcagt gatgctgagg acggggactc
     2881 ggagtctgaa attgaagatg agaccttcaa tccttccgag gatgactatg aagaggaaga
     2941 agaggacagt gatgaagact attcatcaga agctgaagaa tcagattatt ctaaggaatc
     3001 tctgggaagt gaagaagaaa gcgggaaaga ctgggatgag ctagaagaag aagcacgaaa
     3061 agcggaccga gaaagccgtt atgaggagga ggaagaacag agccgaagta tgagccggaa
     3121 gaggaaggcg tctgtacata gttcaggccg tggctctaac cgcggttcca gacacagctc
     3181 tgcacccccg aagaaaaaga gaaagtaata tgaaccttgg gtcctatgct ccattctttc
     3241 tgcaaacaac tcctaaaatg acatgacata gaaactgttt ttccttttgg ttctgttgaa
     3301 gttttgccgt ttgtgtttat gggtttaggg gccatttgtg cggaccaagc tactcgggga
     3361 attccaggcc taccaggaca tgtgccagtg gccccgatca gatggctggc aagggaggcg
     3421 gtgttgaagg gcaggaggct cctcccactg ttgataccat ttattctttt cttctgacaa
     3481 cttatctttg gtatctcaaa gctgaattac caagacagtg gtatgagctc accactattt
     3541 ctactatggt tcttttttct ttactttttt atttttcctg gctttttgag acagtcttgc
     3601 tatgcagcca tggctgacct tgaagtcgat gtaaaccagg ctagcctcaa atgtatgatc
     3661 ctcttactct gcctcccaag tgctgggact acaggcctga gtcaccatac ttagccaaag
     3721 cgtggttctg gcccagagtc agtcctccat ccgtcccttt atcagtttga gatctgaagt
     3781 tctcaagaag gttcttgggt ttgctgatgg ttgtgataag cacagctgag ctaaaggcag
     3841 agcgggctgg tgtctggtct taggttgttc tggtttcttg cctggtgcac attctgggtg
     3901 tttttgctgc attggaagac aaatactggc actccgtggc tgggtttttc ctccttacaa
     3961 gtccatatgt ggtacagtgc tcgatcgcac atcaccactg tctcctctga tccatctaag
     4021 gaagaatggc catgcctcat ctgctgcagg tgaaatctag agggaggctt acaggagtca
     4081 acacggatct cgaagagtaa gtcatgtctt ggcctagaat atcttgacaa gaagagaagc
     4141 aggaagaagg ccacacccac aaggctgggc tctgctgctc ctccctttcc tttgtctgca
     4201 gtgtcctgtg tcggttgctt ctgatgatga gctttaagat actggggggc tctctcttgc
     4261 cgtcctcccc tgcaggttct ctgcatccac ctgtcccact ttgcctcctc tgttctgtac
     4321 ctttatgaga aggggcttct cggattttat gtttgtttgt tttctctcct tagcagtagg
     4381 acttgatatt ttgaattttg gaagaactaa aagataaata aactgggatt ttttttgttt
     4441 tgttttgttt tttgt
//
