LOCUS       NM_001007147            2497 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Sad1 and UNC84 domain containing 1 (Sun1), mRNA.
ACCESSION   NM_001007147 XM_341041
VERSION     NM_001007147.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2497)
  AUTHORS   Sharma,V.P., Williams,J., Leung,E., Sanders,J., Eddy,R.,
            Castracane,J., Oktay,M.H., Entenberg,D. and Condeelis,J.S.
  TITLE     SUN-MKL1 Crosstalk Regulates Nuclear Deformation and Fast Motility
            of Breast Carcinoma Cells in Fibrillar ECM Microenvironment
  JOURNAL   Cells 10 (6), 1549 (2021)
   PUBMED   34205257
  REMARK    GeneRIF: SUN-MKL1 Crosstalk Regulates Nuclear Deformation and Fast
            Motility of Breast Carcinoma Cells in Fibrillar ECM
            Microenvironment.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2497)
  AUTHORS   Ishiguro,K., Kim,J., Shibuya,H., Hernandez-Hernandez,A., Suzuki,A.,
            Fukagawa,T., Shioi,G., Kiyonari,H., Li,X.C., Schimenti,J., Hoog,C.
            and Watanabe,Y.
  TITLE     Meiosis-specific cohesin mediates homolog recognition in mouse
            spermatocytes
  JOURNAL   Genes Dev 28 (6), 594-607 (2014)
   PUBMED   24589552
REFERENCE   3  (bases 1 to 2497)
  AUTHORS   Link,J., Leubner,M., Schmitt,J., Gob,E., Benavente,R., Jeang,K.T.,
            Xu,R. and Alsheimer,M.
  TITLE     Analysis of meiosis in SUN1 deficient mice reveals a distinct role
            of SUN2 in mammalian meiotic LINC complex formation and function
  JOURNAL   PLoS Genet 10 (2), e1004099 (2014)
   PUBMED   24586178
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2497)
  AUTHORS   Horn,H.F., Kim,D.I., Wright,G.D., Wong,E.S., Stewart,C.L., Burke,B.
            and Roux,K.J.
  TITLE     A mammalian KASH domain protein coupling meiotic chromosomes to the
            cytoskeleton
  JOURNAL   J Cell Biol 202 (7), 1023-1039 (2013)
   PUBMED   24062341
REFERENCE   5  (bases 1 to 2497)
  AUTHORS   Davidson,E.H., Sultan,S.M., Butala,P., Knobel,D. and Warren,S.M.
  TITLE     Lacunocanalicular fluid flow transduces mechanical tension stress
            during distraction osteogenesis
  JOURNAL   J Craniofac Surg 24 (5), 1558-1564 (2013)
   PUBMED   24036726
REFERENCE   6  (bases 1 to 2497)
  AUTHORS   Zhang,X., Lei,K., Yuan,X., Wu,X., Zhuang,Y., Xu,T., Xu,R. and
            Han,M.
  TITLE     SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the
            nucleus during neurogenesis and neuronal migration in mice
  JOURNAL   Neuron 64 (2), 173-187 (2009)
   PUBMED   19874786
REFERENCE   7  (bases 1 to 2497)
  AUTHORS   Stewart-Hutchinson,P.J., Hale,C.M., Wirtz,D. and Hodzic,D.
  TITLE     Structural requirements for the assembly of LINC complexes and
            their function in cellular mechanical stiffness
  JOURNAL   Exp Cell Res 314 (8), 1892-1905 (2008)
   PUBMED   18396275
REFERENCE   8  (bases 1 to 2497)
  AUTHORS   Crisp,M., Liu,Q., Roux,K., Rattner,J.B., Shanahan,C., Burke,B.,
            Stahl,P.D. and Hodzic,D.
  TITLE     Coupling of the nucleus and cytoplasm: role of the LINC complex
  JOURNAL   J Cell Biol 172 (1), 41-53 (2006)
   PUBMED   16380439
REFERENCE   9  (bases 1 to 2497)
  AUTHORS   Padmakumar,V.C., Libotte,T., Lu,W., Zaim,H., Abraham,S.,
            Noegel,A.A., Gotzmann,J., Foisner,R. and Karakesisoglou,I.
  TITLE     The inner nuclear membrane protein Sun1 mediates the anchorage of
            Nesprin-2 to the nuclear envelope
  JOURNAL   J Cell Sci 118 (Pt 15), 3419-3430 (2005)
   PUBMED   16079285
REFERENCE   10 (bases 1 to 2497)
  AUTHORS   Bray,J.D., Chennathukuzhi,V.M. and Hecht,N.B.
  TITLE     Identification and characterization of cDNAs encoding four novel
            proteins that interact with translin associated factor-X
  JOURNAL   Genomics 79 (6), 799-808 (2002)
   PUBMED   12036294
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085844.1.
            
            On Nov 22, 2004 this sequence version replaced XM_341041.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085844.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2497
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..2497
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /note="Sad1 and UNC84 domain containing 1"
                     /db_xref="GeneID:360773"
                     /db_xref="RGD:1359142"
     exon            1..47
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            48..144
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..2341
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /codon_start=1
                     /product="SUN domain-containing protein 1"
                     /protein_id="NP_001007148.1"
                     /db_xref="GeneID:360773"
                     /db_xref="RGD:1359142"
                     /translation="MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEP
                     VFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPA
                     FSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLK
                     GGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTL
                     RPRKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFS
                     LWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDM
                     GQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIG
                     SIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQP
                     LLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQ
                     KLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEA
                     QAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYF
                     SQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSA
                     PRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGH
                     PEYTCLYRFRVHGEPIQ"
     exon            145..339
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            340..521
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            522..548
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            549..728
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            729..822
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            823..881
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            882..1027
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1267
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1354
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1398
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1399..1510
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1765
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1766..1850
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1966
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1967..2134
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            2135..2227
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2465
                     /gene="Sun1"
                     /gene_synonym="Unc84a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcaagagt tgctatgtac aaagaggggg atggagcagc taagcagcat ggtctgagcc
       61 ggtgaacatg gacttttctc ggctgcacac atacacccca ccccagtgtg tgccagagaa
      121 cactggctat acctacgcac tcagttctag ttattcttcg gatgctctgg attttgagac
      181 tgaacacaga ttggaacctg tctttgactc tccaaggatg tcccgccgta gcttgcgcct
      241 gatcacaaca acagctgcat acagcagtgg ggacggccag actgttgaca ctcacatcag
      301 caccagcagg gccaccccgg ccaaggggag agaaaccagg acagtcaaac agagaagtgc
      361 aagcaagcca gcttttagta tcaaccacct gtcagggaag ggcttgtcct caagcacaag
      421 ccatgacagc tcttgcagcc tgcggagtgc cacggtgctg cggcatcctg tgctagacga
      481 gtctctgatt cgtgagcaga ccaaagtgga ccacttctgg ggtctcgatg atgatggcga
      541 ccttaaaggt ggaaataaag ctgccactca gggaaatggt gaactggcag cagaggtggc
      601 gagcagcaac ggatacacct gccgcgactg caggatgctc tcggctcgga cagacgctct
      661 cacagcccac tctgccgtcc acgggcccac ctcaagggtt tactccagag ataggactct
      721 cagaccccgg aaggcagcct ctggaacctt ctggtggcta gggagtggct ggtaccaatt
      781 tgttactttg atttcctggc tgaatgtgtt tcttcttacc aggtgccttc gaaatatttg
      841 caaggttttt gtcttgctgc tcccactcct acttttatta ggtgctggtt tctccttgtg
      901 gggccagggc aacttcttct cactcctacc aatgttgaat tggacggcca tgcagccagc
      961 gcagagggtg gacaatccca aggacatgca cagacccggc cctctttccc cgagtccacc
     1021 tctcaaggtt gatcccatgg cttcccagtg gcctcaggag agtgatatgg ggcagaagat
     1081 agcctctttg agtgcacagt gccacaacca tgatgagaga ctcgcagagc tgacagtcct
     1141 gcttcagaaa ctccagatac gggtagacca agtggatgac ggcagggaag ggctgtcact
     1201 gtgggtcaag gatatggttg gacagcacct gcaggagatt ggctccatag aaccacctga
     1261 tgctaagact gacttcctga ctttacacca tgaccatgaa gtgcgtctct ccagtttgga
     1321 agatgttctt agaaaactga ctgaaaaatc tgaggctatc cagaaggagc tggaggaaac
     1381 caagctgaga gcaggcagca gggatgaaga gcagcccctc cttgaccgtg tgcagcacct
     1441 agaactggag ctgaacctgc tgaagtcaca gctgtcggac tggcagcatc tgaggagcag
     1501 ctgtgagcag gctgatgccc gcatccagga gactgtgcag ctcatgttct ctgaggacca
     1561 gccgggcggc tccctcgagt ggctgttaca gaagctttct tctcggttcg tgagcaagga
     1621 tgagctgcag gtgcttttgc atgaccttga gctgaaacta ctgcagaata tcacacacca
     1681 catcaccgtc acaggccagg ctccgacatc cgaggccatt gtgtctgcca tgagtcaggc
     1741 agggatttca ggaatcacag aagcgcaagc acatatcatt gtgaacaatg ctctgaggct
     1801 gtactcccaa gacaagactg ggatggtgga ctttgctctg gagtctggag gtggcagcat
     1861 cctaagcact cggtgctctg agacctatga gaccaagacg gcactgctga gcctgttcgg
     1921 ggtcccactg tggtacttct cacagtcacc tcgagtggta atccagcccg acatctaccc
     1981 ggggaattgc tgggcattta agggttccca ggggtacctg gtagttcgct tgtccatgaa
     2041 gatctaccca accacgttca ccatggagca cattccaaag acgctgtcac cgactggtaa
     2101 catctccagt gcccccagag actttgcagt ctatggactg gaaaccgagt atcaggaaga
     2161 ggggcagcct ctgggacggt tcacctatga ccaggaaggg gactcactcc agatgttcca
     2221 cacactggaa agacctgacc aagggttcca gatagtagag ctccgggttc tgtccaactg
     2281 gggccaccct gagtacactt gcctctaccg gttccgagtc cacggagagc ccatccagta
     2341 gagcactcca gccatgtaca tgtctgtata taccaagacg ccataacact ggaactcatt
     2401 gagcaagaga gcacataagc ataggacctg tcagtcaccc ttcaataaat gtatgatagc
     2461 catgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
