LOCUS       NM_012695               1000 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus sulfotransferase family 2A,
            dehydroepiandrosterone (DHEA)-preferring, member 6 (Sult2a6), mRNA.
ACCESSION   NM_012695
VERSION     NM_012695.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Ogura,K., Satsukawa,M., Okuda,H., Hiratsuka,A. and Watabe,T.
  TITLE     Major hydroxysteroid sulfotransferase STa in rat liver cytosol may
            consist of two microheterogeneous subunits
  JOURNAL   Chem Biol Interact 92 (1-3), 129-144 (1994)
   PUBMED   8033248
REFERENCE   2  (bases 1 to 1000)
  AUTHORS   Takahashi,M., Homma,H. and Matsui,M.
  TITLE     Developmental changes in the isoelectric variants of rat hepatic
            hydroxysteroid sulphotransferase
  JOURNAL   Biochem J 293 (Pt 3) (Pt 3), 795-800 (1993)
   PUBMED   8352748
REFERENCE   3  (bases 1 to 1000)
  AUTHORS   Ogura,K., Sohtome,T., Sugiyama,A., Okuda,H., Hiratsuka,A. and
            Watabe,T.
  TITLE     Rat liver cytosolic hydroxysteroid sulfotransferase
            (sulfotransferase a) catalyzing the formation of reactive sulfate
            esters from carcinogenic polycyclic hydroxymethylarenes
  JOURNAL   Mol Pharmacol 37 (6), 848-854 (1990)
   PUBMED   2113604
REFERENCE   4  (bases 1 to 1000)
  AUTHORS   Ogura,K., Kajita,J., Narihata,H., Watabe,T., Ozawa,S., Nagata,K.,
            Yamazoe,Y. and Kato,R.
  TITLE     cDNA cloning of the hydroxysteroid sulfotransferase STa sharing a
            strong homology in amino acid sequence with the senescence marker
            protein SMP-2 in rat livers
  JOURNAL   Biochem Biophys Res Commun 166 (3), 1494-1500 (1990)
   PUBMED   2306259
REFERENCE   5  (bases 1 to 1000)
  AUTHORS   Song,C.S., Kim,J.M., Roy,A.K. and Chatterjee,B.
  TITLE     Structure and regulation of the senescence marker protein 2 gene
            promoter
  JOURNAL   Biochemistry 29 (2), 542-551 (1990)
   PUBMED   2302387
REFERENCE   6  (bases 1 to 1000)
  AUTHORS   Barnes,S., Buchina,E.S., King,R.J., McBurnett,T. and Taylor,K.B.
  TITLE     Bile acid sulfotransferase I from rat liver sulfates bile acids and
            3-hydroxy steroids: purification, N-terminal amino acid sequence,
            and kinetic properties
  JOURNAL   J Lipid Res 30 (4), 529-540 (1989)
   PUBMED   2754334
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M33329.1.
            
            [WARNING] On Jun 12, 2024 this sequence was replaced by
            NM_012695.4.
            
            On Jun 6, 2007 this sequence version replaced NM_012695.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M33329.1, FQ209563.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1000
                     /gene="Sult2a6"
                     /gene_synonym="BAST I; RATSMP2A; RATSMP2B; Smp2a; ST-41;
                     St2a2; ST2A6; Sult2a4l1; Sult2al1"
                     /note="sulfotransferase family 2A, dehydroepiandrosterone
                     (DHEA)-preferring, member 6"
                     /db_xref="GeneID:24902"
                     /db_xref="RGD:3727"
     exon            1..170
                     /gene="Sult2a6"
                     /gene_synonym="BAST I; RATSMP2A; RATSMP2B; Smp2a; ST-41;
                     St2a2; ST2A6; Sult2a4l1; Sult2al1"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..892
                     /gene="Sult2a6"
                     /gene_synonym="BAST I; RATSMP2A; RATSMP2B; Smp2a; ST-41;
                     St2a2; ST2A6; Sult2a4l1; Sult2al1"
                     /EC_number="2.8.2.2"
                     /EC_number="2.8.2.14"
                     /note="Sult2al1, sulfotransferase family 2A,
                     dehydroepiandrosterone (DHEA)-preferring-like 1; bile
                     acid:3'phosphoadenosine-5'phosphosulfate:sulfotransferase
                     I; alcohol sulfotransferase A; hydroxysteroid
                     sulfotransferase A; androsterone-sulfating
                     sulfotransferase; STA; AD-ST; ST-40; sulfotransferase 2A2;
                     senescence marker protein 2A gene, exons 1 and 2;
                     sulfotransferase family 2A, dehydroepiandrosterone
                     (DHEA)-preferring, member 4-like 1"
                     /codon_start=1
                     /product="sulfotransferase 2A6"
                     /protein_id="NP_036827.3"
                     /db_xref="GeneID:24902"
                     /db_xref="RGD:3727"
                     /translation="MPDYTWFEGIPFPAFGIPKETLQNVCNKFVVKEEDLILLTYPKS
                     GTNWLIEIVCLIQTKGDPKWIQSVTIWDRSPWIETDLGYDMLIKKKGPRLITSHLPMH
                     LFSKSLFSSKAKVIYLIRNPRDVLVSGYYFWGKTTLAKKPDSLGTYVEWFLKGYVPYG
                     SWFEHIRAWLSMRELDNFLLLYYEDMKKDTMGTIKKICDFLGKKLEPDELDLVLKYSS
                     FQVMKENNMSNYNLMEKELILPGFTFMRNGTTGDWKNHFTVAQAEAFDKVFQEKMAGF
                     PPGMFPWD"
     exon            171..379
                     /gene="Sult2a6"
                     /gene_synonym="BAST I; RATSMP2A; RATSMP2B; Smp2a; ST-41;
                     St2a2; ST2A6; Sult2a4l1; Sult2al1"
                     /inference="alignment:Splign:2.1.0"
     exon            380..506
                     /gene="Sult2a6"
                     /gene_synonym="BAST I; RATSMP2A; RATSMP2B; Smp2a; ST-41;
                     St2a2; ST2A6; Sult2a4l1; Sult2al1"
                     /inference="alignment:Splign:2.1.0"
     exon            507..601
                     /gene="Sult2a6"
                     /gene_synonym="BAST I; RATSMP2A; RATSMP2B; Smp2a; ST-41;
                     St2a2; ST2A6; Sult2a4l1; Sult2al1"
                     /inference="alignment:Splign:2.1.0"
     exon            602..779
                     /gene="Sult2a6"
                     /gene_synonym="BAST I; RATSMP2A; RATSMP2B; Smp2a; ST-41;
                     St2a2; ST2A6; Sult2a4l1; Sult2al1"
                     /inference="alignment:Splign:2.1.0"
     exon            780..1000
                     /gene="Sult2a6"
                     /gene_synonym="BAST I; RATSMP2A; RATSMP2B; Smp2a; ST-41;
                     St2a2; ST2A6; Sult2a4l1; Sult2al1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctggaatcct aacaggacct acacagagct atttataatg ccagactata cttggtttga
       61 aggaatacct tttcctgcct ttgggattcc aaaagaaact ttgcaaaatg tttgtaataa
      121 gtttgtggtg aaagaagaag atttgatctt attgacttat cccaagtcag gaacaaactg
      181 gctgattgaa attgtctgct tgattcagac caagggagat cccaagtgga tccaatctgt
      241 gaccatctgg gatcgctcac cctggataga gactgattta ggatatgata tgttaatcaa
      301 aaagaaagga ccacgactca taacctccca tcttcccatg catcttttct ccaagtctct
      361 cttcagttcc aaggccaagg tgatctatct catcagaaat cccagagatg ttcttgtttc
      421 tggttattat ttctggggta agacaactct tgcgaagaag ccagactcac tgggaacgta
      481 tgttgaatgg ttcctcaaag gatatgttcc gtatggatca tggtttgagc acatccgtgc
      541 ctggctgtct atgcgagaat tagacaactt cttgttactg tactatgaag acatgaaaaa
      601 ggatacaatg ggaaccataa agaagatatg tgacttccta gggaaaaaat tagagccaga
      661 tgagctggat ttggtcctca agtacagttc cttccaagtc atgaaagaaa acaacatgtc
      721 caattataat ctcatggaga aggaactgat tcttcctggt tttactttca tgagaaacgg
      781 cactactggg gactggaaga atcacttcac tgtagcccaa gctgaagcct ttgataaagt
      841 gtttcaggag aaaatggccg gtttccctcc agggatgttc ccatgggatt aaaatttcaa
      901 aagttttaaa tattttatga acattgattt ttatgtttct gttgttctat gtctgaataa
      961 gtgaatgtgg tcattgaata aattctattc tggcattgtg
//
