LOCUS       NM_001013177            3169 bp    mRNA    linear   ROD 01-FEB-2024
DEFINITION  Rattus norvegicus sulfotransferase family 1C member 2A (Sult1c2a),
            mRNA.
ACCESSION   NM_001013177 XM_008766828 XM_236811
VERSION     NM_001013177.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3169)
  AUTHORS   Runge-Morris,M. and Kocarek,T.A.
  TITLE     Expression of the sulfotransferase 1C family: implications for
            xenobiotic toxicity
  JOURNAL   Drug Metab Rev 45 (4), 450-459 (2013)
   PUBMED   24028175
  REMARK    Review article
REFERENCE   2  (bases 1 to 3169)
  AUTHORS   Brand,W., Boersma,M.G., Bik,H., Hoek-van den Hil,E.F., Vervoort,J.,
            Barron,D., Meinl,W., Glatt,H., Williamson,G., van Bladeren,P.J. and
            Rietjens,I.M.
  TITLE     Phase II metabolism of hesperetin by individual
            UDP-glucuronosyltransferases and sulfotransferases and rat and
            human tissue samples
  JOURNAL   Drug Metab Dispos 38 (4), 617-625 (2010)
   PUBMED   20056724
REFERENCE   3  (bases 1 to 3169)
  AUTHORS   Senggunprai,L., Yoshinari,K. and Yamazoe,Y.
  TITLE     Inhibitory effects of kynurenic acid, a tryptophan metabolite, and
            its derivatives on cytosolic sulfotransferases
  JOURNAL   Biochem J 422 (3), 455-462 (2009)
   PUBMED   19548878
  REMARK    Erratum:[Biochem J. 2009 Nov 1;423(3):442]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3169)
  AUTHORS   Xiangrong,L., Johnk,C., Hartmann,D., Schestag,F., Kromer,W. and
            Gieselmann,V.
  TITLE     Enzymatic properties, tissue-specific expression, and lysosomal
            location of two highly homologous rat SULT1C2 sulfotransferases
  JOURNAL   Biochem Biophys Res Commun 272 (1), 242-250 (2000)
   PUBMED   10872834
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC092564.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001013177.3.
            
            On or before Aug 24, 2014 this sequence version replaced
            XM_008766828.1, NM_001013177.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092564.1, FQ209913.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3169
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..3169
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /note="sulfotransferase family 1C member 2A"
                     /db_xref="GeneID:316153"
                     /db_xref="RGD:1305885"
     exon            1..44
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
     exon            45..123
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
     exon            124..301
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
     CDS             151..1041
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /EC_number="2.8.2.1"
                     /note="rSULT1C2A; sulfotransferase K2; sulfotransferase
                     family, cytosolic, 1C, member 1; sulfotransferase 1C2;
                     sulfotransferase K2-like; sulfotransferase family,
                     cytosolic, 1C, member 2a"
                     /codon_start=1
                     /product="sulfotransferase 1C2A"
                     /protein_id="NP_001013195.2"
                     /db_xref="GeneID:316153"
                     /db_xref="RGD:1305885"
                     /translation="MALAPELSRQTKLKEVAGIPLMDPTVNNWSQIQTFKAKPDDLLI
                     CTYPKSGTTWIQEIVNMIEQNGDVEKCQRTIIQHRHPVIEWARPPQPSGVDKANAMPA
                     PRILRTHLPPQLLPPSFWTNNCKYLYVARNAKDCMVSYYHFYRMCQVLPNPGTWNEYF
                     ETFINGKVSWGSWFDHVKGWWEMRDRYQILFLFYEDMKRDPKREIQKVMQFMGKNLDE
                     EVVDKIVLETSFEKMKDNPLTNFSTIPKTIMDQSISLFMRKGIVGDWKNHFTVAQNER
                     FDEIYEQKLDGTSLNFCMEL"
     exon            302..427
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
     exon            428..525
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
     exon            526..652
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
     exon            653..747
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
     exon            748..928
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
     exon            929..3097
                     /gene="Sult1c2a"
                     /gene_synonym="RGD1562392; RGD1565421; ST1C2A; Sult1c1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgggcagtc cagcttttag actggtgaaa actcgagttt gaagcctagg tctgcttctg
       61 cccttgaggt atccaggtac cattgtgcac tgagcaggac tgaaaagaac aaagtttatt
      121 ctggaactaa accttcttcc ctgagacatc atggccctgg ccccagaatt gagcagacag
      181 acaaaactga aagaggtcgc agggatccca ctgatggatc caactgtcaa caactggagt
      241 cagattcaga ccttcaaggc aaagccagat gacctcctca tctgtactta ccctaaatca
      301 gggacaacat ggattcaaga aattgtcaac atgattgagc agaatgggga tgtagagaag
      361 tgccagagaa ccatcattca acaccgacac cctgttattg agtgggctcg gccaccccag
      421 ccttcaggtg tggacaaagc caatgcgatg ccagctccaa ggatattaag gacccatctt
      481 ccccctcagc tgctgccacc ttctttctgg acaaacaact gtaagtacct ttatgtggct
      541 cgaaacgcca aagactgcat ggtttcctac taccacttct acagaatgtg ccaggtgctc
      601 cccaatccag gcacctggaa tgagtatttt gaaaccttca tcaatggaaa agtaagttgg
      661 ggatcttggt ttgaccatgt gaaaggatgg tgggaaatgc gagacagata ccagattctc
      721 ttcctcttct atgaagacat gaagagggac ccaaagcgtg aaatccagaa ggtaatgcag
      781 ttcatgggca agaatttgga tgaagaggtc gtggataaaa tagtcctgga gacatcgttt
      841 gagaaaatga aagacaatcc tttgacaaat ttttctacaa tccccaagac tatcatggac
      901 cagtccattt cccttttcat gagaaaagga attgtgggtg attggaaaaa ccactttact
      961 gtggcccaga atgagaggtt tgatgaaatc tatgagcaaa agttggatgg aacctctcta
     1021 aacttctgca tggaactctg atcaagatga gaagatagac atcaaggaca ggagtctgtc
     1081 tgcaagcctc aatccagcca aaggaagatc agaaagcaaa ctgtaaatgc caaggactgt
     1141 gacaccgact ctgttattac tgacatcaca ttacaattca caaaatcata ttatgtccag
     1201 tgtatacttt ctccactatt cagtacaaat cagtaagatg gcttaataag ctaataaata
     1261 aacaaacttg aatagtataa attttatgat gacatctttc taggaggtat agcctatatt
     1321 ctaactctaa ataactatct tatgcacaaa aacacaaata ttagaaatca tctaaatgaa
     1381 tgtacagaaa ttcctaatgt ctttctgctc aatcggtatt tttcatggtt acagtgggaa
     1441 gactcagttt gtggacaact tgttgcaaca tgctcactgg aacattttct acctggtagg
     1501 aggaaactga gggaaggact tcaaggagat gtcagaaatc caaatcttaa taaacagaat
     1561 cctagttcta aagcataaaa gaaacagaag aaaggcatga gggtgacctt tggaaagcac
     1621 aaattgtgtc ttgaaaaaag cagaatggat gcttggtgtt caacttgcag ccagttgagt
     1681 tttggtctcc tgtcatctct tctgaggaac agcttgtact tttgcccact ttagcagagt
     1741 ccatctgcat ttgcttgcca gcatacttcc ttccacctcc cactcgctcc atgtcttggg
     1801 catcctttta ctcccagtaa ccaggcaata tggagaacac agcatgttgc acgatggctc
     1861 ggaagacgga aaggcaaaca cgtttcgggt cacaaattct cagcacttac cctttcactt
     1921 tagttgcaga tgtcagcact gctaagctga gatcagcagg agcagcctgt ggtatgagca
     1981 ggatatatat gtgagttcag ggtacctagc atgagctaca atgacatttg ctttctatca
     2041 ctcaaatgta cactttctcc taaatgttga ggacgtgcgc acagcatgtg ttactaccag
     2101 caagagctat gagaaggtgt agtagaagtt agtggatgga agctaagaaa ctggaacatg
     2161 gcctagaaga aaatgagtgc tcctggccct gggtcttcct ttcccttgtt tcttggccat
     2221 gaaaaattca ataaaatgag gtggttagtt ttgctttgcc atttaccctc accatgatat
     2281 tctgtccatc tctccacaga atgtaaattc caaacccaag agctaaaata aagcttctgt
     2341 ctttataagt tgctttcccc agatattgtt ataatgaaag aaagctcact aatacattcc
     2401 caatgatgtg gttataaaat actagaaaag tctgaaattt tgttgaactt atagacaatc
     2461 gcttggttac tgccgaaatc taatcatatg tgtatagtta attaacaatg tctattatat
     2521 taaaaaatta tatcctaatt gtattgtaaa tttttattgt ttgcttctaa gtcttgaaat
     2581 tattcaaagt ttctctaggt agagagtccc ctcttacaat ccaaactaaa ctgaagtccc
     2641 tacatctgcc tcctttcagg gttaagttca taagagccca gagtcactct agcctataaa
     2701 aggaatgact ctggtctcca accatctact ggttaactgt agatttaagg taaactttgg
     2761 aaacataata gtgtcgaact taagcctctt ttggcttcat ttttctggga gtttcctttg
     2821 tattcagaaa ttaaaatagc agaacttgaa agagataaat ggtaaaacat actatgttgg
     2881 ctttgtacac cattgtattc ataatttacc cattggcaat ttttaactat tacttttaga
     2941 gaaaagaatt aatcaagtaa atgaaacatt acatcagaag agtagttaag taactgttag
     3001 aacgtttata aacattttag ttttattagc attgacttat gattatttta ctagcacgtc
     3061 tctatataca caaaattcaa taaaagagtt tcagttaaaa aaaaaaaaaa aaaaaaaaaa
     3121 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
