LOCUS       NM_001009618             782 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus SUB1 regulator of transcription (Sub1), mRNA.
ACCESSION   NM_001009618 XM_342200
VERSION     NM_001009618.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Lopez,C.R., Singh,S., Hambarde,S., Griffin,W.C., Gao,J., Chib,S.,
            Yu,Y., Ira,G., Raney,K.D. and Kim,N.
  TITLE     Yeast Sub1 and human PC4 are G-quadruplex binding proteins that
            suppress genome instability at co-transcriptionally formed G4 DNA
  JOURNAL   Nucleic Acids Res 45 (10), 5850-5862 (2017)
   PUBMED   28369605
REFERENCE   2  (bases 1 to 782)
  AUTHORS   Moir,R.D. and Willis,I.M.
  TITLE     Regulation of pol III transcription by nutrient and stress
            signaling pathways
  JOURNAL   Biochim Biophys Acta 1829 (3-4), 361-375 (2013)
   PUBMED   23165150
  REMARK    Review article
REFERENCE   3  (bases 1 to 782)
  AUTHORS   Dieci,G., Bosio,M.C., Fermi,B. and Ferrari,R.
  TITLE     Transcription reinitiation by RNA polymerase III
  JOURNAL   Biochim Biophys Acta 1829 (3-4), 331-341 (2013)
   PUBMED   23128323
  REMARK    Review article
REFERENCE   4  (bases 1 to 782)
  AUTHORS   Redshaw,N., Camps,C., Sharma,V., Motallebipour,M., Guzman-Ayala,M.,
            Oikonomopoulos,S., Thymiakou,E., Ragoussis,J. and Episkopou,V.
  TITLE     TGF-beta/Smad2/3 signaling directly regulates several miRNAs in
            mouse ES cells and early embryos
  JOURNAL   PLoS One 8 (1), e55186 (2013)
   PUBMED   23390484
REFERENCE   5  (bases 1 to 782)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   6  (bases 1 to 782)
  AUTHORS   Jeong,Y., Leskow,F.C., El-Jaick,K., Roessler,E., Muenke,M.,
            Yocum,A., Dubourg,C., Li,X., Geng,X., Oliver,G. and Epstein,D.J.
  TITLE     Regulation of a remote Shh forebrain enhancer by the Six3
            homeoprotein
  JOURNAL   Nat Genet 40 (11), 1348-1353 (2008)
   PUBMED   18836447
REFERENCE   7  (bases 1 to 782)
  AUTHORS   Werten,S. and Moras,D.
  TITLE     A global transcription cofactor bound to juxtaposed strands of
            unwound DNA
  JOURNAL   Nat Struct Mol Biol 13 (2), 181-182 (2006)
   PUBMED   16415882
REFERENCE   8  (bases 1 to 782)
  AUTHORS   Shakib,K., Norman,J.T., Fine,L.G., Brown,L.R. and
            Godovac-Zimmermann,J.
  TITLE     Proteomics profiling of nuclear proteins for kidney fibroblasts
            suggests hypoxia, meiosis, and cancer may meet in the nucleus
  JOURNAL   Proteomics 5 (11), 2819-2838 (2005)
   PUBMED   15942958
REFERENCE   9  (bases 1 to 782)
  AUTHORS   Ge,H. and Roeder,R.G.
  TITLE     Purification, cloning, and characterization of a human coactivator,
            PC4, that mediates transcriptional activation of class II genes
  JOURNAL   Cell 78 (3), 513-523 (1994)
   PUBMED   8062391
REFERENCE   10 (bases 1 to 782)
  AUTHORS   Soma,G., Kitahara,N. and Andoh,T.
  TITLE     Molecular cloning and characterization of a cDNA clone for a
            protein specifically expressed in embryo as well as in a chemically
            induced pancreatic B cell tumor of rat
  JOURNAL   Biochem Biophys Res Commun 124 (1), 164-171 (1984)
   PUBMED   6208900
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088346.1.
            
            On Jan 13, 2005 this sequence version replaced XM_342200.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088346.1, EV773683.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q16"
     gene            1..782
                     /gene="Sub1"
                     /gene_synonym="Rpo2tc1"
                     /note="SUB1 regulator of transcription"
                     /db_xref="GeneID:192269"
                     /db_xref="RGD:621582"
     exon            1..122
                     /gene="Sub1"
                     /gene_synonym="Rpo2tc1"
                     /inference="alignment:Splign:2.1.0"
     exon            123..195
                     /gene="Sub1"
                     /gene_synonym="Rpo2tc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..507
                     /gene="Sub1"
                     /gene_synonym="Rpo2tc1"
                     /note="PC4; p14; positive cofactor 4; pR-ET2 encoded
                     oncodevelopmental protein; RNA polymerase II
                     transcriptional coactivator; SUB1 homolog, transcriptional
                     regulator"
                     /codon_start=1
                     /product="activated RNA polymerase II transcriptional
                     coactivator p15"
                     /protein_id="NP_001009618.1"
                     /db_xref="GeneID:192269"
                     /db_xref="RGD:621582"
                     /translation="MPKSKELVSSSSSGSDSDSEVEKKLKRKKQVVPEKPVKKQKPGE
                     SSRALASSKQSSSSRDDNMFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKG
                     ISLNMEQWSQLKEQISDIDDAVRKL"
     exon            196..318
                     /gene="Sub1"
                     /gene_synonym="Rpo2tc1"
                     /inference="alignment:Splign:2.1.0"
     exon            319..427
                     /gene="Sub1"
                     /gene_synonym="Rpo2tc1"
                     /inference="alignment:Splign:2.1.0"
     exon            428..758
                     /gene="Sub1"
                     /gene_synonym="Rpo2tc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggctggagc ggagcgtgag tgcgcgggac cctaggccaa ttcctcgagg ctgcagccag
       61 gccgacctca ggctaccgtc gccccttcgc tctccttgcc gggagaaata gaagctctta
      121 agaatgccta aatcaaagga acttgtttct tcgagctctt caggcagtga ttctgacagc
      181 gaagttgaaa aaaagttaaa gaggaaaaag caagttgttc cagagaaacc tgtgaagaag
      241 caaaagcctg gtgagagttc tagagcactg gcatcctcca agcagagtag cagcagcaga
      301 gatgataaca tgttccagat tggaaagatg agatatgtca gtgttcggga ctttaaagga
      361 aaaattctaa ttgatattag agaatattgg atggactcag aaggtgaaat gaaaccaggg
      421 agaaaaggta tttctttaaa catggaacaa tggagccagc tgaaggaaca gatctctgac
      481 atagatgacg cagtaagaaa gctgtaaagt ctgagccata tcaagcctgt actgtcgtag
      541 ctgttttact ctgtcttttc acattggctt ttgttttcta aatgttgttt tccacgctgt
      601 tgtatatttg gattgcagaa caatttgtaa gacaaatact tttttttaat gtgcattatt
      661 aaaatgttct aagtgaagct aattgtcaac tttattaaag aggattgctt tgtgcccctt
      721 acctagtgta aaataaagtc agatcattac aatcttaaaa aaaaaaaaaa aaaaaaaaaa
      781 aa
//
