LOCUS       NM_001037788            1283 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus serine/threonine/tyrosine interacting-like 1
            (Styxl1), mRNA.
ACCESSION   NM_001037788 XM_341057
VERSION     NM_001037788.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1283)
  AUTHORS   Banks,D.A., Dahal,A., McFarland,A.G., Flowers,B.M., Stephens,C.A.,
            Swack,B., Gugssa,A., Anderson,W.A. and Hinton,S.D.
  TITLE     MK-STYX Alters the Morphology of Primary Neurons, and Outgrowths in
            MK-STYX Overexpressing PC-12 Cells Develop a Neuronal Phenotype
  JOURNAL   Front Mol Biosci 4, 76 (2017)
   PUBMED   29250526
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1283)
  AUTHORS   Flowers,B.M., Rusnak,L.E., Wong,K.E., Banks,D.A., Munyikwa,M.R.,
            McFarland,A.G. and Hinton,S.D.
  TITLE     The pseudophosphatase MK-STYX induces neurite-like outgrowths in
            PC12 cells
  JOURNAL   PLoS One 9 (12), e114535 (2014)
   PUBMED   25479605
  REMARK    GeneRIF: data suggest that MK-STYX may be a regulator of RhoA
            signaling, and implicate this pseudophosphatase as a regulator of
            neuronal differentiation
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1283)
  AUTHORS   Niemi,N.M., Sacoman,J.L., Westrate,L.M., Gaither,L.A.,
            Lanning,N.J., Martin,K.R. and MacKeigan,J.P.
  TITLE     The pseudophosphatase MK-STYX physically and genetically interacts
            with the mitochondrial phosphatase PTPMT1
  JOURNAL   PLoS One 9 (4), e93896 (2014)
   PUBMED   24709986
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1283)
  AUTHORS   Barr,J.E., Munyikwa,M.R., Frazier,E.A. and Hinton,S.D.
  TITLE     The pseudophosphatase MK-STYX inhibits stress granule assembly
            independently of Ser149 phosphorylation of G3BP-1
  JOURNAL   FEBS J 280 (1), 273-284 (2013)
   PUBMED   23163895
REFERENCE   5  (bases 1 to 1283)
  AUTHORS   Niemi,N.M., Lanning,N.J., Klomp,J.A., Tait,S.W., Xu,Y.,
            Dykema,K.J., Murphy,L.O., Gaither,L.A., Xu,H.E., Furge,K.A.,
            Green,D.R. and MacKeigan,J.P.
  TITLE     MK-STYX, a catalytically inactive phosphatase regulating
            mitochondrially dependent apoptosis
  JOURNAL   Mol Cell Biol 31 (7), 1357-1368 (2011)
   PUBMED   21262771
REFERENCE   6  (bases 1 to 1283)
  AUTHORS   Hinton,S.D., Myers,M.P., Roggero,V.R., Allison,L.A. and Tonks,N.K.
  TITLE     The pseudophosphatase MK-STYX interacts with G3BP and decreases
            stress granule formation
  JOURNAL   Biochem J 427 (3), 349-357 (2010)
   PUBMED   20180778
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Dec 5, 2020 this sequence version replaced NM_001037788.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098678.1, SRR26360194.2024770.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                JAXUCZ010000012.1  26544195-26544223
            30-133              JAXUCZ010000012.1  26552382-26552485
            134-195             JAXUCZ010000012.1  26554346-26554407
            196-361             JAXUCZ010000012.1  26557698-26557863
            362-507             JAXUCZ010000012.1  26564174-26564319
            508-653             JAXUCZ010000012.1  26566012-26566157
            654-751             JAXUCZ010000012.1  26567622-26567719
            752-864             JAXUCZ010000012.1  26569677-26569789
            865-1283            JAXUCZ010000012.1  26575947-26576365
FEATURES             Location/Qualifiers
     source          1..1283
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..1283
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /note="serine/threonine/tyrosine interacting-like 1"
                     /db_xref="GeneID:360792"
                     /db_xref="RGD:1305845"
     exon            1..29
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
     exon            30..133
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..996
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /note="map kinase phosphatase-like protein MK-STYX"
                     /codon_start=1
                     /product="serine/threonine/tyrosine-interacting-like
                     protein 1"
                     /protein_id="NP_001032877.2"
                     /db_xref="GeneID:360792"
                     /db_xref="RGD:1305845"
                     /translation="MADLLFCEPTELYNILNQVSKLSRLAEPNYLCLLDVRSKRQYDE
                     SHVITARRVKKRDHQYLIPESVDLECVKYCIVYDSNTSSLELSIRPRYEEEEEEEEEE
                     KEGKEDDSELLPGPAVEFGQILIHFTRQPVYILRGGYECFSGLYHFFRTQKVIWMPQE
                     LDAFLPYPIEIVPGKVFLGKLSQACNAKMHKDLKIKAHVNISLETTPYFVGNVDKLLH
                     IKIEDTPDSILFPSFRHISHFIELHLKLRSVILVFSTRGISRSVAAVVAFLMHYNEET
                     LKRSWAHVKKCKTNMRPNRALVAQLLEWEKALHGEYLTDISEPIY"
     exon            134..195
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
     exon            196..361
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
     exon            362..507
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
     exon            508..653
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
     exon            654..751
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
     exon            752..864
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
     exon            865..1283
                     /gene="Styxl1"
                     /gene_synonym="Dusp24; RGD1305845"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagtacctt acaggaaccg ttaacccagg atggccgact tgcttttctg tgagccaaca
       61 gaactctata acatcttgaa tcaggtctcc aagctgtcca gattagctga gcccaactac
      121 ctctgtttac tggatgttcg atccaaaagg cagtatgatg agagccatgt gatcactgcc
      181 cgtagagtga agaagagaga tcatcagtac ctcatcccag agtctgtaga tctggagtgt
      241 gtgaagtact gcatcgtgta cgacagcaac accagttccc tggagctgag catacggccg
      301 cggtatgagg aggaagagga ggaagaggag gaagaaaaag agggcaagga ggacgactct
      361 gaactcttac ctggacctgc tgtggaattt ggacaaatcc tcatccactt tacccgccaa
      421 cctgtctata tcctcagagg gggctatgaa tgcttctctg gcttgtacca cttcttccgg
      481 acccagaagg tcatctggat gccccaggaa ctggatgcct tcctgccata cccaattgag
      541 atagttcctg gcaaagtctt cctgggcaaa ctcagtcagg cctgtaatgc taagatgcac
      601 aaggacttga aaattaaagc acatgtcaat atctccttgg agacaacacc ctattttgta
      661 ggcaatgtgg acaagctcct gcatatcaag attgaggata ctccagactc catacttttt
      721 ccctctttcc gccacatcag tcattttata gaacttcacc tcaagctccg atctgtgatt
      781 ctggtctttt ctacacgggg catcagccgc agtgttgctg ctgtggtggc cttcctcatg
      841 cattataatg aggagaccct gaagaggtcc tgggcccatg tgaagaaatg caaaaccaac
      901 atgcgtccga atagggcctt ggtggctcag ctgctggagt gggagaaagc cctccacggg
      961 gaatatctca cggacatctc tgagcctatc tactaacctt cgcccgtgac ccagccatgg
     1021 tctctgagga gtctgggttg ggacttttgg gggctgggag tctgggtttg gagtagtcct
     1081 ggagaagacc tttgctgtct ggaggttcat atctgcatct taagactgtt ctgttgttgt
     1141 tgttgttgtt gttgtttccc ccaatactga ggattgaacc tagagcagtg agtgcttctc
     1201 aaccttccta atgctgtggc tctttaatac agttcctcat gccatggtga ccttaaccat
     1261 aaagttatac cattgctact cca
//
