LOCUS       NM_001271250            3560 bp    mRNA    linear   ROD 19-APR-2019
DEFINITION  Rattus norvegicus syntaxin binding protein 5-like (Stxbp5l), mRNA.
ACCESSION   NM_001271250 XM_001070379 XM_002724717 XM_002724718 XM_002724719
            XM_221424
VERSION     NM_001271250.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3560)
  AUTHORS   Geerts CJ, Mancini R, Chen N, Koopmans FTW, Li KW, Smit AB, van
            Weering JRT, Verhage M and Groffen AJA.
  TITLE     Tomosyn associates with secretory vesicles in neurons through its
            N- and C-terminal domains
  JOURNAL   PLoS ONE 12 (7), e0180912 (2017)
   PUBMED   28746398
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3560)
  AUTHORS   Geerts CJ, Plomp JJ, Koopmans B, Loos M, van der Pijl EM, van der
            Valk MA, Verhage M and Groffen AJ.
  TITLE     Tomosyn-2 is required for normal motor performance in mice and
            sustains neurotransmission at motor endplates
  JOURNAL   Brain Struct Funct 220 (4), 1971-1982 (2015)
   PUBMED   24744148
REFERENCE   3  (bases 1 to 3560)
  AUTHORS   Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL,
            Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP,
            Thurmond DC and Attie AD.
  TITLE     Positional cloning of a type 2 diabetes quantitative trait locus;
            tomosyn-2, a negative regulator of insulin secretion
  JOURNAL   PLoS Genet. 7 (10), e1002323 (2011)
   PUBMED   21998599
REFERENCE   4  (bases 1 to 3560)
  AUTHORS   Williams AL, Bielopolski N, Meroz D, Lam AD, Passmore DR, Ben-Tal
            N, Ernst SA, Ashery U and Stuenkel EL.
  TITLE     Structural and functional analysis of tomosyn identifies domains
            important in exocytotic regulation
  JOURNAL   J. Biol. Chem. 286 (16), 14542-14553 (2011)
   PUBMED   21330375
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AAHX01069638.1, AAHX01069640.1, AAHX01069643.1, AAHX01069644.1,
            AAHX01069647.1, AAHX01069648.1, AAHX01069650.1 and AAHX01069653.1.
            
            [WARNING] On Apr 9, 2024 this sequence was replaced by
            NM_001271250.2.
            
            On or before Sep 12, 2012 this sequence version replaced
            XM_221424.6, XM_001070379.2, XM_002724717.1, XM_002724718.1,
            XM_002724719.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the genome
            assembly. The genomic coordinates used for the transcript record
            were based on alignments.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               AAHX01069638.1     14471-14658
            189-286             AAHX01069640.1     8192-8289
            287-368             AAHX01069643.1     16963-17044         c
            369-469             AAHX01069643.1     6423-6523           c
            470-604             AAHX01069644.1     11216-11350
            605-668             AAHX01069644.1     13813-13876
            669-752             AAHX01069647.1     3744-3827
            753-876             AAHX01069647.1     9440-9563
            877-955             AAHX01069647.1     16604-16682
            956-1110            AAHX01069647.1     22401-22555
            1111-1183           AAHX01069647.1     27533-27605
            1184-1331           AAHX01069648.1     26257-26404
            1332-1399           AAHX01069648.1     27527-27594
            1400-1440           AAHX01069648.1     30411-30451
            1441-1658           AAHX01069648.1     32546-32763
            1659-1831           AAHX01069648.1     35847-36019
            1832-1957           AAHX01069650.1     1735-1860
            1958-2109           AAHX01069650.1     12415-12566
            2110-2181           AAHX01069650.1     14368-14439
            2182-2247           AAHX01069650.1     23777-23842
            2248-2418           AAHX01069653.1     8971-9141
            2419-2658           AAHX01069653.1     11259-11498
            2659-3019           AAHX01069653.1     16635-16995
            3020-3185           AAHX01069653.1     20626-20791
            3186-3297           AAHX01069653.1     28971-29082
            3298-3518           AAHX01069653.1     31408-31628
            3519-3560           AAHX01069653.1     31770-31811
FEATURES             Location/Qualifiers
     source          1..3560
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..3560
                     /gene="Stxbp5l"
                     /note="syntaxin binding protein 5-like"
                     /db_xref="GeneID:288080"
                     /db_xref="RGD:1311561"
     CDS             3..3560
                     /gene="Stxbp5l"
                     /codon_start=1
                     /product="syntaxin-binding protein 5-like"
                     /protein_id="NP_001258179.1"
                     /db_xref="GeneID:288080"
                     /db_xref="RGD:1311561"
                     /translation="MKKFNFRKVLDGLTASSPGSGSSSGSNSGGAGSGSVHPGGTAGV
                     LREGIQESLISECFQICKTVRHGFPYQPTALAFDPVQKILAIGTRTGAIRILGRPGVD
                     CYCQHESGAAVLQLQFLINEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYC
                     HLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPR
                     DEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLW
                     NLKSPSRPFQTTVPHGKSQREGRKSESCKPILKVEYKTCRNSEPFIIFSGGLSYDKAC
                     RRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVAVLLEKDLIVVDLTQ
                     TNFPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIGVKHKKQGYSNKEWPVSGG
                     AWNLGAQTYPEIIITGHADGTIKFWDASAMTLQMLYKLKTSKVFEKQKVGDGKQTCEI
                     VEEDPFAVQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITAEIVSLEVRLQCDVEDII
                     TPEPETSPPFPDLSSQLPSSRSLSGSTNTVSSEGVTKDSIPCLSVKTRPVRMPPGYQA
                     DLVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCTGLVVVDFIQKTVLLSMGTIDLYR
                     SSDLYQRQPRSPRKNRQFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLEL
                     ERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSAACMEI
                     SLPVTTEETRENSYNRSRSSSISSIDKDSKEAITALYFMESFARKNDSTVSPCLFVGT
                     SLGMVILISLNLPSSDEQRFTEPVVVLPSGTFLSLKGAVLTFSCMDRTGNLMQPPYEV
                     WRDPNNTDENEKTWKRKLVMNYSSSSQEMGDHQYTIICSEKQAKVFSLPSQTCLYVHN
                     ITETSFILQADVVVMCNSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDMRIARTF
                     CFTNEGQALYLVSPTEIQRLTYSQEMCDNIQDMLGDLFTPIETPEAQNRGFLKGLFGG
                     SGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERG
                     QRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF"
ORIGIN      
        1 aaatgaagaa gtttaatttc cgaaaagttt tggatggctt aactgcctct tcccccggca
       61 gtggtagcag cagcggcagt aatagtggtg gggctggaag tggctccgtc catcctggag
      121 ggactgcagg ggttctgaga gaggggatcc aggaaagcct catctccgag tgtttccaga
      181 tttgcaagac agttcggcac ggttttccct atcagcccac agcattggcc tttgatccag
      241 tccagaaaat cctggctatt ggaacgagaa caggtgctat acgaatactt gggaggcctg
      301 gtgttgactg ttactgccaa catgagagtg gggcggctgt cttgcagctc caattcctga
      361 tcaatgaggg cgctttggtc agtgcgagtt cagatgacac acttcatttg tggaatctga
      421 gacagaaaag gccggctatt ctccattctc ttaagtttaa cagagaacga attacttact
      481 gtcatctacc tttccagagt aaatggctct atgttggaac agaaagagga aatacacata
      541 ttgtaaatat tgaatctttc attctttctg gatatgtcat catgtggaac aaggcaattg
      601 agctctccac caagactcat ccaggcccag ttgtacatct aagtgatagc ccaagagatg
      661 aaggaaaact gttaataggt tatgaaaatg gcactgtggt attctgggac ttgaaatcta
      721 aaagagcaga actgagagtt tattatgatg aggctattca ttcaattgat tggcatcatg
      781 agggcaaaca attcatgtgc agccactcag atggtagctt gactttatgg aacctgaaaa
      841 gcccaagtcg ccctttccaa accacagttc cacatggaaa aagtcaaaga gaaggaagaa
      901 agtctgaatc ttgtaaacct attctgaaag tagagtacaa aacgtgcagg aacagtgaac
      961 catttataat attctctggt gggttgtcat atgacaaagc ttgcagaaga ccaagtttaa
     1021 ccatcatgca tgggaaagca attacagtac ttgaaatgga tcatcctatt gttgaatttc
     1081 taactttatg tgaaacgccc tatcccaatg agtttcaaga accctatgct gttgcagtac
     1141 ttctagagaa agatctcatc gtagttgatc taacacaaac caattttcca atctttgaaa
     1201 atccatatcc aatggacatt catgagtcac cagttacatg cacagcatat tttgccgatt
     1261 gccctccaga tttgattcta gtactctatt ctataggagt caagcataaa aaacaaggat
     1321 acagtaataa ggaatggcca gtaagtggag gagcttggaa tcttggagca caaacgtatc
     1381 cagaaattat tattactggt catgctgatg gaacaataaa attttgggat gcttcagcaa
     1441 tgacactgca gatgttgtac aagctaaaaa cttcaaaagt atttgaaaag cagaaggtgg
     1501 gagatggcaa acagacgtgt gagattgtag aagaagatcc ctttgctgtt cagatgattt
     1561 actggtgtcc agagagcaga atattttgtg tatctggggt ctctgcatat gtcataattt
     1621 ataaattcag cagacatgaa atcacagcag aaatagtgtc attagaggta cgacttcagt
     1681 gcgatgttga agacattatt actcctgagc cagaaacaag tcctccattt ccagatctct
     1741 cctctcaact tccttcttca aggagtcttt ctggaagcac taatactgtg tctagtgaag
     1801 gcgtgacgaa ggacagcatc ccatgcctca gtgttaaaac acggccagtg cgcatgccgc
     1861 cgggctatca agcggatctt gttattcagt tggtgtgggt agatggcgag ccgcctcagc
     1921 agatcaccag cctcgctgtg agctcggcat acggaatagt tgcatttgga aactgcacgg
     1981 ggttggttgt ggtagatttc atccagaaga cagtactgtt aagcatgggg accattgacc
     2041 tctatagatc aagtgacctg taccagcgac agccccggtc tcctcgaaaa aacaggcagt
     2101 tcattgcaga caacttttgc atgcgtgggc tgtctaactt ttatcctgat ttaacgaaac
     2161 ggatccgtac ttcctatcag agcttaacag agctgaatga tagtccagtt cccttggaac
     2221 ttgagcggtg caagtctccc acttcagacc atgtaaatgg acactgcaca agtccaacct
     2281 ctcagagttg cagttctgga aaacgtcttt ccagtgctga tgtttcaaaa gtaaatcgct
     2341 ggggtcctgg aagaccacca tttagaaagg cacagtcagc tgcttgcatg gagatatctt
     2401 taccagttac aactgaagaa acccgagaga actcctataa ccgctccagg agctctagca
     2461 tctccagtat tgacaaggat tctaaagaag caattacagc tttgtacttc atggaatcct
     2521 ttgcacggaa aaatgactct accgtgtccc cttgtctgtt tgttggaact agtctgggaa
     2581 tggtaatact catctcccta aatctaccat catcagatga acaaaggttt acagagccgg
     2641 tggtggtatt gccaagtggt acattcctct cactgaaagg agctgtgcta acattttcct
     2701 gcatggacag aactggcaat ttaatgcagc ctccatatga ggtatggagg gatcccaaca
     2761 acacagatga aaatgaaaaa acctggaaaa ggaaattggt catgaactac tcctcttcat
     2821 cccaagaaat gggagaccat cagtatacga taatctgctc agaaaaacaa gccaaagtct
     2881 tctcactgcc gtcccagacc tgcctttatg ttcacaacat cacagagacg tcattcatat
     2941 tgcaagcaga tgtggtggtc atgtgcaaca gtgcctgcct ggcctgcttt tgtgcgaatg
     3001 ggcatatcat gataatgagc ttacctagcc ttcgcccaat gttggatgtt aattatttgc
     3061 cactgacaga catgagaata gcacggacat tttgttttac taatgaagga caggcattat
     3121 accttgtctc cccaactgaa attcaacggt taacatatag ccaagaaatg tgtgataata
     3181 ttcaggacat gttaggcgat ttgtttactc caatagagac accagaagcc caaaatagag
     3241 gctttctcaa gggactgttt ggtggaagtg gacagacatt tgacagagaa gaactctttg
     3301 gggaagcctc agcaggaaaa gcatctcgca gcctcgcaca gcacattcct ggaccgggca
     3361 gcatagaagg gatgaagggc gctgctggcg gggtgatggg agagctaacg cgagcccgga
     3421 ttgcacttga tgagagaggg cagcgcctgg gtgagctgga ggagaagact gcaggcatga
     3481 tgaccagtgc agaagcattt tccaagcacg cacacgagct aatgctgaaa tataaggaca
     3541 agaaatggta ccagttctaa
//
