LOCUS       NM_001415095            6043 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus syntaxin binding protein 4 (Stxbp4), mRNA.
ACCESSION   NM_001415095 XM_006247128
VERSION     NM_001415095.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6043)
  AUTHORS   Li,Y., Peart,M.J. and Prives,C.
  TITLE     Stxbp4 regulates DeltaNp63 stability by suppression of
            RACK1-dependent degradation
  JOURNAL   Mol Cell Biol 29 (14), 3953-3963 (2009)
   PUBMED   19451233
REFERENCE   2  (bases 1 to 6043)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 6043)
  AUTHORS   Trost,M., English,L., Lemieux,S., Courcelles,M., Desjardins,M. and
            Thibault,P.
  TITLE     The phagosomal proteome in interferon-gamma-activated macrophages
  JOURNAL   Immunity 30 (1), 143-154 (2009)
   PUBMED   19144319
REFERENCE   4  (bases 1 to 6043)
  AUTHORS   Watson,R.T. and Pessin,J.E.
  TITLE     GLUT4 translocation: the last 200 nanometers
  JOURNAL   Cell Signal 19 (11), 2209-2217 (2007)
   PUBMED   17629673
  REMARK    Review article
REFERENCE   5  (bases 1 to 6043)
  AUTHORS   Saito,T., Okada,S., Yamada,E., Ohshima,K., Shimizu,H.,
            Shimomura,K., Sato,M., Pessin,J.E. and Mori,M.
  TITLE     Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate
            insulin secretion in the pancreatic beta HC-9 cell
  JOURNAL   J Biol Chem 278 (38), 36718-36725 (2003)
   PUBMED   12855681
REFERENCE   6  (bases 1 to 6043)
  AUTHORS   Min,J., Okada,S., Kanzaki,M., Elmendorf,J.S., Coker,K.J.,
            Ceresa,B.P., Syu,L.J., Noda,Y., Saltiel,A.R. and Pessin,J.E.
  TITLE     Synip: a novel insulin-regulated syntaxin 4-binding protein
            mediating GLUT4 translocation in adipocytes
  JOURNAL   Mol Cell 3 (6), 751-760 (1999)
   PUBMED   10394363
  REMARK    Erratum:[Mol Cell 1999 Jul;4(1):following 142]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Dec 21, 2022 this sequence version replaced XM_006247128.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.25333.1,
                                           SRR26360176.873095.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                JAXUCZ010000010.1  75955688-75955737   c
            51-174              JAXUCZ010000010.1  75943371-75943494   c
            175-296             JAXUCZ010000010.1  75942893-75943014   c
            297-429             JAXUCZ010000010.1  75940773-75940905   c
            430-536             JAXUCZ010000010.1  75920421-75920527   c
            537-753             JAXUCZ010000010.1  75920043-75920259   c
            754-832             JAXUCZ010000010.1  75919011-75919089   c
            833-927             JAXUCZ010000010.1  75911840-75911934   c
            928-1024            JAXUCZ010000010.1  75907056-75907152   c
            1025-1116           JAXUCZ010000010.1  75903641-75903732   c
            1117-1206           JAXUCZ010000010.1  75892088-75892177   c
            1207-1272           JAXUCZ010000010.1  75886654-75886719   c
            1273-1449           JAXUCZ010000010.1  75866488-75866664   c
            1450-1566           JAXUCZ010000010.1  75860080-75860196   c
            1567-1616           JAXUCZ010000010.1  75858549-75858598   c
            1617-1750           JAXUCZ010000010.1  75856403-75856536   c
            1751-1808           JAXUCZ010000010.1  75820874-75820931   c
            1809-6043           JAXUCZ010000010.1  75798938-75803172   c
FEATURES             Location/Qualifiers
     source          1..6043
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..6043
                     /gene="Stxbp4"
                     /note="syntaxin binding protein 4"
                     /db_xref="GeneID:303443"
                     /db_xref="RGD:1307903"
     exon            1..50
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            51..174
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            175..296
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..1923
                     /gene="Stxbp4"
                     /codon_start=1
                     /product="syntaxin-binding protein 4"
                     /protein_id="NP_001402024.1"
                     /db_xref="GeneID:303443"
                     /db_xref="RGD:1307903"
                     /translation="MDIGTSSARSSSPLERDPAFRVITVAKETGLGLKILGGIDRNEG
                     PLVYIHEVTPGGDCYKDGRLKPGDQLVSINKESMIGVSFEEAKNILTRAKLRWESPLE
                     IAFIRQKSYCGHPGNICCQSPPVSEDCEPQTSAFNLLSSPAGTLLPKTSSTPRTQDSI
                     LPSCTVIQTQPEHSQAGLAPVPSLNNRPTDTSNADIAPAWTDDASGPQGKISLNPSAR
                     LKAEKLEMALNYLGIQPTKEQHEALRQQVQADSEGTVSFGDFVQVARNLFCLQLDEVN
                     VGDHELPSVLDSQLLPCGSLEADEVGRLRQERNAALEERDALKEKLLESEKHRKQLIE
                     ELQNVKQEAKAVAEETRALRSRIHLAEAAQRQARGMEMDYEEVIRLLEAEVSELKARL
                     ADYSDQNKESVQDLRKRVTVLDCQLRKSEMARKTFKSSTERLLRFVEAIQEVLLDSCA
                     PLSNLSERRAVLASQTSLPLLGRNGRNFPAPLLLESKELLRSVRAVLDMDCLPYGWEE
                     AYTADGIKYFINHVTQTTSWIHPMMSVLNLSCAEESEEDCPRELREPKS"
     exon            297..429
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            430..536
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            537..753
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            754..832
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            833..927
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1024
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1116
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1206
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1272
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1449
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1566
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..1616
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1750
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1751..1808
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..6043
                     /gene="Stxbp4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agattccaca ggtagcagtc gcgctacgga ggccgggtgg cccgaagagg gaaacccgtg
       61 aggtggagta gcatgagctg gagccataca gaatctgcag gaagaccctc gggggagtcg
      121 gggggacacg gctttctgct ttcttcacgt ggactgtgta actatttttc tgcttctgag
      181 gaaaagaata tttagactct ccaaggtctt ccttcacata gctgttaaat ccaaggcaac
      241 tgtggaagca tggatattgg tacatcttct gcacggtcct ccagcccact tgaaagggat
      301 cctgcctttc gggtgattac agtggctaag gaaacaggtc taggtctgaa gatcctaggc
      361 ggcattgata ggaatgaagg accattggtg tatattcacg aagtcactcc tggaggcgac
      421 tgttacaagg atggacgttt gaagccagga gatcagcttg tctccataaa caaggaatct
      481 atgattggtg tatcatttga agaagcaaaa aacatactta ccagagccaa gttgaggtgg
      541 gaatctccgt tggagatagc atttatcaga cagaagtctt actgtggtca tccaggaaac
      601 atttgctgtc agtccccacc agtgtcagaa gactgtgaac ctcaaacctc agcatttaat
      661 cttctttcct ctcccgctgg aacactactt ccaaagactt catccactcc caggactcag
      721 gactccattt taccctcctg tacagtaatt cagactcaac ctgagcacag tcaagcaggg
      781 cttgctccag ttccttcttt gaacaaccgc cctacagaca catccaatgc agacattgct
      841 ccagcctgga ctgatgacgc ttctggacca caaggaaaga tttccctaaa tccttctgct
      901 cgccttaagg cagagaaact ggaaatggct ctcaattacc tcggtataca gccaacaaag
      961 gaacagcatg aagccctgag acagcaagtc caggccgact cagaggggac tgtgtctttt
     1021 ggggatttcg tccaggttgc cagaaatttg ttctgcttgc agttggatga agtaaatgtt
     1081 ggtgaccatg aactccccag cgtcttggac tcacagcttc tcccctgtgg ttctctagaa
     1141 gcagatgaag tgggaagact gagacaagaa agaaatgctg ctctggaaga acgggatgcg
     1201 cttaaggaga aattactcga atcagagaag cacaggaaac agttgataga agaactccag
     1261 aatgtgaaac aggaagccaa agccgtagcc gaggaaacac gagctctgcg aagccggatt
     1321 catcttgccg aagctgcaca gaggcaggca cgtgggatgg aaatggatta tgaagaggtg
     1381 atccgtctgc tagaggctga ggtctcagaa ctaaaggccc ggctcgctga ttattctgac
     1441 caaaataaag aaagtgtcca agacttgaga aagagagtca cagttcttga ctgccaattg
     1501 cgaaaatcag aaatggctcg gaaaacattt aagtcatcca ctgaaaggct ccttcgtttt
     1561 gtagaggcta ttcaagaagt acttttggac agttgtgctc ctttatcaaa tttaagtgaa
     1621 agaagagctg tgcttgcctc tcagacctcg cttccgctgc tgggaaggaa cggacgtaac
     1681 ttcccagcac ccctgcttct ggaatccaag gaacttctta ggtctgtccg tgccgtactt
     1741 gatatggact gcttacctta cgggtgggag gaagcttaca cagcagatgg gatcaagtac
     1801 ttcatcaacc atgtgacaca gaccacgtcc tggatccacc ccatgatgag tgtcctgaac
     1861 ctgtcctgcg cagaggagag tgaagaggac tgtcccagag aactaaggga accgaaaagc
     1921 tgatgagttt ccacgggcaa cggagctcca gagacttccg acttttcaat atatatgcac
     1981 aaccagacga acgacaccac aactgagaca caggactcca gcacatgcta ccaggccggg
     2041 tgtcgagttg aaaccgtggt atttttgtgt acatgctaag gatcagttgc cactgtagta
     2101 gttgtttgaa aataatctag tcatatatag tcagatttta tatgcatatg tcttctcatt
     2161 tatacttaga tctttataat tcaatgtata gttccttgtt tggtataaga tacaatggtt
     2221 cgtacagcaa cactttatat tgaaaagtta tatgaacata gcgaacattc ttgataactc
     2281 cccctctctc ctcacagcgt aggaaagaat tctgaggaag ctaggggagg gcgcccaacc
     2341 ctatcccatt agctgctgat tgcaactctt gggttttggg gtgttttttt ttttaccagt
     2401 gcctcatagg acaccacgtg acatatcatt aggaaacttc tatcgtttat aaaaagcttt
     2461 caaacctcgt cttacttaaa ccaaacagca cggctgttcc acagggcatt tctactcacg
     2521 gcttcagctg gagagacagt ggttccaaaa gacagagcgt gcagtgccgg ggatgggact
     2581 cacaccttac cttccgattc cgtgcccagg ctcccttgcc ctgctcccta ctgacctcac
     2641 agagggagat ctcggcccag gagagcatcc actttctgtt gacgcagctg ggtccacagc
     2701 tgcgcattcc acacctcaga gccaaacatt gcctcttcat aaccccagtc tcttccttct
     2761 gtggccccat ccccaccccc accactaccc gtagacactc accaagcaag gcactgctct
     2821 gcgacttttc agtggacttt gttccgtgac tggattttct agaatagaga cactggctca
     2881 tggcagtggt ttgccatgct tgggtgccat ggccagtggg agcatctgag gagagctgac
     2941 aggagaaagg tatcttttta aatactgctg gagttgcctg taaaagggtg gaggccagga
     3001 gccaagcaaa gcagcccagc atcacttagg taagcatgga gctcccaaga gcacagtgca
     3061 agcatcttta cttaaagcca ctttataaat aagccactga gttcctgcag tgaagtagca
     3121 cctatggcgg catcagacac tagcgcctac atgttctgca gagttttacc tcatatatgg
     3181 aatgtatatg gagaatacat gtgggcacgg tgctcaccca taccccttag tacatttaag
     3241 atttaggatt taagttgaat ccacttagga ttcatgtttg ccgtcatgag gaagaacata
     3301 aagccaaata cagactgaca aggagacttt aaccccagga aagacagagt ggctggagca
     3361 aatgtaggcc tctcctcaca gctctctgga tcttaggacg cttcgaagag gatgattggg
     3421 gtgggggtgg ggggcagctt tgagagcagc tgcagcggga gctgtttcct caagtcccag
     3481 agaagtgaag aggcacccac acacttttat gagaggagtg aaccagcaca ctccttttag
     3541 gagatcgccc cctgccccca ttgcagtgtc ctcccttgtt tgtgagggag ctgacatggg
     3601 accctgaagc atgcagtctg tgtgtgttcg tgtatgtgtg gcactcacag cctctctgct
     3661 gcttatacca agttcctccc tgtttctacc aaatacataa tcaaacgacc tagaaatgca
     3721 tagcgctatt tactgagcac tgtaccgtac actgcaatgt acaatgaaca acttttggga
     3781 ggcttcttgg gatagcctct ccctgtgtat accatcctgg ccttgagttc gcaatccccc
     3841 tgcttcagcc tcccaagtac tggtatttca gcaacaagcc aagaagcttc ccaaagtgat
     3901 cccaattata tgaagaagcc gaggtttaga gagaagtggt cactgcccaa ggatcccgcc
     3961 gtgcctatgt gttgatgctg gacctgaagg caagtcttag accccagggc ttccttaaac
     4021 caggggtaga gactcctgga tttagtcagc cctgcaagac tccagttttc agtcatgagg
     4081 aacttcctgg ttcatgagaa aggcattccc caggagaaaa tagcatccat ccagttcctc
     4141 tgcatctgaa cttctcctgt gactgcagct aaggacgttc accctgaatt agctgagtct
     4201 ggtgaacaat cattgagaac tacgctttag tctccatgac ctccagaccc acagataaag
     4261 gacagatgct cagagaatct ccagaggagg gctcagtatg aatgcttctc cggtgcagac
     4321 agaaccctgg gttacttgtg gggaagtgga tgttctttaa gttaccttat ctctgtcact
     4381 atagctatcc ataaaaaaat gcccctccgc tgacccacca ctcagatctg ggccacagga
     4441 actgaatgtg gtcacatccc tcccaatgtg tgtcccagag gcattggcca gcagctccct
     4501 tcatagagtg acaaggggct ttcccttgga atgctcgtta gctaccagca ttgtggttag
     4561 cactctggtc cagggcaaag tagggcaata gctaaccatt ccttgggatg ttttaaaaat
     4621 aaaaacgatc ttgaaagtca gcagtagtaa ctttttaact cctaaaacgt aaaaataatt
     4681 tattttcctt tcaaaaaaac agatcaaggt tctgtggaaa taaattgagt ttgataaata
     4741 gcccatctaa ctttctagaa gcttccatca ccaatattgc agtaaatatt ttcaatcgag
     4801 ggcaagcatg ccacccttaa acagctcacc tttgagttag tatcttacgg tcatcttttc
     4861 atagccatat aggcatcctg atgcactttt aagtctctgc ttaagctatc tcgtcccaga
     4921 atgcccttcg tcagttgttc agcaacttat taaagaaatc ttagactact ttaagttcct
     4981 tcctgtaaca gtgtcatggc gagcatttgt gtatttgtta aaaccttttc ttcaagtatc
     5041 catgcactca gatactgacg tcggtagagt gaatactttt gtaagccact gtgtcagaag
     5101 tacagtcaaa gttctgtcac tgaaccaaga gcttctccag ccctgcgtaa aaacctggat
     5161 gttttaatca cttcatttta gcatctcttt agcatcggag actggcttgc tgtatgggag
     5221 agagtctggc agtgactaat tcagtgttcc aaacatggca ttcctctcac tgctttctgc
     5281 tttacatgta atgatgataa ggaattgctt caaaatcagc acagagagca aacttatgaa
     5341 tacaatacaa gagccaccat ttctccatct gtggcatacg tcctcgtgcc cacacgattc
     5401 aactcagcac acatgacctg agcacctact gtgtgcctgg ccgtgcacag tgtgatagct
     5461 gtgaatagta caaatttcca aatcagagag ctcagtttct tgatatttct acacggacac
     5521 actgtacagg gtaagaagtt aaggatttgt ttcctaagaa tcccttaaat ttgaataatt
     5581 atggaaaaca ttgacacccc ccaccttggc tagaataggg ggagaaggaa cgtgctggaa
     5641 gaggctctcc aataacaaat gaaaggcagc tgtcaaaata gactcaaata gcacactcat
     5701 aaactgcttg cgcaatcaga aaatattatc ctttttctag ggagaaatag gacatttctc
     5761 tacagtaagc aaaatgtaac tttttgaagg gtcaatacac ttgacatttt tatgttactt
     5821 atacagacag aactgaacaa acattaatgt ggctttcaca gtcatgggta taattttcag
     5881 gatgatgaaa agcacagact atgcccgtgg aatttaaaga attaaacaga atgtgcctgt
     5941 gaaacatgac tttagacatg tactacatga gatggtttag ccatggctgt tcacatgtaa
     6001 tatcactgta tcagtaaagc gatttaataa acactcgaca cag
//
