LOCUS       NM_021869               2103 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus syntaxin 7 (Stx7), mRNA.
ACCESSION   NM_021869
VERSION     NM_021869.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2103)
  AUTHORS   Wilhelm,B.G., Mandad,S., Truckenbrodt,S., Krohnert,K., Schafer,C.,
            Rammner,B., Koo,S.J., Classen,G.A., Krauss,M., Haucke,V., Urlaub,H.
            and Rizzoli,S.O.
  TITLE     Composition of isolated synaptic boutons reveals the amounts of
            vesicle trafficking proteins
  JOURNAL   Science 344 (6187), 1023-1028 (2014)
   PUBMED   24876496
REFERENCE   2  (bases 1 to 2103)
  AUTHORS   Pirooz,S.D., He,S., Zhang,T., Zhang,X., Zhao,Z., Oh,S.,
            O'Connell,D., Khalilzadeh,P., Amini-Bavil-Olyaee,S., Farzan,M. and
            Liang,C.
  TITLE     UVRAG is required for virus entry through combinatorial interaction
            with the class C-Vps complex and SNAREs
  JOURNAL   Proc Natl Acad Sci U S A 111 (7), 2716-2721 (2014)
   PUBMED   24550300
REFERENCE   3  (bases 1 to 2103)
  AUTHORS   Pattu,V., Qu,B., Marshall,M., Becherer,U., Junker,C., Matti,U.,
            Schwarz,E.C., Krause,E., Hoth,M. and Rettig,J.
  TITLE     Syntaxin7 is required for lytic granule release from cytotoxic T
            lymphocytes
  JOURNAL   Traffic 12 (7), 890-901 (2011)
   PUBMED   21438968
REFERENCE   4  (bases 1 to 2103)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   5  (bases 1 to 2103)
  AUTHORS   Xie,L.X., Calafat,J., Janssen,H., de la Iglesia-Vicente,J. and
            Mollinedo,F.
  TITLE     Intracellular location of syntaxin 7 in human neutrophils
  JOURNAL   Immunol Lett 129 (2), 72-77 (2010)
   PUBMED   20170677
REFERENCE   6  (bases 1 to 2103)
  AUTHORS   Richardson,S.C., Winistorfer,S.C., Poupon,V., Luzio,J.P. and
            Piper,R.C.
  TITLE     Mammalian late vacuole protein sorting orthologues participate in
            early endosomal fusion and interact with the cytoskeleton
  JOURNAL   Mol Biol Cell 15 (3), 1197-1210 (2004)
   PUBMED   14668490
REFERENCE   7  (bases 1 to 2103)
  AUTHORS   Antonin,W., Fasshauer,D., Becker,S., Jahn,R. and Schneider,T.R.
  TITLE     Crystal structure of the endosomal SNARE complex reveals common
            structural principles of all SNAREs
  JOURNAL   Nat Struct Biol 9 (2), 107-111 (2002)
   PUBMED   11786915
  REMARK    GeneRIF: Crystal structure of the endosomal SNARE complex reveals
            common structural principles of all SNAREs
REFERENCE   8  (bases 1 to 2103)
  AUTHORS   Antonin,W., Holroyd,C., Fasshauer,D., Pabst,S., Von Mollard,G.F.
            and Jahn,R.
  TITLE     A SNARE complex mediating fusion of late endosomes defines
            conserved properties of SNARE structure and function
  JOURNAL   EMBO J 19 (23), 6453-6464 (2000)
   PUBMED   11101518
REFERENCE   9  (bases 1 to 2103)
  AUTHORS   Prekeris,R., Yang,B., Oorschot,V., Klumperman,J. and Scheller,R.H.
  TITLE     Differential roles of syntaxin 7 and syntaxin 8 in endosomal
            trafficking
  JOURNAL   Mol Biol Cell 10 (11), 3891-3908 (1999)
   PUBMED   10564279
REFERENCE   10 (bases 1 to 2103)
  AUTHORS   Wong,S.H., Xu,Y., Zhang,T. and Hong,W.
  TITLE     Syntaxin 7, a novel syntaxin member associated with the early
            endosomal compartment
  JOURNAL   J Biol Chem 273 (1), 375-380 (1998)
   PUBMED   9417091
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085737.1.
            
            On Nov 15, 2004 this sequence version replaced NM_021869.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: AF031430.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMD00132261,
                                    SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2103
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     gene            1..2103
                     /gene="Stx7"
                     /note="syntaxin 7"
                     /db_xref="GeneID:60466"
                     /db_xref="RGD:619747"
     exon            1..31
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     exon            32..181
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..882
                     /gene="Stx7"
                     /note="syntaxin-7-like"
                     /codon_start=1
                     /product="syntaxin-7"
                     /protein_id="NP_068641.2"
                     /db_xref="GeneID:60466"
                     /db_xref="RGD:619747"
                     /translation="MSYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQD
                     TPELRQQLQQEQQYTNQLAKETDKYIKEFGFLPTTPSEQRQRKIQKDRLVAEFTTALT
                     NFQKVQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNFVSWESQTQPQVQVQDEEI
                     TEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVESAEVHVQ
                     QANQQLSRAANYQRKSRKTLCIIILILVVGIVIIFFIVWGLKG"
     exon            182..251
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     exon            252..345
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     exon            346..483
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     exon            484..536
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     exon            537..633
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     exon            634..706
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     exon            707..789
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
     exon            790..2078
                     /gene="Stx7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagctggag gtgacagagg aagccaacga ggtgactcct agaaaacccg acagcctgct
       61 tgcatctgat gaaatcggcc agtcatccag ccagccatgt cttacactcc ggggattggt
      121 ggggaccctg cccagctggc gcaacgcatc tcctctaaca tccaaaagat cacacagtgc
      181 tccgcggaaa tacaaaggac tctgaatcaa ctgggaacac ctcaggatac accggagttg
      241 aggcaacagc tgcagcagga gcagcagtat actaaccaac ttgcgaaaga aacagataag
      301 tacattaagg agtttggctt tctgcccacc acccccagtg aacagcgtca aaggaagata
      361 cagaaagacc gattggtggc agaattcacc acagcgctaa caaactttca gaaagtgcag
      421 aggcaagctg ctgagagaga gaaagagttc gtggcccgag tgcgagccag ttccagagta
      481 tcgggtggct ttcctgaaga cagctcaaaa gagaagaatt ttgtatcttg ggaaagccaa
      541 acacagcctc aagtgcaagt ccaagatgaa gaaatcacag aggatgacct ccggctcatt
      601 catgagagag agtcttcaat cagacagctg gaagctgaca ttatggacat taacgaaata
      661 ttcaaagact tggggatgat gattcatgaa caaggagatg ttattgacag catagaagcc
      721 aatgtagaaa gtgcggaagt tcacgtacag caggcaaacc agcagctgtc aagagcggca
      781 aattatcagc gcaaatccag aaaaaccctc tgcatcatca ttttaatcct ggtggtcgga
      841 atcgtgatca tcttcttcat cgtatggggt ctgaaaggct gagaccgacc gaaggcgcgg
      901 acgactgcat gatgttatca gcgagacgta ggcaggctct cgggatcact ttcttttgtc
      961 gatgttctga cgctgttgtg taaaagatgg ctccgcactt cgtcgttttt accagggggt
     1021 tgtggggggg tgggtgttct tttggattca atctgatatt ttctaatacc caagtttttt
     1081 aaaattccct ttgctggccc aatttccctg ctttttagtc caacaactgt tgggtttttt
     1141 gctcacgttg tatatgccct tcatttataa tttatttata ttgtttaact tttggggaat
     1201 tatctgattg gcatgtgtgc tctgcctaca cctctgtcac tgtgtaaccc gtgtaacatg
     1261 attgtgctat cttattaaaa aaaaatccga gtttaagttt catttgtcca gtaaatgttc
     1321 tcagtaggca aaccctagca gccccatctg tgggacattt tatcccctgt ggtccagggc
     1381 agtgcagatc attattgctc tgccattatt ggatggctct catcatccct gaataaaatc
     1441 agtgaatctc ttccctatgt gtatatatgc atttgctgca gattgcatca taaagatagt
     1501 gaggatagat tgtttttaat gtggactatt taatccacta catactaagg gcagaagcgt
     1561 ctgaaaaacc cataccaatg tctgttctgt ttagatgcta aagatgccag tttcgtactg
     1621 cacggaacca cttttcccac acggtcttgt tttatttggc cattagttac tttcccttgt
     1681 gtccctcaga acactcatta gacatgtatc tttgggtccc gtcttcgcaa agtaatgttc
     1741 ctacaattac agatttggga tttcattttt atacttaaat ttaatactta aatgttaaga
     1801 gttcgtttag atgccacttt ttttcttaaa accattcttc attcaaataa gaatcagatg
     1861 tctgccaatg aactcacttg tctttttgaa tcaatgtttt aatgcactaa tatgaatgct
     1921 gtaaaagggg ctatcttaga ttatcgcttg tgttttataa tgttcttaca cagccgtctg
     1981 ctaatgctgg cactgtttaa tgtggctctg aaacctttaa atgggaacaa gtgaaatatt
     2041 aacaatggaa gcagaataaa ggtgattctg gacatgtcaa aaaaaaaaaa aaaaaaaaaa
     2101 aaa
//
