LOCUS       NM_001401893            4311 bp    mRNA    linear   ROD 26-APR-2024
DEFINITION  Rattus norvegicus syntaxin 16 (Stx16), transcript variant 1, mRNA.
ACCESSION   NM_001401893 XM_006235693
VERSION     NM_001401893.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4311)
  AUTHORS   Shitara,A., Shibui,T., Okayama,M., Arakawa,T., Mizoguchi,I.,
            Sakakura,Y. and Takuma,T.
  TITLE     VAMP4 is required to maintain the ribbon structure of the Golgi
            apparatus
  JOURNAL   Mol Cell Biochem 380 (1-2), 11-21 (2013)
   PUBMED   23677696
  REMARK    Erratum:[Mol Cell Biochem. 2013 Aug;380(1-2):301. Shakakura,
            Yasunori [corrected to Sakakura, Yasunori]]
REFERENCE   2  (bases 1 to 4311)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   3  (bases 1 to 4311)
  AUTHORS   Perez-Victoria,F.J. and Bonifacino,J.S.
  TITLE     Dual roles of the mammalian GARP complex in tethering and SNARE
            complex assembly at the trans-golgi network
  JOURNAL   Mol Cell Biol 29 (19), 5251-5263 (2009)
   PUBMED   19620288
REFERENCE   4  (bases 1 to 4311)
  AUTHORS   Best,D., Sahlender,D.A., Walther,N., Peden,A.A. and Adams,I.R.
  TITLE     Sdmg1 is a conserved transmembrane protein associated with germ
            cell sex determination and germline-soma interactions in mice
  JOURNAL   Development 135 (8), 1415-1425 (2008)
   PUBMED   18321981
REFERENCE   5  (bases 1 to 4311)
  AUTHORS   Ganley,I.G., Espinosa,E. and Pfeffer,S.R.
  TITLE     A syntaxin 10-SNARE complex distinguishes two distinct transport
            routes from endosomes to the trans-Golgi in human cells
  JOURNAL   J Cell Biol 180 (1), 159-172 (2008)
   PUBMED   18195106
REFERENCE   6  (bases 1 to 4311)
  AUTHORS   Wang,Y., Tai,G., Lu,L., Johannes,L., Hong,W. and Tang,B.L.
  TITLE     Trans-Golgi network syntaxin 10 functions distinctly from syntaxins
            6 and 16
  JOURNAL   Mol Membr Biol 22 (4), 313-325 (2005)
   PUBMED   16154903
  REMARK    Erratum:[Mol Membr Biol. 2005 Sep-Oct;22(5):453]
REFERENCE   7  (bases 1 to 4311)
  AUTHORS   Tai,G., Lu,L., Wang,T.L., Tang,B.L., Goud,B., Johannes,L. and
            Hong,W.
  TITLE     Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in
            transport from the early/recycling endosome to the trans-Golgi
            network
  JOURNAL   Mol Biol Cell 15 (9), 4011-4022 (2004)
   PUBMED   15215310
REFERENCE   8  (bases 1 to 4311)
  AUTHORS   Kreykenbohm,V., Wenzel,D., Antonin,W., Atlachkine,V. and von
            Mollard,G.F.
  TITLE     The SNAREs vti1a and vti1b have distinct localization and SNARE
            complex partners
  JOURNAL   Eur J Cell Biol 81 (5), 273-280 (2002)
   PUBMED   12067063
REFERENCE   9  (bases 1 to 4311)
  AUTHORS   Simonsen,A., Bremnes,B., Ronning,E., Aasland,R. and Stenmark,H.
  TITLE     Syntaxin-16, a putative Golgi t-SNARE
  JOURNAL   Eur J Cell Biol 75 (3), 223-231 (1998)
   PUBMED   9587053
REFERENCE   10 (bases 1 to 4311)
  AUTHORS   Tang,B.L., Low,D.Y., Lee,S.S., Tan,A.E. and Hong,W.
  TITLE     Molecular cloning and localization of human syntaxin 16, a member
            of the syntaxin family of SNARE proteins
  JOURNAL   Biochem Biophys Res Commun 242 (3), 673-679 (1998)
   PUBMED   9464276
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Mar 1, 2022 this sequence version replaced XM_006235693.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.382065.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-850               JAXUCZ010000003.1  183272071-183272920
            851-862             JAXUCZ010000003.1  183282619-183282630
            863-970             JAXUCZ010000003.1  183291659-183291766
            971-1111            JAXUCZ010000003.1  183292525-183292665
            1112-1277           JAXUCZ010000003.1  183293391-183293556
            1278-1369           JAXUCZ010000003.1  183294615-183294706
            1370-1513           JAXUCZ010000003.1  183295040-183295183
            1514-1594           JAXUCZ010000003.1  183296165-183296245
            1595-4311           JAXUCZ010000003.1  183298030-183300746
FEATURES             Location/Qualifiers
     source          1..4311
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..4311
                     /gene="Stx16"
                     /note="syntaxin 16"
                     /db_xref="GeneID:362283"
                     /db_xref="RGD:1309423"
     exon            1..850
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
     CDS             719..1699
                     /gene="Stx16"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="syntaxin-16 isoform 1"
                     /protein_id="NP_001388822.1"
                     /db_xref="GeneID:362283"
                     /db_xref="RGD:1309423"
                     /translation="MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHTTSSPLHSRSIAA
                     ELDELADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMRELASL
                     HDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARRTCSEQEERLLR
                     NVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTPVPLMDDGDDATLYGQG
                     FTDDQLVLVEQNTLVVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNV
                     EQSCVKTEDGLKQLHKAEQYQKKNRKMLVILILVAVIVVLIVVLIAVKSR"
     exon            851..862
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
     exon            863..970
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1111
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
     exon            1112..1277
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1369
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1513
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1594
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..4311
                     /gene="Stx16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttgggcag ggttgcagcc agatcccggg atggagggtt gccggtgaag aggattgaag
       61 aggagtgagg aggccgggga ggcaggccgt gaggtcctta ttgaaggcct acagcctgct
      121 ggcagtggag aaccaggcca cccaggaaag aaaggggtta ggtcgacctg agccataata
      181 gactcagtcg ccatatggga gctgtagacg ctttttgtag tcctgggctg gcctgtttga
      241 agcaggcctt ttgtgaggag agttaaccca aactcccaag ttagagccac atgccagaca
      301 cattagggtt agggcgccag cacctttggg gaggtcttag gaaatgagtg ggtaggggtc
      361 ttttccatcc cctagccgga ttggcgcgtt agacgcttgt agatccaagg ttggattggg
      421 gaggggtctc caggacgtta gatttctacg caaggattgg gggaattcaa gtgctttgag
      481 atctgagcca ggccttgggt agggggagtc agacaattgg aaagcctagg tggttatttg
      541 gggaggggtc tttgcgcttt ggtggagcgc aaaattgtgc cttaaaagcc taaggccttg
      601 tcaagagagg tttctatgca agagtggacc agctaggcca gaccaagaga aagaaagtga
      661 aaaatcagga ctataagggg gtgggggacc ctgagagggt ggtcacaaag ggtgagacat
      721 ggccaccagg cgtttaaccg acgctttctt gttgttgcgg aataattcca tccaaaaccg
      781 gcagctgtta gccgagcaag tgagtagtca caccacctcc agccctctgc attcacgtag
      841 cattgctgcg gagctggacg agctggctga tgaccgcatg gcgctggtgt caggcatcag
      901 cctagatcca gaagcagcaa ttggcgtgac aaagcggtcc cctccaaagt gggtggacgg
      961 agtagacgaa atacagtatg atgttggccg cattaaacag aagatgaggg agttagccag
     1021 ccttcatgat aagcatttga acagacccac gctggacgac agcagcgagg aggaacatgc
     1081 catcgagatc actacccagg aggtcacaca gctcttccat aggtgccagc gtgctgtgca
     1141 ggccctgccc agccgggcac gaaggacgtg ctcggagcag gaagagcggc tactgcggaa
     1201 tgtggtggcc tccctggcac aggccctgca ggagctgtct accagcttcc ggcatgcaca
     1261 gtctgactac ctgaaacgca tgaaaaaccg agaggaaaga tcgcagcatt tcttcgacac
     1321 cccggtacca ctaatggatg atggagatga tgctactctg tatggtcagg gtttcacgga
     1381 tgaccagctg gtgctggtgg agcagaacac actggtggtg gaggagaggg agcgagagat
     1441 ccgtcagatt gtacagtcca tttcagacct caacgaaatc ttcagggact tgggcgccat
     1501 gatcgtggag cagggcacag tccttgatcg aattgactat aatgttgaac aatcctgtgt
     1561 taagaccgaa gatggcttga agcaactgca caaggcagag cagtaccaga agaagaacag
     1621 gaagatgctt gtgatcttga tacttgtggc cgtcatcgtc gtcctcattg tggtcctcat
     1681 cgctgttaag tctcgctagt ggcactgagt tcttgagagc gctgctgcat ggagtagctg
     1741 ggcgctgggc tcggctggcg ccccaccact gaactgtcta cagagcacag cctcctggcc
     1801 acagtgggca gtgggtctcc cctgggctcc ctctaactgc agactggtgt gcaggcacag
     1861 ccgtgttttc cttcgctgtc cagagtcgaa gagactggcc tgcaacgagc tgtgctgtga
     1921 acggagtggc aggcacaggc ttcgctgacg ctgggtgacg tgtgcatgct ctctgttagc
     1981 actcctgtct gagcagcatg ttgagtaatt tttgggaaat ttttttcaac catctggttt
     2041 ttaagaagtt tggtaccaaa aatttatcag tgtagaggca atgcctcttt atcttcccag
     2101 ctgaaaacaa agcaagaagt ccttcaagga tttataatct gttcccatta acttaattta
     2161 gctttccatc actgttaacg atcagagtaa caaagtgtga aaaataagaa accatcattg
     2221 atgttaatta acacatttag acgggccagt taaaccagct ccatgccttt aaatcaactg
     2281 taaatagcat atttctcatt cagaattttg ccctgcattt tctactataa accaagaggg
     2341 gttactaagc caaacctcct gaatcagaaa cttggccatc tgaaccaacc tcacattaca
     2401 agaaagcttg acagtgttac gagctaggtt gaaccagtgt gtccccagcc acccttcctc
     2461 agtccattac ttatgttcta gctacgtaat gacctgtcca aacttgacgc catttaatga
     2521 actgtgattt tacacagagg ccattttaaa tgggtcaccc catttaggat tagtggatct
     2581 caaattatta accaaacatc actccatttc aaagtaaaat attcctccca tgatttgatt
     2641 tattgactcc tccgttgcca cttagctgtg cccagaaagt gggtatattc ccgaggacag
     2701 taaggacctc aactaccgaa accttatgta tatgtgtgtt ctgagtttct gtgcgtgcat
     2761 atgcgagagt gtgagtgagt atgtgtgagc gagcgtatca catgcatatc agatgccaac
     2821 gtggggctgt gtttacctgt aactacggtg cttgtgtgct ctgcagagcc agagccatac
     2881 ggaccagacg gacggagctc tgaagacgag ggtgtgcgta tctcacttgc tctgtttgca
     2941 tcaacactgc tgcaattttt gtgatctttg tgtaattgtt gatggctttt aaaaactgtc
     3001 tctgcctctc ttaaattatt taaacagcag cccctgttaa gtgtgttact ttgtgtttgg
     3061 actggcatat ggaacgcctt tctgggactc actgaagggc atctggaaac tccggctcag
     3121 atgcagacat ggagtcatat agagccgtca tgtgacagcc tctgcctgcc cgtgccatgg
     3181 gacgatgggg tccgaagctt tactgtgttc tctggcaatg ttaatagaga gggttgggaa
     3241 agaggaggcg gcacccaccc taccacttca gaactggggg aggagactcg gcagcctcct
     3301 ctcagcctct gaggttaggc tgctcctggg cggactggcc aaattagggc acttgctcca
     3361 agcaatctgt ggagatcatg ctgaggagtt gtgaaagcct tgaagaaagt gaccttttaa
     3421 gaaaaggagc actatttatt tataatttat ttccctgaat agattttttt ggagaggtgg
     3481 gggttgattt tcctctaact cacctggtta gaaattgtcc caaggacctg tggggagagg
     3541 gactgtcccc ttctgcctga aggcggtgtg ggctggtggg tgtcctgaag gcatggattc
     3601 tcggcctgta ccttgctccc gagctttatg cgcccactcg atggagtccc actgcccttt
     3661 tctgttgagc ctcttcttgt ggggaagatg aggagccttt gagaagtttt agtgtccatg
     3721 tcctggtacg gtaattacct cagggtaatt gcttttgaaa gaggactctc cgtacctgct
     3781 gacagtcaca cagacctgtc tctccctgtg cctgggaagc accttgggag gaagcccagc
     3841 ctctggacac cacctccctc tgctgccctg ctggctcttg tagagttggg gtggaaggag
     3901 agagggaaag agctgttggt ccttcggggc cccgatcttt cctaagacta gcttaaagtt
     3961 gctgtctgtc attttgtttg ttgggggtgg ggggacattg gggtgctggc tgggccactg
     4021 tgtgaagcaa tgtgtgtcta atttaacaga tgtaccactt tctctgctaa ttgagagagc
     4081 attatttatt tgttttgaca caagtgcttg cagcgtttca tcccagctaa tggcttctta
     4141 aaggtaataa aacccttcaa cctaattggt cagataagac ttttcccttg tatgcttaaa
     4201 taaagcaatt agtgaaatgc ttccatccaa aacgactttt tttttgtata aattaattta
     4261 ctgttactgg aaacttttgt acaataaagc aatctcacag attgaagagc a
//
