LOCUS       NM_001170539            2724 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus STT3 oligosaccharyltransferase complex catalytic
            subunit B (Stt3b), mRNA.
ACCESSION   NM_001170539 XM_002727142 XM_002729974 XR_005437 XR_009639
VERSION     NM_001170539.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2724)
  AUTHORS   Fu B, Wang L, Li S and Dorf ME.
  TITLE     ZMPSTE24 defends against influenza and other pathogenic viruses
  JOURNAL   J Exp Med 214 (4), 919-929 (2017)
   PUBMED   28246125
REFERENCE   2  (bases 1 to 2724)
  AUTHORS   Roboti P and High S.
  TITLE     The oligosaccharyltransferase subunits OST48, DAD1 and KCP2
            function as ubiquitous and selective modulators of mammalian
            N-glycosylation
  JOURNAL   J Cell Sci 125 (Pt 14), 3474-3484 (2012)
   PUBMED   22467853
REFERENCE   3  (bases 1 to 2724)
  AUTHORS   Sato T, Sako Y, Sho M, Momohara M, Suico MA, Shuto T, Nishitoh H,
            Okiyoneda T, Kokame K, Kaneko M, Taura M, Miyata M, Chosa K, Koga
            T, Morino-Koga S, Wada I and Kai H.
  TITLE     STT3B-dependent posttranslational N-glycosylation as a surveillance
            system for secretory protein
  JOURNAL   Mol Cell 47 (1), 99-110 (2012)
   PUBMED   22607976
REFERENCE   4  (bases 1 to 2724)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 2724)
  AUTHORS   Ruiz-Canada C, Kelleher DJ and Gilmore R.
  TITLE     Cotranslational and posttranslational N-glycosylation of
            polypeptides by distinct mammalian OST isoforms
  JOURNAL   Cell 136 (2), 272-283 (2009)
   PUBMED   19167329
REFERENCE   6  (bases 1 to 2724)
  AUTHORS   Kelleher DJ, Karaoglu D, Mandon EC and Gilmore R.
  TITLE     Oligosaccharyltransferase isoforms that contain different catalytic
            STT3 subunits have distinct enzymatic properties
  JOURNAL   Mol Cell 12 (1), 101-111 (2003)
   PUBMED   12887896
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166740.1.
            
            On or before May 22, 2010 this sequence version replaced
            XM_002727142.1, XM_002729974.2, XR_005437.1, XR_009639.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166740.1, FQ210494.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..2724
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..2724
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /note="STT3 oligosaccharyltransferase complex catalytic
                     subunit B"
                     /db_xref="GeneID:363160"
                     /db_xref="RGD:1311563"
     exon            1..372
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..2539
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /note="source of immunodominant MHC-associated peptides;
                     STT3B, catalytic subunit of the oligosaccharyltransferase
                     complex; STT3B, subunit of the oligosaccharyltransferase
                     complex (catalytic)"
                     /codon_start=1
                     /product="dolichyl-diphosphooligosaccharide--protein
                     glycosyltransferase subunit STT3B"
                     /protein_id="NP_001164010.1"
                     /db_xref="GeneID:363160"
                     /db_xref="RGD:1311563"
                     /translation="MAEPSAPESKHKSSLNSSPWSGLMALGNSRHGHHGPGAQSASRA
                     AAAPKPGPPAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDP
                     WFNYRSTHHLASHGFYEFLNWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILNTLNI
                     TVHIRDVCVFLAPTFSGLTSISTFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSF
                     DNEGIAIFALQFTYYLWVKSVKTGSVFWTMCCCLSYFYMVSAWGGYVFIINLIPLHVF
                     VLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPIRTSEHMAAAGVFALLQAYAF
                     LQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYSLWDTGYAK
                     IHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVY
                     FAGVMVRLMLTLTPVVCMLSAIAFSSVFEHYLGDDMKRENPPVEDSSDEDDRRSPGNL
                     YDKAGKVRKHVTEQEKPEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVV
                     LASYNHDGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTW
                     NNSHIALVGKAMSSNETAAYKIMRSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEG
                     EHPKDIREGDYFTQQGEFRVDRAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTR
                     NAEIGNKDIKFKHLEEAFTSEHWLVRIYKVKAPDNRETLGHKPRVTNIFPKQKYLSKK
                     TTKRKRGYVKNKLVFKKGKKMSKKTV"
     exon            373..481
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            482..769
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            770..835
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            836..935
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1034
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1181
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1230
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1385
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1597
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1785
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            1786..1957
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2131
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2245
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            2246..2458
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
     exon            2459..2706
                     /gene="Stt3b"
                     /gene_synonym="RGD1311563"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccctcgctc caggcggcgg cggtggccgc ggaggactag cgagacccgc cgccggggca
       61 caacatggcg gagccctcgg ccccggagag caagcacaag tcgtctctca actcgtcccc
      121 gtggagcggc ctcatggctc tggggaacag ccgccacggg caccacgggc ccggagccca
      181 gagcgcttcc agggcggcgg cggcgccgaa gccggggccc cccgcggggc tgtccggggg
      241 cttgtcgcag ccggccgggt ggcagtcttt gctctccttc accatcctct tcctggcctg
      301 gctggccggc ttcagctcgc gcctcttcgc cgtcatccgc ttcgagagca tcatccacga
      361 gttcgacccg tggtttaact atagatcaac tcatcatctt gcatctcatg ggttctatga
      421 gttcttaaat tggtttgatg aaagagcatg gtacccacta ggaagaatcg tgggtggcac
      481 cgtttaccca ggattgatga taacagctgg ccttattcat tggattttaa atacattgaa
      541 cataacagtt cacatcagag atgtatgtgt gttccttgca ccaactttta gcggccttac
      601 atctatatct acgttcctgc taactagaga actttggaac cagggagcag ggctcttagc
      661 tgcctgcttc attgctattg tacccgggta catatctcgg tcggtagcgg gatcctttga
      721 taacgaaggc attgcgattt tcgcacttca gttcacttac tacttatggg tgaagtctgt
      781 gaaaaccggg tctgtgtttt ggacaatgtg ctgctgcttg tcgtatttct acatggtctc
      841 tgcgtgggga ggttatgtgt tcatcatcaa cctcatccct ctccatgtgt ttgtgctgct
      901 cctgatgcag aggtacagca agagagtcta catagcatat agcactttct acattgtggg
      961 tttaatatta tccatgcaga taccttttgt gggattccag ccaatcagga caagcgagca
     1021 catggcagct gcaggtgtct ttgcgctgct gcaggcttat gcgtttctgc agtatctgag
     1081 agaccggttg acaaagcagg agttccagac ccttttcttt ttgggtgtct cactagctgc
     1141 aggcgctgtg ttccttagtg tcatctatct gacatacaca ggttacattg caccatggag
     1201 tggcaggttt tattcattat gggatactgg gtatgcaaaa atacacattc caattattgc
     1261 atcagtgtct gaacatcagc ctacgacatg ggtgtctttc ttctttgatc tacatattct
     1321 tgtgtgtacc ttcccagcag gcctatggtt ctgcatcaaa aatatcaacg atgaaagagt
     1381 atttgttgct ctgtatgcga tcagtgctgt ctactttgct ggagtaatgg tacggctgat
     1441 gctgactctg accccagtcg tctgcatgct gtctgcaatt gccttctcca gtgtttttga
     1501 gcactatttg ggggatgaca tgaaaaggga aaacccacct gtggaggaca gcagtgacga
     1561 ggatgacaga agaagcccag gaaacttgta tgacaaggca gggaaagtga gaaagcatgt
     1621 gacggagcag gagaagccgg aggagggctt gggccccaac atcaagagca tcgtgaccat
     1681 gctcatgctc atgctcctca tgatgttcgc tgtgcactgc acctgggtca ccagcaatgc
     1741 ctactccagc cccagtgtgg tcctcgcctc ctacaatcat gatggaacca gaaatatctt
     1801 agatgatttt agagaagcat acttttggtt gagacaaaac acggatgaac acgccagggt
     1861 catgtcctgg tgggactatg gctatcagat tgctgggatg gccaacagga ctactctggt
     1921 agacaataac acctggaaca acagccacat tgcactggta ggaaaagcta tgtcttctaa
     1981 tgaaacagcc gcctataaaa tcatgaggtc tcttgacgtt gattatgtgt tggtcatttt
     2041 tggaggagtt attggctatt ctggtgatga tatcaacaag ttcctctgga tggtcaggat
     2101 agctgaaggg gagcacccaa aagacattcg ggaaggcgac tacttcaccc agcagggaga
     2161 gttccgagtg gacagagccg ggtctcctac tctgttaaat tgccttatgt ataaaatgtc
     2221 atactacaga tttggagaaa tgcagctaga ttttcgcaca ccccccggtt ttgaccgaac
     2281 acgtaatgct gagatcggaa ataaggacat taaattcaag catttggagg aagcctttac
     2341 atcagagcac tggcttgtca ggatatataa agtgaaagca cccgacaaca gggagacatt
     2401 aggtcacaag cctcgagtca ccaacatctt ccccaaacag aagtatttgt caaagaagac
     2461 tactaaaagg aagcgtggct acgttaaaaa taagctagtt tttaagaaag gcaagaaaat
     2521 gtctaagaag actgtttaaa tacactgtct ggcctgactt gcagcagtcc ttgtgagaac
     2581 ccgtctttgc cttccgctcg tgtcctgctt cacagcacca agggtacaga acatcgctgg
     2641 gccaagtcaa tgtacaaaat tttctggcaa tgcctcattt aaaattaaat tggtttattg
     2701 agaacaaaaa aaaaaaaaaa aaaa
//
