LOCUS       NM_001029897            4139 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Rattus norvegicus striatin 3 (Strn3), mRNA.
ACCESSION   NM_001029897 XM_343059
VERSION     NM_001029897.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4139)
  AUTHORS   Bisoyi,P., Ratna,D., Kumar,G., Mallick,B.N. and Goswami,S.K.
  TITLE     In the Rat Midbrain, SG2NA and DJ-1 have Common Interactome,
            Including Mitochondrial Electron Transporters that are Comodulated
            Under Oxidative Stress
  JOURNAL   Cell Mol Neurobiol 43 (7), 3061-3080 (2023)
   PUBMED   37165139
  REMARK    GeneRIF: In the Rat Midbrain, SG2NA and DJ-1 have Common
            Interactome, Including Mitochondrial Electron Transporters that are
            Comodulated Under Oxidative Stress.
            Review article
            Erratum:[Cell Mol Neurobiol. 2023 Oct;43(7):3081. doi:
            10.1007/s10571-023-01369-x.. PMID: 37278863]
REFERENCE   2  (bases 1 to 4139)
  AUTHORS   Lant,B., Yu,B., Goudreault,M., Holmyard,D., Knight,J.D., Xu,P.,
            Zhao,L., Chin,K., Wallace,E., Zhen,M., Gingras,A.C. and Derry,W.B.
  TITLE     CCM-3/STRIPAK promotes seamless tube extension through endocytic
            recycling
  JOURNAL   Nat Commun 6, 6449 (2015)
   PUBMED   25743393
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4139)
  AUTHORS   Goudreault,M., D'Ambrosio,L.M., Kean,M.J., Mullin,M.J.,
            Larsen,B.G., Sanchez,A., Chaudhry,S., Chen,G.I., Sicheri,F.,
            Nesvizhskii,A.I., Aebersold,R., Raught,B. and Gingras,A.C.
  TITLE     A PP2A phosphatase high density interaction network identifies a
            novel striatin-interacting phosphatase and kinase complex linked to
            the cerebral cavernous malformation 3 (CCM3) protein
  JOURNAL   Mol Cell Proteomics 8 (1), 157-171 (2009)
   PUBMED   18782753
REFERENCE   4  (bases 1 to 4139)
  AUTHORS   Breitman,M., Zilberberg,A., Caspi,M. and Rosin-Arbesfeld,R.
  TITLE     The armadillo repeat domain of the APC tumor suppressor protein
            interacts with Striatin family members
  JOURNAL   Biochim Biophys Acta 1783 (10), 1792-1802 (2008)
   PUBMED   18502210
REFERENCE   5  (bases 1 to 4139)
  AUTHORS   Tan,B., Long,X., Nakshatri,H., Nephew,K.P. and Bigsby,R.M.
  TITLE     Striatin-3 gamma inhibits estrogen receptor activity by recruiting
            a protein phosphatase
  JOURNAL   J Mol Endocrinol 40 (5), 199-210 (2008)
   PUBMED   18434427
  REMARK    GeneRIF: A rat STRN3 gamma-protein phosphatase 2A complex is
            recruited to agonist-activated estrogen receptor alpha, thereby
            leading to its dephosphorylation and inhibiting transcription.
REFERENCE   6  (bases 1 to 4139)
  AUTHORS   Gaillard,S., Bailly,Y., Benoist,M., Rakitina,T., Kessler,J.P.,
            Fronzaroli-Molinieres,L., Dargent,B. and Castets,F.
  TITLE     Targeting of proteins of the striatin family to dendritic spines:
            role of the coiled-coil domain
  JOURNAL   Traffic 7 (1), 74-84 (2006)
   PUBMED   16445688
REFERENCE   7  (bases 1 to 4139)
  AUTHORS   Blondeau,C., Gaillard,S., Ternaux,J.P., Monneron,A. and Baude,A.
  TITLE     Expression and distribution of phocein and members of the striatin
            family in neurones of rat peripheral ganglia
  JOURNAL   Histochem Cell Biol 119 (2), 131-138 (2003)
   PUBMED   12610732
REFERENCE   8  (bases 1 to 4139)
  AUTHORS   Zhu,W., Chan,E.K., Li,J., Hemmerich,P. and Tan,E.M.
  TITLE     Transcription activating property of autoantigen SG2NA and
            modulating effect of WD-40 repeats
  JOURNAL   Exp Cell Res 269 (2), 312-321 (2001)
   PUBMED   11570823
REFERENCE   9  (bases 1 to 4139)
  AUTHORS   Baillat,G., Moqrich,A., Castets,F., Baude,A., Bailly,Y.,
            Benmerah,A. and Monneron,A.
  TITLE     Molecular cloning and characterization of phocein, a protein found
            from the Golgi complex to dendritic spines
  JOURNAL   Mol Biol Cell 12 (3), 663-673 (2001)
   PUBMED   11251078
REFERENCE   10 (bases 1 to 4139)
  AUTHORS   Castets,F., Rakitina,T., Gaillard,S., Moqrich,A., Mattei,M.G. and
            Monneron,A.
  TITLE     Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat
            proteins principally expressed in the brain
  JOURNAL   J Biol Chem 275 (26), 19970-19977 (2000)
   PUBMED   10748158
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Oct 7, 2014 this sequence version replaced NM_001029897.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.35478.1,
                                           SRR22582424.1325165.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-495               JAXUCZ010000006.1  74868979-74869473   c
            496-599             JAXUCZ010000006.1  74836897-74837000   c
            600-673             JAXUCZ010000006.1  74836433-74836506   c
            674-752             JAXUCZ010000006.1  74830351-74830429   c
            753-926             JAXUCZ010000006.1  74828557-74828730   c
            927-1053            JAXUCZ010000006.1  74826584-74826710   c
            1054-1195           JAXUCZ010000006.1  74824915-74825056   c
            1196-1306           JAXUCZ010000006.1  74819397-74819507   c
            1307-1447           JAXUCZ010000006.1  74810290-74810430   c
            1448-1581           JAXUCZ010000006.1  74806093-74806226   c
            1582-1757           JAXUCZ010000006.1  74804479-74804654   c
            1758-1805           JAXUCZ010000006.1  74804277-74804324   c
            1806-1927           JAXUCZ010000006.1  74803875-74803996   c
            1928-2095           JAXUCZ010000006.1  74801820-74801987   c
            2096-2236           JAXUCZ010000006.1  74800460-74800600   c
            2237-2344           JAXUCZ010000006.1  74798821-74798928   c
            2345-2431           JAXUCZ010000006.1  74784944-74785030   c
            2432-4139           JAXUCZ010000006.1  74783156-74784863   c
FEATURES             Location/Qualifiers
     source          1..4139
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q23"
     gene            1..4139
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /note="striatin 3"
                     /db_xref="GeneID:114520"
                     /db_xref="RGD:621827"
     exon            1..495
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     CDS             217..2601
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /note="striatin-3-gamma; s/G2 antigen; cell cycle
                     autoantigen SG2NA; nuclear autoantigen; striatin,
                     calmodulin binding protein 3"
                     /codon_start=1
                     /product="striatin-3"
                     /protein_id="NP_001025068.1"
                     /db_xref="GeneID:114520"
                     /db_xref="RGD:621827"
                     /translation="MDELAGGGGGQGMAVPPRPQQGPGGNLSLPPGANGAPGGGGPPA
                     AETAGPPAGPELSRPQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGE
                     RKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDAEA
                     PPAQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSIEAKNL
                     EQILNGGESPKQKGQEIKRPSGDVLETFNFLENADDSDEEENDMIEGIPEGKDKLRIH
                     KHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPT
                     AEVWDVDQGLMSKLKEQYKKERKGKRGAKRVNRTNLCDMITDLGDDELPHIPSGIINQ
                     SRSASTRMTDHEGSRAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDA
                     DYSYDLPANKDALRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQK
                     TVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDP
                     YDTYESHVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCICTYNG
                     DKEHGIPTSVDFIGCDPAHMVTSFNTGSAIIYDLETSQSLVMLSSQVDSGLQSSNHIN
                     RVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSH
                     DCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV"
     exon            496..599
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            600..673
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            674..752
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            753..926
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1053
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1195
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1306
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..1447
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1581
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1757
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            1758..1805
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1927
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2095
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2236
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            2237..2344
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2431
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
     exon            2432..4139
                     /gene="Strn3"
                     /gene_synonym="Gs2na; Sg2na"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaagtgagtg agtgagacgg gcagatggag gagggactgt aatggcggcg gccggcagct
       61 ccctgctctg atccgcggca agcacaccgc agcgaccccc tccccggccc tctcccggcc
      121 ggacccccgc cctgccgtca gcgcggggcc accgtcccgg ccctctccgc agctgtcggt
      181 gtctcgctct gcgccccaac cggggcccca cacacaatgg acgagctggc cggaggcggc
      241 ggcggccagg ggatggcggt ccctccccga ccgcagcagg gacccggggg gaacctgagc
      301 cttccgccgg gagcgaacgg agcgccgggc ggtgggggtc ctccggccgc cgagacggcg
      361 gggcccccgg caggccccga gctgtcccgg ccgcaacagt acactattcc gggaatactg
      421 cactacatcc agcacgagtg ggctcggttc gagatggagc gggcgcactg ggaggtggaa
      481 cgggccgaac tgcaggcacg aattgcattt ttacaaggtg aaaggaaagg tcaagaaaat
      541 ttgaagaagg atttagtgag aagaataaag atgttagagt atgcattaaa acaagaaagg
      601 gcaaagtatc acaaattaaa atatggcaca gaactgaacc aaggtgattt gaaaatgccc
      661 acctttgaat cagaggaaac caaagatgcg gaggctcctc cagcccaaaa cagccagctg
      721 acgtggaagc aaggcagaca gctgttaaga cagtatcttc aggaagtagg atatacagat
      781 acaatattag atgtacgatc tcagcgggta aggtcattac ttggactgtc taattcagag
      841 ccaaatggat ccatagaagc aaagaattta gaacagatcc tgaatggtgg tgaatctcct
      901 aaacaaaaag gacaagaaat caaaaggccc tctggtgatg ttcttgagac attcaatttc
      961 ttagaaaatg ccgatgacag tgacgaagaa gaaaatgaca tgattgaggg catcccggaa
     1021 ggaaaagaca aacttcggat ccataagcac aaaataggta atgaaggttt agctgctgac
     1081 ttaactgatg atcctgatac tgaggaagca ctgaaagaat tcgacttttt agtgactgca
     1141 gaagatggtg aaggggctgg tgaagcacgg agttcagggg atggtacaga atgggataag
     1201 gatgacctct cccccactgc tgaggtttgg gatgtagacc aggggctaat gagtaagctg
     1261 aaggagcagt acaagaagga gcggaagggg aagagagggg caaagagggt caacaggaca
     1321 aacctctgcg acatgataac tgatctggga gatgatgagc tgccccacat cccttcagga
     1381 atcattaatc agtctaggtc agcctctact agaatgactg atcatgaagg ttcaagagca
     1441 gaggaagctg aaccaataac gtttccatct ggaggaggca agtcatttat tatgggttct
     1501 gatgatgttt tgttaagtgt actgggcctt ggagaccttg cagacttgac ggtaacaaat
     1561 gatgcagact atagttatga tttgcctgcc aataaagatg ccttgcgaaa gacttggaac
     1621 cccaagtata cactacgcag tcactttgat ggcgtgagag cattagcttt ccaccctgta
     1681 gaacctgtgc ttgttactgc ctctgaggac cacaccctga aactttggaa cttgcaaaag
     1741 acagttcctg ccaaaaagag tgcctcttta gatgtagagc ctatctacac atttagggcc
     1801 cacattggcc ctgtcctatc attagctatt agttctaatg gagaacagtg ttttagtggt
     1861 ggtattgacg caaccattca gtggtggaat atgcctagtc ctaatgtgga tccctatgat
     1921 acatatgagt cccatgttct agctggcact ttagttgctc atacagatgc agtctggggt
     1981 cttgcctaca gtggcataaa aaatcaatta ctctcttgtt cagcagatgg cactattagg
     2041 ttatggaatc cacaagaaaa attgccatgt atttgcactt acaacggaga caaggaacat
     2101 ggaataccta catcagttga ctttataggc tgtgatccag ctcatatggt tacctctttc
     2161 aacactggta gtgcgataat ttatgattta gaaacatcac agtcattagt gatgctttcc
     2221 tcacaggtgg attctggttt acaatctagt aatcacatta acagagtagt aagtcaccct
     2281 acacttcctg ttacaataac tgcccatgaa gatagacaca tcaagttttt tgacaataaa
     2341 acgggtaaaa tgatccattc tatggtagct cacttggatg ctgttacaag tttagcagta
     2401 gatcccaatg gaatctattt gatgtctgga agccatgact gctctattag attatggaat
     2461 ttggacagta agacatgtgt acaagaaata acagcccata ggaagaaatt ggatgagtca
     2521 atttatgatg ttgctttcca tccgtcaaag gcatatatcg ccagtgcagg ggctgatgct
     2581 cttgccaaag tatttgtgtg aaccaacata gactcgtgtt gtgggaagaa aagatttact
     2641 tggtcagaaa gggggtctgc atcactgcca tcacgaaagc tactgatagg acactacatg
     2701 tgatctgcct ggtgaaagct gttggaggca ggcagaaatt gggaatcaca tcctaatgtc
     2761 aggcttatta gtttaactgt aattaactgt attttgtggg acagaaagaa aaaggactcc
     2821 agtatctgtg ccctgtactg gatatgaact gagcggtttt tgttttttgt tgtttttttg
     2881 ttgtttgttt gtttgtttgt tttttttaag tgtttaagcc aatgtggagt ctgatcttag
     2941 gggaaaagga ctttttgttg gactctgtgt gctgccttag ggttaggaat gtggtgctct
     3001 tgtggggaag caagctccaa gagtagcttt tttcatctct tagtgatctt acatttatca
     3061 gttgaatgcc acagattccc ttttaaactt attttgcttt aaaaaaaaga aaaaagaaaa
     3121 agaaaaaaga gagaaaagaa aatttaactt aaaatatttt agcattagtt gcacaaaatg
     3181 tttggataaa attctagttt ttataagtct ttttatatat ttagcctgtc acaacagtgc
     3241 tcaagatcat attgatgttt ttctgcatta tacaacccta aaacacagag atctcactaa
     3301 cctgccacct ataaccactt tctttcctcc ttttgcctaa tacagctcag ctaagtcctt
     3361 cataaagatg ataatctcct tcgtctacat gtcttcataa accaaggact attagtgaat
     3421 taaaacaaag gtgtggagtt tagtactcca gatgaactct ttaaaaacta atcctgacat
     3481 cctatcacta tgtgatattt tgtacatctt actgtattta caagtttatt tatcaaggat
     3541 tatccatctt gctaatggcc tattatttat tttacttttt gttggtcttt atatcctttt
     3601 attaatgctc taaaggaacc tgtatatcta ttttggaatc tattttgttc gtgttgaaca
     3661 gtctaaaata gactaaaaat ggaatatttt atagttaagt tacaaaccaa ggtgtttctc
     3721 cccaagatac tatcttgatt taccatgatt ccaaaacaaa atgatctagt taaaaaaaaa
     3781 aattggagga tattttatta ccattacaaa taagatattt aaaaaacttg aatcaggata
     3841 cagaagtctg ctggatttgg actagtcttc cctgttttat ttttttagat gtgcttactt
     3901 ttatggtgta actgaagatt ttctttgtgt aatgcatgat taagacaata aagtattttt
     3961 tctagtcttc caaaagcctt ttctgatcag tttgcgagtt ttgatgagtt ttgtaaggtt
     4021 tttgttttac agactatgaa tcagcaaatt tttaagattg taccacagag caaacacaca
     4081 gctgttgaaa aataatgtat ataaaatgca tataataaat attaaattgt gtacctgta
//
