LOCUS       NM_001031646            1213 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus stomatin like 2 (Stoml2), mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001031646 XM_216439
VERSION     NM_001031646.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1213)
  AUTHORS   Forster,F., Paster,W., Supper,V., Schatzlmaier,P., Sunzenauer,S.,
            Ostler,N., Saliba,A., Eckerstorfer,P., Britzen-Laurent,N.,
            Schutz,G., Schmid,J.A., Zlabinger,G.J., Naschberger,E., Sturzl,M.
            and Stockinger,H.
  TITLE     Guanylate binding protein 1-mediated interaction of T cell antigen
            receptor signaling with the cytoskeleton
  JOURNAL   J Immunol 192 (2), 771-781 (2014)
   PUBMED   24337748
REFERENCE   2  (bases 1 to 1213)
  AUTHORS   Christie,D.A., Mitsopoulos,P., Blagih,J., Dunn,S.D., St-Pierre,J.,
            Jones,R.G., Hatch,G.M. and Madrenas,J.
  TITLE     Stomatin-like protein 2 deficiency in T cells is associated with
            altered mitochondrial respiration and defective CD4+ T cell
            responses
  JOURNAL   J Immunol 189 (9), 4349-4360 (2012)
   PUBMED   23028053
REFERENCE   3  (bases 1 to 1213)
  AUTHORS   Christie,D.A., Kirchhof,M.G., Vardhana,S., Dustin,M.L. and
            Madrenas,J.
  TITLE     Mitochondrial and plasma membrane pools of stomatin-like protein 2
            coalesce at the immunological synapse during T cell activation
  JOURNAL   PLoS One 7 (5), e37144 (2012)
   PUBMED   22623988
REFERENCE   4  (bases 1 to 1213)
  AUTHORS   Palmer,C.S., Osellame,L.D., Stojanovski,D. and Ryan,M.T.
  TITLE     The regulation of mitochondrial morphology: intricate mechanisms
            and dynamic machinery
  JOURNAL   Cell Signal 23 (10), 1534-1545 (2011)
   PUBMED   21683788
  REMARK    Review article
REFERENCE   5  (bases 1 to 1213)
  AUTHORS   Christie,D.A., Lemke,C.D., Elias,I.M., Chau,L.A., Kirchhof,M.G.,
            Li,B., Ball,E.H., Dunn,S.D., Hatch,G.M. and Madrenas,J.
  TITLE     Stomatin-like protein 2 binds cardiolipin and regulates
            mitochondrial biogenesis and function
  JOURNAL   Mol Cell Biol 31 (18), 3845-3856 (2011)
   PUBMED   21746876
REFERENCE   6  (bases 1 to 1213)
  AUTHORS   Fang,L., Wang,X., Yamoah,K., Chen,P.L., Pan,Z.Q. and Huang,L.
  TITLE     Characterization of the human COP9 signalosome complex using
            affinity purification and mass spectrometry
  JOURNAL   J Proteome Res 7 (11), 4914-4925 (2008)
   PUBMED   18850735
REFERENCE   7  (bases 1 to 1213)
  AUTHORS   Kirchhof,M.G., Chau,L.A., Lemke,C.D., Vardhana,S., Darlington,P.J.,
            Marquez,M.E., Taylor,R., Rizkalla,K., Blanca,I., Dustin,M.L. and
            Madrenas,J.
  TITLE     Modulation of T cell activation by stomatin-like protein 2
  JOURNAL   J Immunol 181 (3), 1927-1936 (2008)
   PUBMED   18641330
REFERENCE   8  (bases 1 to 1213)
  AUTHORS   Hajek,P., Chomyn,A. and Attardi,G.
  TITLE     Identification of a novel mitochondrial complex containing
            mitofusin 2 and stomatin-like protein 2
  JOURNAL   J Biol Chem 282 (8), 5670-5681 (2007)
   PUBMED   17121834
REFERENCE   9  (bases 1 to 1213)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   10 (bases 1 to 1213)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099164.1.
            
            On Aug 12, 2005 this sequence version replaced XM_216439.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099164.1, FQ213146.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN11044071, SAMN12840132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1213
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..1213
                     /gene="Stoml2"
                     /note="stomatin like 2"
                     /db_xref="GeneID:298203"
                     /db_xref="RGD:1308285"
     exon            1..46
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     CDS             2..1063
                     /gene="Stoml2"
                     /note="SLP-2; stomatin (Epb7.2)-like 2"
                     /codon_start=1
                     /product="stomatin-like protein 2, mitochondrial"
                     /protein_id="NP_001026816.1"
                     /db_xref="GeneID:298203"
                     /db_xref="RGD:1308285"
                     /translation="MLARAARGTGALLLRGSVQASGRIPRRASSGLPRNTVILFVPQQ
                     EAWVVERMGRFHRILEPGLNVLIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQID
                     GVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDA
                     INQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVA
                     EGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQHNGDAAASL
                     TVAEQYVSAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTKAPVPGAQNSSEAR
                     RDVQTTDTSIEELGRVKLS"
     exon            47..184
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     exon            185..284
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     exon            285..343
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     exon            344..445
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     exon            446..580
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     exon            581..725
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     exon            726..805
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     exon            806..934
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
     exon            935..1190
                     /gene="Stoml2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatgctggcg cgcgcggcgc ggggcactgg agcccttttg ctgaggggct ccgtgcaggc
       61 ttctggccgc attccgcgcc gcgcctcctc tggactgccc cgaaacaccg tgatactgtt
      121 tgtgcctcag caggaggcct gggtggtgga gcgaatgggc agattccacc ggatcctgga
      181 acctggcttg aacgtcctca tccccgtgtt agaccgaatc cggtatgtgc agagtctcaa
      241 ggaaattgtt atcaacgtgc ctgagcaatc agctgtaact cttgataatg taactctaca
      301 aatagatgga gtcctttatc tgcgcattat ggatccttac aaggcaagtt atggtgtgga
      361 agaccccgag tatgcggtca cccagttagc tcagacgact atgagatcag agcttggcaa
      421 actctctctg gacaaagttt ttcgggaacg tgagtccctg aacgccaaca ttgtggacgc
      481 catcaaccag gctgctgact gctggggtat ccgatgcttg cgttatgaga tcaaggatat
      541 ccacgtgcca ccccgagtca aagagtccat gcagatgcag gtagaggcag agcggcggaa
      601 gcgggccaca gttctagagt ctgaagggac acgagagtca gctatcaatg tggcagaggg
      661 gaagaaacag gcccagattc tggcctcgga agcagaaaag gctgaacaga taaatcaggc
      721 agcaggagaa gccagtgcag ttctggccaa ggccaaggct aaagctgaag ccattcgaat
      781 tctggctggg gctctgactc aacacaatgg agacgcagca gcttcactga ctgtggctga
      841 gcagtacgtc agcgccttct ccaaactggc caaggattcc aacaccgtcc tcctgccctc
      901 caatcccagc gatgtgacaa gtatggtggc tcaggccatg ggtgtctatg gcgctctcac
      961 caaagcccca gtgcccggag cgcagaactc cagcgaggcc agaagagatg tccagactac
     1021 agacacgagt attgaagaac tgggcagagt caagctcagt tagtagagac ggctcggcca
     1081 gagttagggc cgggaactct cagattctgg ctccagcctc ccggccaaag tttagttttt
     1141 atttttttat ttgaacttaa taatcatgta ataaactcac cagtggcaaa aaaaaaaaaa
     1201 aaaaaaaaaa aaa
//
