LOCUS       NM_001011965            1792 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus stomatin (Stom), mRNA.
ACCESSION   NM_001011965 XM_216045
VERSION     NM_001011965.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1792)
  AUTHORS   Klipp RC, Cullinan MM and Bankston JR.
  TITLE     Insights into the molecular mechanisms underlying the inhibition of
            acid-sensing ion channel 3 gating by stomatin
  JOURNAL   J Gen Physiol 152 (3) (2020)
   PUBMED   32012213
  REMARK    GeneRIF: Insights into the molecular mechanisms underlying the
            inhibition of acid-sensing ion channel 3 gating by stomatin.
REFERENCE   2  (bases 1 to 1792)
  AUTHORS   Kim JH, Rhee JK, Ahn DG, Kim KP and Oh JW.
  TITLE     Interaction of stomatin with hepatitis C virus RNA polymerase
            stabilizes the viral RNA replicase complexes on detergent-resistant
            membranes
  JOURNAL   J Microbiol Biotechnol 24 (12), 1744-1754 (2014)
   PUBMED   25262680
REFERENCE   3  (bases 1 to 1792)
  AUTHORS   Brand J, Smith ES, Schwefel D, Lapatsina L, Poole K, Omerbasic D,
            Kozlenkov A, Behlke J, Lewin GR and Daumke O.
  TITLE     A stomatin dimer modulates the activity of acid-sensing ion
            channels
  JOURNAL   EMBO J 31 (17), 3635-3646 (2012)
   PUBMED   22850675
REFERENCE   4  (bases 1 to 1792)
  AUTHORS   Bastos-Amador P, Royo F, Gonzalez E, Conde-Vancells J, Palomo-Diez
            L, Borras FE and Falcon-Perez JM.
  TITLE     Proteomic analysis of microvesicles from plasma of healthy donors
            reveals high individual variability
  JOURNAL   J Proteomics 75 (12), 3574-3584 (2012)
   PUBMED   22516433
REFERENCE   5  (bases 1 to 1792)
  AUTHORS   Stamer WD, Hoffman EA, Luther JM, Hachey DL and Schey KL.
  TITLE     Protein profile of exosomes from trabecular meshwork cells
  JOURNAL   J Proteomics 74 (6), 796-804 (2011)
   PUBMED   21362503
REFERENCE   6  (bases 1 to 1792)
  AUTHORS   Palmer DJ, Kelly VC, Smit AM, Kuy S, Knight CG and Cooper GJ.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
REFERENCE   7  (bases 1 to 1792)
  AUTHORS   Mairhofer M, Steiner M, Mosgoeller W, Prohaska R and Salzer U.
  TITLE     Stomatin is a major lipid-raft component of platelet alpha granules
  JOURNAL   Blood 100 (3), 897-904 (2002)
   PUBMED   12130500
REFERENCE   8  (bases 1 to 1792)
  AUTHORS   Zhang JZ, Hayashi H, Ebina Y, Prohaska R and Ismail-Beigi F.
  TITLE     Association of stomatin (band 7.2b) with Glut1 glucose transporter
  JOURNAL   Arch Biochem Biophys 372 (1), 173-178 (1999)
   PUBMED   10562431
REFERENCE   9  (bases 1 to 1792)
  AUTHORS   Snyers L, Umlauf E and Prohaska R.
  TITLE     Oligomeric nature of the integral membrane protein stomatin
  JOURNAL   J Biol Chem 273 (27), 17221-17226 (1998)
   PUBMED   9642292
REFERENCE   10 (bases 1 to 1792)
  AUTHORS   Stewart GW, Hepworth-Jones BE, Keen JN, Dash BC, Argent AC and
            Casimir CM.
  TITLE     Isolation of cDNA coding for an ubiquitous membrane protein
            deficient in high Na+, low K+ stomatocytic erythrocytes
  JOURNAL   Blood 79 (6), 1593-1601 (1992)
   PUBMED   1547348
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083895.1.
            
            On Feb 11, 2005 this sequence version replaced XM_216045.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083895.1, FQ182952.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1792
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p11"
     gene            1..1792
                     /gene="Stom"
                     /note="stomatin"
                     /db_xref="GeneID:296655"
                     /db_xref="RGD:1305109"
     exon            1..96
                     /gene="Stom"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..890
                     /gene="Stom"
                     /note="erythrocyte band 7 integral membrane protein"
                     /codon_start=1
                     /product="stomatin"
                     /protein_id="NP_001011965.1"
                     /db_xref="GeneID:296655"
                     /db_xref="RGD:1305109"
                     /translation="MSDKRQSGHVQSQRVPESFRDNSKAELGPCGWILVAVSFIFVLI
                     TFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFD
                     IPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNALGTKNL
                     SQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREAR
                     AKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDML
                     QGIMGSHH"
     exon            97..200
                     /gene="Stom"
                     /inference="alignment:Splign:2.1.0"
     exon            201..273
                     /gene="Stom"
                     /inference="alignment:Splign:2.1.0"
     exon            274..356
                     /gene="Stom"
                     /inference="alignment:Splign:2.1.0"
     exon            357..560
                     /gene="Stom"
                     /inference="alignment:Splign:2.1.0"
     exon            561..695
                     /gene="Stom"
                     /inference="alignment:Splign:2.1.0"
     exon            696..1764
                     /gene="Stom"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgacgccgt caagagcgac tccgactcca gcagtatgtc tgacaaacgc cagtccggcc
       61 atgtccagtc tcagcgggtc cccgagtcct tcagggataa ttccaaggca gaactgggac
      121 catgtggatg gattttggtg gctgtctcgt tcatcttcgt gcttataact ttcccaatat
      181 caatttggat ttgcataaag attgtgaagg agtatgaaag agtgatcatc ttcagactgg
      241 gccgcatttt gcaaggtggc gccaaaggac ctgggttgtt tttcatcctg ccgtgcactg
      301 acagcttcat caaggtggac atgaggacca tctccttcga tattccgcca caggaggtgc
      361 tcactaagga ctcggtgacc atcagcgtgg atggtgtggt ctattaccgt gttcagaacg
      421 caaccctggc tgtggcaaat atcaccaatg cagattcggc aacccgtctt ttggcgcaaa
      481 ctaccctcag gaatgcgctg ggcaccaaga acctgtctca gatcctctct gacagagaag
      541 agatcgcaca ccacatgcag agtacgctgg atgacgccac agatgactgg ggaataaagg
      601 tcgagcgtgt ggagattaag gacgtgaagc tgccagtaca gctccagaga gccatggctg
      661 cagaggcaga agccgcccgg gaggctagag ccaaggtgat tgcagccgaa ggggaaatga
      721 atgcatccag ggctctgaaa gaagcatcca tggttatcac ggagtctcct gctgcccttc
      781 agctccggta ccttcaaacc ctgaccacta tcgctgcgga gaaaaactcc accattgtct
      841 tccctctgcc catcgacatg ttgcagggca tcatgggttc ccaccactga gcagtccagc
      901 tctatgggag agctgtgctg agtccttccc agggtaaaga ggggacaaag ttagccttta
      961 actctcgggg agattagctg aaagcttgac tgtccccctc cctctccttt cctgtatgtg
     1021 cactgtaggg gctcttagaa tgggcaggga tcataaaagc agatgaagag actcgctctg
     1081 gagccaggag tgcagctcag ttgcagagca ctggcttagc ccgttcaagg ctcagggctt
     1141 catcctcagc accaacaaat aaacaaatag gcaagtcagg gaagggacgc gtctgagccc
     1201 aggtaaacac tctgtgacac tgaagaactg tgccacccac ttctctggct gcctgtgcct
     1261 tcccttcagg ggatccttag gatcgttttg ttttgttttg agatagggtt tcttagagta
     1321 gccttggctg tcctggcctt gaactcagag atccccctgc ctctgcctcc ccagtgctgg
     1381 gactaaaggt gtgggccacc accacctctc cctttaggaa atcttaagga aggacatttc
     1441 cccaaagttc atccacccac tctaatcctc tccctcctcc tgcttgatcc tgtcagagcc
     1501 aacaaaaagg ctcacgctgg cccttccaag accgaaggtc actcctgtca tagtcctttt
     1561 gaaaatagtt gcagttttta aaaaccgtct tgggcctccg ccccacaacc taatgatccc
     1621 tgtgtgtggc cttgtttaaa gcagtgaatc tctgccacag gagtgctccc ttctctctct
     1681 cgcatatttt catggatcag gtttttaaat cgttttgaat tttaaaaata actttgagtt
     1741 ctatcaataa actttatgtc cattaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
