LOCUS       NM_001395145             945 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus stathmin 3 (Stmn3), mRNA.
ACCESSION   NM_001395145
VERSION     NM_001395145.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  AUTHORS   Devaux,S., Poulain,F.E., Devignot,V., Lachkar,S., Irinopoulou,T.
            and Sobel,A.
  TITLE     Specific serine-proline phosphorylation and glycogen synthase
            kinase 3beta-directed subcellular targeting of stathmin 3/Sclip in
            neurons
  JOURNAL   J Biol Chem 287 (26), 22341-22353 (2012)
   PUBMED   22577147
  REMARK    GeneRIF: Specific serine-proline phosphorylation and glycogen
            synthase kinase 3beta-directed subcellular targeting of stathmin
            3/Sclip in neurons
REFERENCE   3  (bases 1 to 945)
  AUTHORS   Levy,A.D., Devignot,V., Fukata,Y., Fukata,M., Sobel,A. and
            Chauvin,S.
  TITLE     Subcellular Golgi localization of stathmin family proteins is
            promoted by a specific set of DHHC palmitoyl transferases
  JOURNAL   Mol Biol Cell 22 (11), 1930-1942 (2011)
   PUBMED   21471001
  REMARK    GeneRIF: palmitoylation of stathmins 2 and 3 likely occurs at the
            Golgi and is crucial for their specific subcellular localization
            and trafficking
REFERENCE   4  (bases 1 to 945)
  AUTHORS   Poulain,F.E., Chauvin,S., Wehrle,R., Desclaux,M., Mallet,J.,
            Vodjdani,G., Dusart,I. and Sobel,A.
  TITLE     SCLIP is crucial for the formation and development of the Purkinje
            cell dendritic arbor
  JOURNAL   J Neurosci 28 (29), 7387-7398 (2008)
   PUBMED   18632943
  REMARK    GeneRIF: SCLIP specifically accumulates in the growing dendrites of
            Purkinje cells (PC)during cerebellar development and is critical
            for both the formation and development of PC dendritic arbors at
            early and late stages of postnatal dendritogenesis.
REFERENCE   5  (bases 1 to 945)
  AUTHORS   Poulain,F.E. and Sobel,A.
  TITLE     The 'SCG10-LIke Protein' SCLIP is a novel regulator of axonal
            branching in hippocampal neurons, unlike SCG10
  JOURNAL   Mol Cell Neurosci 34 (2), 137-146 (2007)
   PUBMED   17145186
  REMARK    GeneRIF: A novel function for SCLIP in axonal morphogenesis, our
            results demonstrate for the first time that stathmin family
            proteins fulfill different and complementary roles during neuronal
            differentiation.
REFERENCE   6  (bases 1 to 945)
  AUTHORS   Baldassa,S., Gnesutta,N., Fascio,U., Sturani,E. and Zippel,R.
  TITLE     SCLIP, a microtubule-destabilizing factor, interacts with RasGRF1
            and inhibits its ability to promote Rac activation and neurite
            outgrowth
  JOURNAL   J Biol Chem 282 (4), 2333-2345 (2007)
   PUBMED   17135267
REFERENCE   7  (bases 1 to 945)
  AUTHORS   Kang,S.W., Shin,Y.J., Shim,Y.J., Jeong,S.Y., Park,I.S. and Min,B.H.
  TITLE     Clusterin interacts with SCLIP (SCG10-like protein) and promotes
            neurite outgrowth of PC12 cells
  JOURNAL   Exp Cell Res 309 (2), 305-315 (2005)
   PUBMED   16038898
  REMARK    GeneRIF: Clusterin interacts with SCLIP in PC12 cells and the
            interaction may act as an important modulator during neuronal
            differentiation.
REFERENCE   8  (bases 1 to 945)
  AUTHORS   Ozon,S., El Mestikawy,S. and Sobel,A.
  TITLE     Differential, regional, and cellular expression of the stathmin
            family transcripts in the adult rat brain
  JOURNAL   J Neurosci Res 56 (5), 553-564 (1999)
   PUBMED   10369222
REFERENCE   9  (bases 1 to 945)
  AUTHORS   Gavet,O., Ozon,S., Manceau,V., Lawler,S., Curmi,P. and Sobel,A.
  TITLE     The stathmin phosphoprotein family: intracellular localization and
            effects on the microtubule network
  JOURNAL   J Cell Sci 111 (Pt 22), 3333-3346 (1998)
   PUBMED   9788875
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ211987.1, FQ213831.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840110, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               JAXUCZ010000003.1  188802382-188802494 c
            114-209             JAXUCZ010000003.1  188797115-188797210 c
            210-385             JAXUCZ010000003.1  188796689-188796864 c
            386-577             JAXUCZ010000003.1  188795192-188795383 c
            578-945             JAXUCZ010000003.1  188794358-188794725 c
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..945
                     /gene="Stmn3"
                     /gene_synonym="Sclip"
                     /note="stathmin 3"
                     /db_xref="GeneID:29246"
                     /db_xref="RGD:3628"
     exon            1..113
                     /gene="Stmn3"
                     /gene_synonym="Sclip"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..637
                     /gene="Stmn3"
                     /gene_synonym="Sclip"
                     /note="SCG10-like protein; scgn10 like-protein;
                     stathmin-like 3"
                     /codon_start=1
                     /product="stathmin-3"
                     /protein_id="NP_001382074.1"
                     /db_xref="GeneID:29246"
                     /db_xref="RGD:3628"
                     /translation="MASTVSAYKEKMKELSVLSLICSCFYSQPHPNTIYQYGDMEVKQ
                     LDKRASGQSFEVILKSPSDLSPESPVLSSPPKRKDASLEELQKRLEAAEERRKTQEAQ
                     VLKQLAERREHEREVLHKALEENNNFSRLAEEKLNYKMELSKEIREAHLAALRERLRE
                     KELHAAEVRRNKEQREEMSG"
     exon            114..209
                     /gene="Stmn3"
                     /gene_synonym="Sclip"
                     /inference="alignment:Splign:2.1.0"
     exon            210..385
                     /gene="Stmn3"
                     /gene_synonym="Sclip"
                     /inference="alignment:Splign:2.1.0"
     exon            386..577
                     /gene="Stmn3"
                     /gene_synonym="Sclip"
                     /inference="alignment:Splign:2.1.0"
     exon            578..945
                     /gene="Stmn3"
                     /gene_synonym="Sclip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcccctcca cagcattgca gcattcgcag actgcagctc ccagacgccg cccgcatccc
       61 tccggccgcc gaagccccag ccgcctccag caccatggcc agcaccgtat ctgcctacaa
      121 ggagaagatg aaggagctat ctgtgctgtc gctcatctgt tcctgcttct actcgcagcc
      181 tcacccgaac accatctacc agtatgggga tatggaagtg aagcagctgg ataagcgggc
      241 ctctggccag agcttcgagg tcatcctcaa gtctccttct gacctatctc cagagagccc
      301 tgtgctctct tctcctccca agaggaagga tgcttccttg gaagagctgc agaagcggct
      361 ggaggcagct gaggagcgga ggaagactca ggaggctcag gtgctgaagc agctggcaga
      421 gcgacgtgag catgagcggg aggtgctgca caaggcgctg gaagaaaaca ataactttag
      481 ccgcctggcg gaggagaagc tcaactacaa gatggagctg agcaaggaga ttcgcgaggc
      541 gcacctggcg gcgctgcgcg agcggctgcg tgagaaggaa ctgcacgctg ctgaggtgcg
      601 caggaacaag gagcagcggg aggaaatgtc tggctaaaga gcactggacc aagcagcaac
      661 aagaacattt tccggttttg tttttgtttt caattctgtc tagatgcgaa ttttgtgcct
      721 gctcctatct gctcccctgt acccccagct tcctgctttt ctcccacatt ctgaactgtc
      781 cagtccttgt gatgtgtctg accttggact cttcctgaag gagctcccta ggcaggaata
      841 tggtccccta ttcagacact aggccaggtg tgactggggc tctcttagtg gccctcttag
      901 tggatgtgtt ggcaacctta ataaatctag tggcagtggc acaaa
//
