LOCUS       NM_017166               1039 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus stathmin 1 (Stmn1), mRNA.
ACCESSION   NM_017166
VERSION     NM_017166.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1039)
  AUTHORS   Shan,W., Han,F., Xu,Y. and Shi,Y.
  TITLE     Stathmin Regulates Spatiotemporal Variation in the Memory Loop in
            Single-Prolonged Stress Rats
  JOURNAL   J Mol Neurosci 70 (4), 576-589 (2020)
   PUBMED   31933182
  REMARK    GeneRIF: Stathmin Regulates Spatiotemporal Variation in the Memory
            Loop in Single-Prolonged Stress Rats.
REFERENCE   2  (bases 1 to 1039)
  AUTHORS   Imura,S., Yamada,S., Saito,Y.U., Iwahashi,S., Arakawa,Y.,
            Ikemoto,T., Morine,Y., Utsunomiya,T. and Shimada,M.
  TITLE     miR-223 and Stathmin-1 Expression in Non-tumor Liver Tissue of
            Patients with Hepatocellular Carcinoma
  JOURNAL   Anticancer Res 37 (10), 5877-5883 (2017)
   PUBMED   28982915
REFERENCE   3  (bases 1 to 1039)
  AUTHORS   Fuller,H.R., Slade,R., Jovanov-Milosevic,N., Babic,M., Sedmak,G.,
            Simic,G., Fuszard,M.A., Shirran,S.L., Botting,C.H. and Gates,M.A.
  TITLE     Stathmin is enriched in the developing corticospinal tract
  JOURNAL   Mol Cell Neurosci 69, 12-21 (2015)
   PUBMED   26370173
  REMARK    GeneRIF: Stathmin is enriched in the developing corticospinal tract
REFERENCE   4  (bases 1 to 1039)
  AUTHORS   Zhao,E., Amir,M., Lin,Y. and Czaja,M.J.
  TITLE     Stathmin mediates hepatocyte resistance to death from oxidative
            stress by down regulating JNK
  JOURNAL   PLoS One 9 (10), e109750 (2014)
   PUBMED   25285524
  REMARK    GeneRIF: Stathmin therefore mediates hepatocyte resistance to death
            from oxidative stress by down regulating JNK and maintaining
            mitochondrial integrity
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1039)
  AUTHORS   Tian,X., Tian,Y., Moldobaeva,N., Sarich,N. and Birukova,A.A.
  TITLE     Microtubule dynamics control HGF-induced lung endothelial barrier
            enhancement
  JOURNAL   PLoS One 9 (9), e105912 (2014)
   PUBMED   25198505
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1039)
  AUTHORS   Howell,B., Larsson,N., Gullberg,M. and Cassimeris,L.
  TITLE     Dissociation of the tubulin-sequestering and microtubule
            catastrophe-promoting activities of oncoprotein 18/stathmin
  JOURNAL   Mol Biol Cell 10 (1), 105-118 (1999)
   PUBMED   9880330
REFERENCE   7  (bases 1 to 1039)
  AUTHORS   Gavet,O., Ozon,S., Manceau,V., Lawler,S., Curmi,P. and Sobel,A.
  TITLE     The stathmin phosphoprotein family: intracellular localization and
            effects on the microtubule network
  JOURNAL   J Cell Sci 111 (Pt 22), 3333-3346 (1998)
   PUBMED   9788875
REFERENCE   8  (bases 1 to 1039)
  AUTHORS   Larsson,N., Marklund,U., Gradin,H.M., Brattsand,G. and Gullberg,M.
  TITLE     Control of microtubule dynamics by oncoprotein 18: dissection of
            the regulatory role of multisite phosphorylation during mitosis
  JOURNAL   Mol Cell Biol 17 (9), 5530-5539 (1997)
   PUBMED   9271428
REFERENCE   9  (bases 1 to 1039)
  AUTHORS   Doye,V., Soubrier,F., Bauw,G., Boutterin,M.C., Beretta,L.,
            Koppel,J., Vandekerckhove,J. and Sobel,A.
  TITLE     A single cDNA encodes two isoforms of stathmin, a developmentally
            regulated neuron-enriched phosphoprotein
  JOURNAL   J Biol Chem 264 (21), 12134-12137 (1989)
   PUBMED   2745432
REFERENCE   10 (bases 1 to 1039)
  AUTHORS   Schubart,U.K., Banerjee,M.D. and Eng,J.
  TITLE     Homology between the cDNAs encoding phosphoprotein p19 and SCG10
            reveals a novel mammalian gene family preferentially expressed in
            developing brain
  JOURNAL   DNA 8 (6), 389-398 (1989)
   PUBMED   2776625
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1 and J04979.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by NM_017166.3.
            
            On Nov 20, 2020 this sequence version replaced NM_017166.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: J04979.1, SRR22399489.1343446.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 JAXUCZ010000005.1  151965179-151965181
            4-199               J04979.1           14-209
            200-520             JAXUCZ010000005.1  151970490-151970810
            521-1009            J04979.1           211-699
            1010-1330           JAXUCZ010000005.1  151970490-151970810
            1331-1359           J04979.1           1022-1050
FEATURES             Location/Qualifiers
     source          1..1039
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1039
                     /gene="Stmn1"
                     /gene_synonym="Lap18; OP18; PP17; PP19; PR22; prosolin;
                     SMN"
                     /note="stathmin 1"
                     /db_xref="GeneID:29332"
                     /db_xref="RGD:2992"
     exon            1..98
                     /gene="Stmn1"
                     /gene_synonym="Lap18; OP18; PP17; PP19; PR22; prosolin;
                     SMN"
                     /inference="alignment:Splign:2.1.0"
     exon            99..171
                     /gene="Stmn1"
                     /gene_synonym="Lap18; OP18; PP17; PP19; PR22; prosolin;
                     SMN"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..608
                     /gene="Stmn1"
                     /gene_synonym="Lap18; OP18; PP17; PP19; PR22; prosolin;
                     SMN"
                     /note="metablastin; oncoprotein 18; phosphoprotein p19;
                     leukemia-associated phosphoprotein p18"
                     /codon_start=1
                     /product="stathmin"
                     /protein_id="NP_058862.1"
                     /db_xref="GeneID:29332"
                     /db_xref="RGD:2992"
                     /translation="MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKD
                     LSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLT
                     HKMEANKENREAQMAAKLERLREKDKHVEEVRKNKESKDPADETEAD"
     exon            172..344
                     /gene="Stmn1"
                     /gene_synonym="Lap18; OP18; PP17; PP19; PR22; prosolin;
                     SMN"
                     /inference="alignment:Splign:2.1.0"
     exon            345..536
                     /gene="Stmn1"
                     /gene_synonym="Lap18; OP18; PP17; PP19; PR22; prosolin;
                     SMN"
                     /inference="alignment:Splign:2.1.0"
     exon            537..1039
                     /gene="Stmn1"
                     /gene_synonym="Lap18; OP18; PP17; PP19; PR22; prosolin;
                     SMN"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttggctta ggcggaggcg acggcagggt agggagcagc cgggaacgcg gcgagcccct
       61 agccggggac acgggacggg cggagacctc gagccctggg ctttccttgc cagtggattg
      121 tgtagagtgt acagccagtc tcttgtcttc tgtccaacat ggcatcttct gatattcagg
      181 tgaaagagct ggagaagcgt gcttccggcc aggcttttga gctgattctc agccctcgat
      241 caaaagaatc tgtccccgag ttcccccttt cccccccaaa gaagaaggat ctttccctgg
      301 aggaaattca gaagaaatta gaagctgcag aagaaagacg caagtctcat gaagcagaag
      361 tcttgaagca gctcgctgag aagcgggagc atgaaaaaga agtgctccag aaagccattg
      421 aggagaacaa caacttcagc aaaatggcag aggagaaact gacccacaaa atggaggcta
      481 acaaagagaa ccgggaggcg caaatggctg ccaagctgga gcgtttgcga gagaaggaca
      541 agcacgttga agaggtgcgg aagaacaaag aatccaaaga ccccgcggac gagaccgagg
      601 ctgactaagt tgttccgaga actgactttc tccccgaccc cttcctaaat atccaaagac
      661 tgtactggcc agtgtcattt actttttccc tcctgacaaa tattctagaa gctgatgtag
      721 gaccgtatag gtagatccag accgtgagat gttttagggg ctcaagggga gaaactgaaa
      781 gtgttttgct cttttttaaa gtgttggtct ttctaacgta gctatttttc tcgttgcatc
      841 ttttcctctc gggcacactc ggtgtgctgg gttaatggct agtgctgtat tgactgtgga
      901 agacgttcgt gaagagtatg tagtggcttc ttccaaccca ttagatgctg agtatctgtt
      961 cactttgcga tcccaattct gtcccaatct caccagatgc tactgtactt gaatggttaa
     1021 taaactgcac agtgctgtt
//
