LOCUS       NM_138911               2094 bp    mRNA    linear   ROD 08-APR-2024
DEFINITION  Rattus norvegicus stress-induced phosphoprotein 1 (Stip1), mRNA.
ACCESSION   NM_138911
VERSION     NM_138911.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2094)
  AUTHORS   An,L., Gao,H., Zhong,Y., Liu,Y., Cao,Y., Yi,J., Huang,X., Wen,C.,
            Tong,R., Pan,Z., Yan,X., Liu,M., Wang,S., Wu,H. and Hu,T.
  TITLE     The potential roles of stress-induced phosphoprotein 1 and connexin
            43 in rats with reperfusion arrhythmia
  JOURNAL   Immun Inflamm Dis 11 (10), e852 (2023)
   PUBMED   37904692
  REMARK    GeneRIF: The potential roles of stress-induced phosphoprotein 1 and
            connexin 43 in rats with reperfusion arrhythmia.
REFERENCE   2  (bases 1 to 2094)
  AUTHORS   Jin,H., Ge,X., Huan,Z., Yao,H., Xu,C. and Cai,J.
  TITLE     Stress-induced phosphoprotein 1 restrains spinal cord
            ischaemia-reperfusion injury by modulating NF-kappaB signalling
  JOURNAL   J Cell Mol Med 25 (24), 11075-11084 (2021)
   PUBMED   34734476
  REMARK    GeneRIF: Stress-induced phosphoprotein 1 restrains spinal cord
            ischaemia-reperfusion injury by modulating NF-kappaB signalling.
REFERENCE   3  (bases 1 to 2094)
  AUTHORS   Aiello,F.B., Guszczynski,T., Li,W., Hixon,J.A., Jiang,Q.,
            Hodge,D.L., Massignan,T., Di Lisio,C., Merchant,A., Procopio,A.D.,
            Bonetto,V. and Durum,S.K.
  TITLE     IL-7-induced phosphorylation of the adaptor Crk-like and other
            targets
  JOURNAL   Cell Signal 47, 131-141 (2018)
   PUBMED   29581031
REFERENCE   4  (bases 1 to 2094)
  AUTHORS   Woodford,M.R., Sager,R.A., Marris,E., Dunn,D.M., Blanden,A.R.,
            Murphy,R.L., Rensing,N., Shapiro,O., Panaretou,B., Prodromou,C.,
            Loh,S.N., Gutmann,D.H., Bourboulia,D., Bratslavsky,G., Wong,M. and
            Mollapour,M.
  TITLE     Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates
            folding of kinase and non-kinase clients
  JOURNAL   EMBO J 36 (24), 3650-3665 (2017)
   PUBMED   29127155
REFERENCE   5  (bases 1 to 2094)
  AUTHORS   Xilouri,M. and Stefanis,L.
  TITLE     Chaperone mediated autophagy to the rescue: A new-fangled target
            for the treatment of neurodegenerative diseases
  JOURNAL   Mol Cell Neurosci 66 (Pt A), 29-36 (2015)
   PUBMED   25724482
  REMARK    Review article
REFERENCE   6  (bases 1 to 2094)
  AUTHORS   Werner,H.B., Kuhlmann,K., Shen,S., Uecker,M., Schardt,A.,
            Dimova,K., Orfaniotou,F., Dhaunchak,A., Brinkmann,B.G., Mobius,W.,
            Guarente,L., Casaccia-Bonnefil,P., Jahn,O. and Nave,K.A.
  TITLE     Proteolipid protein is required for transport of sirtuin 2 into CNS
            myelin
  JOURNAL   J Neurosci 27 (29), 7717-7730 (2007)
   PUBMED   17634366
REFERENCE   7  (bases 1 to 2094)
  AUTHORS   Coitinho,A.S., Lopes,M.H., Hajj,G.N., Rossato,J.I., Freitas,A.R.,
            Castro,C.C., Cammarota,M., Brentani,R.R., Izquierdo,I. and
            Martins,V.R.
  TITLE     Short-term memory formation and long-term memory consolidation are
            enhanced by cellular prion association to stress-inducible protein
            1
  JOURNAL   Neurobiol Dis 26 (1), 282-290 (2007)
   PUBMED   17329112
  REMARK    GeneRIF: STI1 interaction with PrP(C) affects short-term memory
            formation and long-term memory consolidation
REFERENCE   8  (bases 1 to 2094)
  AUTHORS   Prescott,J. and Coetzee,G.A.
  TITLE     Molecular chaperones throughout the life cycle of the androgen
            receptor
  JOURNAL   Cancer Lett 231 (1), 12-19 (2006)
   PUBMED   16356826
  REMARK    Review article
REFERENCE   9  (bases 1 to 2094)
  AUTHORS   Pratt,W.B., Morishima,Y., Murphy,M. and Harrell,M.
  TITLE     Chaperoning of glucocorticoid receptors
  JOURNAL   Handb Exp Pharmacol (172), 111-138 (2006)
   PUBMED   16610357
  REMARK    Review article
REFERENCE   10 (bases 1 to 2094)
  AUTHORS   Demand,J., Luders,J. and Hohfeld,J.
  TITLE     The carboxy-terminal domain of Hsc70 provides binding sites for a
            distinct set of chaperone cofactors
  JOURNAL   Mol Cell Biol 18 (4), 2023-2028 (1998)
   PUBMED   9528774
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Mar 8, 2021 this sequence version replaced NM_138911.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061529.1, Y15068.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                JAXUCZ010000001.1  213657581-213657654 c
            75-284              JAXUCZ010000001.1  213653107-213653316 c
            285-426             JAXUCZ010000001.1  213652061-213652202 c
            427-568             JAXUCZ010000001.1  213651765-213651906 c
            569-737             JAXUCZ010000001.1  213650009-213650177 c
            738-864             JAXUCZ010000001.1  213645960-213646086 c
            865-967             JAXUCZ010000001.1  213645761-213645863 c
            968-1088            JAXUCZ010000001.1  213645525-213645645 c
            1089-1185           JAXUCZ010000001.1  213643453-213643549 c
            1186-1310           JAXUCZ010000001.1  213642570-213642694 c
            1311-1347           JAXUCZ010000001.1  213640247-213640283 c
            1348-1451           JAXUCZ010000001.1  213640002-213640105 c
            1452-1624           JAXUCZ010000001.1  213639633-213639805 c
            1625-2094           JAXUCZ010000001.1  213638641-213639110 c
FEATURES             Location/Qualifiers
     source          1..2094
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2094
                     /gene="Stip1"
                     /note="stress-induced phosphoprotein 1"
                     /db_xref="GeneID:192277"
                     /db_xref="RGD:621599"
     exon            1..74
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1697
                     /gene="Stip1"
                     /note="hop; STI1; hsc70/Hsp90-organizing protein;
                     stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
                     protein)"
                     /codon_start=1
                     /product="stress-induced-phosphoprotein 1"
                     /protein_id="NP_620266.1"
                     /db_xref="GeneID:192277"
                     /db_xref="RGD:621599"
                     /translation="MEQVNELKEKGNKALSAGNIDDALQCYSEAIKLDPQNHVLYSNR
                     SAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHE
                     ANNLQLKEGLQNMEARLAERKFMNPFNLPNLYQKLENDPRTRTLLSDPTYRELIEQLQ
                     NKPSDLGTKLQDPRVMTTLSVLLGVDLGSMDEEEEAATPPPPPPPKKEAKPEPMEEDL
                     PENKKQALKEKELGNDAYKKKDFDKALKHYDKAKELDPTNMTYITNQAAVHFEKGDYN
                     KCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEERYKDAIHFYNKSLAEHRTPD
                     VLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPR
                     DAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDV
                     YQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLIL
                     EQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR"
     exon            75..284
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            285..426
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            427..568
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            569..737
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            738..864
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            865..967
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1088
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1185
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1310
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1347
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1451
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1624
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..2094
                     /gene="Stip1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggcgcgt gcggttggga acgcggagcg gacgaattcg attcaacggg gttccgggcc
       61 aggctatgga gcaggtgaat gagctaaagg agaagggcaa taaggccctg agtgctggga
      121 acattgatga tgccttacag tgctactctg aggcaattaa actagatcct cagaaccatg
      181 tgctctatag caatcgctct gcagcctatg ccaagaaagg agactaccag aaggcgtatg
      241 aggacggttg caagactgtt gacctgaagc ctgactgggg caagggttat tcaagaaaag
      301 cagcagccct tgagttccta aaccggtttg aagaagccaa acgaacctat gaagaaggtt
      361 taaaacatga agccaataat ctacagctta aggaaggctt gcagaacatg gaggccaggt
      421 tggcagagag gaaatttatg aatcctttca acttgcctaa tctgtaccag aagttagaga
      481 atgatcccag gacaaggaca ctgctcagtg accccaccta cagggaactc atagagcaac
      541 tacagaacaa gccttcagac ctgggcacga aactccaaga tccccgggtc atgactactc
      601 tcagtgtcct ccttggagtt gatctgggca gtatggatga agaggaagag gcagcaacac
      661 ccccacctcc accccctcct aaaaaggagg ccaagccaga accaatggaa gaagatcttc
      721 cagagaataa gaaacaggct ctgaaagaaa aggagctggg aaatgatgcc tacaagaaga
      781 aagattttga caaggccctg aagcattatg acaaggccaa ggagctggac cctaccaata
      841 tgacttacat aactaatcaa gcagctgtgc actttgagaa gggcgactac aacaaatgcc
      901 gggagctctg tgagaaggcc attgaagtag gcagagagaa ccgagaggac taccgtcaga
      961 tcgccaaagc ttatgctcga attggcaatt cctatttcaa agaagaaagg tacaaggatg
     1021 ctatccattt ctacaacaag tctctggcag agcaccgaac cccagatgtg ctcaagaagt
     1081 gccagcaggc agagaaaatt ctgaaggaac aagagcgact ggcttatatc aaccctgatt
     1141 tggctttgga ggaaaagaat aagggcaatg agtgcttcca gaaaggggac tacccccagg
     1201 ccatgaagca ctatacagaa gccattaaaa ggaacccaag agatgccaaa ctatacagca
     1261 accgagccgc ctgctacacc aagctcctgg agtttcagct ggcactcaag gactgtgaag
     1321 agtgcatcca gctagagcca accttcatca agggttatac acggaaagca gctgccctgg
     1381 aagccatgaa ggactataca aaagccatgg atgtgtacca gaaggcatta gacctggact
     1441 ccagctgtaa ggaagcagca gatggttacc aacgctgtat gatggcacag tacaacagac
     1501 atgatagccc tgaggatgtg aaacggcggg ccatggctga ccctgaggta cagcagataa
     1561 tgagtgaccc agccatgagg ctcatcctgg agcagatgca aaaggacccc caagctctga
     1621 gcgaacactt aaagaatcct gtaatagcac agaagatcca gaagctgatg gatgtgggtc
     1681 tgatcgcaat tcggtgataa cttgcttttc ccctctcccc ttcgccgatg aggaaaggcg
     1741 agctgggacg gtggcaagca gtactgggca gaggggggag aagaaaggct tatctttata
     1801 tttatacatg cctacaagga agacagactc atccagtgcc acctcgggcc ctcccagcac
     1861 acgcatggtc ttttcactgc tgcccccaat tccgaatatc cttccctgcc cattcccagc
     1921 ctccccgtca ctgtctcagc tgcttcccta tagttggtta ttttttattt ggggcagtgg
     1981 gtgcatacgg ggaggggagg gtattcttcc caacctaagg tcccaactgt cttacttgtt
     2041 cttacccatg tcccccctca ataaaacaag ccagtcaggc gtggttatat gttg
//
