LOCUS       NM_001399206            5272 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus STIL, centriolar assembly protein (Stil), mRNA.
ACCESSION   NM_001399206 XM_039111179
VERSION     NM_001399206.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5272)
  AUTHORS   Arquint,C., Gabryjonczyk,A.M., Imseng,S., Bohm,R., Sauer,E.,
            Hiller,S., Nigg,E.A. and Maier,T.
  TITLE     STIL binding to Polo-box 3 of PLK4 regulates centriole duplication
  JOURNAL   Elife 4, e07888 (2015)
   PUBMED   26188084
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5272)
  AUTHORS   Shiratsuchi,G., Takaoka,K., Ashikawa,T., Hamada,H. and Kitagawa,D.
  TITLE     RBM14 prevents assembly of centriolar protein complexes and
            maintains mitotic spindle integrity
  JOURNAL   EMBO J 34 (1), 97-114 (2015)
   PUBMED   25385835
REFERENCE   3  (bases 1 to 5272)
  AUTHORS   Sun,L., Carr,A.L., Li,P., Lee,J., McGregor,M. and Li,L.
  TITLE     Characterization of the human oncogene SCL/TAL1 interrupting locus
            (Stil) mediated Sonic hedgehog (Shh) signaling transduction in
            proliferating mammalian dopaminergic neurons
  JOURNAL   Biochem Biophys Res Commun 449 (4), 444-448 (2014)
   PUBMED   24853807
  REMARK    GeneRIF: results provide direct evidence for the involvement of
            Stil in dopaminergic cell proliferation
REFERENCE   4  (bases 1 to 5272)
  AUTHORS   Vulprecht,J., David,A., Tibelius,A., Castiel,A., Konotop,G.,
            Liu,F., Bestvater,F., Raab,M.S., Zentgraf,H., Izraeli,S. and
            Kramer,A.
  TITLE     STIL is required for centriole duplication in human cells
  JOURNAL   J Cell Sci 125 (Pt 5), 1353-1362 (2012)
   PUBMED   22349705
REFERENCE   5  (bases 1 to 5272)
  AUTHORS   Tang,C.J., Lin,S.Y., Hsu,W.B., Lin,Y.N., Wu,C.T., Lin,Y.C.,
            Chang,C.W., Wu,K.S. and Tang,T.K.
  TITLE     The human microcephaly protein STIL interacts with CPAP and is
            required for procentriole formation
  JOURNAL   EMBO J 30 (23), 4790-4804 (2011)
   PUBMED   22020124
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5272)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   7  (bases 1 to 5272)
  AUTHORS   Campaner,S., Kaldis,P., Izraeli,S. and Kirsch,I.R.
  TITLE     Sil phosphorylation in a Pin1 binding domain affects the duration
            of the spindle checkpoint
  JOURNAL   Mol Cell Biol 25 (15), 6660-6672 (2005)
   PUBMED   16024801
REFERENCE   8  (bases 1 to 5272)
  AUTHORS   Izraeli,S., Lowe,L.A., Bertness,V.L., Good,D.J., Dorward,D.W.,
            Kirsch,I.R. and Kuehn,M.R.
  TITLE     The SIL gene is required for mouse embryonic axial development and
            left-right specification
  JOURNAL   Nature 399 (6737), 691-694 (1999)
   PUBMED   10385121
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jan 4, 2022 this sequence version replaced XM_039111179.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.22498.1,
                                           SRR26643429.20379.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-228               JAXUCZ010000005.1  133757631-133757858
            229-313             JAXUCZ010000005.1  133760417-133760501
            314-421             JAXUCZ010000005.1  133762501-133762608
            422-534             JAXUCZ010000005.1  133777722-133777834
            535-722             JAXUCZ010000005.1  133778107-133778294
            723-970             JAXUCZ010000005.1  133780230-133780477
            971-1054            JAXUCZ010000005.1  133781026-133781109
            1055-1141           JAXUCZ010000005.1  133781816-133781902
            1142-1292           JAXUCZ010000005.1  133784210-133784360
            1293-1408           JAXUCZ010000005.1  133786179-133786294
            1409-1523           JAXUCZ010000005.1  133791024-133791138
            1524-2462           JAXUCZ010000005.1  133793678-133794616
            2463-2631           JAXUCZ010000005.1  133798173-133798341
            2632-2860           JAXUCZ010000005.1  133801017-133801245
            2861-3047           JAXUCZ010000005.1  133805637-133805823
            3048-3298           JAXUCZ010000005.1  133806358-133806608
            3299-5272           JAXUCZ010000005.1  133808520-133810493
FEATURES             Location/Qualifiers
     source          1..5272
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q35"
     gene            1..5272
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /note="STIL, centriolar assembly protein"
                     /db_xref="GeneID:313506"
                     /db_xref="RGD:1304972"
     exon            1..228
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            229..313
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     CDS             303..4094
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /note="Tal1 interrupting locus; Scl/Tal1 interrupting
                     locus"
                     /codon_start=1
                     /product="SCL-interrupting locus protein"
                     /protein_id="NP_001386135.1"
                     /db_xref="GeneID:313506"
                     /db_xref="RGD:1304972"
                     /translation="MNTRFPSSKMVPFHFPPSKLALWNPMPIGECIYLHLSYYRKPKL
                     TVTEKAIRLAYRHAKQSKKNVPCFLLGSLTVDEDEEGVTLTIDRFDPGRETRECLERT
                     PTAALPGDFLIPCKVHTQGLCSRDTKVHNADDFSSALKALQHHVCSKDLLDCGKLLSL
                     RAQITPRESLGGVDLNLQWTAVTLANPFKCIPVKPIPIIPTALARNLSSSLNISQVQG
                     TCKHGYITMDETRKLLLLLESDPKVYSLPLVGIWLSGIIHIYSPQVWACCLRYMFSSS
                     IQERVFSESGNFIIVLYSLTHKEPEFYECLPCDSRTPELQFQLLTNKETFHLFKNVEP
                     SSKNLMHFELSAESQDAEAEAKLFSKISKDLSVKRASQKVSPGKIPINKRDTDLEDED
                     FSPRPIPSPHPVSQKISKIQPSVPELSLVLDNNFTESSNPSKPVEVMAVENPLLIKPS
                     QPELCDDKHSSEANTGEPFLRGLPNQLSQDTALRQCRGKQSSTCMKESLPFRSTNAKP
                     SLNAPSPDVAEKLQAVSAGSMSKEDYPVRPSLLDSRQPSLAPQAHPHNLVFSPHNSTR
                     PMELQVPTPSLPSYYSTNVCSCCQHHGHIQYSTINSWQGNTVGSVQDLRSEALPKHAF
                     FHSSGCPSLCPNAIYSSSSPVTMKPQGGVDTYSPHSNGEPSPVAGPSHVDSCVPHPCA
                     VCMHTPTTAPDNGMMGLSPDAYRFVTEQDRQLRLLQAQIQRLLEAQSLDPGSHKSVAT
                     AEDSVKAARQMELVSVEAQSSPGLHMRKSVSIAVSTGASLFWNAAGDDQEHDAQLKQD
                     DTKISSEDMNFSVDINNEATSPPGSASSLKAVDIPSFEESNPAVEEFNQPLPESNSSE
                     QRKEPDVPVFFPNALLAESVSMCLQTAPAEGASNSTESPQGTKVEPFGPSDNKIYQDL
                     LGQVNHLLSNSSQETDQPPTRAVVINHECTKTQNAHHARKKRHTSGLVDTDCVLSATI
                     KQLRSLGVKIDSPTKVKKSAQKVDHASVLACISPEAVISGLNYMSFGNIGMSSLSPTG
                     VDLSMEANAIALRYLSENQLSQLSLARSNQNHCDSSLGLLHINSDKSSVGLSLVSPSN
                     MSFATKKYMKRYGLLQSSDNSEDEDEEEPPGHSDSESNRVLNRNPACKPAQCGPERAP
                     SRNACETAQCSNGGSGDTHTDVPVLRNITNQAQQPRAAEHLTQDSAVSLRNLKPHPAV
                     NLRTGKAEFTRHPEKENERDIAVFPELSQSPETLKQMNSMNSVGTFLDVKRLRQLPKL
                     F"
     exon            314..421
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            422..534
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            535..722
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            723..970
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1054
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1141
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1292
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1408
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1523
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..2462
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            2463..2631
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            2632..2860
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            2861..3047
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            3048..3298
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
     exon            3299..5272
                     /gene="Stil"
                     /gene_synonym="Sil"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgcgccct tcgttttcct cctgccggcg cttaccgcct cggttcccgc gaccccaacg
       61 tcccagaggc ggggccgcag ttatctgaga cgctacttgg agccttctgc gtgcccaaca
      121 aacgggccca acaaccaaaa ccctagcttg gcggcggccg tgacaatagc gcgggtggat
      181 cttcgtgctc ctggttcccc gaggcgccct ccgggcccgg gaagcacagt actgaggatt
      241 acagagtgaa taaatcactc accaaatata gagcctgtag ttcctccagc ctgcagttcc
      301 agatgaatac caggtttcct tcaagcaaga tggtaccttt ccactttcct ccatcaaaat
      361 tggcactttg gaacccaatg ccaattggag agtgtatcta cctacatctc agctactaca
      421 gaaagccaaa gcttacggta actgaaaagg ccatccgcct ggcttaccgt catgctaagc
      481 agagcaaaaa aaatgtgccg tgcttcctac ttggctctct cacagtggat gaagacgaag
      541 aaggggtgac cttgaccata gatcgctttg atcctggtag agaaacccgt gaatgcttag
      601 aaagaactcc tactgctgct cttcctggag attttttgat cccctgcaaa gttcatactc
      661 aaggactttg ttcaagagat acgaaagttc ataatgcaga tgacttcagt tcagctttaa
      721 aggctttaca gcaccatgtg tgcagcaaag acctcttgga ctgtgggaag ctgctttcct
      781 tacgagccca aatcaccccc agggagagtt tgggcggtgt ggatcttaat ttgcagtgga
      841 cagcagtgac tctagcaaat cctttcaagt gtatacctgt gaagcccatc cccattattc
      901 ctacagcact ggcaagaaac ttaagtagta gtctgaatat ttctcaagtt cagggaacct
      961 gtaagcacgg atatattact atggatgaaa cacgcaaatt gttacttttg ttggaatcag
     1021 atcccaaggt ttattctcta ccattagtgg gaatctggct gtctggaatt atacatatct
     1081 atagccctca ggtatgggct tgctgcttga gatacatgtt cagttcttct attcaggaaa
     1141 gggttttttc agaatctgga aatttcatca tagttcttta ttcattgaca cataaggaac
     1201 ctgagtttta tgagtgcctg ccttgtgaca gtaggacacc cgagctgcag tttcagttac
     1261 tgaccaacaa ggagactttt catcttttca agaatgttga accttctagc aaaaatctaa
     1321 tgcattttga actcagtgct gagagtcaag atgctgaagc ggaggccaag ctttttagca
     1381 agatttccaa ggatctttca gttaagagag cctcccaaaa agtatctcct gggaaaatac
     1441 caataaataa gcgtgacact gaccttgaag atgaagactt ttctccaaga ccgattccca
     1501 gtcctcaccc agtgagtcaa aagatttcta agatccagcc atctgttcct gaactttcgc
     1561 ttgtattaga caacaacttc acagaatcaa gtaacccgtc taagccagtg gaagtgatgg
     1621 ctgtggagaa tcctttgttg attaagccct cacagcctga gctttgtgat gacaaacaca
     1681 gctcagaagc taacactggg gaacctttcc tgaggggact gccaaatcag ttaagccagg
     1741 acactgcttt aagacagtgc agagggaagc agtcatctac ctgtatgaaa gagagcctcc
     1801 ctttcaggag cactaatgct aagccttctc tcaatgcgcc atctcctgat gtagctgaga
     1861 aacttcaagc agtgtctgca gggagcatgt caaaggaaga ctaccccgtg agaccttcct
     1921 tactggactc taggcagccc tctcttgctc cacaagccca cccacacaat cttgtttttt
     1981 caccccataa ttcaacaaga ccaatggagc ttcaagtacc cactccttca ttaccatcct
     2041 actattccac gaatgtctgc agctgttgtc agcatcatgg ccatattcag tatagtacaa
     2101 taaattcttg gcagggaaat acagtagggt ctgttcaaga cctccgatct gaagcccttc
     2161 caaaacatgc attctttcac tcaagtggat gtccatctct gtgtcctaat gccatctact
     2221 catcaagtag tcctgttacc atgaagcctc aaggaggtgt ggacacctat tctccccaca
     2281 gcaatggaga accgtcccct gtggcaggac cttcacatgt ggactcgtgt gtgccacatc
     2341 cctgtgccgt gtgcatgcac acacccacta cagccccaga caatggcatg atgggactgt
     2401 ctcctgatgc gtatcgcttt gtcacagaac aggaccggca gctgagacta cttcaggcac
     2461 agattcagcg cttattagaa gcacagtctc tagatcctgg ctcccataag tcagtagcca
     2521 ctgcggaaga ctctgtgaaa gctgcaagac agatggagct ggtttccgtg gaagcacagt
     2581 cttcacctgg cttgcacatg agaaaaagtg taagcattgc tgtgagcaca ggtgctagct
     2641 tgttttggaa cgcagcaggt gatgatcaag agcatgacgc acagctgaag caagatgata
     2701 ccaagatttc cagtgaagac atgaattttt ctgtagatat taataatgaa gcgacaagtc
     2761 ctccaggcag cgcatcttcc ttaaaagcag ttgacattcc tagttttgaa gaaagcaacc
     2821 ctgctgtgga agaatttaat caaccacttc ctgaatccaa ctcttcagag cagagaaaag
     2881 agcctgatgt tcctgtgttc ttcccaaatg ctttgctggc tgaaagtgtg agcatgtgct
     2941 tacagactgc gccagcagag ggagccagta acagcactga atcaccacag ggaacaaaag
     3001 ttgagccctt tgggccatca gataacaaaa tttaccagga cttgttgggt caggtgaacc
     3061 acctcctgag taactcctcc caggaaacgg atcaaccacc taccagagca gtagttatca
     3121 accatgagtg caccaagacc caaaatgctc accatgcaag gaaaaaaaga cacacttcag
     3181 gactggtgga cacagattgt gtactcagtg caactattaa acagctaagg agcctaggag
     3241 tgaaaattga ttctcccact aaagtgaaga aaagtgccca gaaggtggat catgccagtg
     3301 ttttggcatg catcagccca gaagcagtga tctctggatt gaactacatg tcgtttggta
     3361 acattggcat gagcagctta agtcccactg gtgtggattt gagcatggaa gcaaatgcca
     3421 tagctctgag gtacttgagt gaaaaccagc tgtcacaact gtcccttgct cgatcaaacc
     3481 agaatcactg tgactcgtct ctcggccttc tacatattaa ttcagacaaa agctcagtgg
     3541 ggcttagctt agtttcacca agcaacatgt catttgcaac caaaaaatac atgaagagat
     3601 acggactctt acaaagcagt gacaatagcg aggatgagga tgaagaggag cctcccggcc
     3661 attcggacag tgagagcaac cgtgtgttga acagaaaccc agcgtgcaaa ccagcacagt
     3721 gtggtcctga gagagcgcct tctcggaatg cctgtgagac agctcagtgc tctaacggtg
     3781 gctctgggga cacgcacaca gatgtgccag tattgagaaa catcacaaac caagctcagc
     3841 agccgagagc agcagagcac ctgactcaag actctgctgt ctcattgagg aatcttaagc
     3901 cacacccagc agtaaacctc cgaactggaa aagcagaatt tactcgtcat cccgagaagg
     3961 aaaatgaaag agacattgcc gtttttcctg aactctcgca gtctcctgag actttaaagc
     4021 aaatgaatag catgaattct gtgggcacct tcttagatgt aaagcgtctt agacagttac
     4081 caaagttatt ctaactcttc atttctcttt tgtggtgtgt gtgaggacta gccctgtact
     4141 gatagcactt aaggaggcca gacctttggg atatgtttgt ttttcaagac agggtttctc
     4201 tgtgtaaccc tggctgtcct gaaactcact ccatagacca ggatggcctc aaactcacag
     4261 agatccacct gcctctgctt tccaggtgct aggtaggatt aaggttaaag gcttgcatca
     4321 tcattgcctg gccacgacct ttgtatgacc tttgggattt ctaatacctc tgagagtctt
     4381 ttccctgtta gtagctaatt aacattggtt tgagggggtt tgacccagtt gtgagatggc
     4441 tgattagagg gaaagctggg ttcattcagc atcattgaac ctaaaacaga ggcaaaacaa
     4501 ctcagaagat caggtgctgc agccaatcag gttcagatgt atttccctaa accccagggc
     4561 cttgcgtgtg ctaatgggct ctattactga gcctgaccac tgagctacat tctcaactgt
     4621 aggttttttt aagaaggtct caggtcaatc tcgcagccta ggctggcttc agacttagaa
     4681 ttctgccctc ctcatctagc tcagatatgc actttaccct gtgttgcccc aaaacaattt
     4741 ttttacataa tcatagtttg tttccagact gagaaattac actagacacc atactgaata
     4801 aactttccct cgccgtgggt tgttatttgg tgggataagg ctgtgctgaa gttgaaccca
     4861 gggacctcac atgaagtgct acgtccatcc atgaggtgtt atgtgcagtc attgaatcgc
     4921 atgttttgtg tatagatacg tgaaattata ttacatggct tccacttacc taagacacgc
     4981 cctccctcca tccctaccct gacagcccat ggtcttttta ccaattttta tttagcattc
     5041 taccttttga aatgtacttt cttactccaa ataatatcct gagatctatc caagtgttga
     5101 gtgtgtcagt aattaattct tttcttattc tttactacca ctccctccaa gttgtttcaa
     5161 attgttgttt ccaaagaaaa aaggaaaaaa aagtcctcat tcacgtgaaa gatgtaggtg
     5221 tctgctgaat gtggttgccc tgtattaaag cttgtctcaa ctgaaagaaa cc
//
