LOCUS       NM_001107846            3479 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus STEAP2 metalloreductase (Steap2), mRNA.
ACCESSION   NM_001107846 XM_001067660 XM_231400
VERSION     NM_001107846.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3479)
  AUTHORS   Tokuda,E., Okawa,E. and Ono,S.
  TITLE     Dysregulation of intracellular copper trafficking pathway in a
            mouse model of mutant copper/zinc superoxide dismutase-linked
            familial amyotrophic lateral sclerosis
  JOURNAL   J Neurochem 111 (1), 181-191 (2009)
   PUBMED   19656261
REFERENCE   2  (bases 1 to 3479)
  AUTHORS   Ohgami,R.S., Campagna,D.R., McDonald,A. and Fleming,M.D.
  TITLE     The Steap proteins are metalloreductases
  JOURNAL   Blood 108 (4), 1388-1394 (2006)
   PUBMED   16609065
REFERENCE   3  (bases 1 to 3479)
  AUTHORS   Korkmaz,K.S., Elbi,C., Korkmaz,C.G., Loda,M., Hager,G.L. and
            Saatcioglu,F.
  TITLE     Molecular cloning and characterization of STAMP1, a highly
            prostate-specific six transmembrane protein that is overexpressed
            in prostate cancer
  JOURNAL   J Biol Chem 277 (39), 36689-36696 (2002)
   PUBMED   12095985
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474013.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_231400.4, XM_001067660.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3479
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q13"
     gene            1..3479
                     /gene="Steap2"
                     /note="STEAP2 metalloreductase"
                     /db_xref="GeneID:312052"
                     /db_xref="RGD:1307050"
     exon            1..158
                     /gene="Steap2"
                     /inference="alignment:Splign:2.1.0"
     exon            159..283
                     /gene="Steap2"
                     /inference="alignment:Splign:2.1.0"
     exon            284..805
                     /gene="Steap2"
                     /inference="alignment:Splign:2.1.0"
     CDS             317..1786
                     /gene="Steap2"
                     /note="six transmembrane epithelial antigen of prostate 2;
                     six transmembrane epithelial antigen of the prostate 2;
                     STEAP family member 2, metalloreductase"
                     /codon_start=1
                     /product="metalloreductase STEAP2"
                     /protein_id="NP_001101316.1"
                     /db_xref="GeneID:312052"
                     /db_xref="RGD:1307050"
                     /translation="MESISMMGSPKTLETFLPNGINGIKDARKVTVGVIGSGDFAKSL
                     TIRLIRCGYHVVIGSRNPKFASEFFPHVVDVTHHEDALTKTNIIFVAIHREHYTSLWD
                     LRHLLVGKVLIDVSNNMRVNQYPESNAEYLASLFPDSLIVKGFNVISAWALQLGPKDA
                     SRQVYICSNNIQARQQVIELARQLNFIPVDLGSLSSAKEIENLPLRLFTLWRGPVVVA
                     ISLATFFFIYSFVRDVIHPYARNQQSDFYKIPIEIVNKTLPIVAITLLSLVYLAGLLA
                     AAYQLYYGTKYRRFPPWLDTWLQCRKQLGLLSFFFAVVHVAYSLCLPMRRSERYLFLN
                     MAYQQVHANIENAWNEEEVWRIEMYISFGIMSLGLLSLLAVTSIPSVSNALNWREFSF
                     IQSTLGYVALLITTFHVLIYGWKRAFAEEYYRFYTPPNFVLALVLPSIVLLGKMMLLL
                     PCIGRKLKRIKKGWEKSQFLEEGMGGTVPHLSPERVTVM"
     exon            806..1333
                     /gene="Steap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1498
                     /gene="Steap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..3479
                     /gene="Steap2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagtcctt ggtccgggcc cagcagaaaa gaggccagga gaaaccttgt cccaggtagg
       61 atgtgcccga aagggaaagg acctgcaggt tacttttgcc aaccactttg gattgatgcg
      121 gcacttttca ctgtcataca gcgctgcttg gcaaacaggc cctcctcact acacgtaggc
      181 agttccagag tccagcagcg tctgccgcgt tcttttagaa atgcagcctc gggagcctcc
      241 ctccagctcc tctgagtgag aagctacacc ttaagattcc cagggcattc ctggtgatct
      301 tagaagagtc tctaccatgg aatccatctc tatgatggga agccctaaga ccctggagac
      361 gtttttgcct aatggcataa acggtatcaa agacgcaagg aaggtcaccg tgggggtgat
      421 aggaagtggg gattttgcca agtctctgac cattcggctt atcaggtgcg gctatcacgt
      481 ggtcatcgga agcagaaatc ctaagttcgc gtctgagttt tttcctcatg tggtagacgt
      541 cacccaccat gaagacgctt taacgaagac aaatataata ttcgtggcta tccatagaga
      601 acattacaca tccctgtggg acctgaggca tctgctggtg ggcaaagtcc tcattgatgt
      661 aagcaacaac atgagagtaa accagtaccc agaatccaat gcagagtacc tggcttcgtt
      721 atttccggat tccctgattg tcaaggggtt taatgtgatc tcagcctggg cacttcagtt
      781 aggtcccaag gatgccagcc gccaggttta tatatgcagc aacaatatcc aagctcgaca
      841 acaggttatt gagctcgccc gtcagttgaa ttttattccc gtcgacttgg gatctttgtc
      901 gtcagccaag gagattgaaa atttacccct gcgactgttc actctctgga gggggccagt
      961 ggtagtagcc ataagtttgg ccacgttttt ctttatttat tcctttgtca gggatgtgat
     1021 ccatccctat gccagaaacc agcagagtga cttttacaag attcctattg agattgtgaa
     1081 caaaacgttg cctatagtcg ctatcactct gctgtccctg gtatacctgg caggcctcct
     1141 ggcagctgcc tatcagcttt attacggaac gaagtaccgt aggtttccgc cgtggttgga
     1201 cacctggtta cagtgcagga aacagctggg gttgttgagc tttttctttg ccgtggtcca
     1261 cgttgcctac agcctctgct taccaatgag gaggtcggaa agatacttgt ttctcaacat
     1321 ggcttatcag caggttcatg cgaatattga aaatgcttgg aatgaggaag aggtttggag
     1381 gatcgagatg tacatctcct tcggcatcat gagcctgggc ttactgtccc tgctggcagt
     1441 cacttccatc ccttcagtga gcaacgcctt aaactggagg gagttcagtt ttattcagtc
     1501 tacgcttggc tacgtcgccc tgctcatcac aaccttccac gtgttaattt acggatggaa
     1561 acgcgcgttt gcggaagagt actaccgctt ttacacgccg ccaaactttg ttcttgcgct
     1621 tgtcttgccc tccattgtac ttctgggtaa gatgatgtta ctcctcccgt gcataggccg
     1681 aaagctcaaa cggattaaaa agggctggga aaagagccag tttctagagg agggcatggg
     1741 aggaactgtt cctcatctgt cccctgagag ggtcacagtg atgtgatgac aagaggtcct
     1801 cgctgatgcc gcacacactt ccattcatgc cattacttta ggccctcgcc ctgtccctgt
     1861 cagcggactg tcagttggcc acagtctgaa acctgcagtg agatttcagg agagagggac
     1921 atcagattct cttcaagtta atttttataa atgccatgtt tttccaacac gtaattttgt
     1981 agtccatata tattgttaca atctcagagt attttctttt gtgaaactgt aacagcattg
     2041 ttcttttaac cgtattgcgt agttgggcag aaatatttgt agctagtaac acagatgaag
     2101 tacgacgttt agaacatttg gcaaagcagc agaaatagaa gcttttaaca ttattcagtg
     2161 gatatgcttt ttccctgagg ctgaagattt taattattat ccaatttaag aagcagaaat
     2221 gcataatcat atttttttga gacggggcac atcacattag catctagggt acgagggaac
     2281 atcttaacgc tttcacaaaa acggggccgg aagaatgcca ttcattatac caagcagcat
     2341 gaacatgtga gcacgagtta aagacaagcc taaaattgta tttaatgtgc actggagaca
     2401 caaagtgaac actgccagtg cacaactcac gagagcttta gtctctgtca cattacagag
     2461 ccttccattt tcctctttgt caaccagggg aaggacccag cgtcacttga cctcccgaac
     2521 tgttactctg aatacagggc caaccccagg gattgtggac ctgcccttaa ttgtaatgaa
     2581 agtaattgtt acacaccagt gtgtgtttgt tactttggtc agtcaccacc tttcctgtgt
     2641 gggattttac cgacgtccac agagggagtg tggaatggtt ctaaacactg gtccatttaa
     2701 tacttacagc aaacccatgg aatggttctc tccatttccc acgtggaaaa ctgaagggta
     2761 gaaaagttaa gcttgcctga ggtcacacag tgagaaagtg gcaggtgagc agtcacctag
     2821 ggagtcctcc tcctggagcc acggctttat aagcatcagt atccacaacc cctgcccatg
     2881 cactaaggtc acaaggccgg tctcgatggc tccttccttg tacagtcatc ggcagccttc
     2941 agagtatgtt gaatgcttca aaggatgtct aaaggtatct taatcataat tttattattg
     3001 ctcgtggcag ggcatagttg cctggaaacc cagagtagcc caaagcctcc ccgtgcagtg
     3061 aaggactgag cagtcagaag gtggtaacta ttgatatcct gcgactcttt aaaaatcccc
     3121 acccacgtcc tctgctcctc ctgagaagcc ttcccgcctt tactaccatt catttggaag
     3181 cggtttttaa acataaagga tattaggaca catggttaat tataaatcta tatgattatg
     3241 tatctctgaa cacaaaatcg tatagacttc ccagtgctgg tcttccacga gtaaactgca
     3301 ttttgtccaa agtttgggat atacaacatg ttctccattt gttccttatt tattgtagta
     3361 aaacttacag acaagatgta attgtgtgtg ttcttcctaa aattgtatcg cctctaaagt
     3421 tgcccacaga cttgaatcga accatcaaaa ataaaaggac tcttattttt gtggaacct
//
