LOCUS       NM_013029               1422 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus ST8 alpha-N-acetyl-neuraminide
            alpha-2,8-sialyltransferase 3 (St8sia3), mRNA.
ACCESSION   NM_013029
VERSION     NM_013029.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Volkers,G., Worrall,L.J., Kwan,D.H., Yu,C.C., Baumann,L.,
            Lameignere,E., Wasney,G.A., Scott,N.E., Wakarchuk,W., Foster,L.J.,
            Withers,S.G. and Strynadka,N.C.
  TITLE     Structure of human ST8SiaIII sialyltransferase provides insight
            into cell-surface polysialylation
  JOURNAL   Nat Struct Mol Biol 22 (8), 627-635 (2015)
   PUBMED   26192331
REFERENCE   2  (bases 1 to 1422)
  AUTHORS   Angata,K., Suzuki,M., McAuliffe,J., Ding,Y., Hindsgaul,O. and
            Fukuda,M.
  TITLE     Differential biosynthesis of polysialic acid on neural cell
            adhesion molecule (NCAM) and oligosaccharide acceptors by three
            distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II
            (STX), and ST8Sia III
  JOURNAL   J Biol Chem 275 (24), 18594-18601 (2000)
   PUBMED   10766765
REFERENCE   3  (bases 1 to 1422)
  AUTHORS   Lee,Y.C., Kim,Y.J., Lee,K.Y., Kim,K.S., Kim,B.U., Kim,H.N.,
            Kim,C.H. and Do,S.I.
  TITLE     Cloning and expression of cDNA for a human Sia alpha 2,3Gal beta 1,
            4GlcNA:alpha 2,8-sialyltransferase (hST8Sia III)
  JOURNAL   Arch Biochem Biophys 360 (1), 41-46 (1998)
   PUBMED   9826427
REFERENCE   4  (bases 1 to 1422)
  AUTHORS   Zeng,G., Gao,L. and Yu,R.K.
  TITLE     Cloning of the cDNA coding for rat brain CMP-NeuAc:GD3 alpha2-8
            sialyltransferase
  JOURNAL   Gene 187 (1), 131-134 (1997)
   PUBMED   9073076
REFERENCE   5  (bases 1 to 1422)
  AUTHORS   Yoshida,Y., Kojima,N., Kurosawa,N., Hamamoto,T. and Tsuji,S.
  TITLE     Molecular cloning of Sia alpha 2,3Gal beta 1,4GlcNAc alpha
            2,8-sialyltransferase from mouse brain
  JOURNAL   J Biol Chem 270 (24), 14628-14633 (1995)
   PUBMED   7782326
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Nov 26, 2020 this sequence version replaced NM_013029.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U55938.1, SRR26643298.74401.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               JAXUCZ010000018.1  60024555-60024783
            230-352             JAXUCZ010000018.1  60026061-60026183
            353-910             JAXUCZ010000018.1  60028377-60028934
            911-1422            JAXUCZ010000018.1  60030539-60031050
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..1422
                     /gene="St8sia3"
                     /gene_synonym="Siat8c"
                     /note="ST8 alpha-N-acetyl-neuraminide
                     alpha-2,8-sialyltransferase 3"
                     /db_xref="GeneID:25547"
                     /db_xref="RGD:3680"
     exon            1..229
                     /gene="St8sia3"
                     /gene_synonym="Siat8c"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..1193
                     /gene="St8sia3"
                     /gene_synonym="Siat8c"
                     /note="Sialyltransferase 8 (GT3 alpha
                     2,8-sialyltransferase) C; sialyltransferase 8 C;
                     GT3-synthase; Sialyltransferase 8 (GT3 alpha
                     28-sialyltransferase) C; ST8 alpha-N-acetylneuraminate
                     alpha-2,8-sialyltransferase 3"
                     /codon_start=1
                     /product="sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha
                     2,8-sialyltransferase"
                     /protein_id="NP_037161.2"
                     /db_xref="GeneID:25547"
                     /db_xref="RGD:3680"
                     /translation="MRNCKMARVASILGLVMLSVALLILSLISYVSLKKENIFTTPKY
                     ASPGAPRMYMFHAGFRSQFALKFLDPSFVPITNSLTHELQEKPSKWTFNRTAFLHQRQ
                     EILQHVDVIKNFSLTKNSVRIGQLIHYDYSSHKYVFSISNNFRSLLPDVSPILNKRYN
                     ICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFHKDVGKKTNLTTFNPSILEKY
                     YNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLA
                     WPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDL
                     PYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA"
     exon            230..352
                     /gene="St8sia3"
                     /gene_synonym="Siat8c"
                     /inference="alignment:Splign:2.1.0"
     exon            353..910
                     /gene="St8sia3"
                     /gene_synonym="Siat8c"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1422
                     /gene="St8sia3"
                     /gene_synonym="Siat8c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgctcaatgg accgatttcc ccggtttccc tgaacccagc ctagcccgga atgagaaatt
       61 gcaaaatggc ccgagtcgcc agtatactag ggctggtcat gctcagcgtg gccctgctga
      121 ttttatcgct tatcagctac gtgtccctga aaaaggagaa catcttcacc actcccaagt
      181 acgccagccc gggggcgccc cgaatgtaca tgttccacgc gggattccgg tcacagtttg
      241 cactgaagtt tctagacccg tcatttgtgc ccattacgaa ttctctcacc catgaactcc
      301 aagagaaacc ttctaaatgg acatttaatc ggacagcgtt tttacatcaa aggcaagaaa
      361 ttcttcagca tgtcgatgta ataaaaaatt tttctttaac caagaatagt gttcggatcg
      421 gacaactgat acattacgat tattccagcc ataaatatgt tttctctatt agcaataact
      481 tccggtccct gctcccagat gtgtcgccca ttctgaataa gcgttataac atttgtgctg
      541 tggtcggaaa cagtggaatc ttgacaggga gtcagtgtgg acaagaaata gataaatcgg
      601 attttgtttt tcggtgcaat tttgccccga cagaggcttt ccacaaagat gttgggaaga
      661 aaaccaacct cacaactttc aatcctagca tcttggaaaa atattacaac aaccttttaa
      721 ccatccagga ccgtaacaac ttcttcctca gtttaaaaaa gctcgacggg gccattctct
      781 ggatccccgc atttttcttc cacacttctg cgactgtaac cagaacctta gtggattttt
      841 tcgttgagca cagaggtcag ttaaaggtcc agttggcttg gcctggaaat atcatgcaac
      901 atgtcaacag gtactggaaa aacaaacact tgtcacccaa acgactgagc acaggtatcc
      961 ttatgtacac ccttgcatct gcaatatgtg aagagatcca cttgtacggt ttctggcctt
     1021 tcggatttga ccccaacacc agggaggatc tgccctacca ctactatgac aaaaaaggaa
     1081 ccaaatttac caccaagtgg caggagtctc accagctgcc tgctgagttt cagctgctct
     1141 atcgaatgca tggggaaggg ctcacaaagc tcactctgtc acactgtgcc taagaactcc
     1201 aaatggaaag tgccaatggc tgtttaaaaa gtgcccccaa accaaattga atagtctcca
     1261 gaacagaacc catagacaat ctggcaaagc ctgtctgcca cttacaagga aagatatctt
     1321 ctcttcctct tttgcactgc tctttgaatg gtccgaacag acttaggaca ggtgcattga
     1381 agccgtgtct tttagacttg actgggaaag gttatattgc at
//
