LOCUS       NM_001271361            1904 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ST6 N-acetylgalactosaminide
            alpha-2,6-sialyltransferase 5 (St6galnac5), mRNA.
ACCESSION   NM_001271361 XM_001078153
VERSION     NM_001271361.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1904)
  AUTHORS   Harduin-Lepers,A., Mollicone,R., Delannoy,P. and Oriol,R.
  TITLE     The animal sialyltransferases and sialyltransferase-related genes:
            a phylogenetic approach
  JOURNAL   Glycobiology 15 (8), 805-817 (2005)
   PUBMED   15843597
  REMARK    Erratum:[Glycobiology. 2005 Sep;15(9):21G]
REFERENCE   2  (bases 1 to 1904)
  AUTHORS   Tsuchida,A., Okajima,T., Furukawa,K., Ando,T., Ishida,H.,
            Yoshida,A., Nakamura,Y., Kannagi,R., Kiso,M. and Furukawa,K.
  TITLE     Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer
            cell lines by a sialyltransferase, ST6GalNAc VI, responsible for
            the synthesis of alpha-series gangliosides
  JOURNAL   J Biol Chem 278 (25), 22787-22794 (2003)
   PUBMED   12668675
REFERENCE   3  (bases 1 to 1904)
  AUTHORS   Okajima,T., Fukumoto,S., Ito,H., Kiso,M., Hirabayashi,Y., Urano,T.
            and Furukawa,K.
  TITLE     Molecular cloning of brain-specific GD1alpha synthase (ST6GalNAc V)
            containing CAG/Glutamine repeats
  JOURNAL   J Biol Chem 274 (43), 30557-30562 (1999)
   PUBMED   10521438
  REMARK    Erratum:[J Biol Chem 2000 Jan 14;275(2):1520]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001271361.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ646872.1, SRR26643298.14101.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-245               JAXUCZ010000002.1  244570853-244571097 c
            246-500             JAXUCZ010000002.1  244569879-244570133 c
            501-910             JAXUCZ010000002.1  244429377-244429786 c
            911-1018            JAXUCZ010000002.1  244422801-244422908 c
            1019-1904           JAXUCZ010000002.1  244402589-244403474 c
FEATURES             Location/Qualifiers
     source          1..1904
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q45"
     gene            1..1904
                     /gene="St6galnac5"
                     /gene_synonym="Siat7E; ST6GalNAcV"
                     /note="ST6 N-acetylgalactosaminide
                     alpha-2,6-sialyltransferase 5"
                     /db_xref="GeneID:365984"
                     /db_xref="RGD:1564252"
     exon            1..245
                     /gene="St6galnac5"
                     /gene_synonym="Siat7E; ST6GalNAcV"
                     /inference="alignment:Splign:2.1.0"
     CDS             231..1250
                     /gene="St6galnac5"
                     /gene_synonym="Siat7E; ST6GalNAcV"
                     /note="alpha-N-acetylgalactosaminide
                     alpha-2,6-sialyltransferase V; GD1 alpha synthase; GalNAc
                     alpha-2,6-sialyltransferase V; sialyltransferase 7E; ST6
                     (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,
                     3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5;
                     ST6 GalNAc alpha-2,6-sialyltransferase 5"
                     /codon_start=1
                     /product="alpha-N-acetylgalactosaminide
                     alpha-2,6-sialyltransferase 5"
                     /protein_id="NP_001258290.1"
                     /db_xref="GeneID:365984"
                     /db_xref="RGD:1564252"
                     /translation="MKTLMRHGLAVCLVLTTMCTSLLLVYSSLGSQKERPPQQQQQQQ
                     QQQQQQQQQATATGSTQLVESSPQPHRTAPVGPRQLDGYLGVADHKPLKMHCKDCALV
                     TSSGHLLRSQQGPHIDQTECVIRMNDAPTRGYGLDVGNRTSLRVIAHSSIQRILRNRH
                     DLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLQLLSQVLPRLKAFMITRHKMLQFDEL
                     FKQETGKDRKISNTWLSTGWFTMTIALELCDRIDVYGMVPPDFCRDPKHPSVPYHYYE
                     PSGPDECTMYLSHERGRKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPEPPAVNPAE
                     DKPVF"
     exon            246..500
                     /gene="St6galnac5"
                     /gene_synonym="Siat7E; ST6GalNAcV"
                     /inference="alignment:Splign:2.1.0"
     exon            501..910
                     /gene="St6galnac5"
                     /gene_synonym="Siat7E; ST6GalNAcV"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1018
                     /gene="St6galnac5"
                     /gene_synonym="Siat7E; ST6GalNAcV"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1904
                     /gene="St6galnac5"
                     /gene_synonym="Siat7E; ST6GalNAcV"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgtgtgga tcgctgagac tcggagggtc cggctcagtt ttaattctcc tctaatctcc
       61 gcaacagcag cgcttcccgg gtcccgcggc tcctgctccc gctcagccgc cctcactgcc
      121 aggtgagcat ctgagcagcc tccgccccat cacccgccat ggacaacctc caagaaaaag
      181 tggctccgga cgcgcttgcc tgagaattcc gcacaaaaga ggagcccaaa atgaagaccc
      241 tgatgcgcca tggtctggca gtgtgtttag tgctcactac catgtgcacc agcttgttgc
      301 tcgtgtacag cagcctcggc agccagaagg agcggccccc gcagcagcag cagcagcagc
      361 agcagcagca gcagcagcag cagcagcagg cgactgcgac tggcagcacg cagcttgtgg
      421 agagcagtcc ccagccacat agaaccgccc ccgtaggacc ccggcagcta gacggatacc
      481 tcggtgtagc agaccacaag cccttgaaaa tgcattgcaa ggattgcgcc ctggtgacca
      541 gctcggggca cctgctgcgt agtcagcagg gcccccacat cgaccagaca gagtgtgtta
      601 tccgtatgaa tgacgccccc acccgaggct acgggcttga cgtgggcaac cgcacaagcc
      661 tgcgagtcat cgcacattcc agcatccaga ggatcctccg caaccgccat gacctgctca
      721 acgtgagcca gggcaccgtg ttcatcttct ggggccccag cagctacatg cggcgggatg
      781 gcaagggcca ggtgtacaat aacctgcagc tcctcagcca agtgctgccg cggctgaagg
      841 ccttcatgat cacgcgccac aagatgctgc agttcgatga gctcttcaag caggagactg
      901 gcaaagacag gaagatctcc aacacttggc tgagcactgg ctggttcacc atgacaattg
      961 ctctggagct ctgtgacagg atcgatgttt acggcatggt gcccccagac ttctgcaggg
     1021 acccaaagca cccttccgta ccctatcatt actatgagcc ttctggaccc gatgaatgta
     1081 caatgtacct ctctcacgaa cgaggacgca agggcagtca ccaccgtttc attacagaga
     1141 aacgggtatt taagaactgg gcacggacct tcaacattca ctttttccaa ccagactgga
     1201 aaccagaacc acccgctgtg aatcctgctg aggataagcc tgtgttctga ggggtgaacg
     1261 tgatggatag catccctgct gtctggcaga agaacttgac ctctggcagg gaaatgggaa
     1321 ctgaatgggt ggctgagaag agcggcgtcc ttcagcaccg tggacagaac ccggcggcca
     1381 gcgaacattc cggaatgcat acattctaat cagtattgtc tcttggaaag agcaactgta
     1441 gccactgcca tagctaggaa cacttccagg tctctgaagt attgccttca aatctgaaac
     1501 aggagcagcc caactcttag ttgcgtttct ttacagacat ccacgtcaaa ggatttttct
     1561 atcaggctgt aacctaacct gacctgtaat ctttgccatt tgtcagacaa atttgtgatt
     1621 tgtaaaaggc ctgaaagtgt ggacgtgttt ctgaagagca catctccaat gattttcata
     1681 aagcaaatgt ctgctattta tttattgaga gttttttagt gtactctagg cagtattttt
     1741 atagattatg attatgtggc aatttattcc tcctgactgt ttaatcctga tcggtggtcg
     1801 gaatgggcta ggattgggct gatgagttac tgaattcaca aggctcgtta ttagcttgaa
     1861 atcggtattt gacgtggaag tgtgcacgtg agagttgaac ctct
//
