LOCUS       NM_001031652            1997 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ST6 N-acetylgalactosaminide
            alpha-2,6-sialyltransferase 2 (St6galnac2), mRNA.
ACCESSION   NM_001031652 XM_221134
VERSION     NM_001031652.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1997)
  AUTHORS   Moremen,K.W., Ramiah,A., Stuart,M., Steel,J., Meng,L., Forouhar,F.,
            Moniz,H.A., Gahlay,G., Gao,Z., Chapla,D., Wang,S., Yang,J.Y.,
            Prabhakar,P.K., Johnson,R., Rosa,M.D., Geisler,C., Nairn,A.V.,
            Seetharaman,J., Wu,S.C., Tong,L., Gilbert,H.J., LaBaer,J. and
            Jarvis,D.L.
  TITLE     Expression system for structural and functional studies of human
            glycosylation enzymes
  JOURNAL   Nat Chem Biol 14 (2), 156-162 (2018)
   PUBMED   29251719
REFERENCE   2  (bases 1 to 1997)
  AUTHORS   Harduin-Lepers,A., Mollicone,R., Delannoy,P. and Oriol,R.
  TITLE     The animal sialyltransferases and sialyltransferase-related genes:
            a phylogenetic approach
  JOURNAL   Glycobiology 15 (8), 805-817 (2005)
   PUBMED   15843597
  REMARK    Erratum:[Glycobiology. 2005 Sep;15(9):21G]
REFERENCE   3  (bases 1 to 1997)
  AUTHORS   Samyn-Petit,B., Krzewinski-Recchi,M.A., Steelant,W.F., Delannoy,P.
            and Harduin-Lepers,A.
  TITLE     Molecular cloning and functional expression of human ST6GalNAc II.
            Molecular expression in various human cultured cells
  JOURNAL   Biochim Biophys Acta 1474 (2), 201-211 (2000)
   PUBMED   10742600
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001031652.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099812.1, AJ634457.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               JAXUCZ010000010.1  102426610-102426761 c
            153-213             JAXUCZ010000010.1  102422790-102422850 c
            214-388             JAXUCZ010000010.1  102418684-102418858 c
            389-557             JAXUCZ010000010.1  102417964-102418132 c
            558-696             JAXUCZ010000010.1  102417236-102417374 c
            697-800             JAXUCZ010000010.1  102414650-102414753 c
            801-884             JAXUCZ010000010.1  102412737-102412820 c
            885-984             JAXUCZ010000010.1  102410797-102410896 c
            985-1997            JAXUCZ010000010.1  102409048-102410060 c
FEATURES             Location/Qualifiers
     source          1..1997
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.2"
     gene            1..1997
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /note="ST6 N-acetylgalactosaminide
                     alpha-2,6-sialyltransferase 2"
                     /db_xref="GeneID:303692"
                     /db_xref="RGD:1560747"
     exon            1..152
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..1152
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /EC_number="2.4.3.7"
                     /note="sialyltransferase 7B; Gal-beta-1,3-GalNAc
                     alpha-2,6-sialyltransferase; ST6GalNAc II; ST6
                     (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,
                     3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2;
                     ST6GALNAC2, alpha-2,6-sialyltransferase 2; ST6 GalNAc
                     alpha-2,6-sialyltransferase 2;
                     alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
                     II ()"
                     /codon_start=1
                     /product="alpha-N-acetylgalactosaminide
                     alpha-2,6-sialyltransferase 2"
                     /protein_id="NP_001026822.1"
                     /db_xref="GeneID:303692"
                     /db_xref="RGD:1560747"
                     /translation="MDLPRRWLFRMLLLVATSSGILFMLYSSAGQGSPETQVPARSTT
                     SPRAFFEPKAPNSENRKSPSCQHSLSLAIQKDHRFRGLFDLSTPVLLWDGLFTQELWN
                     NLSQHKVPYGWQGLSRKVIASTLTLLKDPESAELFGASGKLPLSCISCAVVGNGGILN
                     GSRQGQKIDAHDYVFRINGAITKGFELDVGTKTSFYGFTVNTMKNSLISYSKLGFTSV
                     PQGQDLRYIFIPSSIRDYLMLRSAILGVPVPEGPDKGDRPHIYFGPETSASKFKLLHP
                     DFIGYLTERFLKSKLINTRFGDMYMPSTGALILLTALHACDQVSAYGFITNNYQKYSD
                     HYFEREKKPLIFYANHDLSLEAALWRDLHNAGILWLYQR"
     exon            153..213
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
     exon            214..388
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
     exon            389..557
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
     exon            558..696
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
     exon            697..800
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
     exon            801..884
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
     exon            885..984
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1997
                     /gene="St6galnac2"
                     /gene_synonym="Siat7b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagacgggg cgcaccccgg ccaggctcgc atggacctcc cgcgccgctg gctctttcga
       61 atgttgctgc tcgtcgccac cagctccggg attctcttca tgctgtactc ctcggcgggg
      121 caggggtccc cggagaccca ggttcccgcc aggagcacca cgtcgcctag agcattcttt
      181 gagcccaagg caccgaattc ggaaaacaga aagagcccat cctgccaaca ctcgctatcc
      241 ctggccattc agaaggacca tcgcttccgg ggcctgtttg acctctccac cccagtgctt
      301 ctgtgggacg gcctcttcac ccaagagctg tggaataatc tgagtcagca caaagtcccc
      361 tacggatggc aggggctctc ccggaaagtc attgcctcta ccctgacact tctgaaggac
      421 ccagagagcg cagagctgtt tggtgcctcc gggaaactac ccctgagctg tatcagctgt
      481 gccgtggtgg gtaatggagg aattctgaat gggtcccggc agggtcagaa aatcgatgcg
      541 cacgactatg tcttcagaat caatggcgcc ataaccaaag gctttgagct cgacgtgggc
      601 actaagacct ccttctacgg tttcaccgtg aacaccatga agaactcgct catctcctac
      661 tccaaactgg gcttcacctc tgtgccgcaa gggcaggacc tgcgctacat cttcatcccc
      721 tcaagcatcc gggattacct gatgctgaga tctgccattc taggtgtgcc tgttccagaa
      781 ggaccagata aaggggacag gcctcacatc tatttcggac cggaaacctc tgccagtaaa
      841 ttcaagctcc tgcatccgga cttcatcggc tacctgacag aaaggtttct gaaatccaag
      901 ttgatcaaca cacgttttgg agacatgtac atgcctagca caggagcgct catattgctg
      961 acagccctgc acgcctgtga ccaggttagt gcctacggat tcatcactaa caactaccag
     1021 aagtactcag accactattt cgaacgagag aagaaaccac tgatattcta cgcaaaccat
     1081 gatctgtccc tggaagctgc gctatggcga gatctgcaca acgccggcat cctctggctg
     1141 taccaacgct gaccccaaag tgtccgatgt ctgtgcttca aaagcacttt tcctgacctt
     1201 tcaacctttg gaagaagcaa gactcccctt ggccctccgc ttcccaacag agggtattga
     1261 gacaagaccc atcccaatac cagagcctgt tcaatgcacg acaccgtcac gcgacaagac
     1321 agctcttccg agtcttagcc aagggaaggc agactgcttt gtaggatctg ttgtaaacgg
     1381 aacatactct ccccatatga gacagtgacc ctcaccagca aagaggcagg cacatttcag
     1441 agctaagtag ttcaaagcca gcacctggtc tggagcgact agaaacatta atggaacccc
     1501 tcagtggtat ccagtgacca gtggagcaga cacccgcccc agctgaaacc aatggcaggt
     1561 tgcgtcccaa atgccaaagc cattcaacct aggacacatt acgagtttct aagaacatga
     1621 ccctcctgcc ccccccccca acctccgaga gaggatgaga accagaggca gaatgtagtt
     1681 tgagggtaga taatagggta agtgatggat gaccattttg tcttttgtgt gtgttggtag
     1741 agtagaagac acaaactgca aggtggtatg tctggtggga agggctgtgg tggcactcag
     1801 gacagacttg gtggctcatg caccaagacc caaggctatg ggcacctagc accacagctg
     1861 ggaggttgtg gcatctgacc accttgcgca taagtcgtca ccgctgagag ctgctggagt
     1921 ggaccttgtc accaacagga aactagtgac aggccctcac ctcacagctt caataaacag
     1981 cacctgatac agtccaa
//
