LOCUS       NM_001100888            1800 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus ST6 beta-galactoside alpha-2,6-sialyltransferase
            2 (St6gal2), mRNA.
ACCESSION   NM_001100888 XM_001058146 XM_236826
VERSION     NM_001100888.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1800)
  AUTHORS   Harduin-Lepers,A., Mollicone,R., Delannoy,P. and Oriol,R.
  TITLE     The animal sialyltransferases and sialyltransferase-related genes:
            a phylogenetic approach
  JOURNAL   Glycobiology 15 (8), 805-817 (2005)
   PUBMED   15843597
  REMARK    Erratum:[Glycobiology. 2005 Sep;15(9):21G]
REFERENCE   2  (bases 1 to 1800)
  AUTHORS   Takashima,S., Tsuji,S. and Tsujimoto,M.
  TITLE     Comparison of the enzymatic properties of mouse beta-galactoside
            alpha2,6-sialyltransferases, ST6Gal I and II
  JOURNAL   J Biochem 134 (2), 287-296 (2003)
   PUBMED   12966079
REFERENCE   3  (bases 1 to 1800)
  AUTHORS   Takashima,S., Tsuji,S. and Tsujimoto,M.
  TITLE     Characterization of the second type of human beta-galactoside alpha
            2,6-sialyltransferase (ST6Gal II), which sialylates Galbeta
            1,4GlcNAc structures on oligosaccharides preferentially. Genomic
            analysis of human sialyltransferase genes
  JOURNAL   J Biol Chem 277 (48), 45719-45728 (2002)
   PUBMED   12235148
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On or before Feb 16, 2013 this sequence version replaced
            XM_236826.4, XM_001058146.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB605923.1, SRR26360194.2300751.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN12840105
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                JAXUCZ010000009.1  9509582-9509613
            33-179              JAXUCZ010000009.1  9513390-9513536
            180-1153            JAXUCZ010000009.1  9542835-9543808
            1154-1251           JAXUCZ010000009.1  9563464-9563561
            1252-1353           JAXUCZ010000009.1  9567410-9567511
            1354-1528           JAXUCZ010000009.1  9569704-9569878
            1529-1800           JAXUCZ010000009.1  9593679-9593950
FEATURES             Location/Qualifiers
     source          1..1800
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..1800
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /note="ST6 beta-galactoside alpha-2,6-sialyltransferase 2"
                     /db_xref="GeneID:301155"
                     /db_xref="RGD:1559663"
     exon            1..32
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /inference="alignment:Splign:2.1.0"
     exon            33..179
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /inference="alignment:Splign:2.1.0"
     exon            180..1153
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /inference="alignment:Splign:2.1.0"
     CDS             223..1800
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /EC_number="2.4.3.1"
                     /note="ST6Gal II; alpha 2,6-ST 2;
                     CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,
                     6-sialyltransferase 2; ST6 beta-galactosamide
                     alpha-2,6-sialyltranferase 2"
                     /codon_start=1
                     /product="beta-galactoside alpha-2,6-sialyltransferase 2"
                     /protein_id="NP_001094358.1"
                     /db_xref="GeneID:301155"
                     /db_xref="RGD:1559663"
                     /translation="MKPHLKQWRQRMLFAIFVWGLLFLAIFIYFTNSNPAAPMPSSFS
                     FLESRGLLPVQGKQRVIMGALQEPSLPRSLEPSKVLMDGHSASPFNSWPGDPQKGDQA
                     QDGFDNGDEFFTSQVGRKSQSAFYPEEDNYFFVAGQPGLYHHRQGALGLPSPGESSWQ
                     SGPGQPKQEKLRHPRRGSLPEEAYDSDMLSTSMSRAFLYRLWKGTVSSKMLNPRLQKA
                     MRYYMSFNKHGVRFSRRGRREARRTGPELLCEMRKRVRVRTLDGKEAPFSGLGWRPLV
                     PGVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNK
                     TTVRIINSQILANPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQ
                     HRLKYPTQPFYILHPKFIWQLWDIIQENTREKIQPNPPSSGFIGILVMMSMCQEVHVY
                     EYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRLNTGTQADLHHKGKVVLP
                     GFQTLRCPVTRPNNTNT"
     exon            1154..1251
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1353
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1528
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1800
                     /gene="St6gal2"
                     /gene_synonym="ST6Gal-II; ST6GalII"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggccgatcaa ctctccagtg cctagcggct agtgagaaga ctgggcctca gaaaagtgaa
       61 atgtcttgac agagctggca gatttgccca aaccttatgc ttctaggctg tgctctgtgc
      121 tacggacgaa cacgaatgac cattgtcaaa attgtgtcca gccagagatt gctgcaactg
      181 ttttgagacc ccaaggtgaa gtgctggccc caaagatctg caatgaaacc acacttgaag
      241 caatggcgac aacgaatgct ctttgcaata tttgtttggg ggctcctctt tttggcaatt
      301 ttcatctatt tcaccaacag caatcctgct gcacctatgc ccagctcctt ttccttcctg
      361 gagagccgcg ggctcctgcc tgtgcagggc aagcagaggg tcatcatggg tgcattgcag
      421 gagccctctt tgcccagaag tttggagcca agcaaagtac tgatggacgg ccactctgcg
      481 agccctttca acagctggcc tggggaccca cagaaagggg accaggccca agatggcttt
      541 gacaatgggg atgagttttt tacatcccag gtcgggagga aatcacaaag tgctttctat
      601 cctgaggaag acaactactt ttttgttgcg ggtcagcctg ggttgtacca ccaccggcag
      661 ggtgccctgg ggctgccatc tccgggggag tcctcatggc aatcaggacc tggtcagccc
      721 aagcaggaga agctgcgtca cccaaggaga ggcagtttgc ctgaggaagc ctatgatagt
      781 gacatgctgt cgacctccat gtccagagcc ttcctgtacc ggctctggaa gggaaccgtg
      841 tcctctaaga tgttgaaccc gcgcctgcag aaagccatgc gctactacat gtcctttaac
      901 aagcacggtg tgcgcttcag caggcggggg cggcgtgagg cacgacgtac agggccagag
      961 ctgctgtgcg agatgcgcaa gcgtgtgcgt gtgcgcacct tggacggcaa agaggcgccc
     1021 ttctcagggc tgggctggcg gcctctggta cctggggtcc ctctgagcca gttgcacccc
     1081 cgcggtttgc gcagctgcgc agttgtaatg tctgccggag ccatcctgaa ctcctccttg
     1141 ggggaggaaa tcgattctca tgatgcagtt ttgagattta actctgcccc tacacgtggc
     1201 tatgagaaag atgtcggaaa taaaaccaca gtacgcatca ttaattctca gattctggcc
     1261 aaccccagcc atcacttcat tgacagttct ttatataaag atgttattct ggtagcctgg
     1321 gatccagctc cttattctgc caatcttaac ctgtggtata agaagccaga ttacaacctt
     1381 ttcactccat atatccagca tcgcctgaaa tacccaactc agccatttta cattcttcac
     1441 cccaaattca tatggcagct ttgggacatt atccaggaaa acacaaggga gaagatacag
     1501 cccaacccac catcttctgg ttttattgga atcctcgtca tgatgtccat gtgccaagag
     1561 gtgcacgtgt atgagtacat cccatctgtc agacagacag aactttgcca ctaccatgag
     1621 ctgtactacg acgcagcctg caccttggga gcctaccacc cattgcttta tgaaaagcta
     1681 ctggtgcagc gccttaacac aggcacccag gcagatttgc accacaaggg aaaggtggtc
     1741 ctgccaggct tccagactct gcggtgccca gtaaccaggc ccaacaatac aaacacttaa
//
