LOCUS       NM_207602               2158 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ST3 beta-galactoside alpha-2,3-sialyltransferase
            6 (St3gal6), mRNA.
ACCESSION   NM_207602 XM_221543
VERSION     NM_207602.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2158)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   2  (bases 1 to 2158)
  AUTHORS   Groux-Degroote,S., Krzewinski-Recchi,M.A., Cazet,A., Vincent,A.,
            Lehoux,S., Lafitte,J.J., Van Seuningen,I. and Delannoy,P.
  TITLE     IL-6 and IL-8 increase the expression of glycosyltransferases and
            sulfotransferases involved in the biosynthesis of sialylated and/or
            sulfated Lewisx epitopes in the human bronchial mucosa
  JOURNAL   Biochem J 410 (1), 213-223 (2008)
   PUBMED   17944600
REFERENCE   3  (bases 1 to 2158)
  AUTHORS   Harduin-Lepers,A., Mollicone,R., Delannoy,P. and Oriol,R.
  TITLE     The animal sialyltransferases and sialyltransferase-related genes:
            a phylogenetic approach
  JOURNAL   Glycobiology 15 (8), 805-817 (2005)
   PUBMED   15843597
  REMARK    Erratum:[Glycobiology. 2005 Sep;15(9):21G]
REFERENCE   4  (bases 1 to 2158)
  AUTHORS   Okajima,T., Fukumoto,S., Miyazaki,H., Ishida,H., Kiso,M.,
            Furukawa,K., Urano,T. and Furukawa,K.
  TITLE     Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI)
            that sialylates type II lactosamine structures on glycoproteins and
            glycolipids
  JOURNAL   J Biol Chem 274 (17), 11479-11486 (1999)
   PUBMED   10206952
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC092560.1.
            
            [WARNING] On Oct 11, 2024 this sequence was replaced by
            NM_207602.3.
            
            On Apr 11, 2005 this sequence version replaced NM_207602.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092560.1, AJ626743.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2158
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q12"
     gene            1..2158
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /note="ST3 beta-galactoside alpha-2,3-sialyltransferase 6"
                     /db_xref="GeneID:304023"
                     /db_xref="RGD:1303279"
     exon            1..133
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     exon            134..315
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     CDS             227..1222
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /EC_number="2.4.99.-"
                     /note="ST3Gal VI; CMP-NeuAc:beta-galactoside
                     alpha-2,3-sialyltransferase VI; ST3GalVI;
                     sialyltransferase 10 (alpha-2,3-sialyltransferase VI)"
                     /codon_start=1
                     /product="type 2 lactosamine alpha-2,3-sialyltransferase"
                     /protein_id="NP_997485.2"
                     /db_xref="GeneID:304023"
                     /db_xref="RGD:1303279"
                     /translation="MKGYVVAIFLSSIFLYYVLYCILWGTNGYWFPNEEMKSKNNVKN
                     CFKKPAFASLLRFPQFYPFLCKADFVKVAATYGTNNFLLPYGVKTFESYFRSALSKLQ
                     SCDLFGEFDTVPCKRCVVVGNGGVLKNKTLGAKIDSYDVIIRMNNGPVLGHEEEVGKR
                     TTFRLFYPESVFSDPSHYDPNTTAVLVVFKPQDLRWLMEILIGKKINTDGFWKKPALK
                     LIYKQYQIRILDPYIIREAAFQLLRFPRVFPKDQKPKHPTTGIIALTLAFHICSEVHL
                     AGFKYNFYTPDSPLHYYGNATMSLMKKNAYHNLTAEQLFLKNLIKKKMVINLTQN"
     exon            316..393
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     exon            394..497
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     exon            498..561
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     exon            562..657
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     exon            658..844
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     exon            845..982
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1135
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..2112
                     /gene="St3gal6"
                     /gene_synonym="Siat10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttggattgt ttccagtatc cagacctcca catgtcagca gtagtctcct gaggcgttct
       61 accctccctc tactctcctc ctatcgatct tcagaaagaa agggtgttca ggaaacgcac
      121 cctaaaggca cagattcact tgctagttca tgtatttgag ccattgtgga agacctctgc
      181 ccattcacct cctctcgctt tggaccttgt ttctggcagg ccagccatga aaggctacgt
      241 ggtggccata ttcttgagct ccatcttcct ctactatgtg ctatactgta tcctgtgggg
      301 aacaaatggc tattggttcc caaatgagga aatgaagagt aaaaacaatg tcaagaactg
      361 ttttaaaaag ccagctttcg ccagtcttct gaggtttcct cagttttacc catttctgtg
      421 taaagctgac tttgtaaagg ttgccgccac atacggtacc aataattttc tgttgcccta
      481 tggagtaaag acctttgaat cgtatttcag atcggccctt tcaaaactgc agagctgtga
      541 tctctttggc gagtttgaca cagtgccatg taaaaggtgt gtggtggttg gtaatggagg
      601 agtgttgaag aataagacgt tgggagcaaa aatcgactcc tatgatgtaa taataagaat
      661 gaataacggt cctgttttag gccatgaaga ggaagttggg aaaaggacaa ccttcaggct
      721 tttctatcca gagtctgtct tttcagaccc cagtcactat gatcccaata ctaccgcggt
      781 tctcgttgtc tttaaaccac aggatttaag gtggctgatg gaaatactga taggtaaaaa
      841 aataaatact gatgggtttt ggaagaaacc ggccttaaaa ctgatctata aacaatacca
      901 aatcagaata ttagatccat atattatcag agaagcagct tttcaactgc ttcgttttcc
      961 cagagtattt cccaaagatc agaaacccaa gcaccccacg acgggaatta tcgctctcac
     1021 cttggcgttt cacatatgca gtgaagtgca ccttgctggt tttaagtaca acttttacac
     1081 accagacagt cctttacact actatgggaa tgccaccatg tctttgatga agaagaatgc
     1141 gtatcacaat ctgactgcag aacagctctt tctaaagaac cttataaaga aaaaaatggt
     1201 gatcaacttg actcaaaatt gaccgtatag actcaaaaga cgacgctaaa cagtattagt
     1261 tttatttttg tactgcaaat tttagtttat ttttaaatat attgaatgaa cttatcaaat
     1321 aattgtgtat attaggtctg ttgctgcctg gtgatttgta accatcagct acatttctgt
     1381 gaatatattt atgaaaaact aagattttta gttaagatat cagggaaata tgtaatgatc
     1441 atgttttgat catgttgttt ttaaatatga tctttagtgt tctgaggggt tttaaaatac
     1501 cttttcaaag tttcttcatc ttaagagttc taggcgattt aactgacttc acttattctg
     1561 acagtcacat atcattttga gatgcttatt aagattggtt actcccaggc atgtgacagg
     1621 aaccaggggc aggaaaccag aattgcctgg ttgtggaagt ccatggtatc catagcggtt
     1681 taattaagtt tcctctgcaa ttaattaaag cagtaataat ttcctgttag ggagtaaagg
     1741 tagccttgtc catgttagaa aagcactctc acacgatgca tcctgagact ttggtgtggg
     1801 gaagcaggtt cttactatgt agcccatgca ggccttgaac ttgtcttctt gcctcagctt
     1861 tccaagttct gggattacag ccatgtgcca ttgcacccta cagcatcgtt tcttaaaatt
     1921 aagaagtttt ttttttaaga cagggtctat atagctctgg atggcctaga aactccaatg
     1981 tagtctaggt tggatttgaa ctcagaggtg agcctttctg ttggatgaag ggtgtgtgtc
     2041 agtgttaact gttcaagaaa acttaaatgt ttatttgaag aaaattagaa cagtaaaaca
     2101 atgcaaataa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
