LOCUS       NM_001398712            2301 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus ST3 beta-galactoside alpha-2,3-sialyltransferase
            5 (St3gal5), transcript variant 1, mRNA.
ACCESSION   NM_001398712 XM_006236676
VERSION     NM_001398712.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2301)
  AUTHORS   Kono,M., Takashima,S., Liu,H., Inoue,M., Kojima,N., Lee,Y.C.,
            Hamamoto,T. and Tsuji,S.
  TITLE     Molecular cloning and functional expression of a fifth-type alpha
            2,3-sialyltransferase (mST3Gal V: GM3 synthase)
  JOURNAL   Biochem Biophys Res Commun 253 (1), 170-175 (1998)
   PUBMED   9875239
REFERENCE   2  (bases 1 to 2301)
  AUTHORS   Ishii,A., Ohta,M., Watanabe,Y., Matsuda,K., Ishiyama,K., Sakoe,K.,
            Nakamura,M., Inokuchi,J., Sanai,Y. and Saito,M.
  TITLE     Expression cloning and functional characterization of human cDNA
            for ganglioside GM3 synthase
  JOURNAL   J Biol Chem 273 (48), 31652-31655 (1998)
   PUBMED   9822625
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Dec 22, 2021 this sequence version replaced XM_006236676.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.16400.1,
                                           SRR26643298.23481.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               JAXUCZ010000004.1  105692840-105693011
            173-296             JAXUCZ010000004.1  105726768-105726891
            297-408             JAXUCZ010000004.1  105730795-105730906
            409-752             JAXUCZ010000004.1  105740093-105740436
            753-939             JAXUCZ010000004.1  105743991-105744177
            940-1098            JAXUCZ010000004.1  105745744-105745902
            1099-2301           JAXUCZ010000004.1  105749572-105750774
FEATURES             Location/Qualifiers
     source          1..2301
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q32"
     gene            1..2301
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /note="ST3 beta-galactoside alpha-2,3-sialyltransferase 5"
                     /db_xref="GeneID:83505"
                     /db_xref="RGD:620875"
     exon            1..172
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..1338
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /EC_number="2.4.3.9"
                     /note="isoform 1 is encoded by transcript variant 1;
                     lactosylceramide alpha-2,3-sialyltransferase;
                     CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase;
                     GM3 synthase; ST3Gal V; ganglioside GM3 synthase; ST3GalV;
                     sialyltransferase 9 (CMP-NeuAc:lactosylceramide
                     alpha-2,3-sialyltransferase; GM3 synthase);
                     sialyltransferase 9 (CMP-NeuAc:lactosylceramide
                     alpha-2,3-sialyltransferase)"
                     /codon_start=1
                     /product="lactosylceramide alpha-2,3-sialyltransferase
                     isoform 1"
                     /protein_id="NP_001385641.1"
                     /db_xref="GeneID:83505"
                     /db_xref="RGD:620875"
                     /translation="MRTEAAGGAARRPQKPRSQAAAPACRAMPNEFTSAKLRSDCSRT
                     SLQWYTQTQHKMRRPSLLLKDILKCMLVVFGVWLLYILKLNYTAEECDMKKLNYVDPA
                     RIKRAHRNTQEVFQKECRPGHAKKTMDLLFKGKYSMDLEPFVQKIPTASEAELKYDPP
                     FGFRKFSSKVQSLLDMLPEHDFPEHLRAKHCKRCVVIGNGGILHGLELGHALNQFDVV
                     IRLNSAPIEGYSEHVGNKTTIRMTYPEGAPLSDAEYYANDLFVAVLFKSVDFKWLQAM
                     VKNESLPFWIRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGHD
                     KNIPTIGIIAIVLATHLCDEVSLAGFGYDLSQPRTPLHYFDSQCMGAMNWQVMHNVTT
                     ETQFLQKLIKEGVVQDLSGGIH"
     exon            173..296
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /inference="alignment:Splign:2.1.0"
     exon            297..408
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /inference="alignment:Splign:2.1.0"
     exon            409..752
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /inference="alignment:Splign:2.1.0"
     exon            753..939
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1098
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..2301
                     /gene="St3gal5"
                     /gene_synonym="Siat9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgtccgggg ctgaatgggc gcgagcgcgg cgccgggggc gggctggggc gcggggcccg
       61 gggctggccg cttgccagcg ctccctccct agcatgcgca cggaggcggc gggcggcgcg
      121 gcgcggaggc cccagaagcc gcgaagccaa gcagcggcac ctgcctgccg agcaatgcca
      181 aatgagttca cctctgcaaa gctgagaagt gattgctcaa ggacctccct gcaatggtac
      241 acccagaccc agcacaagat gagaagaccc agcttgttat taaaagacat cctcaagtgc
      301 atgttggttg tgtttggagt gtggctcctg tacatcctca agttaaatta cactgctgaa
      361 gaatgtgaca tgaaaaaact gaattatgta gaccctgccc gaataaagag agctcataga
      421 aacactcagg aagtctttca gaaggaatgt cgtcctgggc acgcgaagaa aactatggat
      481 ctgttattta agggcaagta cagcatggac ttggagcctt tcgtgcagaa gatccccaca
      541 gccagtgaag ctgagctcaa gtatgacccg ccttttggat tccggaagtt ctccagtaaa
      601 gtccagagcc tcttggatat gctgcctgag cacgactttc ctgaacactt gagagccaag
      661 cactgcaagc gctgtgtggt tattgggaac gggggcatcc ttcacggact agagctgggc
      721 cacgcactca accagttcga tgtggtaata aggttaaaca gcgcaccaat tgagggttat
      781 tctgaacatg ttggaaataa aactactata aggatgactt acccagaggg tgctccactg
      841 tcggacgctg aatactacgc taatgacttg ttcgttgctg ttttatttaa gagtgttgat
      901 ttcaaatggc ttcaagcaat ggtgaaaaat gaaagcctgc cattttggat tcgtctcttc
      961 ttttggaagc aggtggcaga aaaaatccca ctccagccaa agcatttcag gattttgaac
     1021 ccagttatca tcaaagaaac tgccttcgac atccttcagt actcagagcc tcagtcaaga
     1081 ttctggggcc atgataagaa tatccccacg atcggcatca ttgccattgt cttggccacg
     1141 catctgtgtg atgaagttag cctggcaggc tttggatatg acctcagtca accaaggacc
     1201 cctctgcact actttgacag tcagtgcatg ggcgccatga actggcaagt catgcacaac
     1261 gtgaccacag agacccagtt cctccagaag ctcatcaagg agggcgtggt gcaggacctc
     1321 agcgggggca tccactgaga actttgaaca ccgcagacct cacttagcaa tgcagctgag
     1381 agctgtggtg agcagcctcc ccagggagtt taccctgcag ctgctttggc ctacagctag
     1441 tgtttttaaa ctcagtttta aaagaaaagg aaagaacaac agcaacaaca aaagttcagc
     1501 cctttacacc tctttgtcct atttatttga agtcagtgtt gggttttgca caattttgta
     1561 agttaatttt aagaatgggg atggaaagac ttttcaaaga gaatcgtatg gtttattgta
     1621 ttttaaagaa gtaatttaat ttgcaaaaac tgtacacatg tactctcccc aggtgttgag
     1681 gtgggaggag aggggcttct gcaccttcga tgatggcctc gatacctgac tgcgggttct
     1741 gcagctctgt ttggtagcac tgctggcagg gaaacttcct gcctcctgga tgaaggaagg
     1801 gtttactcat catcactggc agctgcagga agtcgggggc ctgataaaca agttcataac
     1861 ccctttctgc tagtccgtct gccagaagac tcagaggacc caagcagggc agctgttcca
     1921 caggcgagcc actgtcagct gagtaccgtg atgctgcccc aggatgggag aagccatgtc
     1981 gtcctacact gtcagggcac ttttcagctt ctggagaagt gtctgttctc tctgccctcc
     2041 caaagcactt ggtgttattt aaggcgtgag gctgtctgtc tgagatggtt catcagaatt
     2101 gtgacagcca tggggagcaa gacctctgca gatgaccaca ttgctaaagc actggagtga
     2161 accccccctg ttgtaactta agacccatcc tgaagtgccc tgaagtgccc accaaccaat
     2221 gtgaaaggag aatgaggaag gggagggaaa agaacagaaa gaaagaaaga aaaataataa
     2281 aagcttttga ggagcccctg t
//
