LOCUS       NM_001109255            4796 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus sarcospan (Sspn), mRNA.
ACCESSION   NM_001109255 XM_001075000 XM_575721
VERSION     NM_001109255.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4796)
  AUTHORS   Hagiwara,Y., Sasaoka,T., Araishi,K., Imamura,M., Yorifuji,H.,
            Nonaka,I., Ozawa,E. and Kikuchi,T.
  TITLE     Caveolin-3 deficiency causes muscle degeneration in mice
  JOURNAL   Hum Mol Genet 9 (20), 3047-3054 (2000)
   PUBMED   11115849
REFERENCE   2  (bases 1 to 4796)
  AUTHORS   Coral-Vazquez,R., Cohn,R.D., Moore,S.A., Hill,J.A., Weiss,R.M.,
            Davisson,R.L., Straub,V., Barresi,R., Bansal,D., Hrstka,R.F.,
            Williamson,R. and Campbell,K.P.
  TITLE     Disruption of the sarcoglycan-sarcospan complex in vascular smooth
            muscle: a novel mechanism for cardiomyopathy and muscular dystrophy
  JOURNAL   Cell 98 (4), 465-474 (1999)
   PUBMED   10481911
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Dec 11, 2015 this sequence version replaced NM_001109255.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ217310.1, SRR26643291.14097.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-225               JAXUCZ010000004.1  180627882-180628106
            226-312             JAXUCZ010000004.1  180652111-180652197
            313-4796            JAXUCZ010000004.1  180657806-180662289
FEATURES             Location/Qualifiers
     source          1..4796
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..4796
                     /gene="Sspn"
                     /gene_synonym="RGD1559723"
                     /note="sarcospan"
                     /db_xref="GeneID:500364"
                     /db_xref="RGD:1559723"
     exon            1..225
                     /gene="Sspn"
                     /gene_synonym="RGD1559723"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..678
                     /gene="Sspn"
                     /gene_synonym="RGD1559723"
                     /codon_start=1
                     /product="sarcospan"
                     /protein_id="NP_001102725.1"
                     /db_xref="GeneID:500364"
                     /db_xref="RGD:1559723"
                     /translation="MGRKPGPGAQELAEEEARTCCGCRFPLLLALLQLALGIAVTVLG
                     FLMASISPSLLVRDTPFWAGIIVCVVAYLGLFMLCVSYQVDERTCVQFSMKVFYFLLS
                     ALGLMVCTLAVAFAAHHYSLLAQFTCETSLDSCQCRLPSAEPLSRAFVYRDVTDCSSI
                     TGTFKLFLVIQMVLNLVCGLVCLLACFVMWKHRYQVFYVGVGLRSLMASDGQQQKA"
     exon            226..312
                     /gene="Sspn"
                     /gene_synonym="RGD1559723"
                     /inference="alignment:Splign:2.1.0"
     exon            313..4796
                     /gene="Sspn"
                     /gene_synonym="RGD1559723"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccagaggca ggcaccacca cgggaacatg gggcgaaagc cgggcccggg ggctcaggag
       61 ctggcagagg aggaggcaag gacctgttgc ggctgccgct ttccgctgct gctggcgctg
      121 ctgcagctgg ccctgggcat cgcggtgact gtgctgggct tcctcatggc gagcatcagc
      181 ccctccctgc tagtcagaga cactccgttc tgggctggga tcattgtctg cgtggtggcc
      241 taccttggac tgttcatgct ttgtgtctca taccaagttg acgagaggac gtgtgtccag
      301 ttttctatga aggtgtttta tttcctgctg agtgccctcg gcctgatggt ctgcacgctg
      361 gccgtggcct tcgccgccca ccactattcc ctgcttgcac agtttacctg tgaaacctcc
      421 ctggattctt gccagtgccg gctgccttcc gcggagcctc tcagcagggc ctttgtttac
      481 agggatgtga ctgactgtag cagcatcact ggtactttca aattgttctt agtcatccag
      541 atggttctaa acctggtctg tggcctggtg tgcttgctgg cttgctttgt gatgtggaaa
      601 cacaggtacc aggtctttta tgtgggtgtt gggctgcgct ccctgatggc ttctgatggc
      661 cagcaacaaa aggcctaaca ggttggctcc gtgggagaca agctcagaaa cagcacaccc
      721 accggccagc cgaggcgaaa accacaattt tttaaaggca aacttttgac aacaaatacc
      781 ttttcattct ctaaatgtgt atttttagat tttttttccc gcagaaaaca aaaaaaaaaa
      841 acttattttt ggatctctat tgtactttaa aaaacaaaac aaaacaaaac aaaaaacttt
      901 ttgtgaggac aggggtggag agacacggct cacaagggaa gaggactcac tgctcttgca
      961 aaggactcga gttcaagttc agttccagag cccaagttga gtggctcaca gctacctgta
     1021 tctccagttc cagggacact gggtgctgtg cgcatgcgcg cgcacatacg taattttaca
     1081 agccaactta tttttaacgt tctaatgaga aacaagattc aaattgactt ggtgaacacc
     1141 aaaaggaaaa gaacaacaga caagggacga atgaccttga gccggtgcta agctctggtg
     1201 cttatttagc cctacggctc tcccatcccc gccctcctct gcctttgtgt cagtccagtg
     1261 cgatggtgtg aactggcaac gcaggccatt ccctagaccc tagattcttc tagctctttc
     1321 tgccgcctgc cattatcccc ttggtgtctt gagaaaggtc taaggaaagc cgggtctcag
     1381 ttgagaggtt ttatttttca cagtggagat gtcttcaagg tatgaaatgg cttttttaaa
     1441 aaacctagta gaacaagaag gctcagtgat tctgaacacc tgggcagggt gcagccttcc
     1501 ggttgcctta gctctgatcc atgagtgggc tgcagcctcg agaggtctga ttcaccataa
     1561 ttgaaaggtg gtgctgttgt attcttaacg acgtagaaag tttaaaaata attatattat
     1621 gcctctagac tgtcatctaa aacaaatcat taagactaat ttccagctaa ttgttcatta
     1681 aaattatgct caggattctg tttaatgagc tctggctgtt cttaggcagc accgctggtg
     1741 ttaggaaaaa ttacagccac aagggaagat gtctgaagat ctacttttcc tggaagataa
     1801 ccaccacaaa aaaagaaaag aaaagaacac tcaggtttaa aacactctca gagaaaaaaa
     1861 caagagcatt tgtcatggga aatacttcta ttaatagctc gtctgtgata cattgagaaa
     1921 aatctcccct tgaccactaa gtacctttaa tggggattgg gaactacggg tgagtcctgt
     1981 caaacacatg gacttcctgt gaaatcctag tgatgatgac ttttacagtt gacctagaga
     2041 cagaatgcct cgaagtcctt gtttgggtga tatgtccaca gttagggcat ttaggttcag
     2101 tttagactta agtcacagta ctggttaaga caggctttgc tatgtaattg gtactaccca
     2161 gggcagacat gcatctgtgg gtctcagcga gtcccaggtc ccagctcagc caggcttgcc
     2221 cccactctgc ctatccatat actttcctgt cacaaaattc ccccctagag aacacatacc
     2281 cttttgcctt tgaggacttt atatgatgct gataatggaa tcagtccttc atgatccaca
     2341 caccctacct gaaggaaagg gatcaccact gactcttatt cctgattaac agatgcttaa
     2401 actttttgca ttctgacttg cttcccgatc actcgatcac tcgatcactc gggtcaaggc
     2461 agcccatcag agaggatggt gagtaaaatt ccatcagagg aacaggggtg gggcgggggt
     2521 ggggcagggg gctggtacat atctttaatc ccagcacttg gaaggtagaa ggagatggat
     2581 ttctgtgagt tcagagccag cctggtctac aaagaaagtt tctaggacag ccagagcaga
     2641 cagagaaacc ttgtcttgaa aaaaaccaaa accaaccaaa caaaaacaag ggaaaaaaaa
     2701 aaaaaaaaag gactgatctc agacaaaatt gcatgaacac agcacgaagt ttcctgatac
     2761 caacctggga tacctttagt gtttgttaag aataaccagc tctgggctct gaagatagtt
     2821 cagtaaccta agtccttgcc attccagtaa gaacttgatc ccttatagaa aggccaggca
     2881 tagtggcgtg gaggaagaga aggccacatc cctggggctt cctcaacagc catctctttt
     2941 tttttttttt ttggttcttt ttttcggaga tggggggacc gaactcaggg ccttgcgctt
     3001 cctaggtaag cgctctacca ctgagctaaa tccccagccc caacagccat ctttaattta
     3061 gcatttgaat tctgggtcca tgatgagaga gtttgtctca agggaaaaca aacaaactga
     3121 aaataaccca gagtggatag ctgacctctg gcctcacaca gttaagagga accaaattca
     3181 cattgacctg ggatagtgtc tatagaagca ggaatgtggt agaggatcca ggatgtcacg
     3241 ggctgtcctt tcaaagtgaa gctatcctcc agtccgtttc tgtgcaccca gcccggctga
     3301 aagcacacac agaatgcctt tgtccaacaa actcagcagg gttttgtttt tgttttctca
     3361 atgagaaaat gaagattccc cgcccagtta agttgcgcta tgatttgcaa acgactcacg
     3421 gggtggtggg ggtgggtggg cattttaaag ggtagaataa ttttagcctg cgggttccta
     3481 ctttctaaca caaccaagag ttggggtggt ttcagctcat gatacgacgt ctgcgcagaa
     3541 tgggggattt tactgttatg atcagatatc cttaactccc cagagagggg aaacgttgta
     3601 agtgaagaga aggagcagag cccgatgatg gggcccttcg ctggaagctt gctatatgct
     3661 gggatgtgta aggattgggt tgcatgaaaa acaaatggct ttgggctgga tttggagtat
     3721 tttgacgtta tgttttgcaa atattgaagc ttcagtaagg gcaacagaga aggagcaggc
     3781 acacagcttc tcacttagca aaatgttaca cttcaaatct gtcgcagagc caggacggtg
     3841 actgtgcctt ccaaactgta gagcagtgag ctttgagcag ctcccccctc ccccagcctc
     3901 cttcaggagg attaaatgaa tcaagacttt tccaagagga gaaatggcca gggcttggga
     3961 taggaatacg gccacctggg tttacagact gtaactgagc ccactcaacg ggtctgcgcc
     4021 tttacggtga ctgccatctg tggctccaaa ctccatccaa attggtgtag gcagcacctt
     4081 ggagccgtgc ctaaaccgta gctactcaaa agccctagaa actgtagtca agtaacaggc
     4141 atcacatgcc cctatttgga tgcagaactt agatattctc tttcgaccgc cttccaatgt
     4201 gttcctacag tggaattcca ttctatatta cttttatcca tgtccaagac ctgaggatct
     4261 cctgatactt cttcactcat gtctctgtgc attatatctg gggcatattt atgaaactgc
     4321 cttgataaaa gcgacccaag gggtgtcagg aggggcaact ctgaaggggc tacttaaaga
     4381 cgatcagaaa tgaacttgaa agctgtccat cacttgcaaa catgaactgt gtcttgatat
     4441 ttcctgatga ctgtctctga actattaccg tgtgatcacc tctgtataaa tatgccactg
     4501 gattttactc ttgttaaccc agaatgtgct ttagctgtgt agtgtaagtt cagcctatct
     4561 gacggccaac tgcttagtgt tgaagtcact gaaaagaact cacgtcttct aattttcttg
     4621 tctcaagtga gcactgcctc tttcagagcc atgggtctgc attacggggc tgtaatctcc
     4681 tttcctggcc ttgatcaaat caagagtaga agatggagtg tttctataca cttgaggtgg
     4741 ttatttttaa agggtgtgtg tttcctttct taataaactt ttcataatcc acaaag
//
