LOCUS       NM_183328                583 bp    mRNA    linear   ROD 04-APR-2024
DEFINITION  Rattus norvegicus single stranded DNA binding protein 1 (Ssbp1),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_183328 XM_008762828 XM_342666
VERSION     NM_183328.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Ciesielski,G.L., Bermek,O., Rosado-Ruiz,F.A., Hovde,S.L.,
            Neitzke,O.J., Griffith,J.D. and Kaguni,L.S.
  TITLE     Mitochondrial Single-stranded DNA-binding Proteins Stimulate the
            Activity of DNA Polymerase gamma by Organization of the Template
            DNA
  JOURNAL   J Biol Chem 290 (48), 28697-28707 (2015)
   PUBMED   26446790
REFERENCE   2  (bases 1 to 583)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 583)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 583)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   5  (bases 1 to 583)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   6  (bases 1 to 583)
  AUTHORS   Korhonen,J.A., Pham,X.H., Pellegrini,M. and Falkenberg,M.
  TITLE     Reconstitution of a minimal mtDNA replisome in vitro
  JOURNAL   EMBO J 23 (12), 2423-2429 (2004)
   PUBMED   15167897
REFERENCE   7  (bases 1 to 583)
  AUTHORS   Korhonen,J.A., Gaspari,M. and Falkenberg,M.
  TITLE     TWINKLE Has 5' -> 3' DNA helicase activity and is specifically
            stimulated by mitochondrial single-stranded DNA-binding protein
  JOURNAL   J Biol Chem 278 (49), 48627-48632 (2003)
   PUBMED   12975372
REFERENCE   8  (bases 1 to 583)
  AUTHORS   Gupta,S. and Van Tuyle,G.C.
  TITLE     The gene and processed pseudogenes of the rat mitochondrial
            single-strand DNA-binding protein: structure and promoter strength
            analyses
  JOURNAL   Gene 212 (2), 269-278 (1998)
   PUBMED   9611270
REFERENCE   9  (bases 1 to 583)
  AUTHORS   Tiranti,V., Rocchi,M., DiDonato,S. and Zeviani,M.
  TITLE     Cloning of human and rat cDNAs encoding the mitochondrial
            single-stranded DNA-binding protein (SSB)
  JOURNAL   Gene 126 (2), 219-225 (1993)
   PUBMED   8482537
REFERENCE   10 (bases 1 to 583)
  AUTHORS   Hoke,G.D., Pavco,P.A., Ledwith,B.J. and Van Tuyle,G.C.
  TITLE     Structural and functional studies of the rat mitochondrial single
            strand DNA binding protein P16
  JOURNAL   Arch Biochem Biophys 282 (1), 116-124 (1990)
   PUBMED   2221914
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM064958.1.
            
            On or before Apr 13, 2016 this sequence version replaced
            XM_008762828.1, NM_183328.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM064958.1, SRR8487227.26027.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-583               FM064958.1         6-588
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q23"
     gene            1..583
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /note="single stranded DNA binding protein 1"
                     /db_xref="GeneID:54304"
                     /db_xref="RGD:3760"
     exon            1..33
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /inference="alignment:Splign:2.1.0"
     exon            34..96
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..519
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /note="single-stranded DNA-binding protein, mitochondrial;
                     single strand DNA-binding protein P16; single-stranded DNA
                     binding protein 1, mitochondrial"
                     /codon_start=1
                     /product="single-stranded DNA-binding protein,
                     mitochondrial precursor"
                     /protein_id="NP_899157.2"
                     /db_xref="GeneID:54304"
                     /db_xref="RGD:3760"
                     /translation="MFRRPVLQVFRQFVRQESEVASSLVLERSLNRVQLLGRVGQDPV
                     MRQVEGKNPVTIFSLATNEMWRSGDNEAYQMGDVSQKTTWHRISVFRPGLRDVAYQYV
                     KKGARIFVEGKVDYGEYMDKNNVRRQATTIIADNIIFLSDQAREKP"
     exon            97..157
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /inference="alignment:Splign:2.1.0"
     exon            158..298
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /inference="alignment:Splign:2.1.0"
     exon            299..386
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /inference="alignment:Splign:2.1.0"
     exon            387..475
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /inference="alignment:Splign:2.1.0"
     exon            476..583
                     /gene="Ssbp1"
                     /gene_synonym="Mt-SSB; mtSSB; Ssbp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgagccgct ggcagtctgg gcttgcgcgt caggaaaagc ctaaagatta ggttataaga
       61 aaaaccgaag ccatgtttcg aagacctgtg ttacaggtat ttcgtcagtt tgtaagacag
      121 gagtctgaag tagccagcag tttggttctt gaacgatctt tgaatcgtgt tcagttactt
      181 gggcgagtag gtcaggaccc tgtcatgaga caggtggagg gaaaaaaccc agtcacgata
      241 ttttctctag caacaaatga gatgtggcga tcaggggaca atgaagcata ccaaatgggt
      301 gacgtcagtc aaaagacaac atggcacaga atatcagtgt ttcggccagg cctcagagat
      361 gtggcttatc agtatgtgaa aaagggggct cgtatatttg tggaaggcaa agtggactat
      421 ggtgaataca tggataaaaa caatgtgagg cggcaagcaa caacaatcat agctgataac
      481 attatatttc tgagtgacca ggcaagagaa aagccataga acggatgatt cttcgttgat
      541 cattgtttgg tacagtctcc tttgcaaatc atgtacagtc tat
//
