LOCUS       NM_138918               4119 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus SS18L1 subunit of BAF chromatin remodeling
            complex (Ss18l1), mRNA.
ACCESSION   NM_138918
VERSION     NM_138918.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4119)
  AUTHORS   Du,A., Li,L., Jiao,Z., Zhu,G., Peng,T. and Li,H.
  TITLE     Protein expression pattern of calcium-responsive transactivator in
            early postnatal and adult testes
  JOURNAL   Histochem Cell Biol 155 (4), 491-502 (2021)
   PUBMED   33398438
  REMARK    GeneRIF: Protein expression pattern of calcium-responsive
            transactivator in early postnatal and adult testes.
REFERENCE   2  (bases 1 to 4119)
  AUTHORS   Alaghband,Y., Kramar,E., Kwapis,J.L., Kim,E.S., Hemstedt,T.J.,
            Lopez,A.J., White,A.O., Al-Kachak,A., Aimiuwu,O.V.,
            Bodinayake,K.K., Oparaugo,N.C., Han,J., Lattal,K.M. and Wood,M.A.
  TITLE     CREST in the Nucleus Accumbens Core Regulates Cocaine Conditioned
            Place Preference, Cocaine-Seeking Behavior, and Synaptic Plasticity
  JOURNAL   J Neurosci 38 (44), 9514-9526 (2018)
   PUBMED   30228227
  REMARK    GeneRIF: CREST in the nucleus accumbens core is required for
            cocaine-induced conditioned place preference, synaptic plasticity
            and cocaine-seeking behavior.
REFERENCE   3  (bases 1 to 4119)
  AUTHORS   Holloway,J.K., Sun,X., Yokoo,R., Villeneuve,A.M. and Cohen,P.E.
  TITLE     Mammalian CNTD1 is critical for meiotic crossover maturation and
            deselection of excess precrossover sites
  JOURNAL   J Cell Biol 205 (5), 633-641 (2014)
   PUBMED   24891606
REFERENCE   4  (bases 1 to 4119)
  AUTHORS   Staahl,B.T., Tang,J., Wu,W., Sun,A., Gitler,A.D., Yoo,A.S. and
            Crabtree,G.R.
  TITLE     Kinetic analysis of npBAF to nBAF switching reveals exchange of
            SS18 with CREST and integration with neural developmental pathways
  JOURNAL   J Neurosci 33 (25), 10348-10361 (2013)
   PUBMED   23785148
REFERENCE   5  (bases 1 to 4119)
  AUTHORS   Men,X., Peng,L., Wang,H., Zhang,W., Xu,S., Fang,Q., Liu,H., Yang,W.
            and Lou,J.
  TITLE     Involvement of the Ca2+-responsive transactivator in high
            glucose-induced beta-cell apoptosis
  JOURNAL   J Endocrinol 216 (2), 231-243 (2013)
   PUBMED   23160962
  REMARK    GeneRIF: The results indicated that CREST is implicated in
            beta-cell apoptosis induced by culture in high glucose.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4119)
  AUTHORS   Yang,F., Gell,K., van der Heijden,G.W., Eckardt,S., Leu,N.A.,
            Page,D.C., Benavente,R., Her,C., Hoog,C., McLaughlin,K.J. and
            Wang,P.J.
  TITLE     Meiotic failure in male mice lacking an X-linked factor
  JOURNAL   Genes Dev 22 (5), 682-691 (2008)
   PUBMED   18316482
REFERENCE   7  (bases 1 to 4119)
  AUTHORS   Yang,F., Eckardt,S., Leu,N.A., McLaughlin,K.J. and Wang,P.J.
  TITLE     Mouse TEX15 is essential for DNA double-strand break repair and
            chromosomal synapsis during male meiosis
  JOURNAL   J Cell Biol 180 (4), 673-679 (2008)
   PUBMED   18283110
REFERENCE   8  (bases 1 to 4119)
  AUTHORS   Pradhan,A. and Liu,Y.
  TITLE     A multifunctional domain of the calcium-responsive transactivator
            (CREST) that inhibits dendritic growth in cultured neurons
  JOURNAL   J Biol Chem 280 (26), 24738-24743 (2005)
   PUBMED   15866867
  REMARK    GeneRIF: analysis of the CREST domain that inhibits dendritic
            growth in cultured neurons
REFERENCE   9  (bases 1 to 4119)
  AUTHORS   Pradhan,A. and Liu,Y.
  TITLE     The calcium-responsive transactivator recruits CREB binding protein
            to nuclear bodies
  JOURNAL   Neurosci Lett 370 (2-3), 191-195 (2004)
   PUBMED   15488321
REFERENCE   10 (bases 1 to 4119)
  AUTHORS   Aizawa,H., Hu,S.C., Bobb,K., Balakrishnan,K., Ince,G., Gurevich,I.,
            Cowan,M. and Ghosh,A.
  TITLE     Dendrite development regulated by CREST, a calcium-regulated
            transcriptional activator
  JOURNAL   Science 303 (5655), 197-202 (2004)
   PUBMED   14716005
  REMARK    GeneRIF: calcium activation of CREST-mediated transcription helps
            regulate neuronal morphogenesis
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 22, 2020 this sequence version replaced NM_138918.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.16612.1,
                                           SRR26643429.14912.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                JAXUCZ010000003.1  187521616-187521692
            78-154              JAXUCZ010000003.1  187528956-187529032
            155-239             JAXUCZ010000003.1  187529809-187529893
            240-384             JAXUCZ010000003.1  187531362-187531506
            385-582             JAXUCZ010000003.1  187532065-187532262
            583-747             JAXUCZ010000003.1  187534071-187534235
            748-849             JAXUCZ010000003.1  187534580-187534681
            850-942             JAXUCZ010000003.1  187535603-187535695
            943-1062            JAXUCZ010000003.1  187537506-187537625
            1063-1190           JAXUCZ010000003.1  187538610-187538737
            1191-4119           JAXUCZ010000003.1  187539945-187542873
FEATURES             Location/Qualifiers
     source          1..4119
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..4119
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /note="SS18L1 subunit of BAF chromatin remodeling complex"
                     /db_xref="GeneID:192352"
                     /db_xref="RGD:621847"
     exon            1..77
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..1217
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /note="calcium-responsive transactivator; SS18-like
                     protein 1; SS18L1, nBAF chromatin remodeling complex
                     subunit; synovial sarcoma translocation gene on chromosome
                     18-like 1"
                     /codon_start=1
                     /product="calcium-responsive transcription coactivator"
                     /protein_id="NP_620273.2"
                     /db_xref="GeneID:192352"
                     /db_xref="RGD:621847"
                     /translation="MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILDYQSKGKT
                     AECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNMNLGPGALSQSGSSQGLHPQ
                     GSLSDTVSTGLPPASLMQGQIGNGPNHVSMQQTAQSTLPTTSMSMSGSGHGTGPGYSH
                     SGPTSQSVPMQGQGAISNYVSRTNINMQSNPVSMMHQQAATSHYNSAQGGSQHYQGQA
                     PIAMMGQGGQGGSMMGQRPMAPYRPSQQGSSQQYLGQEEYYSEQYSHSQGSAEPMSQQ
                     YYPDGHSDYAYQQSSYTEQSYDRSFEDPTQHYYEGGNSQYSQQQAGYQQGTAQQQTYS
                     QQQYPNQQSYPGQQQGYGPAQGAPSQYSGYQQGQGQQYGSYRTSQTGPSAQQQRPYGY
                     EQGQYGNYQQ"
     exon            78..154
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            155..239
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            240..384
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            385..582
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            583..747
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            748..849
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            850..942
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1062
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1190
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..4119
                     /gene="Ss18l1"
                     /gene_synonym="CREST"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccaccaccat gtccgtggcc ttcgcgtcgg cgcggccgag aggcaaaggg gaggtcactc
       61 agcagaccat ccagaagatg ctggatgaga accaccacct gatccagtgc atcctggact
      121 accagagcaa gggcaagaca gccgagtgca cccagtacca gcagatcctg caccggaacc
      181 tggtctacct ggccaccata gcagattcca accagaacat gcagtctctg cttcccgcgc
      241 ctccaaccca gaacatgaac ctcgggcccg gagcactgag tcagagcggt tccagccagg
      301 gcctgcaccc ccagggcagc ctcagtgaca ccgtcagcac aggcctgccc cctgcctccc
      361 tcatgcaggg ccagatcggt aacggtccaa accacgtgtc catgcagcag acggctcaga
      421 gcacgctgcc cacaacctcc atgagtatgt caggcagtgg ccatggtact gggcctgggt
      481 acagccactc gggacctacg tcgcagagtg tccccatgca aggccaaggt gccatcagca
      541 actatgtgtc tcggaccaac atcaacatgc agtccaaccc agtctccatg atgcaccagc
      601 aggcggccac gtcccactac aactcagcgc agggtggaag ccagcattac cagggccagg
      661 cgcccattgc catgatgggc cagggtggcc aaggaggcag catgatgggg cagcggccca
      721 tggcgcccta ccgaccctct cagcaaggct cttcccagca gtacctgggc caggaggagt
      781 actacagtga acagtacagc cacagccagg gttctgcaga gcccatgagt caacagtact
      841 acccagatgg ccacagtgac tacgcctatc agcagtcgtc ctacacagag cagagctacg
      901 accgttcatt tgaggacccc acacagcact actatgaggg gggaaactcc cagtacagtc
      961 agcagcaggc tgggtaccag cagggcacag cacagcagca gacctactcc cagcagcagt
     1021 atcccaacca gcagagctac cctggacagc agcagggcta cggccctgcc cagggagccc
     1081 cttcacagta ctcaggctac cagcaaggac aaggtcagca gtatggaagc tacagaacgt
     1141 cgcagacggg accttctgcc cagcagcagc ggccttacgg ctatgagcag ggccagtatg
     1201 gaaattacca gcaataaagg acaagcgttg gctttggacc cttcatagta ggatgagcca
     1261 gtgacagttc cgatgagtaa tgacacgttg gtcaccctct ttgcccagtg ccgtgtctgc
     1321 atgagaggca ggctcgtttc gtgctgggtg tgatgctgtg cgtaccactg gctgaaatgg
     1381 cgtgacatgt ttggtgctgt gtaaagtatt gtatatgggt gcgatgggga ggttgtcctg
     1441 tttgtgtccc ctgtccccct ccctgatgtt cttagctagc ttcggggggt cacagagtca
     1501 tcgcgtgttc tatgcccagt gatgagacag tatctaagag acatcatggc ccacgctacc
     1561 atgaacagac ccagtctgcc cccactcata ccattgttgt aagcggaccg ttttgagatg
     1621 tttcttcaac tggcggctca tagcttgacg tacgtacgac gctgggtggc catctcctct
     1681 gtgcctaagt agggcctggg gacaccttct gtgtcttggg tcatgtcact gtaacaagga
     1741 aaatgtgctt cgtgtgcaaa gaccatgagc tgtcctttcc aggacttggc agtcgcctgt
     1801 gtctctccag gttccctgat ccctgagtac gtctttgtgg tagagagtga agagggatcg
     1861 gtgactgtat tccagataac tgccaccgtg atgggtgatg gcgtcgggag gggagccttc
     1921 cctgaggagg gcggtgtctg aagagcaagt ctcgctgtct cccggctgct tgtgcctagt
     1981 gtggctttgg cccttgttta tttggtgtca tctgtaggct ttgagtgttg ccggaaccta
     2041 aatttaaaga caatttaaag tactcgtgtt taattttatg agcagttggc aagtgtttat
     2101 tttacttttc ccggaccttt gagttcagat tgccaagcag atgctccttt gcctttaggg
     2161 agctctgaaa cccacactgc attttttttt ttttttggtt ctttttttcg gagctgtgga
     2221 ccgaacccag ggccttgcgc tcccacactg catttttaat gactccaaat aacttgatta
     2281 catccactca aatgaaaagg acaagtttca tacagcgaaa attgagtgac tttttttttt
     2341 ttttttacgt ctttagggtg tttaatctca ttttaattct gtgcaaacag gagaggcagc
     2401 ctctttgaaa aggttctgtc agaggaaaac accacatata gtgtagcatg cgtatttctc
     2461 agcatccttt tggataataa tgatgtgact atgagaaaaa gaagaagaag aaggaaaaaa
     2521 ccttcaagat aagtgctaag aacaaccaag aacatacaaa accatctctg aggatgcagg
     2581 gcttggtgcc atcgggcctg tcagccggga tgctttccct ttatctgtgt cttatatgta
     2641 gcccagactg gcctcaaact cactacataa ctgaggccga acttaaccat cctcctgcct
     2701 ccactcccaa gtactgagac cataggtgtg tactaccatg cctgagtgtt tccagttgat
     2761 tgtttttaaa atataaaact tatcggtagc tcaatgggta aggccctttt gtggggtttg
     2821 cttgaactaa tcttgatggt cttgccagaa aatacagtgc aagctccgtt ttactcacag
     2881 aagagcaagg gccgcattaa aagacttgtc tgtggtagtt tccatattaa tctaggatgc
     2941 cctccctctc ctgtgggact tgatatcaac agccatgggt gtatatgtct cctaggcata
     3001 gggtttagga aacacacagg ctggctacgt gacggtttta acttcataga aatgagtttc
     3061 tgatcgatat gtgtcagaag tgatggcaac ttcattttag ggactcagtc tcttttgctc
     3121 ctttcctttc tggcagtttc tataaaacca gtcttgcaag ctcagctggg ggctaaaata
     3181 tctcattgaa aacgtcaaaa cattttaagt aactgtgaaa atggttttta ttacttgcca
     3241 atctgggaat atgccttctg cgtgtgcata tatgtgtatg tgtgtatctg tgtgtgtgcg
     3301 tttgtgtatg ttaaagtgct gtattagtgt gtgtatgtgt gtgtatgtgt atgttaagtg
     3361 ctgtatttag tgtttgttaa tactttttga aagaaaagga cacttaaaaa atattatcac
     3421 cccaaaagtt caatctgaaa tgtcttacat taagaatttc ttgaatgttg tgtatatatt
     3481 tttaaaagca ctttgtgaaa tagtttatac atttatttcc taatttatac ctgattttgg
     3541 tgttaatata tttaatgatt aataataatg tttatttaat gttttgttca tttttatgta
     3601 attttgtggg gaaaggtgat gccagtgttt ttcattgcct gtattatagc ttttcttctg
     3661 ttacatgaat gtttggaaag tcctaggctg aaatgaaccc tttgtgcggg cgtggttgac
     3721 tgtgttttgt tttctgtgac ccctcctact gaaggccaga aaagatttgg aaatcactgc
     3781 tcattcttcc tcctgtttcc caacatccat tcaacacttg gtgaacttga ccactgatga
     3841 ctggggtttt cagatgtgca gaccactacc cgatgcttag cagaagctgc gcacgtcagg
     3901 ggccacggtt gtacggacac ctcaacagac ttagcagata gcacagtggg agatgggaaa
     3961 agtccgcaga ggtactggat agacacaggc ctggcccagg aaggaggtgt cttcctctcc
     4021 tgtcctacca gttttcagac gtgggcttaa gtaatgagtg tccattcaaa cttgtaaaaa
     4081 gaggacgact ttccattaaa aacacttttt tagccatta
//
