LOCUS       NM_001047907            2870 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus serine and arginine rich splicing factor 3
            (Srsf3), mRNA.
ACCESSION   NM_001047907 XM_001069454 XM_342107
VERSION     NM_001047907.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2870)
  AUTHORS   Roundtree,I.A., Luo,G.Z., Zhang,Z., Wang,X., Zhou,T., Cui,Y.,
            Sha,J., Huang,X., Guerrero,L., Xie,P., He,E., Shen,B. and He,C.
  TITLE     YTHDC1 mediates nuclear export of N6-methyladenosine methylated
            mRNAs
  JOURNAL   Elife 6, e31311 (2017)
   PUBMED   28984244
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2870)
  AUTHORS   Xiao,W., Adhikari,S., Dahal,U., Chen,Y.S., Hao,Y.J., Sun,B.F.,
            Sun,H.Y., Li,A., Ping,X.L., Lai,W.Y., Wang,X., Ma,H.L., Huang,C.M.,
            Yang,Y., Huang,N., Jiang,G.B., Wang,H.L., Zhou,Q., Wang,X.J.,
            Zhao,Y.L. and Yang,Y.G.
  TITLE     Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing
  JOURNAL   Mol Cell 61 (4), 507-519 (2016)
   PUBMED   26876937
  REMARK    Erratum:[Mol Cell. 2016 Mar 17;61(6):925]
REFERENCE   3  (bases 1 to 2870)
  AUTHORS   Iborra,S., Hirschfeld,M., Jaeger,M., Zur Hausen,A., Braicu,I.,
            Sehouli,J., Gitsch,G. and Stickeler,E.
  TITLE     Alterations in expression pattern of splicing factors in epithelial
            ovarian cancer and its clinical impact
  JOURNAL   Int J Gynecol Cancer 23 (6), 990-996 (2013)
   PUBMED   23748175
REFERENCE   4  (bases 1 to 2870)
  AUTHORS   Walsh,C.M., Suchanek,A.L., Cyphert,T.J., Kohan,A.B.,
            Szeszel-Fedorowicz,W. and Salati,L.M.
  TITLE     Serine arginine splicing factor 3 is involved in enhanced splicing
            of glucose-6-phosphate dehydrogenase RNA in response to nutrients
            and hormones in liver
  JOURNAL   J Biol Chem 288 (4), 2816-2828 (2013)
   PUBMED   23233666
  REMARK    GeneRIF: Serine arginine splicing factor 3 is involved in enhanced
            splicing of glucose-6-phosphate dehydrogenase RNA in response to
            nutrients and hormones in liver
REFERENCE   5  (bases 1 to 2870)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   6  (bases 1 to 2870)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   7  (bases 1 to 2870)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   8  (bases 1 to 2870)
  AUTHORS   Watanuki,T., Funato,H., Uchida,S., Matsubara,T., Kobayashi,A.,
            Wakabayashi,Y., Otsuki,K., Nishida,A. and Watanabe,Y.
  TITLE     Increased expression of splicing factor SRp20 mRNA in bipolar
            disorder patients
  JOURNAL   J Affect Disord 110 (1-2), 62-69 (2008)
   PUBMED   18281098
REFERENCE   9  (bases 1 to 2870)
  AUTHORS   Bavelloni,A., Faenza,I., Cioffi,G., Piazzi,M., Parisi,D., Matic,I.,
            Maraldi,N.M. and Cocco,L.
  TITLE     Proteomic-based analysis of nuclear signaling: PLCbeta1 affects the
            expression of the splicing factor SRp20 in Friend erythroleukemia
            cells
  JOURNAL   Proteomics 6 (21), 5725-5734 (2006)
   PUBMED   17022104
REFERENCE   10 (bases 1 to 2870)
  AUTHORS   Gillen,C., Gleichmann,M., Spreyer,P. and Muller,H.W.
  TITLE     Differentially expressed genes after peripheral nerve injury
  JOURNAL   J Neurosci Res 42 (2), 159-171 (1995)
   PUBMED   8568916
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001047907.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ480748.1, SRR26643286.46556.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                JAXUCZ010000020.1  7093585-7093683
            100-307             JAXUCZ010000020.1  7096901-7097108
            308-442             JAXUCZ010000020.1  7098549-7098683
            443-481             JAXUCZ010000020.1  7100844-7100882
            482-568             JAXUCZ010000020.1  7101042-7101128
            569-2870            JAXUCZ010000020.1  7101216-7103517
FEATURES             Location/Qualifiers
     source          1..2870
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2870
                     /gene="Srsf3"
                     /gene_synonym="Sfrs3"
                     /note="serine and arginine rich splicing factor 3"
                     /db_xref="GeneID:361814"
                     /db_xref="RGD:1309233"
     exon            1..99
                     /gene="Srsf3"
                     /gene_synonym="Sfrs3"
                     /inference="alignment:Splign:2.1.0"
     exon            100..307
                     /gene="Srsf3"
                     /gene_synonym="Sfrs3"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..596
                     /gene="Srsf3"
                     /gene_synonym="Sfrs3"
                     /note="splicing factor, arginine/serine-rich 3 (SRp20)"
                     /codon_start=1
                     /product="serine/arginine-rich splicing factor 3"
                     /protein_id="NP_001041372.1"
                     /db_xref="GeneID:361814"
                     /db_xref="RGD:1309233"
                     /translation="MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARN
                     PPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRD
                     DYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRS
                     NERK"
     exon            308..442
                     /gene="Srsf3"
                     /gene_synonym="Sfrs3"
                     /inference="alignment:Splign:2.1.0"
     exon            443..481
                     /gene="Srsf3"
                     /gene_synonym="Sfrs3"
                     /inference="alignment:Splign:2.1.0"
     exon            482..568
                     /gene="Srsf3"
                     /gene_synonym="Sfrs3"
                     /inference="alignment:Splign:2.1.0"
     exon            569..2870
                     /gene="Srsf3"
                     /gene_synonym="Sfrs3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggagagag agcatctttg gaagcagtgc cagagggaac cgggtgggcc tgtcggagcg
       61 ttaggatttg agcttgggcc ttttgaatct aggatctcga aatgcatcgt gattcctgtc
      121 ccttggactg taaggtttat gtaggtaatc ttggaaacaa tgggaacaag actgaattag
      181 aacgggcttt tggctattat ggaccactcc gaagtgtgtg ggttgctcga aaccctcctg
      241 gctttgcttt cgtcgaattt gaggatcccc gagatgctgc tgatgctgtc cgagagctag
      301 atggaagaac actatgtggc tgccgtgtaa gagtggaact gtcgaatggt gaaaagagaa
      361 gtcggaatcg tggcccacct ccctcttggg gtcgtcgtcc tcgagatgat taccgcagga
      421 ggagtcctcc acctcggcgc agatccccaa gaaggagaag cttttcgcga agccggagca
      481 ggtctctttc tagagatagg agaagagaaa ggtctctgtc tcgtgagaga aatcacaagc
      541 cgtctcgatc cttctctagg tctcgtagcc gatctaggtc aaatgaaagg aaatagaaga
      601 ccagttggca aaagtggtgt acaggaaata acttcatttg acaggagtat gtacaggaaa
      661 ttaaagtttt gtttgagact tcataagctt ggtgcatttt taagatgttt tagctgttca
      721 aatttgtttt gtctcttgga acagtgacac acaaaacgat gtaattctct atggtttcaa
      781 atggatcata tgaggcatgt gatattaaga attgttactt tacaatgttc ccttaagcga
      841 gattgaattt tctttgaatt ttagtttttc atagactgaa ataaacctag atcctgccca
      901 gtttgaagtg atgtactgat gacgtcaagc acctagcgga aatggactaa agctgtagtt
      961 cccctagtgg ctgagacaca gtgtggcact gtgggtgaaa tggtgagcag cctttaaagg
     1021 ctgctgtgaa cacaaccaac agataaaggg taggaaccac actctgaagg ttttcacagt
     1081 ggttccttcc tggttgctgt atggggatgc agagctgtct aacatcttta tttggaaatg
     1141 taaaactaag ataccagtgt cctatcagtt taagggtaca ttgtagagct gaactcagtt
     1201 actgtgcaag attttttttc atgctgtcat ttgtaatatg tttgtgagaa tccttgggat
     1261 taaagttttg gttacaaatt gttgtttaac ttgaaagcct gtttttcctt gcacactcaa
     1321 aatctgtgag cttggtatca agtccaggta taacattcct attggaaacc atacttatat
     1381 tttcttgtaa agtgcttttg aattaataaa atactagcat aattgtgtag taagcagtca
     1441 gctgagtgaa cccccattgc tcttatccct ggaaagcagt tggttaccca gttcgttctt
     1501 tgtaagaaac aactgagagg cactgcgtta gcgaaggaat tttcccccct ttgcttgtca
     1561 cctatgagag ccatgttttg ggtgtggaag tcagttcagg atcatggcag ttagtgacta
     1621 acattttata aagcaccaat ctatgacaca ctgtaaatcc tttaagttgc ccttaaaaag
     1681 tggctttgat cttcagcatg aagtcattga cattcaacaa aattttataa ttcgttccat
     1741 tttataactt gaggtgttgc atgggattcc agattgatcc atcatgatgt aaaatccaca
     1801 ctggttaatt gtgatgatgc acagttgaat atggaggcat gtaaaccttt tctcttagaa
     1861 atctggagga gctgtggttc cagggggttt tttgtgtgca attagattaa atcataatgc
     1921 aacagtctcg tggcttaagt ttccttaaat gtgttctttt gagatagttt ttgggattcc
     1981 actgtactga ctttgtcttt gtaagatgcc attgcacaag gttcaatctg taagcttata
     2041 aatcccccaa aatttgttat ctttttacaa taaatttcag taagaaagga gagaattgtg
     2101 ttcagaaggt tccaacatga gcctttgaaa gaggtagcca tattcaaaga agatacttta
     2161 gattccctgt taattgttag gagtgcgctt tatccttcag ggtagggttg gagtcaagcc
     2221 tgttccttgt aattgtaggt cacattagct actctttttt tttttttttt ccggagctgg
     2281 ggaccaaccc agggccccac attagctact cttgatcgtt ttctgagtgt catactaagt
     2341 tagggtgact gcaggtgttt cctggaggtc attattagtg actgagaaag gcacctgaga
     2401 ttgggattct cttttcattg tgggtcacct cagaggtaca tactttacag cacggtgtag
     2461 gtgcccgccc tttaccatcc aggttcctta agtgtcatgg tggcatctcc accctgtatt
     2521 ggaccatagg cactgaccga ggcatgaagc tgaacaggag atcttagtaa ttgtttttga
     2581 ctctcagcct cactctggca tgttgctgct taattagaaa tgaatggtgt tgcttataga
     2641 agtctaaggt gctgcatgta taggtgagaa acggccatag tctccccagt cactgcgtta
     2701 gtgccttgtc ttaaatgggc tttgcctttc ttagtccaga tgggactttg ataccagaca
     2761 agtcatctct tccagtgtat attttttgta ctgccagact gttgccttct ggttttcttt
     2821 tgggggaggg acaaaaaaga tttttattaa agacactgac tttaagctgg
//
