LOCUS       NM_001106157             784 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus signal recognition particle 19 (Srp19), mRNA.
ACCESSION   NM_001106157 XM_001060949 XM_214599
VERSION     NM_001106157.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 784)
  AUTHORS   Becker,M.M., Lapouge,K., Segnitz,B., Wild,K. and Sinning,I.
  TITLE     Structures of human SRP72 complexes provide insights into SRP RNA
            remodeling and ribosome interaction
  JOURNAL   Nucleic Acids Res 45 (1), 470-481 (2017)
   PUBMED   27899666
REFERENCE   2  (bases 1 to 784)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 784)
  AUTHORS   Yoshida,M., Kabe,Y., Wada,T., Asai,A. and Handa,H.
  TITLE     A new mechanism of
            6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,
            1-c)quinolin-7-one dihydrochloride (TAS-103) action discovered by
            target screening with drug-immobilized affinity beads
  JOURNAL   Mol Pharmacol 73 (3), 987-994 (2008)
   PUBMED   18089836
REFERENCE   4  (bases 1 to 784)
  AUTHORS   Maity,T.S. and Weeks,K.M.
  TITLE     A threefold RNA-protein interface in the signal recognition
            particle gates native complex assembly
  JOURNAL   J Mol Biol 369 (2), 512-524 (2007)
   PUBMED   17434535
REFERENCE   5  (bases 1 to 784)
  AUTHORS   Politz,J.C., Yarovoi,S., Kilroy,S.M., Gowda,K., Zwieb,C. and
            Pederson,T.
  TITLE     Signal recognition particle components in the nucleolus
  JOURNAL   Proc Natl Acad Sci U S A 97 (1), 55-60 (2000)
   PUBMED   10618370
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC167043.1.
            
            On May 11, 2008 this sequence version replaced NM_001106157.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167043.1, CO405756.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..784
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..784
                     /gene="Srp19"
                     /note="signal recognition particle 19"
                     /db_xref="GeneID:291685"
                     /db_xref="RGD:1308437"
     exon            1..50
                     /gene="Srp19"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..444
                     /gene="Srp19"
                     /EC_number="3.6.5.4"
                     /codon_start=1
                     /product="signal recognition particle 19 kDa protein"
                     /protein_id="NP_001099627.1"
                     /db_xref="GeneID:291685"
                     /db_xref="RGD:1308437"
                     /translation="MACAAARSPADQDRFICIYPAYLNNKKTIAEGRRIPINKAVENP
                     TATEIQDVCSAVGLNAFLEKNKMYSREWNRDVQYRGRVRVQLKQEDGSLCLVQFPSRK
                     SVMLYVAEMIPKLKTRTQKSGGADPSLQQGEGSKKGKGKKKK"
     exon            51..126
                     /gene="Srp19"
                     /inference="alignment:Splign:2.1.0"
     exon            127..198
                     /gene="Srp19"
                     /inference="alignment:Splign:2.1.0"
     exon            199..310
                     /gene="Srp19"
                     /inference="alignment:Splign:2.1.0"
     exon            311..760
                     /gene="Srp19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggtggaga tggcatgcgc tgccgcgcgg tccccggccg accaggacag gtttatttgt
       61 atctaccccg cttatttaaa taataagaag accatagctg aggggaggcg gatccccatt
      121 aataaggctg tagaaaaccc cacggctact gagattcagg atgtatgttc agcagttgga
      181 ctgaatgcgt ttctggagaa aaacaaaatg tactccagag aatggaatcg tgatgttcag
      241 tatagaggca gagttcgggt acagctcaaa caggaagatg gcagcctctg tcttgtacag
      301 ttcccatcac gtaagtcggt gatgctgtac gtagcagaaa tgatacccaa gctaaaaaca
      361 aggactcaga agtcaggagg tgctgaccca agtcttcagc agggagaggg gagtaagaaa
      421 gggaaaggaa agaagaagaa atgatgtggc gtgaacatac agtgtgcagt tctgctggga
      481 gagacgtggc atctttgcgt gtgagggaac agctttttgt tgtgttgttt aactgagctg
      541 cgaacgtgtg tctcccatct tcaacagtta acaatgaagt cagtttacat cacaagtttg
      601 catccagctt ttagatgtaa aaagaaaaat tgtgtgtgtg gaagaaagaa tatttttaac
      661 agataatgac tgtcccataa gttacttgaa atatctatct gtttgtcctc cgtgtaaaca
      721 tatttcagat atatatgttt aataaagttt ggaatacaca aaaaaaaaaa aaaaaaaaaa
      781 aaaa
//
