LOCUS       NM_001128190             827 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus sorcin (Sri), mRNA.
ACCESSION   NM_001128190
VERSION     NM_001128190.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 827)
  AUTHORS   Suarez J, McDonough PM, Scott BT, Suarez-Ramirez A, Wang H,
            Fricovsky ES and Dillmann WH.
  TITLE     Sorcin modulates mitochondrial Ca(2+) handling and reduces
            apoptosis in neonatal rat cardiac myocytes
  JOURNAL   Am J Physiol Cell Physiol 304 (3), C248-C256 (2013)
   PUBMED   23151801
  REMARK    GeneRIF: Sorcin prevented 2-deoxyglucose-induced cytochrome c
            release.
REFERENCE   2  (bases 1 to 827)
  AUTHORS   Ali R, Huang Y, Maher SE, Kim RW, Giordano FJ, Tellides G and
            Geirsson A.
  TITLE     miR-1 mediated suppression of Sorcin regulates myocardial
            contractility through modulation of Ca2+ signaling
  JOURNAL   J Mol Cell Cardiol 52 (5), 1027-1037 (2012)
   PUBMED   22326846
REFERENCE   3  (bases 1 to 827)
  AUTHORS   Noordeen NA, Meur G, Rutter GA and Leclerc I.
  TITLE     Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin
            and Ca(2+) ions in pancreatic beta-cells
  JOURNAL   Diabetes 61 (3), 574-585 (2012)
   PUBMED   22338092
REFERENCE   4  (bases 1 to 827)
  AUTHORS   Hu ST, Liu GS, Shen YF, Wang YL, Tang Y and Yang YJ.
  TITLE     Defective Ca(2+) handling proteins regulation during heart failure
  JOURNAL   Physiol Res 60 (1), 27-37 (2011)
   PUBMED   20945956
REFERENCE   5  (bases 1 to 827)
  AUTHORS   Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M and
            Stoorvogel W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   6  (bases 1 to 827)
  AUTHORS   Gracy KN, Clarke CL, Meyers MB and Pickel VM.
  TITLE     N-methyl-D-aspartate receptor 1 in the caudate-putamen nucleus:
            ultrastructural localization and co-expression with sorcin, a
            22,000 mol. wt calcium binding protein
  JOURNAL   Neuroscience 90 (1), 107-117 (1999)
   PUBMED   10188938
REFERENCE   7  (bases 1 to 827)
  AUTHORS   Meyers MB, Puri TS, Chien AJ, Gao T, Hsu PH, Hosey MM and Fishman
            GI.
  TITLE     Sorcin associates with the pore-forming subunit of
            voltage-dependent L-type Ca2+ channels
  JOURNAL   J Biol Chem 273 (30), 18930-18935 (1998)
   PUBMED   9668070
REFERENCE   8  (bases 1 to 827)
  AUTHORS   Pickel VM, Clarke CL and Meyers MB.
  TITLE     Ultrastructural localization of sorcin, a 22 kDa calcium binding
            protein, in the rat caudate-putamen nucleus: association with
            ryanodine receptors and intracellular calcium release
  JOURNAL   J Comp Neurol 386 (4), 625-634 (1997)
   PUBMED   9378856
REFERENCE   9  (bases 1 to 827)
  AUTHORS   Brownawell AM and Creutz CE.
  TITLE     Calcium-dependent binding of sorcin to the N-terminal domain of
            synexin (annexin VII)
  JOURNAL   J Biol Chem 272 (35), 22182-22190 (1997)
   PUBMED   9268363
REFERENCE   10 (bases 1 to 827)
  AUTHORS   Kohnoe,S., Maehara,Y. and Endo,H.
  TITLE     A systematic survey of repetitive sequences abundantly expressed in
            rat tumors
  JOURNAL   Biochim Biophys Acta 909 (2), 107-114 (1987)
   PUBMED   3593728
  REMARK    Erratum:[Biochim Biophys Acta 1987 Oct 9;910(1):93]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158845.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158845.1, FQ226061.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..827
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q12"
     gene            1..827
                     /gene="Sri"
                     /note="sorcin"
                     /db_xref="GeneID:683667"
                     /db_xref="RGD:1584485"
     exon            1..66
                     /gene="Sri"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..612
                     /gene="Sri"
                     /codon_start=1
                     /product="sorcin"
                     /protein_id="NP_001121662.1"
                     /db_xref="GeneID:683667"
                     /db_xref="RGD:1584485"
                     /translation="MSYPGHPGAGGGYYPGGCGGAPGGPVFPGHTQDPLYGYFAAVAG
                     QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFSEFRELWTVL
                     SGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQTVNSVAKRYSTSGKITFDDYI
                     ACCVKLRALTDSFRRRDSGQQGVVNFSYDDFIQCVMTV"
     exon            67..150
                     /gene="Sri"
                     /inference="alignment:Splign:2.1.0"
     exon            151..220
                     /gene="Sri"
                     /inference="alignment:Splign:2.1.0"
     exon            221..264
                     /gene="Sri"
                     /inference="alignment:Splign:2.1.0"
     exon            265..412
                     /gene="Sri"
                     /inference="alignment:Splign:2.1.0"
     exon            413..526
                     /gene="Sri"
                     /inference="alignment:Splign:2.1.0"
     exon            527..585
                     /gene="Sri"
                     /inference="alignment:Splign:2.1.0"
     exon            586..802
                     /gene="Sri"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgcagtct gcaccatgtc gtatcccggg caccctggcg ctggcggagg gtactaccca
       61 ggcgggtgtg gaggggctcc tggggggcct gtgttccctg gacacactca ggacccgctc
      121 tatggttact ttgctgctgt ggctggacag gacggacaaa ttgatgctga cgagttgcag
      181 cgatgcctaa ctcagtctgg catagcggga ggatacaaac cttttaacct ggagacttgt
      241 cgccttatgg tttcaatgct ggatagagat atgtctggca cgatggggtt cagtgagttc
      301 agagagctct ggactgtgct gagtggctgg agacaacact tcatcagctt cgacagtgat
      361 aggagtggga cagtggatcc ccaggagctg cagaaggccc taaccactat ggggttcagg
      421 ttgagccccc aaaccgtgaa ttcagtagca aagcggtaca gcaccagcgg gaagatcacc
      481 tttgatgact acatagcctg ctgtgtcaaa ctgagggctc tcacagatag cttccgcaga
      541 cgggattctg gtcaacaagg agttgtgaat ttctcgtacg atgatttcat ccagtgtgtc
      601 atgactgtct aactcaagag gccgctgtct gaatatattc aacattccaa ctggagccca
      661 cctattgctt cctcctgccc ttcagtgctg tgtgcagact ctgccgacac acgctccttg
      721 acaactgttg aatgggatta tgcctttatc tagaaccaag gcttcatttt taattttgat
      781 aataaattcc tttgaagttt aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
