LOCUS       XM_039105963            3985 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus SRC proto-oncogene, non-receptor
            tyrosine kinase (Src), transcript variant X11, mRNA.
ACCESSION   XM_039105963
VERSION     XM_039105963.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039105963.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3985
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3985
                     /gene="Src"
                     /note="SRC proto-oncogene, non-receptor tyrosine kinase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 46 ESTs, 4 long SRA reads, 17
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 23 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:83805"
                     /db_xref="RGD:620795"
     CDS             479..2107
                     /gene="Src"
                     /codon_start=1
                     /product="proto-oncogene tyrosine-protein kinase Src
                     isoform X1"
                     /protein_id="XP_038961891.1"
                     /db_xref="GeneID:83805"
                     /db_xref="RGD:620795"
                     /translation="MGSNKSKPKDASQRRRSLEPAENVHGAGGAFPASQTPSKPASAD
                     GHRGPNAAFVPPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETD
                     LSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFG
                     KITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDS
                     GGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESL
                     RLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQL
                     YAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYV
                     HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTI
                     KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCW
                     RKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL"
ORIGIN      
        1 gagctgtctg cttgctgtct gtaggcagtt tttaacctct ggagtccgag acgtcggttt
       61 gtcatttttc ttagggtgtc tttttgcagt tccagggaca ctggcttcat ggagtgaatt
      121 ggagaactgg ccttaactat ccctaagtat ctggcccgat ccatcactga agcctccccg
      181 tcatctggct gaggtcaaga gagttcacca gcgaagctgt ctgggcctgg gcctttttaa
      241 gggaagtttt aaaatgacta actcaaggcc tggagagatg aatcagtgag tctctgcaga
      301 tgcagatgca gatgttgaga cccagagaag gggagctgct cgcctaggga tacgtagcag
      361 gagaggagga gcagggcctt taagccaaga cccggacact acggctggtg tctgtgccaa
      421 gcccccagac tgctcccctg atccactggg gtagccctgc tacctaccag ccaggaccat
      481 gggcagcaac aagagcaagc ccaaggacgc cagccagagg cgccgcagcc tggagcccgc
      541 ggagaacgtg catggggcag gtggcgcctt ccctgcctca cagacaccaa gcaagcctgc
      601 ctccgccgat ggccaccgcg ggcccaatgc cgcctttgtg ccccccgcgg ccgccgagcc
      661 caagctcttc ggaggcttca actcctcgga cactgtcacc tccccacaaa gggcggggcc
      721 tctggcaggt ggggtgacta cctttgtggc cctctatgac tatgagtcac ggacagagac
      781 tgacctgtcc ttcaagaaag gggagcggct gcagattgtc aataacacga ggaaggtgga
      841 tgtcagagag ggagactggt ggctggcaca ctcgctgagc accggacaga ccggttacat
      901 ccccagtaac tatgtggcgc cctccgactc catccaggct gaggagtggt actttggcaa
      961 gatcactaga cgggaatcag agcggctact tctcaacgcc gagaacccca gagggacctt
     1021 cctcgtgagg gagagtgaga ccacaaaagg tgcctactgc ctctctgtat ccgactttga
     1081 caatgccaag ggcctaaatg tgaaacacta caagatccgg aaactggaca gtggcggatt
     1141 ctacatcacc tcccgcacgc aattcaacag cctgcagcag cttgtggctt actactccaa
     1201 acatgctgat ggcctgtgtc accgtctcac taccgtgtgt cccacatcca agcctcagac
     1261 ccagggcctg gccaaggatg cgtgggagat cccccgggag tccctgcggc tggaggtcaa
     1321 gctgggccag ggttgcttcg gagaggtgtg gatggggacc tggaacggca ccacgagggt
     1381 tgccatcaaa accctgaagc caggcaccat gtctccagag gccttcctgc aggaggccca
     1441 agtcatgaag aaactgaggc atgagaagct ggtgcagctg tatgccgtgg tgtcagaaga
     1501 acccatttac attgtgacag agtacatgaa caaggggagt ctgctggact ttctcaaggg
     1561 ggaaacgggc aaatacttgc ggctacccca gctggtggac atgtctgctc agattgcttc
     1621 aggcatggcc tatgtggagc ggatgaacta tgtgcaccgg gacctccgag ccgccaatat
     1681 cctggttggc gagaacctgg tgtgcaaagt ggccgacttt gggctggccc ggctcataga
     1741 ggacaacgaa tacacagctc ggcaaggtgc caaattcccc atcaagtgga ccgcccctga
     1801 agcggctctg tatggcaggt tcaccatcaa gtcggacgtg tggtcctttg gaatcctgct
     1861 gactgagctc accactaagg gcagagtgcc ctatcctggg atggtgaacc gagaggtgct
     1921 ggaccaggta gagcggggct accggatgcc ttgtcccccc gagtgccctg agtccctgca
     1981 tgacctcatg tgccagtgct ggcggaagga gcctgaggag cggcccacct tcgagtacct
     2041 gcaggccttc ctggaggact actttacgtc cacggagccg cagtaccagc ccggggagaa
     2101 cctataggaa ctgtgtgcac agaactgtca cctctaggct tttgggtgtc gcctcccttc
     2161 atcctctctc tggggctgag ttcctctgca atgccccttt tggagcatgg aagggcttca
     2221 gggacggggc agcctggaag gacaggttga ggctggtaca gcgactgtcc cacgcctgcc
     2281 atggccacag gctctctgtg cattctctct ggagtcggcc tgcttcatac tgggtgacga
     2341 gccgagctgg gggcggtttt ccaacctcaa cccactctac ccacctggct cctccccact
     2401 ttctaaaccc tgggtctgtt tcaagctggc caaagagcct ttccaaagag gaataaggcc
     2461 cagcccttgg cctatatgta ctaactgccc ctggtcatcc ttgttggagg cttctgggtg
     2521 gaacattggg tctagaaccc tctcccatgg ctctcaggct agacagccca agacccaaca
     2581 ccagttggga taagtgtcag agtgagcact ccctcagccc tgtcctcacc aaggaccctt
     2641 gagatcacca acacattacc ctcatttctc tgttggaaaa actgaatcca ggaggggctg
     2701 ggacctgtcc aagaccacgg gcagtttcgg gttgaggtgg gcttggcacc tggtgctccc
     2761 tctgtcttcc tcaggaacta acgagagctg tcctccaagg gagtgggcag gctgaggccc
     2821 gagagtggct tcaagttgtc agggttctgc tctcactgat gctcatgggt ctatcatggg
     2881 ggaagaggca agcaggaggc tgagcccggc gtgaggggta ggaaatgacg gtgtggaaga
     2941 ggtgcgtcac aatgcagctg ggctttgacc ttaagagctg gccgtgaagt ggagtgagcg
     3001 ctcaggctgc agaggcagtc aggtagaaga ggaagaacta agaagtgagg agccccgctc
     3061 ctcaatttgt cctgatcatt tcaacaccct gcgcatgctc ttctgcctat gctgggattc
     3121 cctaactcac agggagggag gggagctccc cggctgggga aaggagggag acgatcctta
     3181 ctgctatgca ccaacactga ccctgccctc tctaagctaa actctctgcc cctgtgactc
     3241 tggcttctgc cattgctcag cccctttata gatagatcca cagctgggtg accaagggga
     3301 gcacggccct ggaacagcag acagctgact gcttggtccc tggctcttct gcctagcctt
     3361 aggatatgtg gtagcttctc tctgcctcag tgtccctatc tgtaaggtgg gcagttggtg
     3421 atttgtggca tttcaaccaa ggacccctgt gtgtgtgtgt ctgtgtgtgt ctgtgtgtgt
     3481 gtgtacacat gtgcctgtgt cttcccttgt gtccatattt aacgtgtaaa aacatcccta
     3541 ctctgtcccc agacatggcc atttcacaat taccccatca cagcaataat gtccccagcg
     3601 ccggggatcc gagccagcca ggccctgctt gcagggaagg atgccaagca gggcctgccc
     3661 tgacatttcc acttcactcc catggtctcc tgcccaagtc tccccatgca cctggcgagt
     3721 ctaagcttgc cacccaattc tccctaccca actccaactg cccaaggacc tttgtgtaag
     3781 gtggcctcag cggtccggtt ttctcctttt ctttcttttt aacagtgttt tgtagatttc
     3841 ggatgactat gcagaggcct tggggacccc cagctctcgg cagggcctgg ggatcccaca
     3901 ttccatggcc caggtgtggg ggagggttac ccagactggt tgtacatact ctgcatactg
     3961 tctgattaaa cacgaacaga cctca
//
