LOCUS       XM_039105957            3934 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus SRC proto-oncogene, non-receptor
            tyrosine kinase (Src), transcript variant X1, mRNA.
ACCESSION   XM_039105957
VERSION     XM_039105957.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039105957.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3934
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3934
                     /gene="Src"
                     /note="SRC proto-oncogene, non-receptor tyrosine kinase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 48 ESTs, 4 long SRA reads, 17
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 85 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:83805"
                     /db_xref="RGD:620795"
     CDS             428..2056
                     /gene="Src"
                     /codon_start=1
                     /product="proto-oncogene tyrosine-protein kinase Src
                     isoform X1"
                     /protein_id="XP_038961885.1"
                     /db_xref="GeneID:83805"
                     /db_xref="RGD:620795"
                     /translation="MGSNKSKPKDASQRRRSLEPAENVHGAGGAFPASQTPSKPASAD
                     GHRGPNAAFVPPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETD
                     LSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFG
                     KITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDS
                     GGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESL
                     RLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQL
                     YAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYV
                     HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTI
                     KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCW
                     RKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL"
ORIGIN      
        1 gccaccgccg ccgccgcctc ctccctttct ctcggtctgt ctctcccggc ccggaatcca
       61 gccggccgcc ccgccggagc ggccaggccg ccgcccgcca gcgccgcgcg ccccgctggg
      121 gtccgcccgg gcgcgtccgg agctcgcggt cgccgcgcag gacagaatac agaggccaag
      181 agtgctgagt gacctgtgta accatgacag gccgagccgg gatctgaaca aaggcagagt
      241 ctctgcagat gcagatgcag atgttgagac ccagagaagg ggagctgctc gcctagggat
      301 acgtagcagg agaggaggag cagggccttt aagccaagac ccggacacta cggctggtgt
      361 ctgtgccaag cccccagact gctcccctga tccactgggg tagccctgct acctaccagc
      421 caggaccatg ggcagcaaca agagcaagcc caaggacgcc agccagaggc gccgcagcct
      481 ggagcccgcg gagaacgtgc atggggcagg tggcgccttc cctgcctcac agacaccaag
      541 caagcctgcc tccgccgatg gccaccgcgg gcccaatgcc gcctttgtgc cccccgcggc
      601 cgccgagccc aagctcttcg gaggcttcaa ctcctcggac actgtcacct ccccacaaag
      661 ggcggggcct ctggcaggtg gggtgactac ctttgtggcc ctctatgact atgagtcacg
      721 gacagagact gacctgtcct tcaagaaagg ggagcggctg cagattgtca ataacacgag
      781 gaaggtggat gtcagagagg gagactggtg gctggcacac tcgctgagca ccggacagac
      841 cggttacatc cccagtaact atgtggcgcc ctccgactcc atccaggctg aggagtggta
      901 ctttggcaag atcactagac gggaatcaga gcggctactt ctcaacgccg agaaccccag
      961 agggaccttc ctcgtgaggg agagtgagac cacaaaaggt gcctactgcc tctctgtatc
     1021 cgactttgac aatgccaagg gcctaaatgt gaaacactac aagatccgga aactggacag
     1081 tggcggattc tacatcacct cccgcacgca attcaacagc ctgcagcagc ttgtggctta
     1141 ctactccaaa catgctgatg gcctgtgtca ccgtctcact accgtgtgtc ccacatccaa
     1201 gcctcagacc cagggcctgg ccaaggatgc gtgggagatc ccccgggagt ccctgcggct
     1261 ggaggtcaag ctgggccagg gttgcttcgg agaggtgtgg atggggacct ggaacggcac
     1321 cacgagggtt gccatcaaaa ccctgaagcc aggcaccatg tctccagagg ccttcctgca
     1381 ggaggcccaa gtcatgaaga aactgaggca tgagaagctg gtgcagctgt atgccgtggt
     1441 gtcagaagaa cccatttaca ttgtgacaga gtacatgaac aaggggagtc tgctggactt
     1501 tctcaagggg gaaacgggca aatacttgcg gctaccccag ctggtggaca tgtctgctca
     1561 gattgcttca ggcatggcct atgtggagcg gatgaactat gtgcaccggg acctccgagc
     1621 cgccaatatc ctggttggcg agaacctggt gtgcaaagtg gccgactttg ggctggcccg
     1681 gctcatagag gacaacgaat acacagctcg gcaaggtgcc aaattcccca tcaagtggac
     1741 cgcccctgaa gcggctctgt atggcaggtt caccatcaag tcggacgtgt ggtcctttgg
     1801 aatcctgctg actgagctca ccactaaggg cagagtgccc tatcctggga tggtgaaccg
     1861 agaggtgctg gaccaggtag agcggggcta ccggatgcct tgtccccccg agtgccctga
     1921 gtccctgcat gacctcatgt gccagtgctg gcggaaggag cctgaggagc ggcccacctt
     1981 cgagtacctg caggccttcc tggaggacta ctttacgtcc acggagccgc agtaccagcc
     2041 cggggagaac ctataggaac tgtgtgcaca gaactgtcac ctctaggctt ttgggtgtcg
     2101 cctcccttca tcctctctct ggggctgagt tcctctgcaa tgcccctttt ggagcatgga
     2161 agggcttcag ggacggggca gcctggaagg acaggttgag gctggtacag cgactgtccc
     2221 acgcctgcca tggccacagg ctctctgtgc attctctctg gagtcggcct gcttcatact
     2281 gggtgacgag ccgagctggg ggcggttttc caacctcaac ccactctacc cacctggctc
     2341 ctccccactt tctaaaccct gggtctgttt caagctggcc aaagagcctt tccaaagagg
     2401 aataaggccc agcccttggc ctatatgtac taactgcccc tggtcatcct tgttggaggc
     2461 ttctgggtgg aacattgggt ctagaaccct ctcccatggc tctcaggcta gacagcccaa
     2521 gacccaacac cagttgggat aagtgtcaga gtgagcactc cctcagccct gtcctcacca
     2581 aggacccttg agatcaccaa cacattaccc tcatttctct gttggaaaaa ctgaatccag
     2641 gaggggctgg gacctgtcca agaccacggg cagtttcggg ttgaggtggg cttggcacct
     2701 ggtgctccct ctgtcttcct caggaactaa cgagagctgt cctccaaggg agtgggcagg
     2761 ctgaggcccg agagtggctt caagttgtca gggttctgct ctcactgatg ctcatgggtc
     2821 tatcatgggg gaagaggcaa gcaggaggct gagcccggcg tgaggggtag gaaatgacgg
     2881 tgtggaagag gtgcgtcaca atgcagctgg gctttgacct taagagctgg ccgtgaagtg
     2941 gagtgagcgc tcaggctgca gaggcagtca ggtagaagag gaagaactaa gaagtgagga
     3001 gccccgctcc tcaatttgtc ctgatcattt caacaccctg cgcatgctct tctgcctatg
     3061 ctgggattcc ctaactcaca gggagggagg ggagctcccc ggctggggaa aggagggaga
     3121 cgatccttac tgctatgcac caacactgac cctgccctct ctaagctaaa ctctctgccc
     3181 ctgtgactct ggcttctgcc attgctcagc ccctttatag atagatccac agctgggtga
     3241 ccaaggggag cacggccctg gaacagcaga cagctgactg cttggtccct ggctcttctg
     3301 cctagcctta ggatatgtgg tagcttctct ctgcctcagt gtccctatct gtaaggtggg
     3361 cagttggtga tttgtggcat ttcaaccaag gacccctgtg tgtgtgtgtc tgtgtgtgtc
     3421 tgtgtgtgtg tgtacacatg tgcctgtgtc ttcccttgtg tccatattta acgtgtaaaa
     3481 acatccctac tctgtcccca gacatggcca tttcacaatt accccatcac agcaataatg
     3541 tccccagcgc cggggatccg agccagccag gccctgcttg cagggaagga tgccaagcag
     3601 ggcctgccct gacatttcca cttcactccc atggtctcct gcccaagtct ccccatgcac
     3661 ctggcgagtc taagcttgcc acccaattct ccctacccaa ctccaactgc ccaaggacct
     3721 ttgtgtaagg tggcctcagc ggtccggttt tctccttttc tttcttttta acagtgtttt
     3781 gtagatttcg gatgactatg cagaggcctt ggggaccccc agctctcggc agggcctggg
     3841 gatcccacat tccatggccc aggtgtgggg gagggttacc cagactggtt gtacatactc
     3901 tgcatactgt ctgattaaac acgaacagac ctca
//
