LOCUS       NM_001106849            2802 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus splA/ryanodine receptor domain and SOCS box
            containing 4 (Spsb4), mRNA.
ACCESSION   NM_001106849 XM_001069568 XM_236555
VERSION     NM_001106849.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2802)
  AUTHORS   Okumura F, Joo-Okumura A, Obara K, Petersen A, Nishikimi A, Fukui
            Y, Nakatsukasa K and Kamura T.
  TITLE     Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated
            by EphB2
  JOURNAL   Mol Biol Cell 28 (24), 3532-3541 (2017)
   PUBMED   28931592
REFERENCE   2  (bases 1 to 2802)
  AUTHORS   DeBruyne JP, Baggs JE, Sato TK and Hogenesch JB.
  TITLE     Ubiquitin ligase Siah2 regulates RevErbalpha degradation and the
            mammalian circadian clock
  JOURNAL   Proc Natl Acad Sci U S A 112 (40), 12420-12425 (2015)
   PUBMED   26392558
REFERENCE   3  (bases 1 to 2802)
  AUTHORS   Nishiya T, Matsumoto K, Maekawa S, Kajita E, Horinouchi T, Fujimuro
            M, Ogasawara K, Uehara T and Miwa S.
  TITLE     Regulation of inducible nitric-oxide synthase by the SPRY domain-
            and SOCS box-containing proteins
  JOURNAL   J Biol Chem 286 (11), 9009-9019 (2011)
   PUBMED   21199876
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC168912.1.
            
            On Sep 4, 2008 this sequence version replaced NM_001106849.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168912.1, SRR8487226.73591.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN11044071, SAMN12840111
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2802
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..2802
                     /gene="Spsb4"
                     /gene_synonym="RGD1562307"
                     /note="splA/ryanodine receptor domain and SOCS box
                     containing 4"
                     /db_xref="GeneID:300950"
                     /db_xref="RGD:1562307"
     exon            1..555
                     /gene="Spsb4"
                     /gene_synonym="RGD1562307"
                     /inference="alignment:Splign:2.1.0"
     exon            556..1402
                     /gene="Spsb4"
                     /gene_synonym="RGD1562307"
                     /inference="alignment:Splign:2.1.0"
     CDS             709..1530
                     /gene="Spsb4"
                     /gene_synonym="RGD1562307"
                     /codon_start=1
                     /product="SPRY domain-containing SOCS box protein 4"
                     /protein_id="NP_001100319.1"
                     /db_xref="GeneID:300950"
                     /db_xref="RGD:1562307"
                     /translation="MGQKLSGSLKSVEVREPALRPAKRELRGLEPGRPARLDQLLDMP
                     AAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQI
                     HWPARQRGTHAVVGVATARAPLHSVGYTALVGSDSESWGWDLGRSRLYHDGKNRPGVA
                     YPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWG
                     HCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLRDIGSLPLPQSLKNYLQYQ"
     exon            1403..2775
                     /gene="Spsb4"
                     /gene_synonym="RGD1562307"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggccctggcg gtcggcgcgc cccgcgcaca aaggcgccca gcccctgggg aaggcaatga
       61 gcgcacagca gcccgggccc tggccaccgc tgcagccctc caggcgtgtg ctcggtgctc
      121 tggggaagaa accgggtgct ccggggacga gcggccgagg tgaggcccga gtgccctgag
      181 tgcgagattc gtcgccctcc aggtcaggcg ccaagcttta gggccaccag ggcaagggct
      241 tccgcgcccc tctgagatca gcgtagtcgg gcacttcacc actcgggact ggacctcggc
      301 ggccactcgc ctctcctgag cgtcaacttc tccaagaacg tccctaactc cagggcaccc
      361 tgcggagaga gagggcgctg ccgccgggta caactgagag gacgcgtcgc tgactgagaa
      421 gcagcagcca gcatccgcgg ggtcgctcgg gcgcccctga gtgggcggca gtggcagcag
      481 acctctctcc cgggagtccc ggacctgcca gcgctgggga ttcctcccag gcgggcgctc
      541 gtcttctctt ttatggagct tgggcccttg ccacagccca gcagaggctg tagagaacaa
      601 ccgtcagaaa gtctggttcc cagccccagg gtccatccct ggataccagg agtggaagct
      661 tctgcgaggt agcagtggcc agcagcggtc ccctccccat agtgaaccat gggtcagaag
      721 ctctctggga gcctcaagtc tgtggaggtg cgagagccag cgcttcggcc agccaagcgg
      781 gagctccgag gcttagagcc tgggcggcca gcacggctag accagctgct agacatgcct
      841 gcagcgggct tggctgtaca gctgagacac gcgtggaacc ctgaggaccg atccctcaat
      901 gtcttcgtaa aggatgacga ccgcctcacc ttccaccgac acccggtagc ccagagcaca
      961 gatggcatcc gaggcaaggt tggccatgcc cggggtctgc atgcatggca gatccattgg
     1021 ccagctaggc agcggggtac ccacgctgtg gtgggcgtgg ccacagcccg tgcccctttg
     1081 cactctgtgg gttacaccgc actggtaggc agtgactccg agtcgtgggg ctgggacctg
     1141 ggtcgtagcc gcctctacca cgacggcaag aaccggcctg gggtggcata ccctgccttc
     1201 ctggggccag atgaggcctt tgctctgccg gattccttat tggttgtatt ggacatggat
     1261 gagggcacgc tcagcttcat cgtggatggc cagtacttgg gcgtggcatt ccgtggcctc
     1321 aagggcaaga aactataccc ggtggtgagt gctgtatggg gtcactgcga agtcaccatg
     1381 cgctacatca atggccttga ccctgagcct ctgccgttga tggacctatg ccggcgatcc
     1441 atccgctcag ccctgggcag acagcgcctg cgggacatcg gctccctgcc cctgcctcag
     1501 tctcttaaaa actatctgca gtaccaatga gcagtgctga ggacctgctg tcacctgtgg
     1561 tcacacagct ccggagcatt gggatgacat cactgatttg ctgccatcaa ccaggaccag
     1621 gaggccacca agggaaccag agtgtagaga ccatttcttc ctccagagaa tgaataaaac
     1681 attcagtagg agatggcgtc cggttcccca ctgcagacgg ctcaggaaga ttggccagtg
     1741 gagagaaaat aggttctgaa taatgaacga cgaagtcagg ccttcacgct ctcctccccg
     1801 cctgcccctg gccagggcag agagaccatc cttccatatt aagactcagt accactttga
     1861 gagacgggtc cagggcccat agcagggcta aaacgcctgg ccttacctct ctgagcttgg
     1921 cttcctcatc ccttcctgcc ctcttgcccc atggatagag ttctttggct accccccacc
     1981 cctctattca gggacacgaa tctgatgact tgccccgggg acagagctta ttcttggcta
     2041 tgttcattgt cagtagtgtt tgcattttga aagaggagtg tggcaaaggt ggctttctcc
     2101 caaaggtgct aaggaagagg ggagcctcgt gacaccaagt ctgagacacc ctgagtaccc
     2161 agggctctgg tggccatcat cagggtgaag cctggctgtc acaaagcttt ctctgagcaa
     2221 attatttttt cactgcagga gacttccagt ttgtctctcg tttccagcgc acgtgtgtgt
     2281 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtacatgtat gtgtatgtat
     2341 gtgtgtgttg gtgtgtgtat gtgtatacat gtgtgtgtat gtatatgtgt gtgtgttggt
     2401 gtgtatatgt gtgtgtgtac gtgtgtgtgt gtacgtgtgt gtgtgtgtgt gtgtggcgct
     2461 gtttatttat cagctggggc cccgtggggt ggccttggga ctgcaaagtg tctctgcagt
     2521 ctctgcagga cctgagacct atcctctcac agaatgctgc tgctgctgct gctgctgccg
     2581 ctgctgctac tgccaccagc gccaccattt gacatctttc gtgtgttcca gataccctcc
     2641 acccagactc ggttttaact ggaaatcgtc acagagtggg atacaaagcc agacagcagc
     2701 gcagcctaca ctttaatgtg aatgtgacct acaagcaagg gacatttcta ataaagtttg
     2761 tcattctgtc cttgaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
