LOCUS       NM_001415863            4132 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus sprouty-related, EVH1 domain containing 3
            (Spred3), transcript variant 1, mRNA.
ACCESSION   NM_001415863 XM_008759144
VERSION     NM_001415863.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4132)
  AUTHORS   Kato,R., Nonami,A., Taketomi,T., Wakioka,T., Kuroiwa,A., Matsuda,Y.
            and Yoshimura,A.
  TITLE     Molecular cloning of mammalian Spred-3 which suppresses tyrosine
            kinase-mediated Erk activation
  JOURNAL   Biochem Biophys Res Commun 302 (4), 767-772 (2003)
   PUBMED   12646235
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 4, 2023 this sequence version replaced XM_008759144.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1951634.1,
                                           SRR26360190.840368.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               JAXUCZ010000001.1  93597115-93597242   c
            129-309             JAXUCZ010000001.1  93595488-93595668   c
            310-478             JAXUCZ010000001.1  93594235-93594403   c
            479-555             JAXUCZ010000001.1  93594068-93594144   c
            556-696             JAXUCZ010000001.1  93590375-93590515   c
            697-4132            JAXUCZ010000001.1  93586259-93589694   c
FEATURES             Location/Qualifiers
     source          1..4132
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..4132
                     /gene="Spred3"
                     /gene_synonym="RGD1311713"
                     /note="sprouty-related, EVH1 domain containing 3"
                     /db_xref="GeneID:308478"
                     /db_xref="RGD:1311713"
     exon            1..128
                     /gene="Spred3"
                     /gene_synonym="RGD1311713"
                     /inference="alignment:Splign:2.1.0"
     exon            129..309
                     /gene="Spred3"
                     /gene_synonym="RGD1311713"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..1365
                     /gene="Spred3"
                     /gene_synonym="RGD1311713"
                     /codon_start=1
                     /product="sprouty-related, EVH1 domain-containing protein
                     3"
                     /protein_id="NP_001402792.1"
                     /db_xref="GeneID:308478"
                     /db_xref="RGD:1311713"
                     /translation="MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGAR
                     QGHYVIHGERLRDQKTTLECTLRPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEF
                     QKSLQAALAALSRGSLTPSSSSSSSSPSRDTAETPCPLTSHVDSDSSSSHSRQETPPT
                     AVAPIATVESATAFPPATPPQRRRSSAQSYPPLLPFTGIPEPSESLAGAGSQGRGGRG
                     YEDYRRSGPPPPPLALSTCVVRFAKTGALRGAALGPPVSLPAPLTEAAPPALPARPPP
                     GPGPTPAPAKASPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWC
                     AESLLYHCLSDAEGDFSDPCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRACHWV
                     AARCGCAGCGGRHEEAAR"
     exon            310..478
                     /gene="Spred3"
                     /gene_synonym="RGD1311713"
                     /inference="alignment:Splign:2.1.0"
     exon            479..555
                     /gene="Spred3"
                     /gene_synonym="RGD1311713"
                     /inference="alignment:Splign:2.1.0"
     exon            556..696
                     /gene="Spred3"
                     /gene_synonym="RGD1311713"
                     /inference="alignment:Splign:2.1.0"
     exon            697..4132
                     /gene="Spred3"
                     /gene_synonym="RGD1311713"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcccccctcg ccccggctcc cggtgcccgt ctccagcgcc gccggagcca gccagggagc
       61 gggagcgaac aggaggagga ggaggaggcc gcgtcgccgc cgctcggagc ccggccggag
      121 cctcccaggt acatggtgcg ggtccgagcc gtggtgatgg cccgagatga ctccagtggg
      181 ggctggctgc ctgtgggggg cgggggcctc agccaggtga gcgtatgtcg ggtccgaggg
      241 gccaggcccg aggggggggc ccgccagggg cactacgtca tccacgggga gcggcttcgg
      301 gaccagaaaa ccaccttgga gtgtaccctg aggccaggtt tggtttacaa caaagtgaac
      361 cctatcttcc accattggag cctgggggac tgcaagtttg ggctgacgtt tcagagtcct
      421 gcggaagccg atgagttcca gaagagcctg caggctgcac tggctgcgct gagtcgaggc
      481 tcgctgactc cctcctcctc ttcttcctcc tcctcccctt cccgagatac tgcagagact
      541 ccctgccctc tgacgtccca cgtggacagc gactcctcct ccagtcacag ccgccaggag
      601 actccaccca cagctgtcgc tcccattgcc acagtggagt cagcaactgc cttcccaccg
      661 gccacgcccc cacaaaggcg ccgctcctct gctcagagct accctccgct tctaccgttc
      721 actgggattc cagaaccttc cgagtctcta gctggggcag ggagccaggg caggggcggc
      781 cgtggctatg aggactaccg gcgatctgga ccaccgcctc cacctcttgc cctgtctacc
      841 tgcgttgtgc gctttgccaa gactggtgca ttgaggggtg cagccctggg tcccccagtg
      901 tcactccctg cccctctcac agaggctgca cccccagcac tccctgctcg tccaccccca
      961 ggcccaggcc ctacccctgc tccagccaaa gcctccccgg aggctgagga ggctgcgcgc
     1021 tgtgtgcact gccgagcact cttccgccgc cgggcagatg ggcgtggtgg tcgctgcgca
     1081 gaggcccccg acccaggtcg cctgctagtg cgcaggctca gctgcctgtg gtgcgctgag
     1141 agcttgttgt accactgcct gtcggacgcc gagggtgact tctccgaccc gtgtgcttgt
     1201 gagccaggcc acccgcgccc tgctgcgcgt tgggctgctc tggctgctct gtccctggca
     1261 gtgccctgcc tctgttgcta tgcgcccctg cgcgcctgtc actgggttgc agcacggtgt
     1321 ggctgtgcgg gctgtggggg tcgccacgag gaggctgcac ggtgaggatt gttgggctgg
     1381 tttggaaaat cggtctgaaa acccaaaatt tgaaggcctg ggaccctgaa ctccatatga
     1441 acctaaaacc caaacttagg tacaactgga acttgaatgg ctttgagaga tcccggatct
     1501 ggtacctgga ccccaaactg aggactgaga tccccagacc cagcttcatc agggtgtctg
     1561 tccacccgaa atcctgaatt ctggattctc cctccctctt ccccactgag gaaacttagg
     1621 agacttagga catctcaaac gttgcatctc aaggggccca ggagctcaca tccctgagac
     1681 ccggggatct tggaccctga ctttgtctaa atgcccaacc cagacttcag gtcgtttctt
     1741 gacattgtaa acactcatat tacggtcccc caaattagtc acgagttgct aaaacttgac
     1801 cctatataaa atgacttaga ccttgagacc agagaccgaa aatcaccaga aattggtccc
     1861 tgaattttca cctgagaccc ggtatctgca catttggctg ctcttataac cccaggacct
     1921 ggagacacca aaccctcctg ggtaagagac accagggggg tttggaatca ccagatactg
     1981 acctgaagtt tacccactcc tacaagtcca gacattgccg tcagttcatg tgcaagtgac
     2041 ccacaaattc cctagcaccc cagatttaaa atgcattaac tccttagata tcctcagatg
     2101 aggtattttc tgaccaaaat gacttggggt gcccttttca gagctcatca aggtccagat
     2161 atcagatacc aagatgctgg ggagccaggg accaaacacc tacccctcat gggtgggctc
     2221 taggtacctg gtacccttaa gtatatggct gaaggccagt agcattttgg gcccaacaca
     2281 ctggtttgta gagattagct aaccttccat tttctcttag gcctgaattt taagaccccg
     2341 tatattctga aaacatcggc ttccttctgt ctacattccc cattcaccaa gttgggtggg
     2401 agcctggaac ttagaagatg tggtggtcat ggtaacccag gtccttcagc ccttgactct
     2461 cagccctaga gcaaatctaa ggtgctttaa gagcactgga tctaagaccc cgagatatca
     2521 ctgggctcta ggtgcaggag tcaagttccc cacaatcttg ggattggctt tggctggtca
     2581 ccttggtccc ttcataccag agacattaag caacaagatg ctccaggatt ccagcacctt
     2641 tgggctccag atgttcttga attcaaagca cttctagact aatgaagccc ccatacctca
     2701 ccacctcatg ccccccaccc ctgtgtcctg ccatccagag gcccatgaaa ttggaatgtc
     2761 ccagcaatgc ccagattccc acccattccc cctttttcct agggcggggc acttgtgcca
     2821 gtgtaaattc agattcctgg aatctgggac cacacagctg tttccttttc ccttctctag
     2881 ggcctggctt tgccatggag gattgattgt acgtgggctg tcagctcagt aaaggcaggc
     2941 agctgcaggg gtcaagcaga agtagcagag aaggcctacc ctttgcacac cagtacttct
     3001 ggggccagca attgctccac agaagccccc ctctggccct catccctaac ctggcagatt
     3061 tcccacacca taacccctag tacattcagg tcccctctcc cgtgaatctt ttccatctca
     3121 gttgggagtc gctctggaaa gatcagtatt gttttgggta cttccccacg gaaaagagag
     3181 gtgccacagc ctctctaccc taagtagaga cactaggttc tgctgtcctg gataggagaa
     3241 ccaaggtttc agagccaata cagtctcaat ggttcatggg cttaggaccc atatctggcc
     3301 ctaagcacct gggaatgtgc acttgaacca ttcttcatta cccagacttg ggtggccttg
     3361 tagggattca agggattaat atttgtgtca cttcctttaa cttattaact atttattgta
     3421 tccggaacct gtgattcagc tccctgaagc agaccctggg atgggtgaga gaaaatggga
     3481 agaagggggt gttcttccca tccccattct tcccagttct catcaatgtc agacccacca
     3541 gagctgaggg cggagggact gggggctggg gcagcctggg tccccatccc ttctttgtgc
     3601 ctcggtctcc ccccttccat ggtaagcggg ggaagctcca ttcttaacct acctcgtttt
     3661 gggaaggggt ggggaggggg accagagtgc tgtatggtgc tgtgagatct tcagattaag
     3721 cagtggggac ttggggaagg ttccctagtc ccccatctcc cagtaccccc tctcccaggt
     3781 cccccagccc tgttccttgt cgatacccac ctctgatcca tgattacctt ccattgcccc
     3841 catatctggg gtgcatagag gactgaactc tgggggccag gaagtcctca gatcctggag
     3901 ctcctgaccc caattttcca gctgcttgcc cctcagattg gatgcttgcc ccccagattt
     3961 tgggggaggt atgccaacat ttatcttcct gatcttgatt cccagccagt ttgtgacttt
     4021 gtcagtggca gggcaggctg aagtggaagg aggatggggg ggccaaagat ccagccttgt
     4081 cattggggga ggggggcttg agatctgctc caagaaatgt ctgtgaccgt gt
//
