LOCUS       NM_001002816             554 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus serine peptidase inhibitor, Kazal type 7
            (Spink7), mRNA.
ACCESSION   NM_001002816 XM_579086
VERSION     NM_001002816.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 554)
  AUTHORS   Puente,X.S. and Lopez-Otin,C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
REFERENCE   2  (bases 1 to 554)
  AUTHORS   Cui,Y., Wang,J., Zhang,X., Lang,R., Bi,M., Guo,L. and Lu,S.H.
  TITLE     ECRG2, a novel candidate of tumor suppressor gene in the esophageal
            carcinoma, interacts directly with metallothionein 2A and links to
            apoptosis
  JOURNAL   Biochem Biophys Res Commun 302 (4), 904-915 (2003)
   PUBMED   12646258
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Oct 25, 2022 this sequence version replaced NM_001002816.2.
            
            Sequence Note:.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               JAXUCZ010000018.1  58319942-58320067   c
            127-152             JAXUCZ010000018.1  58319041-58319066   c
            153-277             JAXUCZ010000018.1  58318009-58318133   c
            278-554             JAXUCZ010000018.1  58316302-58316578   c
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..554
                     /gene="Spink7"
                     /gene_synonym="Ecg2; Ecrg2"
                     /note="serine peptidase inhibitor, Kazal type 7"
                     /db_xref="GeneID:408237"
                     /db_xref="RGD:1303077"
     exon            1..126
                     /gene="Spink7"
                     /gene_synonym="Ecg2; Ecrg2"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..323
                     /gene="Spink7"
                     /gene_synonym="Ecg2; Ecrg2"
                     /note="serine protease inhibitor Kazal-type 7; serine
                     peptidase inhibitor, Kazal type 7 (putative); ECRG-2;
                     esophagus cancer-related gene 2 protein; esophagus
                     cancer-related protein 2"
                     /codon_start=1
                     /product="serine protease inhibitor Kazal-type 7
                     precursor"
                     /protein_id="NP_001002816.2"
                     /db_xref="GeneID:408237"
                     /db_xref="RGD:1303077"
                     /translation="MKLLGGLLLLFTATCLCNSFSEVTSHPSPTVDCDIYKKYPVVAI
                     PCPIENIPVCGSDYITYGNKCKLCTEILRSNGKIQFLHEGHC"
     exon            127..152
                     /gene="Spink7"
                     /gene_synonym="Ecg2; Ecrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            153..277
                     /gene="Spink7"
                     /gene_synonym="Ecg2; Ecrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            278..554
                     /gene="Spink7"
                     /gene_synonym="Ecg2; Ecrg2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggacattcg ccttcaagcc aatctgagat cacttagcct ccacaccata gccctctcca
       61 ccatgaagct ccttggtggt ctcctgctgc tcttcacagc aacctgtttg tgcaacagct
      121 tctccgaagt taccagccac ccttcaccca cagtggactg tgacatatac aagaagtacc
      181 cagtagtggc catcccttgc cccattgaaa acatcccagt ttgtggatct gactatatca
      241 cttacgggaa taaatgcaag ttgtgtacag agatcttgag aagtaatggg aaaattcagt
      301 ttcttcatga agggcactgc taacttctcc atggacaaag aaagaacagt gaagccttca
      361 tcatgtgcct cacacgtggg ctctgatcga ctgcccttct ttgctgatgt tctggtggcg
      421 tcagatctag attcagtcac tgtcggtgac tgtggatagt ccttgtgctc attcctatca
      481 actcctgtct cctgatatat tacctttttt ggcacctgaa ttaaaaaaaa atctctccaa
      541 aaagtttact ttta
//
