LOCUS       NM_001191601            2956 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus signal peptidase complex subunit 2 (Spcs2), mRNA.
ACCESSION   NM_001191601 XM_214994
VERSION     NM_001191601.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2956)
  AUTHORS   Kalies,K.U. and Hartmann,E.
  TITLE     Membrane topology of the 12- and the 25-kDa subunits of the
            mammalian signal peptidase complex
  JOURNAL   J Biol Chem 271 (7), 3925-3929 (1996)
   PUBMED   8632014
REFERENCE   2  (bases 1 to 2956)
  AUTHORS   Shelness,G.S., Lin,L. and Nicchitta,C.V.
  TITLE     Membrane topology and biogenesis of eukaryotic signal peptidase
  JOURNAL   J Biol Chem 268 (7), 5201-5208 (1993)
   PUBMED   8444896
REFERENCE   3  (bases 1 to 2956)
  AUTHORS   Evans,E.A., Gilmore,R. and Blobel,G.
  TITLE     Purification of microsomal signal peptidase as a complex
  JOURNAL   Proc Natl Acad Sci U S A 83 (3), 581-585 (1986)
   PUBMED   3511473
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jul 17, 2010 this sequence version replaced XM_214994.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214686.1, CK365766.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676785, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-119               JAXUCZ010000001.1  163595151-163595269 c
            120-203             JAXUCZ010000001.1  163585296-163585379 c
            204-364             JAXUCZ010000001.1  163584640-163584800 c
            365-499             JAXUCZ010000001.1  163580996-163581130 c
            500-2956            JAXUCZ010000001.1  163575842-163578298 c
FEATURES             Location/Qualifiers
     source          1..2956
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..2956
                     /gene="Spcs2"
                     /gene_synonym="RGD1311253"
                     /note="signal peptidase complex subunit 2"
                     /db_xref="GeneID:293142"
                     /db_xref="RGD:1311253"
     exon            1..119
                     /gene="Spcs2"
                     /gene_synonym="RGD1311253"
                     /inference="alignment:Splign:2.1.0"
     CDS             6..686
                     /gene="Spcs2"
                     /gene_synonym="RGD1311253"
                     /codon_start=1
                     /product="signal peptidase complex subunit 2"
                     /protein_id="NP_001178530.1"
                     /db_xref="GeneID:293142"
                     /db_xref="RGD:1311253"
                     /translation="MAAAASQGGRSGGGGGSSGPGGGPSCGTSSSRSGLLDKWKIDDK
                     PVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWD
                     YMHPFPESKPVLALCVVSYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLS
                     SSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDS
                     LATERKIK"
     exon            120..203
                     /gene="Spcs2"
                     /gene_synonym="RGD1311253"
                     /inference="alignment:Splign:2.1.0"
     exon            204..364
                     /gene="Spcs2"
                     /gene_synonym="RGD1311253"
                     /inference="alignment:Splign:2.1.0"
     exon            365..499
                     /gene="Spcs2"
                     /gene_synonym="RGD1311253"
                     /inference="alignment:Splign:2.1.0"
     exon            500..2956
                     /gene="Spcs2"
                     /gene_synonym="RGD1311253"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaagatggc ggcggcggcg tcgcaaggcg ggagaagcgg cggcggcgga ggcagtagtg
       61 ggcctggcgg cggccccagc tgcgggacaa gcagtagccg cagtggtttg ttggataagt
      121 ggaagattga tgataagccc gtgaaaattg ataagtggga tggatcagct gtgaaaaact
      181 ctctggatga ttctgccaaa aaggttctcc tggagaagta caagtatgtg gagaacttcg
      241 gtctcattga cggtcgcctc accatctgca ccatctcctg cttcttcgcc atagtggctt
      301 tgatctggga ctacatgcat ccctttccag agtccaagcc ggttttggcc ttgtgcgtcg
      361 tatcctattt tgtgatgatg gggattctga ccatttatac ctcatataaa gagaagagca
      421 tcttcctcgt ggcccacaga aaagacccta caggaatgga tcctgatgat atttggcagc
      481 tgtcctccag cctcaaaagg tttgatgaca aatacaccct gaagttgacc ttcatcagtg
      541 gaaggacaaa gcagcagcgg gaagccgagt tcaccaagtc cattgctaag ttctttgacc
      601 acagcgggac attggtcatg gatgcatacg aacctgaaat atccaggctc catgacagtc
      661 tcgccacaga aagaaaaata aaatagccaa ttctaaaagt tctccttctg ctggatcata
      721 cgaattactg gtgggtaggg gaaaagacag gaagcttaag cttggtcaag taagaaatgt
      781 taaagatgcc cctgtttagt ccaccctgga taaatagaat ttcctagtac agatatgcaa
      841 agttgtatct ttgatggcta gctgtagcct ccttggtctg ctgaatggtt ttctgttgtt
      901 ttccttaaga agcctttttg taaaagctaa gcataccttt tcctttgtgc ttaatagtac
      961 tttatacagt atagctttgt gccatgcaat gtttgaatgc tcaattctca agaacgagcc
     1021 ttgctggggt gaggtagtgt tcacctgtaa tcccagcact cggagggctg aggaagggga
     1081 ttcagttgga ggccgtcctg ggctgtagag ctaggcccat cttgaagagt gggtattgtt
     1141 aacttgttgc tgactttgta ttgacccctg catcagcaac tatttcctta aatccaggat
     1201 acaacttctt aagtatgaca gctttccttt acacaccatt tttgtgggtg tatatatata
     1261 tttgacttgg ggagaattat tttttaaaaa aatacaaaat agctttttaa tttgtttaaa
     1321 atagacctgc ctgttacatt ttgtgctctt aaccaattaa agaagccagt ggcattttta
     1381 gttttatatt ctctgttccc actcgtacgt tcctgttgat ttgtgtgtgc cctttattaa
     1441 ctgccatttt ctaaagtttt tttcaataaa tgaaagaaga tgtgaaaata tagagtacta
     1501 gtcttggaag gaggaacagc accgcaaatg ctttactcgg atggagtccc ttctgggctg
     1561 actcactctc ggcaggctgg tgagaacccg gagccaggga ctcttagttc tagtgatagc
     1621 agcagagaca ctttactctg ggcatgtcac tggcttactg aagctcactc acagctgtcc
     1681 taagggcagg cactgttgtg tgcacacacg cacggcatgc acactcacgc gcgcgcgcgc
     1741 gcacacacac acacacacat gcatgcacga agagcctaag acatgaaagt aaacagttca
     1801 cagatggttc tagaatagga acttaagttt gaggaatctg gctccagatg ttatgttcct
     1861 gcacagccaa aaataaaaaa taatgagtta atatcttttc cagtattttc tcaatttggt
     1921 cagagaactg gacacttgca ggatctaatt ctaagtctag taccccaaat tacattccca
     1981 ataagaagca tccaaagaac attgggaatg ttgtcctgtc tagcactacc cagtgagacc
     2041 acactggcca gatgctgaag ccgtgggttc cctaagcctt cctgtaatcc ttcggtaagt
     2101 cagagttcct tgaacttcta atgctgcccc cacccattct tataaaagta ccagtgcagg
     2161 gcttgtttaa taaagtgctc accatgcaag cataggagcc tgagtttggc ctttagggtg
     2221 catgtaaaga gaggccaggt agcacggttg ttatcccagt gctgatgaag cagatacgag
     2281 atgatttcta gcatgctgcc tggccagcct aaacaccagg gctggggaga tgaccagatg
     2341 ggtaaaatgc ttgctgtgta aaaatcccca gaacccacat aggagacatg aatggtaaag
     2401 cacatctaac ccttgtgtcg caggaacaca aggcagaggc tagggtcttg ctggccagcc
     2461 agactggctg aaatagcaag ctgcaggggc agcaaaaggc ctggctcaaa agtcagggtg
     2521 catagaaatg gaggaagact tgtgctgtca accacgggcc tccacaggta catagaccaa
     2581 tactctaagt cagcccctac ctctctgcct gggcacacag ggtgacgatt tgaattcggt
     2641 gacccactta gaggtttttg aaagtttaat cagataatga tacttgcaga gagactgagt
     2701 cactgctgtc agacgggagg ttccagtgct gggagagtag gctgtggtta cttcacaccc
     2761 gctgtaccct ttgctttata tctatacaaa tataaccttg ggtttgggtt tttgtttttt
     2821 cctgtgttgg ggctcaaact cagggcgttg tacatgttag gcaaatgttc taaaactgag
     2881 ctacatccca gctgtccaag cacagactta tatatgcccc ccttttaata aacattccaa
     2941 ctatgtggac acattc
//
