LOCUS       NP_599219                488 aa            linear   ROD 07-MAY-2024
DEFINITION  spermatogenesis-associated protein 6 precursor [Rattus norvegicus].
ACCESSION   NP_599219 XP_346748
VERSION     NP_599219.2
DBSOURCE    REFSEQ: accession NM_134392.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 488)
  AUTHORS   Yuan,S., Stratton,C.J., Bao,J., Zheng,H., Bhetwal,B.P.,
            Yanagimachi,R. and Yan,W.
  TITLE     Spata6 is required for normal assembly of the sperm connecting
            piece and tight head-tail conjunction
  JOURNAL   Proc Natl Acad Sci U S A 112 (5), E430-E439 (2015)
   PUBMED   25605924
REFERENCE   2  (residues 1 to 488)
  AUTHORS   Oh,C., Aho,H., Shamsadin,R., Nayernia,K., Muller,C., Sancken,U.,
            Szpirer,C., Engel,W. and Adham,I.M.
  TITLE     Characterization, expression pattern and chromosomal localization
            of the spermatogenesis associated 6 gene (Spata6)
  JOURNAL   Mol Hum Reprod 9 (6), 321-330 (2003)
   PUBMED   12771232
REFERENCE   3  (residues 1 to 488)
  AUTHORS   Yamano,Y., Ohyama,K., Sano,T., Ohta,M., Shimada,A., Hirakawa,Y.,
            Sugimoto,M. and Morishima,I.
  TITLE     A novel spermatogenesis-related factor-1 gene expressed in maturing
            rat testis
  JOURNAL   Biochem Biophys Res Commun 289 (4), 888-893 (2001)
   PUBMED   11735130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1 and BC158581.1.
            
            On Sep 12, 2012 this sequence version replaced NP_599219.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF291466.1, BC158581.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q35"
     Protein         1..488
                     /product="spermatogenesis-associated protein 6 precursor"
                     /note="spermatogenesis-associated protein 6;
                     kinesin-related protein HASH; spermatogenesis-related
                     factor 1"
                     /calculated_mol_wt=54152
     sig_peptide     1..17
                     /note="/evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
                     /calculated_mol_wt=1871
     Region          11..149
                     /region_name="SPATA6"
                     /note="Spermatogenesis-assoc protein 6; pfam14909"
                     /db_xref="CDD:464365"
     mat_peptide     18..488
                     /product="Spermatogenesis-associated protein 6.
                     /id=PRO_0000278443"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU5.2)"
                     /calculated_mol_wt=54152
     Region          175..225
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            217
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            219
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            265
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            274
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            325
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            343
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            346
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            354
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            424
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            465
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     Site            487
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q99MU5.2)"
     CDS             1..488
                     /gene="Spata6"
                     /gene_synonym="Hash"
                     /coded_by="NM_134392.2:206..1672"
                     /db_xref="GeneID:171413"
                     /db_xref="RGD:628657"
ORIGIN      
        1 mpkvkalqca laleirsvtc pgvvlkdked iylsicvfgq ykktqcvpat fplvfnarmv
       61 fekvfpeavd pgdvvaqley dtavfeliql vppvgetlst ydentrdfmf pgpnqisghh
      121 dsnrqvtmrr isglrgiapk lefsttsvit eclissrkcr tqdkftyhsa pvekphgrlq
      181 crtsrsqkkk sksperskyc intknyeqpt isskshspsp ytkrrmcels edtrrrlahl
      241 nlgpyefkke tdkppfvirh vdppspradn ffgspgrdce rdgwvrmhsd hphlgccrak
      301 dykvirsphg rdfedpferc edylsprtcs kpqhsartll vhsapsttpk hcaspvlnra
      361 slrerfhsdw csppncdeih drvkdvlksh qahgrhlcee rdpekedele lkrsllyrds
      421 aydsdpeyss fqrprgsfhl ddgecwsnra asckgkshrp vfensmdkmy rnlykkacss
      481 vshtqesf
//
