LOCUS       NM_001191824            1228 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus spermatogenesis associated 22 (Spata22), mRNA.
ACCESSION   NM_001191824 XM_340842
VERSION     NM_001191824.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1228)
  AUTHORS   Ishishita,S., Matsuda,Y. and Kitada,K.
  TITLE     Genetic evidence suggests that Spata22 is required for the
            maintenance of Rad51 foci in mammalian meiosis
  JOURNAL   Sci Rep 4, 6148 (2014)
   PUBMED   25142975
  REMARK    GeneRIF: Spata22 may function in regulating the post-invasion DNA
            synthesis through interacting with Rpa on the displaced strand.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1228)
  AUTHORS   Ishishita,S., Inui,T., Matsuda,Y., Serikawa,T. and Kitada,K.
  TITLE     Infertility associated with meiotic failure in the tremor rat
            (tm/tm) is caused by the deletion of spermatogenesis associated 22
  JOURNAL   Exp Anim 62 (3), 219-227 (2013)
   PUBMED   23903057
  REMARK    GeneRIF: It plays an important role in meiotic prophase I and its
            deletion causes infertility in rats.
REFERENCE   3  (bases 1 to 1228)
  AUTHORS   La Salle,S., Palmer,K., O'Brien,M., Schimenti,J.C., Eppig,J. and
            Handel,M.A.
  TITLE     Spata22, a novel vertebrate-specific gene, is required for meiotic
            progress in mouse germ cells
  JOURNAL   Biol Reprod 86 (2), 45 (2012)
   PUBMED   22011390
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Jul 17, 2010 this sequence version replaced XM_340842.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB236891.1, SRR26360186.182454.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                JAXUCZ010000010.1  58445333-58445375
            44-172              JAXUCZ010000010.1  58448277-58448405
            173-233             JAXUCZ010000010.1  58451572-58451632
            234-329             JAXUCZ010000010.1  58451754-58451849
            330-672             JAXUCZ010000010.1  58454573-58454915
            673-796             JAXUCZ010000010.1  58459634-58459757
            797-894             JAXUCZ010000010.1  58460764-58460861
            895-1228            JAXUCZ010000010.1  58461245-58461578
FEATURES             Location/Qualifiers
     source          1..1228
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..1228
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /note="spermatogenesis associated 22"
                     /db_xref="GeneID:360565"
                     /db_xref="RGD:1565378"
     CDS             1..1086
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /codon_start=1
                     /product="spermatogenesis-associated protein 22"
                     /protein_id="NP_001178753.1"
                     /db_xref="GeneID:360565"
                     /db_xref="RGD:1565378"
                     /translation="MKRNLNESSTRSTAGCLPVPLFNQKKRNRQPLTSNPLQSDPGIG
                     TVSDTYGFPSLPTDWAWEAVNPVVAPLKKTVNTGQIPASASYPLRIEDPVCKSIESNA
                     KRSQGGGGYRGNNRNTSSRTWDRNDFRPQHKTVSPAANSEFSSGPVNLGAQRQKQFQT
                     PEFPNLPGHKEAEVPRQTYLSKLPGSTMKGPDRASALQAFKPSFQQNPFNKTVLGDVP
                     RENSLKETTLYQLKEKDNSLRIISAVIESMKYWQAQVKKTVLLFEVLAVLDSAVTPGP
                     HYSKTFLMRDGKNILPCVFYEIDRELPRLIRGRVHRCVGHYDPHKNIFKCVSVRPASA
                     SEQKTFQAFVTIVDAEMKYHTKVMNEM"
     exon            1..43
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /inference="alignment:Splign:2.1.0"
     exon            44..172
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /inference="alignment:Splign:2.1.0"
     exon            173..233
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /inference="alignment:Splign:2.1.0"
     exon            234..329
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /inference="alignment:Splign:2.1.0"
     exon            330..672
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /inference="alignment:Splign:2.1.0"
     exon            673..796
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /inference="alignment:Splign:2.1.0"
     exon            797..894
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1228
                     /gene="Spata22"
                     /gene_synonym="RGD1565378; Sgn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaagagaa acttaaatga aagttcaact cgaagtacag caggctgttt gcctgtgccg
       61 ttgttcaatc agaaaaagag gaacagacag ccattaacgt ctaatccact tcagagtgat
      121 ccaggaattg gtactgtttc tgacacttat ggtttcccat ctctaccaac agattgggcg
      181 tgggaagctg tgaatccagt ggtggctcct ttaaagaaaa cagtgaatac agggcaaata
      241 ccagcttctg cttcttatcc cctgagaatt gaagatcctg tgtgtaaatc tattgagtca
      301 aacgctaaaa gaagccaagg tggcggggga tacagaggca acaacagaaa cactagctct
      361 agaacttggg atagaaatga tttccgacct cagcataaaa ctgtaagccc tgcggcaaac
      421 agtgagttca gttctggtcc agtgaatttg ggagctcaac gacaaaaaca gttccaaaca
      481 cctgaatttc ctaacttacc tggacacaaa gaagctgaag ttccccgaca gacatattta
      541 tcaaaactgc ctggctctac aatgaaaggt ccagacagag ccagcgcact gcaggcattt
      601 aaaccaagtt ttcaacaaaa tccatttaat aaaacagtgt tgggagatgt tccaagagaa
      661 aattctctga aggaaactac cttgtatcag ttaaaggaaa aagataattc tttaagaatt
      721 atttctgcag ttattgagag catgaagtat tggcaagcac aagtgaagaa aactgtactt
      781 ctttttgaag tattggctgt cctggattcg gctgtcacgc ctggcccaca ttattcaaag
      841 acttttctta tgagagatgg gaaaaatatt cttccatgtg tattttatga aattgatcgt
      901 gaacttccaa gactgattag aggccgagtt cacaggtgtg ttgggcacta tgacccacac
      961 aagaacattt tcaagtgtgt ttctgtcaga ccagcatctg cttctgaaca aaagactttt
     1021 caagcatttg ttacaattgt agatgccgag atgaaatatc atactaaagt aatgaatgaa
     1081 atgtaaatag tgacaaaggg aattacataa tatgaacaga agcatttact gttattaatt
     1141 taccacttgc atgattttat cactcttgtt ttctgtattt cacttctttt tatacaaata
     1201 aaaattttct tatagatttt catcaaaa
//
