LOCUS       NM_001191686            3986 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus spermatogenesis associated 13 (Spata13), mRNA.
ACCESSION   NM_001191686 XM_224253
VERSION     NM_001191686.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3986)
  AUTHORS   Evans,J.C., Robinson,C.M., Shi,M. and Webb,D.J.
  TITLE     The guanine nucleotide exchange factor (GEF) Asef2 promotes
            dendritic spine formation via Rac activation and
            spinophilin-dependent targeting
  JOURNAL   J Biol Chem 290 (16), 10295-10308 (2015)
   PUBMED   25750125
  REMARK    GeneRIF: The guanine nucleotide exchange factor (GEF) Asef2
            (Spata13) promotes dendritic spine formation via Rac activation and
            spinophilin-dependent targeting.
REFERENCE   2  (bases 1 to 3986)
  AUTHORS   Bristow,J.M., Sellers,M.H., Majumdar,D., Anderson,B., Hu,L. and
            Webb,D.J.
  TITLE     The Rho-family GEF Asef2 activates Rac to modulate adhesion and
            actin dynamics and thereby regulate cell migration
  JOURNAL   J Cell Sci 122 (Pt 24), 4535-4546 (2009)
   PUBMED   19934221
REFERENCE   3  (bases 1 to 3986)
  AUTHORS   Sagara,M., Kawasaki,Y., Iemura,S.I., Natsume,T., Takai,Y. and
            Akiyama,T.
  TITLE     Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal
            organization and are involved in HGF-induced cell migration
  JOURNAL   Oncogene 28 (10), 1357-1365 (2009)
   PUBMED   19151759
REFERENCE   4  (bases 1 to 3986)
  AUTHORS   Kawasaki,Y., Sagara,M., Shibata,Y., Shirouzu,M., Yokoyama,S. and
            Akiyama,T.
  TITLE     Identification and characterization of Asef2, a guanine-nucleotide
            exchange factor specific for Rac1 and Cdc42
  JOURNAL   Oncogene 26 (55), 7620-7267 (2007)
   PUBMED   17599059
REFERENCE   5  (bases 1 to 3986)
  AUTHORS   Hamann,M.J., Lubking,C.M., Luchini,D.N. and Billadeau,D.D.
  TITLE     Asef2 functions as a Cdc42 exchange factor and is stimulated by the
            release of an autoinhibitory module from a concealed C-terminal
            activation element
  JOURNAL   Mol Cell Biol 27 (4), 1380-1393 (2007)
   PUBMED   17145773
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Jul 17, 2010 this sequence version replaced XM_224253.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760386
                              [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               JAXUCZ010000015.1  38954658-38954758
            102-1808            JAXUCZ010000015.1  39009075-39010781
            1809-2171           JAXUCZ010000015.1  39025303-39025665
            2172-2316           JAXUCZ010000015.1  39027974-39028118
            2317-2453           JAXUCZ010000015.1  39065160-39065296
            2454-2633           JAXUCZ010000015.1  39067148-39067327
            2634-2819           JAXUCZ010000015.1  39067660-39067845
            2820-2999           JAXUCZ010000015.1  39070276-39070455
            3000-3232           JAXUCZ010000015.1  39072061-39072293
            3233-3362           JAXUCZ010000015.1  39073769-39073898
            3363-3735           JAXUCZ010000015.1  39075933-39076305
            3736-3810           JAXUCZ010000015.1  39078990-39079064
            3811-3986           JAXUCZ010000015.1  39080053-39080228
FEATURES             Location/Qualifiers
     source          1..3986
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..3986
                     /gene="Spata13"
                     /note="spermatogenesis associated 13"
                     /db_xref="GeneID:305938"
                     /db_xref="RGD:1307364"
     exon            1..101
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            102..1808
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     CDS             243..3986
                     /gene="Spata13"
                     /codon_start=1
                     /product="spermatogenesis-associated protein 13"
                     /protein_id="NP_001178615.1"
                     /db_xref="GeneID:305938"
                     /db_xref="RGD:1307364"
                     /translation="MTTAQDGHGQGATATCSASNPKAPKMVTSSACQNGGCKSSSSDP
                     EAGEARLSPSKLVRLFSGSRKRMNSNSERPRSVVVVGNSSTWNALASFRKMGSFKRLK
                     SSVLQGIQNREGAEVSKEESSGDQGRAAPNGTIAILGKGLGRCASLGPVGDGAGSDCS
                     DPEDTEDAFQRSTHRSRSIRRAYGLGRISLLDLGRQSVPEPAVCEIQVRDPEPSRAVP
                     LPRRSKSIDSLSVLKSSFKRKSASNLTELQGDRQVPSRTLSSFFTDSEKPGGSERRTR
                     RWRSPIRAKDFDRVLKLVSNVKEAAWKRETPRSAAPSPGSGLGDANPLLAPRSKLHDD
                     YSRRTSSSVEPDARRGGPLSSPCASAPCTAAPYTAPEPHLDVDTAVFPLESKSAQPLG
                     TDGPHTSSSSPIPTDTEGLSQASSEAHTGSQHPFDPVQLPTPLRPTTPKPQSPQSPGS
                     TKCPSSLSVLSLSSADSEERSEDAVHRQAGPMSLQDAVPAAAGDVGGENSESSFPSNP
                     DGATSPEERKEEVRVVTEDDWRQGSALEEEQNEAPRISRRKWGSGRRTGPRPLSDYGQ
                     LASRSLSIPEDAIATDPPGEDRVDRMHPASVTTTSQDPCTSSGCPRGGRRRRPISVIG
                     GVSFYGNTQAEDVENLLVQPAARPPVPAHQVPPYKAVSARLRPFTFSQSTPIGLDRVG
                     RRRQMKTSNVSSDGGAESSALVDDNGSEEDFSYEELCQANPRYLQPGGEQLAINELIS
                     DGSVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRNEDKEAWFPASFVRL
                     RVNQEELPEPCSSSQGEEQDEDASKARHKHPESQQQMRTNVIQEIMNTERVYIKHLKD
                     ICEGYIRQCRKHTGMFTVGQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGS
                     CFLQHQEGFAIYSEYCNNHPGACVELSNLMKQSKYRHFFEACRLLQQMIDIALDGFLL
                     TPVQKICKYPLQLAELLKYTTQEHSDYNNIKAAYEAMKNVACLINERKRKLESIDKIA
                     RWQVSIVGWEGLDILDRSSELIHSGELTKITRQGKTQQRVFFLFDHQLVSCKKDLLRR
                     DMLYYKGRMDMDEVDIVDVEDGRDKDWNLSMRNAFKLVSKATDEVHLFCARKQEDKAR
                     WLQAYADERRRVQEDQQMGMEISENQKKLAMLNAQKAGHGKSKGYNSCPVAPPHQSLP
                     PLHQRHITVPTSIPQQQVFALAEPKRKPSLFWHTFHKLTPFRK"
     exon            1809..2171
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            2172..2316
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            2317..2453
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            2454..2633
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            2634..2819
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            2820..2999
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            3000..3232
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            3233..3362
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            3363..3735
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            3736..3810
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
     exon            3811..3986
                     /gene="Spata13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctggcgag ctcgcggctc gaaccctgct ggagccggct ggggagcagg acctcttgga
       61 tacgctggct ttggagcttc ggaagtgcgg gaaccgccga ggcagtagct gtgactacgg
      121 atccagatgc acacagcaga tgtgagagcc aggctgctgt ccttggagat gaaggtttgg
      181 agctgggacc cccggttacc ggcgtcaatg ggggtttgaa ccaggctgcc cacgctaaga
      241 acatgacaac agcccaggat ggccatgggc aaggtgccac agccacttgt tcagcctcca
      301 acccgaaggc ccccaaaatg gtgacgtcct cagcatgtca gaatggaggc tgcaaaagca
      361 gctccagtga tcccgaagct ggggaagcca ggctcagtcc ttccaagctg gtacgtctct
      421 tctctggtag tcggaagagg atgaattcca actctgagag acctcgctcg gtggttgttg
      481 tggggaattc ctccacatgg aatgccctgg cctccttccg taaaatgggc tcttttaaaa
      541 gattgaaatc gtccgtcctt caaggaattc agaaccggga gggggcggaa gtttccaagg
      601 aggagtcatc aggagaccag ggaagggctg cccccaatgg caccattgcc atcctgggaa
      661 agggcctggg caggtgtgca tccttgggcc ctgtgggaga tggggccggg tctgactgct
      721 ctgaccctga ggacacagag gatgccttcc agaggagcac gcatcgttcg cgcagcatcc
      781 gcagggccta tggcctgggc cgcatcagcc tgctggacct ggggcggcag tcagtgccag
      841 agcctgcggt gtgtgagatc caagtgcgcg accctgagcc cagcagggcc gtgcctctgc
      901 cgcgcagaag caagagcatc gacagcttga gcgtcctgaa gagctccttc aagcgcaagt
      961 ctgcgtccaa cctcacggaa ctgcagggtg acaggcaggt tccctccagg accctgagca
     1021 gcttctttac agactctgag aagccgggtg gctcagagag aagaaccaga cgctggagga
     1081 gccccattag ggccaaggac ttcgacagag tcctgaaact ggtgagcaat gtcaaggagg
     1141 cggcctggaa gagggagacc cccaggagtg cagcccctag ccctggttcc ggtctggggg
     1201 atgcgaaccc actacttgcg ccaagaagca agctacacga tgactactcg cgccgtacca
     1261 gcagcagcgt ggagccagat gccaggcgtg gtggcccttt gtcctcaccc tgtgcctctg
     1321 caccatgcac tgctgctccc tacacagctc cagaacccca ccttgatgtg gatactgcag
     1381 tattccccct ggaaagtaaa agtgctcagc cactgggaac tgatggacct cacaccagca
     1441 gctcctcacc aatccccaca gacacagaag ggttgagcca ggcctccagt gaggcacata
     1501 ctggcagcca gcatcccttt gaccccgtgc agcttcccac tcctctgagg cccaccacac
     1561 ccaagcccca aagcccacag agcccaggga gtactaagtg ccccagcagt ctaagtgtac
     1621 tgtccctcag ttcggcggac agtgaagaac ggtcggagga tgccgtgcac aggcaggcag
     1681 gacccatgtc cctccaggat gccgttcccg ccgctgctgg tgatgttggg ggagaaaaca
     1741 gtgagagctc ttttccctcg aatcctgacg gagccaccag tccagaagag aggaaggagg
     1801 aggtaagggt ggtgactgag gatgactggc ggcagggctc agccctggag gaggagcaga
     1861 atgaggcacc tcgaatctcc aggaggaagt ggggctccgg gaggcgcacc gggccacgac
     1921 cgctgtctga ctatggccag ctggccagca gaagcttgtc cattcccgaa gatgccattg
     1981 caacagatcc tccaggtgaa gaccgcgtgg acaggatgca cccagcaagt gtgaccacca
     2041 ccagccagga tccatgcacc tcctcaggct gtcccagggg aggccggaga aggcgaccta
     2101 tatctgtgat cggaggggtc agcttctatg gcaacaccca ggcagaggat gtggagaacc
     2161 tcttggtcca accagcagcc aggcctcctg tgcctgcaca ccaagttcca ccctacaagg
     2221 ctgtgtctgc ccgcctccgg cccttcacct tctcccagag cactcccatc gggctggacc
     2281 gtgtggggcg tcgacggcag atgaaaacat ccaatgtctc ttcggatgga ggtgcggagt
     2341 cctcggcctt agtggatgac aatggtagtg aggaagactt cagctatgag gagctctgcc
     2401 aggccaaccc tcgatacctc cagccgggcg gggaacagct ggccatcaat gagctcatca
     2461 gcgatggcag cgtggtctgt gcagaagcac tgtgggacca tgtgaccatg gatgaccagg
     2521 aactaggctt caaggccgga gatgtcatcc aggtcctgga agcctccaac aaggactggt
     2581 ggtggggccg gaatgaagac aaagaggcct ggttccctgc cagctttgtt aggcttcgag
     2641 tcaaccagga ggagctgccc gagccctgca gcagctccca gggggaggag caggacgagg
     2701 acgccagcaa agcccgccac aagcaccccg agagccagca gcagatgcgg accaacgtca
     2761 tccaggagat catgaacacc gagcgagtgt acatcaagca cctcaaggac atctgcgagg
     2821 gctacatccg acagtgtcgt aagcacacgg gaatgttcac cgttgggcag ctagccacta
     2881 ttttcggaaa cattgaagac atttacaaat tccaaaggaa gtttctgaaa gacctcgaga
     2941 aacagtacaa caaagaagaa cctcacttaa gtgagatagg atcctgcttt cttcagcacc
     3001 aagagggctt tgccatctac tctgagtact gtaacaacca cccaggagcc tgtgtggagt
     3061 tgtccaacct catgaagcag agcaagtacc ggcacttctt tgaggcctgc cgcctgctcc
     3121 agcagatgat cgatatagcc ctggatggct tcctcctcac accggtgcag aagatctgca
     3181 aatacccgct gcagctggct gagctgctca agtacaccac ccaggagcac agcgactaca
     3241 acaatataaa ggcggcctat gaagccatga agaatgtggc ctgcttgatc aatgaacgca
     3301 agcgtaagct agagagcatc gacaagatcg cccgctggca ggtgtccatc gtgggctggg
     3361 agggcctgga cattctggac cgaagctccg agctgattca ctccggagag ctaaccaaga
     3421 tcaccaggca gggcaagacc cagcagcgag tcttcttcct gttcgaccac cagctggtgt
     3481 cctgcaagaa ggacctgctg cgcagggaca tgctatacta caagggccgc atggacatgg
     3541 atgaggtgga cattgtggat gtggaggatg ggcgggacaa ggactggaac ctcagcatgc
     3601 gaaacgcctt caagttggtc agcaaagcca cggatgaggt tcacctgttc tgcgccagaa
     3661 agcaggagga caaggccagg tggctgcagg cctatgcgga cgagaggcgg cgggtgcagg
     3721 aagaccagca gatgggaatg gaaatctcag aaaatcagaa gaaactcgcc atgttgaacg
     3781 cccagaaggc aggacatggg aaatctaaag gctacaacag ctgccctgtg gccccacccc
     3841 accagagcct gccacccctc caccagcgcc acatcactgt gcctaccagc atcccgcagc
     3901 agcaggtctt cgccttggct gagcccaaga ggaagccatc gctgttctgg cacaccttcc
     3961 acaaactcac cccattccgg aagtga
//
