LOCUS       NM_001191774            1565 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus Sp8 transcription factor (Sp8), mRNA.
ACCESSION   NM_001191774 XM_234724
VERSION     NM_001191774.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1565)
  AUTHORS   Kawakami,Y., Esteban,C.R., Matsui,T., Rodriguez-Leon,J., Kato,S.
            and Izpisua Belmonte,J.C.
  TITLE     Sp8 and Sp9, two closely related buttonhead-like transcription
            factors, regulate Fgf8 expression and limb outgrowth in vertebrate
            embryos
  JOURNAL   Development 131 (19), 4763-4774 (2004)
   PUBMED   15358670
REFERENCE   2  (bases 1 to 1565)
  AUTHORS   Treichel,D., Schock,F., Jackle,H., Gruss,P. and Mansouri,A.
  TITLE     mBtd is required to maintain signaling during murine limb
            development
  JOURNAL   Genes Dev 17 (21), 2630-2635 (2003)
   PUBMED   14597661
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jul 17, 2010 this sequence version replaced XM_234724.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.23970.1,
                                           SRR22582419.156099.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                JAXUCZ010000006.1  145959219-145959239
            22-1565             JAXUCZ010000006.1  145960281-145961824
FEATURES             Location/Qualifiers
     source          1..1565
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q33"
     gene            1..1565
                     /gene="Sp8"
                     /note="Sp8 transcription factor"
                     /db_xref="GeneID:299499"
                     /db_xref="RGD:1307619"
     CDS             1..1515
                     /gene="Sp8"
                     /note="trans-acting transcription factor 8"
                     /codon_start=1
                     /product="transcription factor Sp8"
                     /protein_id="NP_001178703.1"
                     /db_xref="GeneID:299499"
                     /db_xref="RGD:1307619"
                     /translation="MATSLLGEEPRLGSTPLAMLAATCNKIGSPSPSPSSLSDSSSSF
                     SKGFHPWKRSSSSSSGSCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVS
                     DSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGG
                     GGGGGSGAHSQDSSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAA
                     DVGSAGASSWWDVGAGWIDVQNPNGAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGL
                     SHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGSSMLSAGPAAPLG
                     GSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLK
                     AHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLS
                     KHVKTHSGGGGSAGSGGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE"
     exon            1..21
                     /gene="Sp8"
                     /inference="alignment:Splign:2.1.0"
     exon            22..1565
                     /gene="Sp8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcaactt cacttctagg ggaagaaccg aggttgggat ccactcctct ggccatgctt
       61 gctgctacct gtaataagat cggcagcccc agcccgtctc cctcctccct gtcggacagc
      121 tcttcttctt tcagtaaagg cttccaccct tggaaacgct cctcatcttc ctcctccggc
      181 agctgcaacg tagtgggttc cagtctctct agcttcggcg tgtcgggggc ctctcggaac
      241 ggcggttcgt cctccgccgc agcggcggcg gcggcggccg cggcggcggc ggcggccctg
      301 gtgtccgact cgtttagctg cggaggctcg cccggctcca gcgccttctc tctcacctcc
      361 agcagcgccg ccgcagcggc cgcagctgcc gcggccgccg cttccagctc gccctttgcc
      421 aacgactact ctgtgttcca ggccccgggc gtctcagggg gcagcggcgg cggcggcggg
      481 ggaggcggcg gcggttccgg agcgcactcg caggacagct cccatcagcc ggtgttcatc
      541 tccaaggtgc acacgtcggt ggacggactg caaggcatct acccgcgcgt gggaatggcg
      601 cacccgtatg agtcgtggtt caagccctcg cacccgggcc ttggtgccgc ggccgacgtg
      661 ggctccgcgg gcgcctccag ctggtgggat gtgggcgcgg gctggatcga cgtgcagaac
      721 cccaatgggg cagcagcgct gcccggctct ctgcacccgg ccgccggggg cctccagacg
      781 tcgctgcact caccgctggg aggctacaac tcggattact ccggcctgag ccactcggcc
      841 ttcagtagtg gtgcctcgtc gcacctgctc agccctgcag gacagcacct catggacggt
      901 ttcaagcccg tattgcccgg ctcgtacccg gattccgccc cttcgccgct ggccggcgcg
      961 ggcagctcta tgctgagcgc ggggcccgcg gcgcccttag gggggtctcc acgctcttct
     1021 gcgcgccgct actccggccg cgccacctgc gactgcccca actgccagga ggctgagcgt
     1081 ctgggcccag cgggagcgag cctgcgtcgc aaagggctgc atagctgcca catcccaggc
     1141 tgcggcaagg tgtacggcaa gacgtcgcac ctgaaggcgc acctgcgctg gcataccggc
     1201 gagcggccgt tcgtgtgcaa ttggctgttc tgcggtaagc gctttacgcg ctccgacgag
     1261 ctgcagcggc acctgcggac ccacacgggc gagaagcgct tcgcctgccc ggtgtgcaac
     1321 aaacgcttca tgcgcagcga ccacctgagc aagcacgtga agacacacag cggtggcggc
     1381 ggctcggcgg gctccggtgg cggcaagaag ggcagcgaca ccgacagcga gcacagcgcg
     1441 gcgggaagcc cgccttgcca ctcccctgag cttctgcagc ctccagagcc cggccaccgc
     1501 aatggcctgg agtgactgtc gcaatgcctc ccacctgagt cccgtcgggc ttgtgtgcct
     1561 ggact
//
