LOCUS       NM_053349               2022 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Rattus norvegicus SRY-box transcription factor 11 (Sox11), mRNA.
ACCESSION   NM_053349
VERSION     NM_053349.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2022)
  AUTHORS   Wang,L., Wang,B., Geng,X., Guo,X., Wang,T., Xu,J., Jiang,L. and
            Zhen,H.
  TITLE     microRNA-125b-5p alleviated CCI-induced neuropathic pain and
            modulated neuroinflammation via targeting SOX11
  JOURNAL   Synapse 78 (5), e22306 (2024)
   PUBMED   39135278
  REMARK    GeneRIF: microRNA-125b-5p alleviated CCI-induced neuropathic pain
            and modulated neuroinflammation via targeting SOX11.
REFERENCE   2  (bases 1 to 2022)
  AUTHORS   Liu,Q., Luo,J., Wang,H., Zhang,L., Guo,J. and Jin,G.
  TITLE     GAS5, a long noncoding RNA, contributes to annulus fibroblast
            osteogenic differentiation and apoptosis in intervertebral disk
            degeneration via the miR-221-3p/SOX11 axis
  JOURNAL   Aging (Albany NY) 16 (4), 3896-3914 (2024)
   PUBMED   38407972
  REMARK    GeneRIF: GAS5, a long noncoding RNA, contributes to annulus
            fibroblast osteogenic differentiation and apoptosis in
            intervertebral disk degeneration via the miR-221-3p/SOX11 axis.
REFERENCE   3  (bases 1 to 2022)
  AUTHORS   Su,D., Gao,Q., Guan,L., Sun,P., Li,Q., Shi,C. and Ma,X.
  TITLE     Downregulation of SOX11 in fetal heart tissue, under hyperglycemic
            environment, mediates cardiomyocytes apoptosis
  JOURNAL   J Biochem Mol Toxicol 35 (1), e22629 (2021)
   PUBMED   32935389
  REMARK    GeneRIF: Downregulation of SOX11 in fetal heart tissue, under
            hyperglycemic environment, mediates cardiomyocytes apoptosis.
REFERENCE   4  (bases 1 to 2022)
  AUTHORS   Meng,C.Y., Xue,F., Zhao,Z.Q., Hao,T., Guo,S.B. and Feng,W.
  TITLE     Influence of MicroRNA-141 on Inhibition of the Proliferation of
            Bone Marrow Mesenchymal Stem Cells in Steroid-Induced Osteonecrosis
            via SOX11
  JOURNAL   Orthop Surg 12 (1), 277-285 (2020)
   PUBMED   31916393
  REMARK    GeneRIF: MiR-141 inhibited the proliferation of bone marrow
            mesenchymal stem cells (BMSC) in steroid-induced avascular necrosis
            of the femoral head by targeting SOX11. Inhibition of miR-141
            upregulated the expression of SOX11 and promoted the proliferation
            of BMSC.
REFERENCE   5  (bases 1 to 2022)
  AUTHORS   Xu,L., Huang,S., Hou,Y., Liu,Y., Ni,M., Meng,F., Wang,K., Rui,Y.,
            Jiang,X. and Li,G.
  TITLE     Sox11-modified mesenchymal stem cells (MSCs) accelerate bone
            fracture healing: Sox11 regulates differentiation and migration of
            MSCs
  JOURNAL   FASEB J 29 (4), 1143-1152 (2015)
   PUBMED   25466891
  REMARK    GeneRIF: investigated the role of Sox11 in regulating trilineage
            differentiation (osteogenesis, adipogenesis, and chondrogenesis)
            and migration of mesenchymal stem cells
REFERENCE   6  (bases 1 to 2022)
  AUTHORS   Wiebe,M.S., Nowling,T.K. and Rizzino,A.
  TITLE     Identification of novel domains within Sox-2 and Sox-11 involved in
            autoinhibition of DNA binding and partnership specificity
  JOURNAL   J Biol Chem 278 (20), 17901-17911 (2003)
   PUBMED   12637543
REFERENCE   7  (bases 1 to 2022)
  AUTHORS   Plisov,S.Y., Ivanov,S.V., Yoshino,K., Dove,L.F., Plisova,T.M.,
            Higinbotham,K.G., Karavanova,I., Lerman,M. and Perantoni,A.O.
  TITLE     Mesenchymal-epithelial transition in the developing metanephric
            kidney: gene expression study by differential display
  JOURNAL   Genesis 27 (1), 22-31 (2000)
   PUBMED   10862152
  REMARK    Erratum:[Genesis 2000 Jul;27(3):136]
REFERENCE   8  (bases 1 to 2022)
  AUTHORS   Tchenio,T., Casella,J.F. and Heidmann,T.
  TITLE     Members of the SRY family regulate the human LINE retrotransposons
  JOURNAL   Nucleic Acids Res 28 (2), 411-415 (2000)
   PUBMED   10606637
REFERENCE   9  (bases 1 to 2022)
  AUTHORS   Azuma,T., Ao,S., Saito,Y., Yano,K., Seki,N., Wakao,H., Masuho,Y.
            and Muramatsu,M.
  TITLE     Human SOX11, an upregulated gene during the neural differentiation,
            has a long 3' untranslated region
  JOURNAL   DNA Res 6 (5), 357-360 (1999)
   PUBMED   10574465
REFERENCE   10 (bases 1 to 2022)
  AUTHORS   Kuhlbrodt,K., Herbarth,B., Sock,E., Enderich,J.,
            Hermans-Borgmeyer,I. and Wegner,M.
  TITLE     Cooperative function of POU proteins and SOX proteins in glial
            cells
  JOURNAL   J Biol Chem 273 (26), 16050-16057 (1998)
   PUBMED   9632656
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Nov 26, 2020 this sequence version replaced NM_053349.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AJ004858.1, SRR21887622.2567352.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2022              JAXUCZ010000006.1  49736773-49738794   c
FEATURES             Location/Qualifiers
     source          1..2022
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q16"
     gene            1..2022
                     /gene="Sox11"
                     /note="SRY-box transcription factor 11"
                     /db_xref="GeneID:84046"
                     /db_xref="RGD:69351"
     exon            1..2022
                     /gene="Sox11"
                     /inference="alignment:Splign:2.1.0"
     CDS             303..1490
                     /gene="Sox11"
                     /note="SRY-box containing gene 11; SRY (sex determining
                     region Y)-box 11; SRY box 11"
                     /codon_start=1
                     /product="transcription factor SOX-11"
                     /protein_id="NP_445801.1"
                     /db_xref="GeneID:84046"
                     /db_xref="RGD:69351"
                     /translation="MVQQAESSEAESNLPRDALDTEEGEFMACSPVALDESDPDWCKT
                     ASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA
                     ERLRLKHMADYPDYKYRPRKKPKTDPAAKPSAGQSPDKSAAGAKAAKGPGKKCAKLKA
                     PAGKAGAGKAAQPGDCGAGKAAKCVFLDDDDEEDDEDDELQLRPKPDADDDDDEPAHS
                     HLLPPPAQQQPPQLLRRYSVAKVPASPTLSSAAESPEGASLYDEVRAGGRLYYSFKNI
                     TKQQPPPAPPALSPASSRCVSTSSSSGSSSGSGAEDADDLMFDLSLNFSQGAHSACEQ
                     PLGAGAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWLEANFSDLV
                     FTY"
ORIGIN      
        1 tttttgcaga agaagcgcgc gcgcctggga gtgcttgggg tccggcgctt gcggcggctg
       61 ccaggagtgg gagagcgaga aatcaagcga gtgagagaga gagcgcgcgc gggtcccggg
      121 ccgccgccgc ctcctctccg gtcgccgcag ccgccgccgc agcagggaac gggaccgggg
      181 gggagggggg cagccgcgga cccgcggggc caaggacttt gcaacttgcc ggagaaggtg
      241 gaggggcggg agggggaggg gcgcccgcgc aggagaccga gcgcccagcc ccgccgcgga
      301 ccatggtgca gcaggccgag agctcggaag ccgagagcaa cctgccccgg gacgcgctgg
      361 acaccgagga gggcgagttc atggcgtgca gcccggtggc cctggatgag agcgacccgg
      421 actggtgcaa gacggcgtcg ggccacatca aacggcccat gaacgccttc atggtgtggt
      481 ccaagatcga gcgcaggaag atcatggagc agtcgcccga catgcataac gccgagatct
      541 ccaagaggct gggcaagcgt tggaagatgc tgaaggacag cgagaagatc ccgttcatcc
      601 gggaggcgga gcgcctgcgc ctcaagcaca tggctgatta tcccgactac aagtaccggc
      661 cgcgcaaaaa gcccaagacg gacccagccg ccaagcccag cgcgggccag agcccggaca
      721 agagcgcggc gggcgctaag gcagccaagg gcccgggcaa gaagtgcgcc aagctcaagg
      781 cgcctgcggg caaggcgggc gcaggcaagg cggcgcagcc tggggactgc ggcgcgggca
      841 aggcagccaa gtgcgtcttc ctggacgacg atgatgaaga ggacgacgag gacgacgagc
      901 tgcagctacg gcccaagccg gacgcagacg acgacgacga cgagcccgcg cactcgcacc
      961 tgctgccgcc accggcgcag cagcagcccc ctcagctgct gaggcgctac agcgtggcca
     1021 aggtgcccgc cagccccacg ctcagcagtg ccgccgagtc ccccgagggc gcgagcctgt
     1081 acgacgaagt gcgcgcgggc ggccggctct actacagctt caagaacatc accaagcagc
     1141 agcctccgcc cgcgcctccc gcgctgtcgc ccgcgtcctc gcgctgcgtg tccacctcct
     1201 catccagcgg cagcagcagc ggcagcggcg ccgaggatgc cgacgacctc atgttcgacc
     1261 tgagcttgaa tttctcccag ggcgcgcaca gcgcctgcga gcagccactg ggcgcgggag
     1321 cggcggggaa cctgtccctg tcgctggtgg ataaggacct ggattccttc agcgagggca
     1381 gcctgggctc ccacttcgag ttccccgact actgcacgcc ggagctgagc gagatgatcg
     1441 cgggggactg gctggaggcg aacttctccg acctggtgtt cacgtattga ggggcacagg
     1501 gctcctcggg aggcagtcgt ggcggtcagg ataaagagga tggtgggggg agggggagaa
     1561 gatgctcatg gtcagagatg tggcgcagag aaattggaaa cggtgatgaa atgttggagt
     1621 taaagtgaaa tgagtagttt taaacagatt ttccaggttt ttttttttaa tcttttaatt
     1681 tttaaaaaaa ttttttggtc tccccactct tcccttcctt tatcgtgtct caaggtagtt
     1741 gcacacctag tctggagttg tgatttcccc cacccgtaaa aaaatcgtgt tttgtaattt
     1801 ctatttcttt ttcctgaaat tcgtgattgc aacaaaggcg gaggggaccg ggcgggggag
     1861 gggaggaggc cccgctccgg aaggcgctgt ttgaagctcg tggctctttg aagtctgaaa
     1921 gacgtcggca gaggaccctt tagacggcac aactgttact ctagggagtt gatatttttt
     1981 ttttcttaag agatttaaaa aggaactggt gatttaaaaa aa
//
