LOCUS       XM_017591474            2209 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus sorbitol dehydrogenase (Sord),
            transcript variant X1, mRNA.
ACCESSION   XM_017591474
VERSION     XM_017591474.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017591474.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017591474.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2209
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2209
                     /gene="Sord"
                     /gene_synonym="SDH; XDH"
                     /note="sorbitol dehydrogenase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 47 ESTs, 7 long SRA reads, 6 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 55 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:24788"
                     /db_xref="RGD:3734"
     CDS             211..1227
                     /gene="Sord"
                     /gene_synonym="SDH; XDH"
                     /codon_start=1
                     /product="sorbitol dehydrogenase isoform X1"
                     /protein_id="XP_017446963.1"
                     /db_xref="GeneID:24788"
                     /db_xref="RGD:3734"
                     /translation="MDLENYPIPELGPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVK
                     KPMVLGHEAAGTVTKVGPMVKHLKPGDRVAIEPGVPREIDEFCKIGRYNLTPSIFFCA
                     TPPDDGNLCRFYKHSADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVC
                     GAGPIGIVTLLVAKAMGASQVVVIDLSASRLAKAKEVGADFTIQVAKETPHDIAKKVE
                     SVLGSKPEVTIECTGAESSVQTGIYATHSGGTLVVVGMGPEMINLPLVHAAVREVDIK
                     GVFRYCNTWPMAVSMLASKTLNVKPLVTHRFPLEKAVEAFETAKKGLGLKVMIKCDPN
                     DQNP"
ORIGIN      
        1 agtcctgcgg gtgccaggcg ctttgccggt ttgatggagt aaccgaagcc gctgcaacac
       61 ttagcggttt ttcagagcgc tagcggcggc ctgcctgcag cagcactgtt cccgttagta
      121 acacagaaca cccgcgctcc acctcagacc taaacttgct gttggaggat tcttggtgct
      181 agcccggtct tctgcagcca caaatccaca atggacttgg agaactaccc aatccctgag
      241 ctgggcccaa atgatgtgtt actaaagatg cattcggtgg ggatctgtgg ctcggatgtt
      301 cactactggg agcatggccg aattggggac ttcgttgtga aaaagccaat ggtgcttggg
      361 catgaagctg ctggaacagt cacaaaagtg ggaccgatgg tgaaacatct aaaaccagga
      421 gatcgggtgg ccatcgagcc tggcgttccc cgagaaatag atgaattctg caagatcggc
      481 cgatacaatc tgacgccatc catcttcttc tgtgccacgc ccccagatga tgggaacctc
      541 tgccgcttct acaagcacag cgctgacttc tgctacaagc ttcctgatag tgtcaccttt
      601 gaagaagggg ccctgattga gcctctctct gtggggatct atgcctgccg tcgaggttcg
      661 gtttccctgg ggaacaaggt ccttgtgtgt ggagctgggc caattgggat agtcactttg
      721 cttgtggcca aagcaatggg agcttctcaa gtagtggtga ttgacctctc tgcttctcgg
      781 ttagccaagg ccaaggaagt tggagcagac tttaccatcc aggttgccaa agagacccct
      841 cacgacattg ccaagaaggt ggaaagtgtg ctggggagca agccagaggt caccatcgaa
      901 tgcacgggag cggagtcctc tgtccagacg ggcatctatg ccactcactc tggcgggacc
      961 ttggtggttg tgggaatggg ccccgagatg atcaatttac ccctagtgca cgcagctgtg
     1021 cgggaggtgg acatcaaagg cgtgtttcga tactgcaaca cgtggccgat ggcagtttcc
     1081 atgcttgcat cgaagacttt gaatgtaaag cccttagtga cccataggtt ccccctggag
     1141 aaggctgtag aagcctttga aacagccaaa aagggactgg ggctgaaagt tatgatcaag
     1201 tgtgacccca atgaccagaa cccctaaatg tgattgctct atgcccttag cccactctct
     1261 cagcatctaa gggctaaatg gaccagaagg ggaagccatt aatgcagaac cttctttttg
     1321 aatggtagga ataataaact cataagccga gagccttaga ggagctggcg tgccttaaag
     1381 acagaagtag gggcaccttg ggggacctcg tagccagaat gagatgcgta tactgagtaa
     1441 agtctagaac caagagtctg gcagagaggt cccggaaatg ccctttctca gtaccttctt
     1501 tgggtgagga gacgaagcat gccttcgtcc atgttccaat gtgggtgcca gagagtgggg
     1561 ctaacatgga gaaatgacgt cattaacatg ggagtggccc cagagctgtt cagagcacag
     1621 tgtttcccaa gtgtcatttg atttgagggg aataagggca ctcagctctg cctcagctca
     1681 gaattctgtc cttacatttg caaagtggag gccttcttcc caacagtgct cattcatgtt
     1741 caggagcagt actggttgct aagcaaccag gagacttcca cccaaagatc ctaaatccag
     1801 cctaactcat acaagagggc cacaggaggg cttgagtttc ccactcacag gattcgcctc
     1861 ctctcccagg ctcactccta ggcaattatt atcccatccc actcagaaga tgctcccctt
     1921 ctcggctgtt aaggctagtg atatctgatg gatgggtatc acagagccta attaaattat
     1981 ggggcttttc tttataagat ctgggtccaa atcatgccct ttgtgatctt aagataatca
     2041 agaagagcac agtaactgtg gtgtaacttg ggctgcagtc tgtaatccac ctcttcagct
     2101 atgagtaggg gacacgtgaa aaaaaaaaga ctctgctgga gaagaccatg gccaacacct
     2161 gagctttctc aaactgcttc caatagtaaa ttctgtcgct ggtgttgaa
//
