LOCUS       NM_001034961            2365 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus spermatogenesis and oogenesis specific basic
            helix-loop-helix 2 (Sohlh2), mRNA.
ACCESSION   NM_001034961
VERSION     NM_001034961.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2365)
  AUTHORS   Shin,Y.H., Ren,Y., Suzuki,H., Golnoski,K.J., Ahn,H.W., Mico,V. and
            Rajkovic,A.
  TITLE     Transcription factors SOHLH1 and SOHLH2 coordinate oocyte
            differentiation without affecting meiosis I
  JOURNAL   J Clin Invest 127 (6), 2106-2117 (2017)
   PUBMED   28504655
REFERENCE   2  (bases 1 to 2365)
  AUTHORS   Barrios,F., Filipponi,D., Campolo,F., Gori,M., Bramucci,F.,
            Pellegrini,M., Ottolenghi,S., Rossi,P., Jannini,E.A. and Dolci,S.
  TITLE     SOHLH1 and SOHLH2 control Kit expression during postnatal male germ
            cell development
  JOURNAL   J Cell Sci 125 (Pt 6), 1455-1464 (2012)
   PUBMED   22328502
REFERENCE   3  (bases 1 to 2365)
  AUTHORS   Suzuki,H., Ahn,H.W., Chu,T., Bowden,W., Gassei,K., Orwig,K. and
            Rajkovic,A.
  TITLE     SOHLH1 and SOHLH2 coordinate spermatogonial differentiation
  JOURNAL   Dev Biol 361 (2), 301-312 (2012)
   PUBMED   22056784
REFERENCE   4  (bases 1 to 2365)
  AUTHORS   Choi,Y., Yuan,D. and Rajkovic,A.
  TITLE     Germ cell-specific transcriptional regulator sohlh2 is essential
            for early mouse folliculogenesis and oocyte-specific gene
            expression
  JOURNAL   Biol Reprod 79 (6), 1176-1182 (2008)
   PUBMED   18753606
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC104697.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC104697.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2365
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q26"
     gene            1..2365
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /note="spermatogenesis and oogenesis specific basic
                     helix-loop-helix 2"
                     /db_xref="GeneID:619575"
                     /db_xref="RGD:1589577"
     exon            1..80
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..1421
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /codon_start=1
                     /product="spermatogenesis- and oogenesis-specific basic
                     helix-loop-helix-containing protein 2"
                     /protein_id="NP_001030133.1"
                     /db_xref="GeneID:619575"
                     /db_xref="RGD:1589577"
                     /translation="MADRISTGELGRRPGQGRVDLLLVGDATRYFLAGSVQKFFSSTA
                     QITLTISNVKKVAALLAANSFDIIFLKVTSTLTAEEQEAVRLIRSGKKKNTHLLFAFV
                     IPEKLRGYISDYGADISFNEPLTLEKVNTVINYWKTYFTNTDMGNTELPPECRLYFQT
                     SCSELGGHFPTDLFLCSELLNNDTGLGLKAPLSSPERNKKASFLHSSKEKLRRERIKF
                     CCEQLRTLLPYVKGRKSDVASVIEATVDYVKQVRESLSPAIMAQITESLQSNKRFSKR
                     QMPIELFLPCTATSQRGDAMLTSAFSPVQEIQLLADQGLNVYSMPAAGGPLEEAVRGQ
                     PGSVSEDLYKTRVPSTTLSLNSFHAVRYCSGPVSPHEAAARTNQNISIYLPPTGPSVS
                     SFTPQHCNAMLCPTRPASSSCLCTSGHELPASSRTASSSIFRGFRESDSGHQASQQPT
                     GPSLQPQDSSYF"
     exon            81..295
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            296..357
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            358..462
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            463..559
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            560..670
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            671..818
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            819..907
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1029
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1274
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..2339
                     /gene="Sohlh2"
                     /gene_synonym="RGD1304752"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccgccaag aagctgcaga gcagtagacg ccatggccga caggatcagc actggggagc
       61 taggccggag gccggggcag ggaagagtag accttttgct agttggagat gccacacgat
      121 atttcctggc tggttctgtg cagaaattct tttccagcac agcacagatc accctgacca
      181 ttagcaacgt gaagaaggta gctgcgcttc tggctgctaa ctcgtttgac ataatcttct
      241 tgaaggtgac ttctacctta actgcagagg agcaggaggc cgtcagattg attagatctg
      301 gcaagaagaa aaacacacat ttgctgtttg cttttgtaat acctgaaaaa cttagaggct
      361 atatttcaga ttatggagct gatattagtt tcaatgagcc actgaccttg gaaaaagtga
      421 acactgtgat aaactactgg aaaacgtatt tcacaaatac ggatatgggg aacactgagt
      481 tgcctccaga atgcagactc tacttccaga cttcctgcag cgaactcgga gggcatttcc
      541 ctacagatct gtttctttgc tctgaactgc tgaacaatga cactggactt ggattaaagg
      601 ccccgctgtc gagtccagag agaaacaaaa aggcttcttt tcttcactca agcaaagaaa
      661 agctgagacg agagcgcatc aagttttgct gtgagcagct gcgcaccctc ctgccatacg
      721 tcaaggggag gaagagtgat gtggcttccg tcatcgaggc cacagttgat tatgtgaagc
      781 aggtccggga gtctctctcg ccagccatta tggcccagat tacagaatcc cttcagagca
      841 ataagaggtt ttctaagaga cagatgccca tcgagctgtt cctcccctgc acagccacat
      901 cacagagggg agatgctatg ctgacaagtg ctttctcacc tgtgcaagag atccagctcc
      961 tggctgacca gggcttgaat gtctattcca tgcctgctgc aggaggacct ttggaggaag
     1021 ctgtgagagg tcagccgggc tctgtttcag aggatcttta taagactcga gtccccagca
     1081 cgactctctc tctgaactcc ttccatgctg tcagatactg ctctggaccc gtctctcccc
     1141 atgaggcagc tgccagaaca aaccagaaca tttccattta tttaccaccc actgggccca
     1201 gtgtgtccag ctttactcct cagcactgca atgccatgct ttgcccaaca cgcccagcca
     1261 gctccagttg tctgtgcact tccggccatg agctcccagc cagttctcgc actgcctcat
     1321 ccagcatctt tcgtgggttc cgagaatcag actcgggtca ccaggcttct cagcaaccca
     1381 ctgggccgtc tctgcagcct caagacagca gttactttta agaaaaatta atgtttgtaa
     1441 acatgtagtt tagttgcctg aagacgccag ttggctttat taactttcat gatacagaaa
     1501 tgcatttgtg acattgtgag taaggatggg ttagactcaa ttactgtgtt cttctccctc
     1561 cctcccaaca gtttggggcg taaacagtcc gtgtgtgggg ctcatgttct agaccacata
     1621 ctgggcacac ttgttcagtt gaggaagaag ggacaaagaa agatatttga aagctgctga
     1681 tcgtgttgtc tgataaatgt gctagaacct tccaaagata catagaaaga tagtagatgg
     1741 cagtgacagc cttgtcactc aggcatcttc atccatgtcg ggatttccca atgcatcagg
     1801 aatctgcagg ccgagtgaca cccccccccc acacacacac acaaattcat tttaccaaaa
     1861 atataattgt tcacgttgtg aaaaacatac tacaaagaat acctatgtgg aggtaaacat
     1921 ctaagaccag gacgtcccag ggtagctgta gcctgggggt tgcttctgtc attgatttct
     1981 agttggtatc ttctctagat ttggcatttt ggagagcccc cttcttcatt catcatccac
     2041 actaaaataa tcagggagat gtggagcaac tgtgcttgtc catttggtga ttccagataa
     2101 actgatatgc ttttgattgc attttgcaat cttgtgagtg gaatggcagc caggaggggc
     2161 acttactttt ccttgctggg ccacagataa gtgcttggtc ctgtccttgt acgtgtgttt
     2221 gctggaaacc aggaaagaga gggggggtgg ttttatattt cactgaaatg ttcttacaca
     2281 aacgttttat tgttaaagtg taatccattg ttttgtttaa taaaatactt tctcttttaa
     2341 aaaaaaaaaa aaaaaaaaaa aaaaa
//
